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  1. Book: Free communications / Vulval Pain Syndrome Study Day

    Nunns, D.

    Derby, 5 March 1999

    1999  

    Institution Vulval Pain Syndrome Study Day
    Author's details ed. by D. Nunns
    Language English
    Publishing country Great Britain
    Document type Book
    Note Enth. Abstracts ; In: Journal of obstetrics and gynaecology. - ISSN 0144-3615. - 19 (1999),5, S. 566 - 568
    HBZ-ID HT011117216
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Is routine gastrointestinal endoscopy required in every woman with mucinous ovarian cancer? An analysis of survival rates and metastatic tumours in a cancer centre.

    Katsanevakis, E / Addo-Yobo, W / Bharathan, B / Loona, A / Gan, C / Nunns, D / Gajjar, K

    European journal of obstetrics, gynecology, and reproductive biology

    2024  Volume 294, Page(s) 105–110

    Abstract: Introduction: Mucinous ovarian cancer (MOC) represents a rare entity of ovarian malignant neoplasms. The true incidence could be as low as 3% of all ovarian cancers. The aim of this study is to compare and understand the clinicopathological ... ...

    Abstract Introduction: Mucinous ovarian cancer (MOC) represents a rare entity of ovarian malignant neoplasms. The true incidence could be as low as 3% of all ovarian cancers. The aim of this study is to compare and understand the clinicopathological characteristics of patients with mucinous ovarian cancer, report on the survival rates and evaluate the role of gastrointestinal (GI) endoscopy as part of the peri-operative investigations and the impact it has on the survival rates.
    Methodology: This is a retrospective data collection on patients with MOC operated in Nottingham gynaecological oncology centre over a 10-year period. Data were analysed using SPSS software.
    Results: 43 cases were included in the final analysis. The median maximal tumour diameter was 180 mm. 32 (74.5 %) and 11 (25.5 %) women presented with unilateral and bilateral tumours respectively. 30 patients (69.7 %) presented with stage 1 disease, 1 (2.3 %) presented with stage 2 disease, 7 women (16.4 %) had stage 3 disease and 1 woman (11.6 %) had stage 4 disease. 41 women had staging surgical procedures and 2 women had limited surgery due to poor performance status. After final histology, 5 cases found to have metastatic disease to the ovary rather than primary MOC. 14 women had GI endoscopy as part of their investigation. The total estimated cost of the endoscopies that have been performed is £5635. Primary GI cancer was diagnosed in 1 case during the endoscopy (1 case of gastric cancer). The 5-year overall survival of the women included in this study is 62.8 %. The 5-year overall survival of the women in the endoscopy and non-endoscopy groups was 60 % and 64.3 % respectively (p-value: 0.767).
    Conclusion: The findings of this study show that the survival rates of patients treated for mucinous ovarian cancer in our centre are similar to other published studies. Our findings do not support the routine use of GI endoscopy in the peri-operative investigations of every patient with MOC due to the non-statistically significant difference in the overall survival.
    MeSH term(s) Humans ; Female ; Male ; Retrospective Studies ; Survival Rate ; Carcinoma, Ovarian Epithelial/pathology ; Ovarian Neoplasms/pathology ; Adenocarcinoma, Mucinous/pathology ; Endoscopy, Gastrointestinal ; Neoplasm Staging
    Language English
    Publishing date 2024-01-14
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2024.01.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Working with UK-based non-governmental organisations for better reproductive health in Nepal.

    Nunns, D

    BJOG : an international journal of obstetrics and gynaecology

    2011  Volume 118 Suppl 2, Page(s) 93–95

    Abstract: Over the years, strong health links have developed between Nepal and the UK with the overall aim of helping to achieve Millennium Development Goals 4 and 5. The nature of such health links is varied and ranges from education and training projects to ... ...

    Abstract Over the years, strong health links have developed between Nepal and the UK with the overall aim of helping to achieve Millennium Development Goals 4 and 5. The nature of such health links is varied and ranges from education and training projects to service work, with a focus on direct medical care. The role of non-governmental organisations (NGOs) in Nepal cannot be underestimated: there are over 5000 NGOs, working in all aspects of Nepali life. Most are not specifically dedicated to maternal, neonatal and reproductive health care, but have developed this area of interest in response to the identified needs in the local communities. The benefits from such health links are immense but, in times of limited funding of projects, it is increasingly important that different agencies work together to maximise the impact of projects.
    MeSH term(s) Delivery of Health Care/organization & administration ; Developing Countries ; Female ; Humans ; Maternal Health Services/organization & administration ; Nepal ; Organizational Objectives ; Organizations, Nonprofit ; Pregnancy ; Societies, Medical ; United Kingdom ; United Nations/standards
    Language English
    Publishing date 2011-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2000931-8
    ISSN 1471-0528 ; 0306-5456 ; 1470-0328
    ISSN (online) 1471-0528
    ISSN 0306-5456 ; 1470-0328
    DOI 10.1111/j.1471-0528.2011.03117.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tackling vulvodynia.

    Nunns, D

    The British journal of dermatology

    2011  Volume 164, Issue 3, Page(s) 464

    MeSH term(s) Female ; Humans ; Pain/etiology ; Pain Management ; Vulvodynia/diagnosis ; Vulvodynia/therapy
    Language English
    Publishing date 2011-03
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/j.1365-2133.2011.10259.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Vulval extra-mammary Paget's disease: the master of disguise revealed.

    O'Neill, Danielle / Evans, Matthew / Nunns, David / El-Ghobashy, Alaa

    British journal of hospital medicine (London, England : 2005)

    2022  Volume 83, Issue 2, Page(s) 1–12

    Abstract: Extra-mammary Paget's disease is a rare cancer affecting the anogenital region and can present with a myriad of symptoms. In women, the diagnosis of Paget's disease can be challenging as it mimics several other vulval conditions. It is important to ... ...

    Abstract Extra-mammary Paget's disease is a rare cancer affecting the anogenital region and can present with a myriad of symptoms. In women, the diagnosis of Paget's disease can be challenging as it mimics several other vulval conditions. It is important to promptly recognise this disease because of its potential association with synchronous tumours, such as colorectal adenocarcinoma. The mainstay of treatment is with immunomodulating therapies or surgery, but unfortunately the risk of recurrence is high and appears to be independent of treatment choice and tissue margin status. There is growing evidence to move away from traditional surgical excision to using topical therapy, such as imiquimod, as surgery can often be extensive and disfiguring with a prolonged recovery time. There is considerable psychosexual and physical morbidity associated with Paget's disease, largely owing to multiple surgical recurrences. As recurrences can occur several years after the initial presentation, long-term follow up of patients is recommended.
    MeSH term(s) Adenocarcinoma/pathology ; Female ; Humans ; Paget Disease, Extramammary/diagnosis ; Paget Disease, Extramammary/surgery
    Language English
    Publishing date 2022-02-10
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1750-8460
    ISSN 1750-8460
    DOI 10.12968/hmed.2021.0536
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A study of recurrence, complication and survival rates in patients with early stage vulval cancer undergoing sentinel lymph node sampling: a single-centre experience.

    Katsanevakis, Emmanouil / Joshi, Anuja / Ong, Zun Zhen / O'Connor, Richard / Nunns, David / Gajjar, Ketankumar

    Archives of gynecology and obstetrics

    2023  Volume 308, Issue 2, Page(s) 561–567

    Abstract: Purpose: Groin sentinel lymph node (SLN) identification and removal has become a standard of care for women with clinical early stage vulval cancer. There is evidence to support safe detection of the SLN with minimal morbidity. The purpose of this study ...

    Abstract Purpose: Groin sentinel lymph node (SLN) identification and removal has become a standard of care for women with clinical early stage vulval cancer. There is evidence to support safe detection of the SLN with minimal morbidity. The purpose of this study is to report our experience of managing patients focusing on patient selection, adverse events, quality assurance of the procedure and any benefits and/or disadvantages to patients.
    Methods: This was a retrospective study of patients with clinical early stage vulval cancer in a cancer centre over 5 years. Notes and hospital data were reviewed including admissions to emergency departments. Statistical software was used for the statistical analysis and the Kaplan Meier survival curve was generated to present survival rates.
    Results: 61 cases were analysed. A total of 156 nodes have been removed and positive nodes were identified in 14 cases. In total, 9 women (14.75%) had disease recurrence within 5 years from primary surgery. Overall, 4 patients (6.5%) developed groin recurrence. In 3 of these patients there was isolated groin recurrence (4.9%). The median length of admission was 3 days and 6 cases were managed as day cases.
    Conclusions: Since the closure of the GROINNS-2 trial we have continued the procedure of SLN identification for women with clinical early stage vulval cancer. We have shown high level of adherence to our protocol and survival and complication rates comparable to other studies on the same field. There were a few patients managed as day-case which was of benefit to the patients.
    MeSH term(s) Humans ; Female ; Sentinel Lymph Node/surgery ; Sentinel Lymph Node/pathology ; Sentinel Lymph Node Biopsy/adverse effects ; Sentinel Lymph Node Biopsy/methods ; Lymph Node Excision/methods ; Lymphatic Metastasis/pathology ; Retrospective Studies ; Survival Rate ; Vulvar Neoplasms/surgery ; Vulvar Neoplasms/pathology ; Neoplasm Recurrence, Local/pathology ; Lymph Nodes/surgery ; Lymph Nodes/pathology
    Language English
    Publishing date 2023-02-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-023-06968-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Vulval pain syndromes.

    Nunns, D

    BJOG : an international journal of obstetrics and gynaecology

    2000  Volume 107, Issue 10, Page(s) 1185–1193

    MeSH term(s) Female ; Humans ; Pain/etiology ; Pain Management ; Somatosensory Disorders/diagnosis ; Somatosensory Disorders/etiology ; Somatosensory Disorders/therapy ; Vulvar Diseases/diagnosis ; Vulvar Diseases/etiology ; Vulvar Diseases/therapy
    Language English
    Publishing date 2000-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2000931-8
    ISSN 1471-0528 ; 1470-0328 ; 0306-5456
    ISSN (online) 1471-0528
    ISSN 1470-0328 ; 0306-5456
    DOI 10.1111/j.1471-0528.2000.tb11606.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A national audit of standards of care for women with vulval conditions and survey of attitudes to nurse practitioners in vulval services in the UK.

    Innamaa, A / Tidy, J A / Nunns, D / Palmer, J E

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

    2016  Volume 36, Issue 3, Page(s) 380–385

    Abstract: This national audit assessed whether UK specialist vulval clinics adhere to the British Society of Vulval Diseases (BSSVD) document 'Standards of care for women with vulval conditions' published in 2013 and benchmarked clinician attitudes towards nurse ... ...

    Abstract This national audit assessed whether UK specialist vulval clinics adhere to the British Society of Vulval Diseases (BSSVD) document 'Standards of care for women with vulval conditions' published in 2013 and benchmarked clinician attitudes towards nurse practitioners in vulval services. Audit standards were based on the BSSVD guidance. All BSSVD and British Society for Colposcopy and Cervical Pathology or BSCCP members were surveyed via two electronic questionnaires. Results demonstrate that the majority of specialist vulval clinics in the UK are non-compliant with the standards set out for specialist vulval services. The majority of clinicians would support the introduction of clinical nurse specialists to vulval services, but there is need for development of a national training programme. In conclusion, significant improvements are required in provision of patient information, guidelines, access to multidisciplinary services, multidisciplinary team or MDT processes and data recording in UK specialist vulval services.
    MeSH term(s) Attitude of Health Personnel ; Female ; Humans ; Medical Audit/statistics & numerical data ; Nurse Practitioners ; Standard of Care ; United Kingdom ; Vulvar Diseases/therapy
    Language English
    Publishing date 2016
    Publishing country England
    Document type Journal Article
    ZDB-ID 604639-3
    ISSN 1364-6893 ; 0144-3615
    ISSN (online) 1364-6893
    ISSN 0144-3615
    DOI 10.3109/01443615.2015.1072810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Local analgesia in early and late stages of labour.

    Nunns, D

    British journal of anaesthesia

    1998  Volume 81, Issue 1, Page(s) 102–103

    MeSH term(s) Analgesia, Epidural/methods ; Analgesia, Obstetrical/methods ; Anesthetics, Local/administration & dosage ; Bupivacaine/administration & dosage ; Female ; Humans ; Pregnancy
    Chemical Substances Anesthetics, Local ; Bupivacaine (Y8335394RO)
    Language English
    Publishing date 1998-07
    Publishing country England
    Document type Letter
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1093/bja/81.1.102-a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Vulvodynia and the primary health care physician.

    Nunns, D

    AIDS patient care and STDs

    1997  Volume 11, Issue 5, Page(s) 345–351

    MeSH term(s) Female ; Humans ; Hygiene ; Pain/etiology ; Patient Education as Topic ; Primary Health Care ; Vulvar Diseases/complications ; Vulvar Diseases/diagnosis ; Vulvar Diseases/drug therapy ; Vulvar Diseases/epidemiology ; Vulvar Diseases/etiology
    Language English
    Publishing date 1997-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1326868-5
    ISSN 1557-7449 ; 1087-2914 ; 0893-5068
    ISSN (online) 1557-7449
    ISSN 1087-2914 ; 0893-5068
    DOI 10.1089/apc.1997.11.345
    Database MEDical Literature Analysis and Retrieval System OnLINE

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