LIVIVO - Search results -

Search results

Result 1 - 10 of total 250

Search options

Article ; Online: FAPI PET/CT provides higher uptake and better target to back ground in recurrent and metastatic tumors of patients with Iodine refractory papillary thyroid cancer compared with FDG PET CT.

Nourbakhsh, Shaghayegh / Salehi, Yalda / Farzanehfar, Saeed / Ghaletaki, Reza / Bakhshi Kashi, Mohsen / Abbasi, Mehrshad

Nuklearmedizin. Nuclear medicine

2024

Abstract: Purpose: The role of fibroblast activation protein inhibitor (FAPI) PET CT scan is not well documented in papillary thyroid cancer (PTC) patients. Patients with radioiodine refractory PTC and high thyroglobulin levels need PET/CT scan which is generally ...

Title translation	FAPI-PET/CT bietet eine höhere Aufnahme und einen besseren Target-to-Background bei rezidivierenden und metastasierenden Tumoren von Patienten mit Iod-refraktärem papillärem Schilddrüsenkrebs im Vergleich zu FDG-PET/CT.
Abstract	Purpose: The role of fibroblast activation protein inhibitor (FAPI) PET CT scan is not well documented in papillary thyroid cancer (PTC) patients. Patients with radioiodine refractory PTC and high thyroglobulin levels need PET/CT scan which is generally done by 18F FDG. In the current study, the diagnostic performance of 68Ga FAPI and FDG PET/CT scans were compared head to head in patients with radioiodine refractory PTC. Method: Fourteen patients with negative whole body Iodine scans and high thyroglobulin levels underwent whole body PET scans with, respectively, 120-310 and 145-370 MBq 68Ga FAPI-46 and 18F FDG. SUVmax of the back ground in the blood pool and liver and the hottest, largest and average neck, mediastinum, lung and bone lesions were calculated and compared. Result: Ten patients had at least one active (SUVmax>blood pool) lesion similarly in two scans. The liver and blood pool SUVmax values were 1.25(0.2) and 1.7(0.2) in FAPI and 2.65(0.2) and 2.0(0.2) in FDG PET images, respectively. The difference was significant (p=0.001). Standard SUV of the hottest lesion to liver was above 3 in all FAPI scans but in half of FDG scans. Target lesion number and intensity were similar between two PET studies but in a patient out of 5 pulmonary metastatic patients, pulmonary nodules were negative (SUVmax=0.9) in FDG while positive (SUVmax= 3.8) in FAPI images (i.e. 20% patient upstaged). Conclusion: FAPI accumulates in the recurrent and metastatic lesions of patients with Iodine refractory PTC at least as well as FDG with particular privileges as lower injected activity and lower back ground.
Language	English
Publishing date	2024-01-08
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2030804-8
ISSN	2567-6407 ; 0029-5566
ISSN (online)	2567-6407
ISSN	0029-5566
DOI	10.1055/a-2185-7746
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Biodegradation of crystal violet dye by

Zahmatkesh Anbarani, Mohaddeseh / Nourbakhsh, Sima / Toolabi, Ali / Bonyadi, Ziaeddin

Heliyon

2023 Volume 9, Issue 9, Page(s) e19460

Abstract: Crystal violet (CV) is an azo dye with cationic nature, belonging to the triphenylmethane group. This study was designed to optimize CV removal ... ...

Abstract	Crystal violet (CV) is an azo dye with cationic nature, belonging to the triphenylmethane group. This study was designed to optimize CV removal by
Language	English
Publishing date	2023-08-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e19460
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Onion Germplasm Possesses Lower Early Season Thrips Numbers

Shahabeddin Nourbakhsh, Seyed / Cramer, Christopher S.

Horticulturae. 2022 Jan. 29, v. 8, no. 2

2022

Abstract: Onion is one of the most valuable vegetable crops in the US. Onion thrips were identified as one of the main threats to the US onion industry. An integrated approach, including host plant tolerance, is required. For this study, four New Mexico State ... ...

Abstract	Onion is one of the most valuable vegetable crops in the US. Onion thrips were identified as one of the main threats to the US onion industry. An integrated approach, including host plant tolerance, is required. For this study, four New Mexico State University breeding lines, along with two thrips-attractive cultivars, were evaluated for their attractiveness to thrips. In addition, this study observed thrips population dynamics throughout the growing season and the relationship between onion plant size and thrips attractiveness. The experiment was designed as a randomized complete block design with three blocks, each containing four replications. Thrips-infested bulbs were used to ensure the presence of thrips and thrips-attractive plants were used to ensure equal thrips distribution throughout the field. Ten plants were randomly selected from each plot and thrips and leaf numbers were counted multiple times through the growing season. Plants of NMSU breeding lines were observed to have fewer thrips, be more tolerant to thrips pressure and produce more leaves and larger bulbs than thrips-attractive entries. Early in the growing season, leaf number was not a determining factor in thrips population dynamics. The larger bulb weights of the breeding lines allowed them to maintain their market value. A delay in thrips population buildup in plants of the breeding lines may result in the critical threshold for spraying for thrips being reached later in these lines. This would potentially allow for fewer pesticide applications by growers, increasing growers’ profits and ensuring a more environmentally friendly approach to plant production.
Keywords	Thrips tabaci ; bulbs ; cultivars ; germplasm ; host plants ; industry ; leaves ; market value ; onions ; pesticides ; population dynamics ; New Mexico
Language	English
Dates of publication	2022-0129
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2813983-5
ISSN	2311-7524
ISSN	2311-7524
DOI	10.3390/horticulturae8020123
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Modeling the Protective Role of Bacterial Lipopolysaccharides against Membrane-Rupturing Peptides.

Nourbakhsh, Shokoofeh / Yu, Liu / Ha, Bae-Yeun

The journal of physical chemistry. B

2021 Volume 125, Issue 31, Page(s) 8839–8854

Abstract: Lipopolysaccharide (LPS) is a key surface component of Gram-negative bacteria, populating the outer layer of their outer membrane. A number of experimental studies highlight its protective role against harmful molecules such as antibiotics and ... ...

Abstract	Lipopolysaccharide (LPS) is a key surface component of Gram-negative bacteria, populating the outer layer of their outer membrane. A number of experimental studies highlight its protective role against harmful molecules such as antibiotics and antimicrobial peptides (AMPs). In this work, we present a theoretical model for describing the interaction between LPS and cationic antimicrobial peptides, which combines the following two key features. The polysaccharide part is viewed as forming a polymer brush, exerting an osmotic pressure on inclusions such as antimicrobial peptides. The charged groups on LPS (those in lipid A and the two Kdo groups in the inner core) form electrostatic binding sites for cationic AMPs or cations. Using the resulting model, we offer a quantitative picture of how the brush component enhances the protective role of LPS against magainin-like peptides, in the presence of divalent cations such as Mg
MeSH term(s)	Anti-Bacterial Agents ; Antimicrobial Cationic Peptides ; Gram-Negative Bacteria ; Lipopolysaccharides ; Magainins ; Static Electricity
Chemical Substances	Anti-Bacterial Agents ; Antimicrobial Cationic Peptides ; Lipopolysaccharides ; Magainins
Language	English
Publishing date	2021-07-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1520-5207
ISSN (online)	1520-5207
DOI	10.1021/acs.jpcb.1c02330
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Regular cannabis use is associated with history of childhood and lifetime trauma in a non-clinical community sample.

Bassir Nia, Anahita / Weleff, Jeremy / Fogelman, Nia / Nourbakhsh, Sormeh / Sinha, Rajita

Journal of psychiatric research

2023 Volume 159, Page(s) 159–164

Abstract: Higher rate of substance use, including cannabis, has been reported in individuals with a history of childhood trauma, but less is known about the association between cannabis use with lifetime history of trauma and chronic stress, and potential gender ... ...

Abstract	Higher rate of substance use, including cannabis, has been reported in individuals with a history of childhood trauma, but less is known about the association between cannabis use with lifetime history of trauma and chronic stress, and potential gender differences in this association. This study systematically examined this association in a cross-sectional study of 841 individuals recruited between 2007 and 2012 from the community in New Haven, Connecticut. The Cumulative Adversity Index (CAI) was used to measure cumulative lifetime major life events, life trauma, and recent life events and chronic stress. Childhood Trauma Questionnaire (CTQ) was used to measure childhood trauma. Current and regular use of drugs were assessed using self-report questionnaires and objectively verified with urine drug testing. Higher rates of childhood trauma as well as lifetime trauma, and major life events were found in cannabis users, compared to non-users. The association between cannabis use with childhood trauma (total CTQ scores) was significant after controlling for age, gender, ethnicity and regular use of alcohol or cocaine. In logistic regression analysis, cannabis use had a significant positive association with major life events and lifetime trauma, but not with chronic stress, controlling for confounding factors including age, gender, ethnicity, and regular use of alcohol and cocaine. When analyzed separately, only in women the association between cannabis use and childhood trauma was significant. These associations point to further assessment of the impact of these gender differences on neurobiology of stress and cannabis misuse risk.
MeSH term(s)	Humans ; Female ; Cannabis ; Cross-Sectional Studies ; Substance-Related Disorders ; Surveys and Questionnaires ; Cocaine
Chemical Substances	Cocaine (I5Y540LHVR)
Language	English
Publishing date	2023-01-28
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	3148-3
ISSN	1879-1379 ; 0022-3956
ISSN (online)	1879-1379
ISSN	0022-3956
DOI	10.1016/j.jpsychires.2023.01.036
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui I Zs.243: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Combined simultaneous photorefractive keratectomy and collagen cross-linking in keratoconus suspect patients.

Koosha, N / Fathian, A / Peyman, A / Nourbakhsh, S-A / Noorshargh, P / Pourazizi, M

Journal francais d'ophtalmologie

2023 Volume 46, Issue 8, Page(s) 921–928

Abstract: Purpose: To evaluate the safety and efficacy of combined simultaneous photorefractive keratectomy (PRK) with collagen cross-linking (CXL) in keratoconus suspects (KCS).: Methods: This was a retrospective, non-randomized study of KCS patients who ... ...

Abstract	Purpose: To evaluate the safety and efficacy of combined simultaneous photorefractive keratectomy (PRK) with collagen cross-linking (CXL) in keratoconus suspects (KCS). Methods: This was a retrospective, non-randomized study of KCS patients who underwent combined simultaneous PRK with CXL. The efficacy, safety, refractive outcomes, and corneal wavefront aberration changes were assessed after the surgery and compared with existing preoperative data. Results: Fifty-six eyes of 28 patients, including 20 females (71.4%), with a mean age of 30.92±4.09 years, were enrolled. The mean follow-up was 19.46±8.48 months (range: 7-35). At the conclusion of the study, mean uncorrected distance visual acuity LogMAR improved from 0.89±0.44 preoperatively to 0.04±0.09 postoperatively (P<0.001). In addition, a statistically significant corneal flattening was observed postoperatively, with a decrease in manifest refraction. A statistically significant increase was found in higher-order aberrations (P<0.001), horizontal coma (P<0.001), and spherical aberration (P<0.001) compared with preoperatively. Postoperatively, 41% exhibited refractive astigmatism of 0.50 diopter (D) or less; 83.8% showed 1.00 D or less. Conclusion: The results of our study indicate that combined simultaneous PRK with CXL can be a safe and effective method for treating refractive instability in KCS patients.
MeSH term(s)	Female ; Humans ; Adult ; Photorefractive Keratectomy/adverse effects ; Photorefractive Keratectomy/methods ; Keratoconus/diagnosis ; Keratoconus/drug therapy ; Keratoconus/surgery ; Visual Acuity ; Photosensitizing Agents/adverse effects ; Retrospective Studies ; Riboflavin/adverse effects ; Corneal Topography ; Corneal Stroma/surgery ; Collagen ; Cross-Linking Reagents/adverse effects
Chemical Substances	Photosensitizing Agents ; Riboflavin (TLM2976OFR) ; Collagen (9007-34-5) ; Cross-Linking Reagents
Language	English
Publishing date	2023-04-19
Publishing country	France
Document type	Journal Article
ZDB-ID	426662-6
ISSN	1773-0597 ; 0181-5512
ISSN (online)	1773-0597
ISSN	0181-5512
DOI	10.1016/j.jfo.2022.11.029
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1417: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Modeling the Protective Role of Bacterial Lipopolysaccharides against Membrane-Rupturing Peptides

Nourbakhsh, Shokoofeh / Yu, Liu / Ha, Bae-Yeun

Journal of physical chemistry. 2021 July 28, v. 125, no. 31

2021

Abstract	Lipopolysaccharide (LPS) is a key surface component of Gram-negative bacteria, populating the outer layer of their outer membrane. A number of experimental studies highlight its protective role against harmful molecules such as antibiotics and antimicrobial peptides (AMPs). In this work, we present a theoretical model for describing the interaction between LPS and cationic antimicrobial peptides, which combines the following two key features. The polysaccharide part is viewed as forming a polymer brush, exerting an osmotic pressure on inclusions such as antimicrobial peptides. The charged groups on LPS (those in lipid A and the two Kdo groups in the inner core) form electrostatic binding sites for cationic AMPs or cations. Using the resulting model, we offer a quantitative picture of how the brush component enhances the protective role of LPS against magainin-like peptides, in the presence of divalent cations such as Mg²⁺. The LPS brush tends to diminish the interfacial binding of the peptides, at the lipid headgroup region, by about 30%. In the presence of 5 mM of Mg²⁺, the interfacial binding does not reach a threshold value for wild-type LPS, beyond which the LPS layer is ruptured, even though it does for LPS Re (the simplest form of LPS, lacking the brush part), as long as [AMP] ≤ 20 μM, where [AMP] is the concentration of AMPs. At a low concentration of Mg²⁺ (≈1 mM), however, a smaller [AMP] value (≳2 μM) is needed to reach the threshold coverage for wild-type LPS. Our results also suggest that the interfacial binding of peptides is insensitive to their possible weak interaction with the surrounding brush chains.
Keywords	antimicrobial peptides ; lipid A ; osmotic pressure ; polymers ; protective effect ; theoretical models
Language	English
Dates of publication	2021-0728
Size	p. 8839-8854.
Publishing place	American Chemical Society
Document type	Article
ISSN	1520-5207
DOI	10.1021/acs.jpcb.1c02330
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: FAPI PET/CT provides higher uptake and better target to back ground in recurrent and metastatic tumors of patients with Iodine refractory papillary thyroid cancer compared with FDG PET CT

Nourbakhsh, Shaghayegh / Salehi, Yalda / Farzanehfar, Saeed / Ghaletaki, Reza / Bakhshi Kashi, Mohsen / Abbasi, Mehrshad

Nuklearmedizin - NuclearMedicine

2024

Abstract	Purpose: The role of fibroblast activation protein inhibitor (FAPI) PET CT scan is not well documented in papillary thyroid cancer (PTC) patients. Patients with radioiodine refractory PTC and high thyroglobulin levels need PET/CT scan which is generally done by 18F FDG. In the current study, the diagnostic performance of 68Ga FAPI and FDG PET/CT scans were compared head to head in patients with radioiodine refractory PTC. Method: Fourteen patients with negative whole body Iodine scans and high thyroglobulin levels underwent whole body PET scans with, respectively, 120–310 and 145–370 MBq 68Ga FAPI-46 and 18F FDG. SUVmax of the back ground in the blood pool and liver and the hottest, largest and average neck, mediastinum, lung and bone lesions were calculated and compared. Result: Ten patients had at least one active (SUVmax>blood pool) lesion similarly in two scans. The liver and blood pool SUVmax values were 1.25(0.2) and 1.7(0.2) in FAPI and 2.65(0.2) and 2.0(0.2) in FDG PET images, respectively. The difference was significant (p=0.001). Standard SUV of the hottest lesion to liver was above 3 in all FAPI scans but in half of FDG scans. Target lesion number and intensity were similar between two PET studies but in a patient out of 5 pulmonary metastatic patients, pulmonary nodules were negative (SUVmax=0.9) in FDG while positive (SUVmax= 3.8) in FAPI images (i.e. 20% patient upstaged). Conclusion: FAPI accumulates in the recurrent and metastatic lesions of patients with Iodine refractory PTC at least as well as FDG with particular privileges as lower injected activity and lower back ground.
Keywords	papillary thyroid cancer ; radioiodine ; PET CT scan ; Fibroblast activation protein
Language	English
Publishing date	2024-01-08
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2030804-8
ISSN	2567-6407 ; 0029-5566
ISSN (online)	2567-6407
ISSN	0029-5566
DOI	10.1055/a-2185-7746
Database	Thieme publisher's database

Order via subito

Article ; Online: Modeling Cell Selectivity of Antimicrobial Peptides: How Is the Selectivity Influenced by Intracellular Peptide Uptake and Cell Density.

Schefter, Bethany R / Nourbakhsh, Shokoofeh / Taheri-Araghi, Sattar / Ha, Bae-Yeun

Frontiers in medical technology

2021 Volume 3, Page(s) 626481

Abstract: Antimicrobial peptides (AMPs) are known to attack bacteria selectively over their host cells. Many attempts have been made to use them as a template for designing peptide antibiotics for fighting drug-resistant bacteria. A central concept in this ... ...

Abstract	Antimicrobial peptides (AMPs) are known to attack bacteria selectively over their host cells. Many attempts have been made to use them as a template for designing peptide antibiotics for fighting drug-resistant bacteria. A central concept in this endeavor is "peptide selectivity," which measures the "quality" of peptides. However, the relevance of selectivity measurements has often been obscured by the cell-density dependence of the selectivity. For instance, the selectivity can be overestimated if the cell density is larger for the host cell. Furthermore, recent experimental studies suggest that peptide trapping in target bacteria magnifies the cell-density dependence of peptide activity. Here, we propose a biophysical model for peptide activity and selectivity, which assists with the correct interpretation of selectivity measurements. The resulting model shows how cell density and peptide trapping in cells influence peptide activity and selectivity: while these effects can alter the selectivity by more than an order of magnitude, peptide trapping works in favor of host cells at high host-cell densities. It can be used to correct selectivity overestimates.
Language	English
Publishing date	2021-02-22
Publishing country	Switzerland
Document type	Journal Article
ISSN	2673-3129
ISSN (online)	2673-3129
DOI	10.3389/fmedt.2021.626481
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- Full text online
- Order with fees

Article: Novel corona discharge treatment of cotton fabric with Cu and ZnO nanoparticles

Nourbakhsh, Shirin / Sepehrnia, Hengameh / Akbari, Eela

The journal of the Textile Institute. 2020 Sept. 1, v. 111, no. 9

2020

Abstract: The aim of this study was to investigate coating of copper and zinc oxide nanoparticles on cotton fabric by using corona discharge in two ways of pre-treatment and post-treatment. In pre-treatment method, cotton fabrics were modified by corona discharge ... ...

Abstract	The aim of this study was to investigate coating of copper and zinc oxide nanoparticles on cotton fabric by using corona discharge in two ways of pre-treatment and post-treatment. In pre-treatment method, cotton fabrics were modified by corona discharge before coating separately with nanoparticles. In post-treatment, cotton fabrics were coated separately with ZnO and Cu nanoparticles before treating by corona discharge. Self-cleaning properties of treated fabrics were determined by staining methylene blue dye. The antibacterial tests, Scanning electron microscopy and FTIR/ATR analysis were carried out to observe antibacterial performance, surface morphology and analyze the surface chemical structure, respectively. Atomic absorption spectroscopy and water droplet adsorption were used for the determination of metal ion content, and water adsorption. Results showed that by pre-treatment method of corona discharge, absorption of copper nanoparticles was increased, and self-cleaning effect and antibacterial performance of copper nanoparticles were higher than post-treatment. ZnO nanoparticles had highest self-cleaning and antibacterial effect by pre-treatment method. By post-treatment method, the photocatalyst activity of ZnO nanoparticles was decreased.
Keywords	absorption ; adsorption ; antibacterial properties ; atomic absorption spectrometry ; chemical structure ; copper ; copper nanoparticles ; cotton ; cotton fabric ; droplets ; methylene blue ; photocatalysts ; zinc oxide
Language	English
Dates of publication	2020-0901
Size	p. 1269-1276.
Publishing place	Taylor & Francis
Document type	Article
Note	NAL-AP-2-clean
ISSN	1754-2340
DOI	10.1080/00405000.2019.1707346
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED