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  1. Book: Auftreten des Usutu-Virus in Österreich

    Nowotny, Norbert / Weissenboeck, Herbert

    Erforschung des Usutu-Virus und seiner Bedeutung für Mensch und Tier ; Forschungsberichte der Sektion IV

    (Forschungsberichte der Sektion IV / Bundesministerium für Gesundheit und Frauen, Sektion IV ; 2004,3)

    2004  

    Author's details [Autoren: Norbert Nowotny ; Herbert Weissenböck]. Bundesministerium für Gesundheit und Frauen, BMGF. [Hrsg.: Bundesministerium für Gesundheit und Frauen, Sektion IV. Für den Inhalt verantw.: Harald Gaugg]
    Series title Forschungsberichte der Sektion IV / Bundesministerium für Gesundheit und Frauen, Sektion IV ; 2004,3
    Forschungsberichte der Sektion IV
    Collection Forschungsberichte der Sektion IV
    Language German ; English
    Size 77 S., Ill., graph. Darst., 30 cm
    Publisher BMGF, Sekt. IV
    Publishing place Wien
    Publishing country Austria
    Document type Book
    Note Text teilw. dt., teilw. engl. - Literaturangaben
    HBZ-ID HT014044228
    ISBN 3-900019-12-6 ; 978-3-900019-12-9
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: The knowns and unknowns of West Nile virus in Europe: what did we learn from the 2018 outbreak?

    Camp, Jeremy V / Nowotny, Norbert

    Expert review of anti-infective therapy

    2020  Volume 18, Issue 2, Page(s) 145–154

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Animals ; Disease Outbreaks ; Europe/epidemiology ; Humans ; Mosquito Vectors ; Seasons ; Temperature ; West Nile Fever/epidemiology ; West Nile Fever/transmission ; West Nile virus/isolation & purification
    Language English
    Publishing date 2020-01-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2020.1713751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Monitoring Urban Zoonotic Virus Activity: Are City Rats a Promising Surveillance Tool for Emerging Viruses?

    Camp, Jeremy V / Desvars-Larrive, Amélie / Nowotny, Norbert / Walzer, Chris

    Viruses

    2022  Volume 14, Issue 7

    Abstract: Urban environments represent unique ecosystems where dense human populations may come into contact with wildlife species, some of which are established or potential reservoirs for zoonotic pathogens that cause human diseases. Finding practical ways to ... ...

    Abstract Urban environments represent unique ecosystems where dense human populations may come into contact with wildlife species, some of which are established or potential reservoirs for zoonotic pathogens that cause human diseases. Finding practical ways to monitor the presence and/or abundance of zoonotic pathogens is important to estimate the risk of spillover to humans in cities. As brown rats (
    MeSH term(s) Animals ; Cities/epidemiology ; Ecosystem ; Humans ; Rats ; Rodent Diseases/epidemiology ; Viruses/genetics ; Zoonoses/epidemiology
    Language English
    Publishing date 2022-07-11
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14071516
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Rustrela Virus-Associated Encephalomyelitis ('Staggering Disease') in Cats from Eastern Austria, 1994-2016.

    Weiss, Viktoria / Weidinger, Pia / Matt, Julia / Weissenbacher-Lang, Christiane / Nowotny, Norbert / Weissenböck, Herbert

    Viruses

    2023  Volume 15, Issue 8

    Abstract: Clinical cases of 'staggering disease', a nonsuppurative encephalomyelitis associated with gait abnormalities in cats, have been documented for decades in Sweden. In Austria, an increased incidence was observed in the 1990s. Only recently, rustrela virus ...

    Abstract Clinical cases of 'staggering disease', a nonsuppurative encephalomyelitis associated with gait abnormalities in cats, have been documented for decades in Sweden. In Austria, an increased incidence was observed in the 1990s. Only recently, rustrela virus (RusV) was identified as the causative agent of this clinicopathologic disease entity. In this retrospective study, we analyzed a total of 23 brain and spinal cord samples from Austrian cats with the pathohistological diagnosis of nonsuppurative encephalomyelitis and clinical signs consistent with staggering disease from 1994 to 2016 using reverse transcription real-time polymerase chain reaction (RT-qPCR) and in situ hybridization. We were able to detect RusV nucleic acids in seven of the examined samples. Borna disease virus 1 (BoDV-1) could be excluded in all cases via immunohistochemistry and RT-qPCR. This study confirms that RusV has been a relevant etiological agent of nonsuppurative encephalomyelitis of cats in a geographically and temporally limited disease cluster in Austria, mainly in the 1990s. The geographic distribution of the positive samples in this study is consistent with earlier reports on 'staggering disease' in Austria. Further studies are necessary to confirm the reservoir host of 'staggering disease' in Austria, as well as investigations on the disappearance of this disease and its possible zoonotic potential.
    MeSH term(s) Cats ; Animals ; Austria/epidemiology ; Retrospective Studies ; Brain ; Spinal Cord ; Encephalomyelitis
    Language English
    Publishing date 2023-07-25
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15081621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: African Swine Fever, the forgotten pandemic.

    Ward, Michael P / Tian, Kegong / Nowotny, Norbert

    Transboundary and emerging diseases

    2021  Volume 68, Issue 5, Page(s) 2637–2639

    MeSH term(s) African Swine Fever/epidemiology ; African Swine Fever Virus ; Animals ; Pandemics ; Swine ; Swine Diseases/epidemiology ; Viral Proteins
    Chemical Substances Viral Proteins
    Language English
    Publishing date 2021-09-09
    Publishing country Germany
    Document type Editorial
    ZDB-ID 2414822-2
    ISSN 1865-1682 ; 1865-1674
    ISSN (online) 1865-1682
    ISSN 1865-1674
    DOI 10.1111/tbed.14245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Monitoring Urban Zoonotic Virus Activity: Are City Rats a Promising Surveillance Tool for Emerging Viruses?

    Camp, Jeremy V. / Desvars-Larrive, Amélie / Nowotny, Norbert / Walzer, Chris

    Viruses. 2022 July 11, v. 14, no. 7

    2022  

    Abstract: Urban environments represent unique ecosystems where dense human populations may come into contact with wildlife species, some of which are established or potential reservoirs for zoonotic pathogens that cause human diseases. Finding practical ways to ... ...

    Abstract Urban environments represent unique ecosystems where dense human populations may come into contact with wildlife species, some of which are established or potential reservoirs for zoonotic pathogens that cause human diseases. Finding practical ways to monitor the presence and/or abundance of zoonotic pathogens is important to estimate the risk of spillover to humans in cities. As brown rats (Rattus norvegicus) are ubiquitous in urban habitats, and are hosts of several zoonotic viruses, we conducted longitudinal sampling of brown rats in Vienna, Austria, a large population center in Central Europe. We investigated rat tissues for the presence of several zoonotic viruses, including flaviviruses, hantaviruses, coronaviruses, poxviruses, hepatitis E virus, encephalomyocarditis virus, and influenza A virus. Although we found no evidence of active infections (all were negative for viral nucleic acids) among 96 rats captured between 2016 and 2018, our study supports the findings of others, suggesting that monitoring urban rats may be an efficient way to estimate the activity of zoonotic viruses in urban environments.
    Keywords Cardiovirus A ; Flaviviridae ; Influenza A virus ; Orthocoronavirinae ; Orthohantavirus ; Orthohepevirus A ; Poxviridae ; Rattus norvegicus ; humans ; monitoring ; rats ; risk assessment ; viruses ; wildlife ; Austria ; Central European region
    Language English
    Dates of publication 2022-0711
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2516098-9
    ISSN 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14071516
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: MERS-Coronavirus von Kamel auf Mensch übertragbar

    Nowotny, Norbert

    Hygiene & Medizin

    2014  Volume 39, Issue 5, Page(s) 168

    Language German
    Document type Article
    ZDB-ID 518696-1
    ISSN 0172-3790
    ISSN 0172-3790
    Database bibnet.org

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  8. Article ; Online: Severe Neurologic Disease in a Horse Caused by Tick-Borne Encephalitis Virus, Austria, 2021.

    de Heus, Phebe / Bagó, Zoltán / Weidinger, Pia / Lale, Dilara / Trachsel, Dagmar S / Revilla-Fernández, Sandra / Matiasek, Kaspar / Nowotny, Norbert

    Viruses

    2023  Volume 15, Issue 10

    Abstract: As evidenced by sero-epidemiological studies, infections of horses with the tick-borne encephalitis virus (TBEV) occur frequently in TBEV-endemic areas. However, there are only very few reports of clinical cases. A possible underreporting may be due to a ...

    Abstract As evidenced by sero-epidemiological studies, infections of horses with the tick-borne encephalitis virus (TBEV) occur frequently in TBEV-endemic areas. However, there are only very few reports of clinical cases. A possible underreporting may be due to a variety of diagnostic challenges. In this study, ELISA and neutralization tests were applied to serum samples. Brain tissue samples were investigated for the presence of nucleic acids of TBEV,
    MeSH term(s) Animals ; Horses ; Encephalitis Viruses, Tick-Borne/genetics ; Encephalitis, Tick-Borne/diagnosis ; Encephalitis, Tick-Borne/epidemiology ; Encephalitis, Tick-Borne/veterinary ; Austria/epidemiology ; Antibodies, Viral ; Nucleic Acids
    Chemical Substances Antibodies, Viral ; Nucleic Acids
    Language English
    Publishing date 2023-09-29
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15102022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Peptidomic analysis of the host-defense peptides in skin secretions of the Amazon River frog Lithobates palmipes (Ranidae).

    Mechkarska, Milena / Barran, Gervonne / Kolodziejek, Jolanta / Coquet, Laurent / Leprince, Jérôme / Jouenne, Thierry / Nowotny, Norbert / Conlon, J Michael

    Comparative biochemistry and physiology. Part D, Genomics & proteomics

    2023  Volume 46, Page(s) 101069

    Abstract: Skin secretions of certain frog species represent a source of host-defense peptides (HDPs) with therapeutic potential and their primary structures provide insight into taxonomic and phylogenetic relationships. Peptidomic analysis was used to characterize ...

    Abstract Skin secretions of certain frog species represent a source of host-defense peptides (HDPs) with therapeutic potential and their primary structures provide insight into taxonomic and phylogenetic relationships. Peptidomic analysis was used to characterize the HDPs in norepinephrine-stimulated skin secretions from the Amazon River frog Lithobates palmipes (Ranidae) collected in Trinidad. A total of ten peptides were purified and identified on the basis of amino acid similarity as belonging to the ranatuerin-2 family (ranatuerin-2PMa, -2PMb, -2PMc, and-2PMd), the brevinin-1 family (brevinin-1PMa, -1PMb, -1PMc and des(8-14)brevinin-1PMa) and the temporin family (temporin-PMa in C-terminally amidated and non-amidated forms). Deletion of the sequence VAAKVLP from brevinin-1PMa (FLPLIAGVAAKVLPKIFCAISKKC) in des[(8-14)brevinin-1PMa resulted in a 10-fold decrease in potency against Staphylococcus aureus (MIC = 31 μM compared with 3 μM) and a > 50-fold decrease in hemolytic activity but potency against Echerichia coli was maintained (MIC = 62.5 μM compared with 50 μM). Temporin-PMa (FLPFLGKLLSGIF.NH
    MeSH term(s) Animals ; Amino Acid Sequence ; Phylogeny ; Staphylococcus aureus/metabolism ; Ranidae/metabolism ; Amphibian Proteins/metabolism ; Skin/metabolism
    Chemical Substances Amphibian Proteins
    Language English
    Publishing date 2023-02-24
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2212119-5
    ISSN 1878-0407 ; 1744-117X
    ISSN (online) 1878-0407
    ISSN 1744-117X
    DOI 10.1016/j.cbd.2023.101069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Thesis: MODULATION DER TUMORENTWICKLUNG DURCH GLEICHZEITIGE INFEKTION MIT HERPES-SIMPLEX-VIRUS TYP-1 [TYP EINS] UND TYP-2 [TYP ZWEI]

    Nowotny, Norbert

    STIMULIERTE, UNBEEINFLUSSTE SOWIE VERZOEGERTE TUMORENTWICKLUNG

    (DISSERTATIONEN DER UNIVERSITAET WIEN ; 153)

    1982  

    Title variant MODULATION DER TUMORENTWICKLUNG DURCH GLEICHZEITIGE INFEKTION MIT HERPES-SIMPLEX-VIRUS TYP-1 UND TYP-2
    Series title DISSERTATIONEN DER UNIVERSITAET WIEN ; 153
    Dissertationen der Universität Wien
    Collection Dissertationen der Universität Wien
    Keywords GROWTH FACTORS ; HERPES SIMPLEX / COMPLICATIONS ; NEOPLASMS / COMPLICATIONS ; Lewis-Lung-Carcinom ; Lewis-Lung-Krebs ; Maus ; Herpes-simplex-Virus ; Carcinogenese
    Subject Krebs ; Krebsentstehung ; Karzinogenese ; Kanzerogenese ; Onkogenese ; HSV ; A-Virus ; Hepesvirus hominis ; Labormaus ; Weiße Maus ; Lewis Lung Carcinoma ; Lewis-Lung-Krebs
    Size 276 S. : ILL., GRAPH. DARST.
    Publisher VWGOE
    Publishing place WIEN
    Publishing country Austria
    Document type Book ; Thesis
    Thesis / German Habilitation thesis WIEN, UNIV., DISS., 1981
    HBZ-ID HT002470184
    ISBN 3-85369-506-X ; 978-3-85369-506-7
    Database Catalogue ZB MED Medicine, Health

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