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Article ; Online: Does Experimental Non-Reclaimed Sites Differ from Technically Reclaimed Areas in the Risk of Artificial Bird Nest Predation?

Novák Jakub / Hendrychová Markéta

Journal of Landscape Ecology, Vol 14, Iss 1, Pp 59-

2021 Volume 72

Abstract: Areas left to natural development have been found to be sites with higher diversity and conservation value of local communities, including bird communities, compared to artificial reclamation of post-industrial areas. Most of the studies conducted so far ...

Abstract	Areas left to natural development have been found to be sites with higher diversity and conservation value of local communities, including bird communities, compared to artificial reclamation of post-industrial areas. Most of the studies conducted so far have focused primarily on bird communities of post-mining areas, in terms of the diversity and richness of species. Our study dealt with bird nest predation on specific case of two experimental sites (20 and 32 ha) with more than a 20-year history of primary spontaneous succession established within the technical reclamation of the Radovesická spoil heap (approx. 1,200 ha, North Bohemia, Czech Republic). In the spring of 2018, we conducted a predation experiment using artificial nests (ground and elevated), installed within both succession areas and beyond, in the adjacent artificially reclaimed areas. We monitored the way of restoration and the distance of the nest placement from the succession-reclamation sites edge. The rate of predation was very high: 92.5 % in reclaimed area and 89.4 % in spontaneous successions. None of the observed factors analysed in the generalised linear model (GLM) have conclusively explained the risk of predation. The two experimental succession sites did not differ from the surrounding reclaimed sites in terms of the risk of predation, nor did they significantly influence predation risk on reclaimed sites. We believe that both relatively small and mutually isolated areas do not provide enough of an inner environment without or with at least a limited effect of predation pressure coming from adjacent reclaimed areas.
Keywords	predation risk ; spontaneous development ; technical reclamation ; nest predator ; matrix effect ; Ecology ; QH540-549.5
Subject code	590
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	Sciendo
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Does Experimental Non-Reclaimed Sites Differ from Technically Reclaimed Areas in the Risk of Artificial Bird Nest Predation?

Novák, Jakub / Hendrychová, Markéta

Journal of landscape ecology. 2021 May 01, v. 14, no. 1

A Case Study in Radovesická Spoil Heap

2021

Abstract	Areas left to natural development have been found to be sites with higher diversity and conservation value of local communities, including bird communities, compared to artificial reclamation of post-industrial areas. Most of the studies conducted so far have focused primarily on bird communities of post-mining areas, in terms of the diversity and richness of species. Our study dealt with bird nest predation on specific case of two experimental sites (20 and 32 ha) with more than a 20-year history of primary spontaneous succession established within the technical reclamation of the Radovesická spoil heap (approx. 1,200 ha, North Bohemia, Czech Republic). In the spring of 2018, we conducted a predation experiment using artificial nests (ground and elevated), installed within both succession areas and beyond, in the adjacent artificially reclaimed areas. We monitored the way of restoration and the distance of the nest placement from the succession-reclamation sites edge. The rate of predation was very high: 92.5 % in reclaimed area and 89.4 % in spontaneous successions. None of the observed factors analysed in the generalised linear model (GLM) have conclusively explained the risk of predation. The two experimental succession sites did not differ from the surrounding reclaimed sites in terms of the risk of predation, nor did they significantly influence predation risk on reclaimed sites. We believe that both relatively small and mutually isolated areas do not provide enough of an inner environment without or with at least a limited effect of predation pressure coming from adjacent reclaimed areas.
Keywords	birds ; case studies ; landscape ecology ; linear models ; nests ; predation ; risk ; spring ; Czech Republic
Language	English
Dates of publication	2021-0501
Size	p. 59-72.
Publishing place	Sciendo
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2808692-2
ISSN	1805-4196
ISSN	1805-4196
DOI	10.2478/jlecol-2021-0004
Database	NAL-Catalogue (AGRICOLA)

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Article: Bordetellapertussis Acetylome is Shaped by Lysine Deacetylase Bkd1

Novak, Jakub / Fabrik, Ivo / Jurnecka, David / Holubova, Jana / Stanek, Ondrej / Sebo, Peter

Journal of proteome research. 2020 July 17, v. 19, no. 9

2020

Abstract: Post-translational modifications of proteins enable swift physiological adaptation of cells to altered growth conditions and stress. Aside from protein phosphorylation, acetylation on ε-amino groups of lysine residues (N-ε-lysine acetylation) represents ... ...

Abstract	Post-translational modifications of proteins enable swift physiological adaptation of cells to altered growth conditions and stress. Aside from protein phosphorylation, acetylation on ε-amino groups of lysine residues (N-ε-lysine acetylation) represents another important post-translational modification of proteins. For many bacterial pathogens, including the whooping cough agent Bordetella pertussis, the role and extent of protein acetylation remain to be defined. We expressed in Escherichia coli the BP0960 and BP3063 genes encoding two putative deacetylases of B. pertussis and show that BP0960 encodes a lysine deacetylase enzyme, named Bkd1, that regulates acetylation of a range of B. pertussis proteins. Comparison of the proteome and acetylome of a Δbkd1 mutant with the proteome and acetylome of wild-type B. pertussis (PRIDE ID. PXD016384) revealed that acetylation on lysine residues may modulate activities or stabilities of proteins involved in bacterial metabolism and histone-like proteins. However, increased acetylation of the BvgA response regulator protein of the B. pertussis master virulence-regulating BvgAS two-component system affected neither the total levels of produced BvgA nor its phosphorylation status. Indeed, the Δbkd1 mutant was not impaired in the production of key virulence factors and its survival within human macrophages in vitro was not affected. The Δbkd1 mutant exhibited an increased growth rate under carbon source-limiting conditions and its virulence in the in vivo mouse lung infection model was somewhat affected. These results indicate that the lysine deacetylase Bkd1 and N-ε-lysine acetylation primarily modulate the general metabolism rather than the virulence of B. pertussis.
Keywords	Bordetella pertussis ; Escherichia coli ; acetylation ; carbon ; genes ; histone deacetylase ; humans ; lungs ; lysine ; macrophages ; mice ; models ; mutants ; pathogens ; post-translational modification ; protein phosphorylation ; proteome ; regulatory proteins ; virulence ; whooping cough
Language	English
Dates of publication	2020-0717
Size	p. 3680-3696.
Publishing place	American Chemical Society
Document type	Article
ZDB-ID	2078618-9
ISSN	1535-3907 ; 1535-3893
ISSN (online)	1535-3907
ISSN	1535-3893
DOI	10.1021/acs.jproteome.0c00178
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Article ; Online: Abdominal wall tension increases using Dynamic Neuromuscular Stabilization principles in different postural positions.

Madle, Katerina / Svoboda, Petr / Stribrny, Martin / Novak, Jakub / Kolar, Pavel / Busch, Andrew / Kobesova, Alena / Bitnar, Petr

Musculoskeletal science & practice

2022 Volume 62, Page(s) 102655

Abstract: Background: Intra-abdominal pressure (IAP) is an important mechanism stabilizing the spine and trunk. IAP regulation depends on the coordination of abdominal muscles, diaphragm and pelvic floor muscles.: Objective: To determine the differences in ... ...

Abstract	Background: Intra-abdominal pressure (IAP) is an important mechanism stabilizing the spine and trunk. IAP regulation depends on the coordination of abdominal muscles, diaphragm and pelvic floor muscles. Objective: To determine the differences in abdominal wall tension (AWT) of various postural positions, first without any correction, then after verbal and manual instructions according to Dynamic Neuromuscular Stabilization (DNS) principles. Methods: In a cross-sectional observational study, thirty healthy individuals (mean age = 22.73 ± 1.91 years) were fitted with two Ohmbelt sensors contralaterally above the inguinal ligament and in the upper lumbar triangle. AWT was measured during five postural positions: sitting, supine with legs raised, squat, bear and hang position. First, spontaneous AWT was measured, then again after manual and verbal instructions following DNS principles. Results: AWT increased significantly with DNS instructions compared to spontaneous activation. Both sensors recorded significant increases (p < .01; Cohen's d = -1.13 to -2.06) in all observed postural situations. The increase in activity occurred simultaneously on both sensors, with no significant differences noted in pressure increases between the sensors. The greatest activation for both sensors occurred in the bear position. Significant increases in activity were identified for both sensors in the supine leg raise position and in the bear position compared to spontaneous activation in sitting (p < .001). There were no statistically significant differences (for both sensors) between women and men in any position. Conclusion: The amount of AWT significantly increases after verbal and manual instructions according to DNS. The greatest abdominal wall activation was achieved in the bear position.
Language	English
Publishing date	2022-08-14
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2888772-4
ISSN	2468-7812
ISSN (online)	2468-7812
DOI	10.1016/j.msksp.2022.102655
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Article ; Online: Bordetella

Novak, Jakub / Fabrik, Ivo / Jurnecka, David / Holubova, Jana / Stanek, Ondrej / Sebo, Peter

Journal of proteome research

2020 Volume 19, Issue 9, Page(s) 3680–3696

Abstract	Post-translational modifications of proteins enable swift physiological adaptation of cells to altered growth conditions and stress. Aside from protein phosphorylation, acetylation on ε-amino groups of lysine residues (
MeSH term(s)	Acetylation ; Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Bordetella pertussis/genetics ; Gene Expression Regulation, Bacterial ; Lysine/metabolism ; Mice ; Virulence
Chemical Substances	Bacterial Proteins ; Lysine (K3Z4F929H6)
Language	English
Publishing date	2020-07-31
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2078618-9
ISSN	1535-3907 ; 1535-3893
ISSN (online)	1535-3907
ISSN	1535-3893
DOI	10.1021/acs.jproteome.0c00178
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Book ; Online ; Thesis: Martin Walsers doppelte Buchführung

Novák, Jakub

die Konstruktion und die Dekonstruktion der nationalen Identität in seinem Spätwerk

2003

Author's details	vorgelegt von Jakub Novák
Keywords	Roman ; Nationalbewusstsein ; Dekonstruktion
Language	German
Size	Online-Ressource
Document type	Book ; Online ; Thesis
Thesis / German Habilitation thesis	Univ., Diss--Konstanz, 2002
Database	Former special subject collection: coastal and deep sea fishing

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Article ; Online: Anorectal dysfunction in multiple sclerosis patients: A pilot study on the effect of an individualized rehabilitation approach.

Kovari, Martina / Stovicek, Jan / Novak, Jakub / Havlickova, Michaela / Mala, Sarka / Busch, Andrew / Kolar, Pavel / Kobesova, Alena

NeuroRehabilitation

2021 Volume 50, Issue 1, Page(s) 89–99

Abstract: Background: Anorectal dysfunction (ARD), especially bowel incontinence, frequently compromises the quality of life in multiple sclerosis (MS) patients. The effect of rehabilitation procedures has not been clearly established.: Objective: To determine ...

Abstract	Background: Anorectal dysfunction (ARD), especially bowel incontinence, frequently compromises the quality of life in multiple sclerosis (MS) patients. The effect of rehabilitation procedures has not been clearly established. Objective: To determine the effect of an individualized rehabilitation approach on bowel incontinence and anorectal pressures. Methods: MS patients with ARD underwent 6-months of individually targeted biofeedback rehabilitation. High resolution anorectal manometry (HRAM) and St. Mark's Fecal Incontinence Scores (SMIS) were completed prior to rehabilitation, after 10 weeks of supervised physiotherapy, and after 3 months of self-treatment. Results: Ten patients (50%) completed the study. Repeated measures analysis of variance (ANOVA) demonstrated significant improvement in the SMIS questionnaire over time [14.00 baseline vs. 9.70 after supervised physiotherapy vs. 9.30 after self-treatment (p = 0.005)]. No significant improvements over time were noted in any HRAM readings: maximal pressure [49.85 mmHg baseline vs. 57.60 after supervised physiotherapy vs. 60.88 after self-treatment (p = 0.58)], pressure endurance [36.41 vs. 46.89 vs. 49.95 (p = 0.53)], resting pressure [55.83, vs 52.69 vs. 51.84 (p = 0.704)], or area under the curve [230.0 vs. 520.8 vs. 501.9 (p = 0.16)]. Conclusions: The proposed individualized rehabilitation program supports a positive overall effect on anorectal dysfunction in MS patients.
MeSH term(s)	Biofeedback, Psychology ; Fecal Incontinence/etiology ; Humans ; Manometry ; Multiple Sclerosis/complications ; Pilot Projects ; Quality of Life
Language	English
Publishing date	2021-10-22
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1087912-2
ISSN	1878-6448 ; 1053-8135
ISSN (online)	1878-6448
ISSN	1053-8135
DOI	10.3233/NRE-210226
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Article ; Online: Intra-abdominal pressure correlates with abdominal wall tension during clinical evaluation tests.

Novak, Jakub / Jacisko, Jakub / Busch, Andrew / Cerny, Pavel / Stribrny, Martin / Kovari, Martina / Podskalska, Patricie / Kolar, Pavel / Kobesova, Alena

Clinical biomechanics (Bristol, Avon)

2021 Volume 88, Page(s) 105426

Abstract: Background: The abdominal muscles play an important respiratory and stabilization role, and in coordination with other muscles regulate the intra-abdominal pressure stabilizing the spine. The evaluation of postural trunk muscle function is critical in ... ...

Abstract	Background: The abdominal muscles play an important respiratory and stabilization role, and in coordination with other muscles regulate the intra-abdominal pressure stabilizing the spine. The evaluation of postural trunk muscle function is critical in clinical assessments of patients with musculoskeletal pain and dysfunction. This study evaluates the relationship between intra-abdominal pressure measured as anorectal pressure with objective abdominal wall tension recorded by mechanical-pneumatic-electronic sensors. Methods: In a cross-sectional observational study, thirty-one asymptomatic participants (mean age = 26.77 ± 3.01 years) underwent testing to measure intra-abdominal pressure via anorectal manometry, along with abdominal wall tension measured by sensors attached to a trunk brace (DNS Brace). They were evaluated in five different standing postural-respiratory situations: resting breathing, Valsalva maneuver, Müller's maneuver, instructed breathing, loaded breathing when holding a dumbbell. Findings: Strong correlations were demonstrated between anorectal manometry and DNS Brace measurements in all scenarios; and DNS Brace values significantly predicted intra-abdominal pressure values for all scenarios: resting breathing (r = 0.735, r Interpretation: Intra-abdominal pressure is strongly correlated with, and predicted by abdominal wall tension monitored above the inguinal ligament and in the area of superior trigonum lumbale. This study demonstrates that intra-abdominal pressure can be evaluated indirectly by monitoring the abdominal wall tension.
MeSH term(s)	Abdominal Muscles ; Abdominal Wall ; Adult ; Cross-Sectional Studies ; Electromyography ; Humans ; Pressure ; Young Adult
Language	English
Publishing date	2021-07-14
Publishing country	England
Document type	Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	632747-3
ISSN	1879-1271 ; 0268-0033
ISSN (online)	1879-1271
ISSN	0268-0033
DOI	10.1016/j.clinbiomech.2021.105426
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Article: Impact of meteorological and environmental factors on the spatial distribution of Fasciola hepatica in beef cattle herds in Sweden

Novobilský, Adam / Novák, Jakub / Björkman, Camilla / Höglund, Johan

BMC veterinary research. 2015 Dec., v. 11, no. 1

2015

Abstract: BACKGROUND: Fasciola hepatica is a parasite with a significant impact on ruminant livestock production. Previous studies in north-west Europe have described its geographical distribution and determined potential predictors of fasciolosis using ... ...

Abstract	BACKGROUND: Fasciola hepatica is a parasite with a significant impact on ruminant livestock production. Previous studies in north-west Europe have described its geographical distribution and determined potential predictors of fasciolosis using geographical information system (GIS) and regression modelling. In Sweden, however, information about the distribution of fasciolosis is limited. This study examined the geographical distribution of F. hepatica and identified high-risk areas for beef cattle in Sweden and sought to characterise potential predictors. Beef cattle serum samples were collected during winter 2006-2007 from 2135 herds which were examined for F. hepatica antibodies by enzyme-linked immunosorbent assay (ELISA). Fasciolosis distribution maps were created using GIS based on postcode location of seropositive herds. Spatial scan analysis (SaTScan) was performed to determine high-risk areas. Using datasets on animal density, temperature, precipitation and Corine land cover data, including soil type and soil mineral concentrations in Sweden, bivariate and multiple logistic regression analyses were carried out in R software to reveal potential predictors of F. hepatica infection. RESULTS: Overall herd seroprevalence of F. hepatica in beef cattle was 9.8 % (95 % CI: 8.6-11.1). An irregular spatial distribution of F. hepatica, with two main clusters, was observed in south-west Sweden. The most northerly occurrence of F. hepatica in the world was documented. The final model explained 15.8 % of the variation in F. hepatica distribution in study herds. Absence of coniferous forest was the variable with the highest predictive value. Precipitation in July-September, Dystric Cambisol, Dystric Regosol, and P and Cu concentrations in soil were other negative predictors. Beef cattle herd density, Dystric Leptosol and Fe concentration were positive predictors. CONCLUSIONS: The spatial distribution of F. hepatica in Swedish beef cattle herds is influenced by multi-factorial effects. Interestingly, absence of coniferous forest, herd density, specific soil type and concentration of some soil minerals are more important predictors than climate factors.
Keywords	Cambisols ; Fasciola hepatica ; Leptosols ; Regosols ; antibodies ; beef cattle ; blood serum ; climatic factors ; computer software ; coniferous forests ; copper ; data collection ; enzyme-linked immunosorbent assay ; fascioliasis ; geographic information systems ; geographical distribution ; herds ; iron ; land cover ; livestock production ; models ; parasites ; regression analysis ; seroprevalence ; soil minerals ; temperature ; Sweden
Language	English
Dates of publication	2015-12
Size	p. 447.
Publishing place	Springer-Verlag
Document type	Article
ISSN	1746-6148
DOI	10.1186/s12917-015-0447-0
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Article ; Online: Impact of meteorological and environmental factors on the spatial distribution of Fasciola hepatica in beef cattle herds in Sweden.

Novobilský, Adam / Novák, Jakub / Björkman, Camilla / Höglund, Johan

BMC veterinary research

2015 Volume 11, Page(s) 128

Abstract: Background: Fasciola hepatica is a parasite with a significant impact on ruminant livestock production. Previous studies in north-west Europe have described its geographical distribution and determined potential predictors of fasciolosis using ... ...

Abstract	Background: Fasciola hepatica is a parasite with a significant impact on ruminant livestock production. Previous studies in north-west Europe have described its geographical distribution and determined potential predictors of fasciolosis using geographical information system (GIS) and regression modelling. In Sweden, however, information about the distribution of fasciolosis is limited. This study examined the geographical distribution of F. hepatica and identified high-risk areas for beef cattle in Sweden and sought to characterise potential predictors. Beef cattle serum samples were collected during winter 2006-2007 from 2135 herds which were examined for F. hepatica antibodies by enzyme-linked immunosorbent assay (ELISA). Fasciolosis distribution maps were created using GIS based on postcode location of seropositive herds. Spatial scan analysis (SaTScan) was performed to determine high-risk areas. Using datasets on animal density, temperature, precipitation and Corine land cover data, including soil type and soil mineral concentrations in Sweden, bivariate and multiple logistic regression analyses were carried out in R software to reveal potential predictors of F. hepatica infection. Results: Overall herd seroprevalence of F. hepatica in beef cattle was 9.8 % (95 % CI: 8.6-11.1). An irregular spatial distribution of F. hepatica, with two main clusters, was observed in south-west Sweden. The most northerly occurrence of F. hepatica in the world was documented. The final model explained 15.8 % of the variation in F. hepatica distribution in study herds. Absence of coniferous forest was the variable with the highest predictive value. Precipitation in July-September, Dystric Cambisol, Dystric Regosol, and P and Cu concentrations in soil were other negative predictors. Beef cattle herd density, Dystric Leptosol and Fe concentration were positive predictors. Conclusions: The spatial distribution of F. hepatica in Swedish beef cattle herds is influenced by multi-factorial effects. Interestingly, absence of coniferous forest, herd density, specific soil type and concentration of some soil minerals are more important predictors than climate factors.
MeSH term(s)	Animals ; Cattle ; Cattle Diseases/epidemiology ; Cattle Diseases/parasitology ; Environment ; Fascioliasis/epidemiology ; Fascioliasis/veterinary ; Sweden/epidemiology ; Weather
Language	English
Publishing date	2015-06-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1746-6148
ISSN (online)	1746-6148
DOI	10.1186/s12917-015-0447-0
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