LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article: A case report of multi-step management of extracranial carotid artery aneurysm and carotid-cavernous fistula combination in patients.

    Nurimanov, Chingiz / Makhambetov, Yerbol / Kaliyev, Assylbek / Akshulakov, Serik

    Frontiers in neurology

    2023  Volume 14, Page(s) 1120786

    Abstract: Extracranial carotid artery aneurysms (ECAA) and carotid-cavernous fistulas (CCF) are rare arterial pathologies with severe complications and increased risk of mortality. The optimal treatment approach for this combined condition is a topic of debate ... ...

    Abstract Extracranial carotid artery aneurysms (ECAA) and carotid-cavernous fistulas (CCF) are rare arterial pathologies with severe complications and increased risk of mortality. The optimal treatment approach for this combined condition is a topic of debate among neurosurgeons and neuroradiologists, and a standardized treatment protocol has yet to be established. The aim of this case report was to demonstrate the management of a rare combination of ECAA and CCF in patients. The treatment strategy included a two-step procedure of endovascular embolization of CCF followed by dual antiplatelet therapy and endovascular stenting of an aneurysm. Control angiograms showed the exclusion of an aneurysm from the blood circulation and CCF symptoms were resolved.
    Language English
    Publishing date 2023-04-06
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2023.1120786
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: An Uncommon Case of Moyamoya Syndrome Is Accompanied by an Arteriovenous Malformation with the Involvement of Dural Arteries.

    Nurimanov, Chingiz / Mammadinova, Iroda / Makhambetov, Yerbol / Akshulakov, Serik

    International journal of molecular sciences

    2023  Volume 24, Issue 6

    Abstract: 1) Background: This report describes the surgical management of a case of concurrent AVM with the involvement of dural arteries and moyamoya syndrome. Given the infrequency of this combination, there is currently no established management strategy ... ...

    Abstract (1) Background: This report describes the surgical management of a case of concurrent AVM with the involvement of dural arteries and moyamoya syndrome. Given the infrequency of this combination, there is currently no established management strategy available. (2) Case Description: A 49-year-old male patient with multiple symptoms including headaches, tinnitus, and visual impairment diagnosed with the coexistence of an arteriovenous malformation with the involvement of dural arteries and moyamoya syndrome was admitted to the national tertiary hospital. The patient underwent surgical management through embolization of the AVM from the afferents of the dural arteries, which has resulted in positive clinical outcomes. However, this approach may not be suitable for all cases, and a multidisciplinary team approach may be required to develop an individualized treatment strategy. (3) Conclusion: The contradictory nature of the treatment approaches in cases of combined AVM with the involvement of dural arteries and MMD highlights the complex nature of this condition and the need for further research to identify the most effective treatment strategies.
    MeSH term(s) Male ; Humans ; Middle Aged ; Moyamoya Disease/complications ; Moyamoya Disease/diagnosis ; Intracranial Arteriovenous Malformations/complications ; Intracranial Arteriovenous Malformations/diagnostic imaging ; Arteries ; Treatment Outcome
    Language English
    Publishing date 2023-03-21
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24065911
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Conference proceedings: Effect of Endovascular Embolization on Seizure Presentation in Patients with Medium and High-Grade B

    Makhambetov, Yerbol / Nurimanov, Chingiz / Kaliyev, Assylbek

    The Arab Journal of Interventional Radiology

    2023  Volume 07, Issue S 01

    Event/congress PAIRS 2023 Annual Congress, Grand Hyatt Hotel, Dubai, UAE, 2023-02-11
    Language English
    Publishing date 2023-02-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2542-7083 ; 2542-7075
    ISSN (online) 2542-7083
    ISSN 2542-7075
    DOI 10.1055/s-0043-1763325
    Database Thieme publisher's database

    More links

    Kategorien

  4. Article: Long-Term Outcomes of Endovascular Embolization in a Vein of Galen Aneurysmal Malformation: A Single-Center Experience.

    Nurimanov, Chingiz / Makhambetov, Yerbol / Menlibayeva, Karashash / Nurakay, Nurtay / Makhambetov, Nursultan / Zholdybayeva, Elena / Akshulakov, Serik

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 16

    Abstract: Background: A vein of Galen aneurysmal malformation (VGAM) is a rare congenital cerebral vascular condition with a high mortality rate if left untreated. This study describes the long-term outcomes of patients with VGAM, who were treated with ... ...

    Abstract Background: A vein of Galen aneurysmal malformation (VGAM) is a rare congenital cerebral vascular condition with a high mortality rate if left untreated. This study describes the long-term outcomes of patients with VGAM, who were treated with endovascular embolization.
    Methods: This retrospective analysis focused on VGAM patients who underwent one or more endovascular embolization sessions between January 2008 and December 2022. The study included newborns and children under 18 years. Data encompassed clinical and demographic characteristics, types of endovascular embolization, treatment complications, mortality rates, and long-term outcomes.
    Results: Out of 22 VGAM cases, the majority were boys (86.36%), and the average age of the participants was 38 months, ranging from 25 days to 17 years. Endovascular embolization using liquid embolizing agents was the most common intervention (50%), and around 73% of patients underwent multiple sessions. Some patients underwent ventriculoperitoneal shunting (VPS) due to persistent hydrocephalus. In long-term outcomes, four patients (18.2%) showed developmental delays, and 16 patients (72.7%) had a positive outcome.
    Conclusions: Combining endovascular therapy with a comprehensive management strategy significantly reduces mortality rates and improves the possibility of normal neurological development in patients.
    Language English
    Publishing date 2023-08-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13162704
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Whole-Exome Sequencing Reveals Pathogenic SIRT1 Variant in Brain Arteriovenous Malformation: A Case Report.

    Mukhtarova, Kymbat / Zholdybayeva, Elena / Kairov, Ulykbek / Akhmetollayev, Ilyas / Nurimanov, Chingiz / Kulmirzayev, Marat / Makhambetov, Yerbol / Ramankulov, Yerlan

    Genes

    2022  Volume 13, Issue 10

    Abstract: Arteriovenous malformations of the brain (bAVMs) are plexuses of pathological arteries and veins that lack a normal capillary system between them. Intracranial hemorrhage (hemorrhagic stroke) is the most frequent clinical manifestation of AVM, leading to ...

    Abstract Arteriovenous malformations of the brain (bAVMs) are plexuses of pathological arteries and veins that lack a normal capillary system between them. Intracranial hemorrhage (hemorrhagic stroke) is the most frequent clinical manifestation of AVM, leading to lethal outcomes that are especially high among children and young people. Recently, high-throughput genome sequencing methods have made a notable contribution to the research progress in this subject. In particular, whole-exome sequencing (WES) methods allow the identification of novel mutations. However, the genetic mechanism causing AVM is still unclear. Therefore, the aim of this study was to investigate the potential genetic mechanism underlying AVM. We analyzed the WES data of blood and tissue samples of a 30-year-old Central Asian male diagnosed with AVM. We identified 54 polymorphisms in 43 genes. After in-silica overrepresentation enrichment analysis of the polymorphisms, the SIRT1 gene variant (g.67884831C>T) indicated a possible molecular mechanism of bAVM. Further studies are required to evaluate the functional impact of SIRT1 g.67884831C>T, which may warrant further replication and biological investigations related to sporadic bAVM.
    MeSH term(s) Child ; Humans ; Male ; Adolescent ; Adult ; Exome Sequencing ; Sirtuin 1/genetics ; Intracranial Arteriovenous Malformations/genetics ; Intracranial Arteriovenous Malformations/pathology ; Brain/pathology ; Silicon Dioxide
    Chemical Substances Sirtuin 1 (EC 3.5.1.-) ; Silicon Dioxide (7631-86-9) ; SIRT1 protein, human (EC 3.5.1.-)
    Language English
    Publishing date 2022-09-21
    Publishing country Switzerland
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes13101689
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Management of giant internal carotid aneurysm by extracranial-intracranial bypass and flow diverter stent.

    Kaliyev, Assylbek / Makhambetov, Yerbol / Medetov, Yerkin / Kulmirzayev, Marat / Dusembayev, Serik / Nurimanov, Chingiz / Kunakbayev, Baurzhan / Akshulakov, Serik

    British journal of neurosurgery

    2021  Volume 37, Issue 6, Page(s) 1893–1897

    Abstract: Flow diverter stents have become the standard approach to managing intracranial aneurysms; however, in some cases of complex, wide-necked aneurysms, poor outcomes due to stent occlusion have been reported. We report the case of a giant internal carotid ... ...

    Abstract Flow diverter stents have become the standard approach to managing intracranial aneurysms; however, in some cases of complex, wide-necked aneurysms, poor outcomes due to stent occlusion have been reported. We report the case of a giant internal carotid artery aneurysm treated by high-flow extracranial-intracranial (EC-IC) bypass with flow diverter deployment. Seven months post-operatively, radiographic imaging demonstrated occlusion of the stent and parent artery, with further ischemic events prevented by collateral flow from the high flow bypass. This case demonstrates the continued utility of EC-IC bypass in the endovascular era, especially as a rescue tool in cases of delayed stent occlusion.
    MeSH term(s) Humans ; Carotid Artery, Internal/diagnostic imaging ; Carotid Artery, Internal/surgery ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/surgery ; Carotid Artery Diseases/diagnostic imaging ; Carotid Artery Diseases/surgery ; Neurosurgical Procedures/methods ; Stents ; Treatment Outcome
    Language English
    Publishing date 2021-07-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 639029-8
    ISSN 1360-046X ; 0268-8697
    ISSN (online) 1360-046X
    ISSN 0268-8697
    DOI 10.1080/02688697.2021.1947974
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top