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  1. Article ; Online: Which Pathology Education Method Is More Useful in Active Professional Life? A Survey of Clinicians

    Sibel Sensu / Hikmet Koçak / Yeşim Saliha Gürbüz / Nuriye Fışgın / Nusret Erdoğan

    Tıp Eğitimi Dünyası, Vol 21, Iss 63, Pp 69-

    2022  Volume 83

    Abstract: Aim: In this study on physicians who graduated at 2000 and after, contribution of the pathology education they received in medical faculties to their active professional lives, its adequacy and necessity, and their opinions and suggestions were examined ... ...

    Abstract Aim: In this study on physicians who graduated at 2000 and after, contribution of the pathology education they received in medical faculties to their active professional lives, its adequacy and necessity, and their opinions and suggestions were examined.Methods: An open-ended, multiple choice and Likert scale format digital questionnaire consisting of 12 questions was filled by the consenting physicians who graduated in 2000 and later.Results: Total 107 physicians (39 (36.4%) clinical, 38 (35.5%) surgical sciences and 30 (28%) general practitioners) participated in the study. Forty-one physicians (38%) took the pathology course only in the third year. Didactic training was most frequently accompanied by microscopy (n = 94, 87.9%) training. Sixty-six (61.68%) physicians additionally received macroscopy training. Pathology education was very useful and beneficial for their current professional life for 75% physicians and was very sufficient and quite sufficient in 45% physicians. There was a statistically significant relationship between the benefit of pathology in professional life and the adequacy of the education received (p = 0.01). The usability of the knowledge (n = 89, 83.2%), the educational methods (n = 78, 72.9%), and the characteristics of the educator (n = 75, 70.1%) were rated as the most important factors for its benefit in active professional life. Case discussions (n= 79, 72.9%), macroscopy (n = 65, 60.7%), and microscopy laboratory study (n= 62, 57.9%), problem-based learning (PBL) (n = 61, 57.0%), and observation in hospital laboratory ( n= 51, 47.6%) are recommended besides objective structured practical exam (OSPE) (n = 85, 79.4%) andobjective structured clinical exam (OSCE) (n = 76, 71.0%). Conclusions: Pathology education will be helpful in active professional life if the curriculum is usable, integrated with the clinic and delivered with diversified up-to-date learning methods. The benefit of pathology education increases in parallel to its adequacy. Also, surgical and internal sciences ...
    Keywords medical education ; pathology ; postgraduate ; curriculum ; tıp eğitimi ; patoloji ; mezuniyet sonrası ; müfredat ; Education (General) ; L7-991 ; Medicine (General) ; R5-920
    Subject code 370
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Association for Development of Medical Education
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Does the Pathology Education Received in the Undergraduate Preclinical Years Provide Benefits in the Clinical Education Period? A Survey on 5th Grade Medical Students

    Sibel ŞENSU / Sevcan KUTLU / Yeşim Saliha GÜRBÜZ / Hikmet KOÇAK / Nuriye TAŞDELEN FIŞGIN / Nusret ERDOĞAN

    Namık Kemal Tıp Dergisi, Vol 10, Iss 1, Pp 101-

    2022  Volume 107

    Abstract: Aim:We aimed to evaluate the perceptions of 5th grade medical faculty students regarding the adequacy of the pathology education they received in the preclinical period and the benefit of it in clinical clerkship training,Materials and Methods:A 14- ... ...

    Abstract Aim:We aimed to evaluate the perceptions of 5th grade medical faculty students regarding the adequacy of the pathology education they received in the preclinical period and the benefit of it in clinical clerkship training,Materials and Methods:A 14-question digital questionnaire consisting of open-ended and multiple choice questions was created and sent via e-mail and whatsapp to the students who were in the 3rd grade at our faculty of medicine in the 2018-2019 academic year and were in the 5th grade in the 2020-2021 academic year. The results were analyzed and statistically evaluated.Results:56% of the students found the pathology education they received sufficient. Microscopy and macroscopy training, visiting the pathology laboratory, case-based discussion and self-study of the resources suggested by the instructors had a significant contribution to students’ learning (p<0.05). The medical education received in the 3rd grade offered a significant benefit during the clinical clerkship period (p=0.02). The greatest benefit was obtained from macroscopy education and the students strongly recommended macroscopy and case based learning. According to 75% of the students, the education they received helped to understand the disease mechanism.Conclusion:The medical pathology education formed the basis of the clinical clerkship period and case-based learning and macroscopy training were the most effective methods. To be more useful, didactic lessons should be combined with different and up-to-date learning methods and the curriculum should be updated. Standardization of pathology education in medical faculties is also an issue that needs to be addressed.
    Keywords undergraduate medical education ; pathology ; macroscopy training ; case based learning ; curriculum ; Medicine ; R
    Subject code 370
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Galenos Yayincilik
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Angiogenesis in Breast Cancers without Lymph Node Metastasis

    Nusret ERDOĞAN / Aylin DENGİZMEN / Ayşenur AKYILDIZ İĞDEM / Elife ŞAHAN / Ümit SEZA TETİKKURT

    Türk Patoloji Dergisi , Vol 26, Iss 2, Pp 136-

    2010  Volume 139

    Abstract: Objective: Many studies have been focused on angiogenesis as a possible prognostic factor, recently. In this study, we evaluated microvessel density by CD34 in primary tumors of the patients with lymph node negative breast carcinomas and compared the ... ...

    Abstract Objective: Many studies have been focused on angiogenesis as a possible prognostic factor, recently. In this study, we evaluated microvessel density by CD34 in primary tumors of the patients with lymph node negative breast carcinomas and compared the results with prognostic parameters.Material and Method: 31 patients with invasive breast carcinomas without axillary lymph node metastasis were included in this study. Microvessel density was assessed by CD34 staining in the primary tumor and compared with the tumor type and prognostic parameters such as age, tumor size, nuclear grade, lymphatic vessel invasion, and estrogen and progesteron reseptor status. CD34 staining was evaluated in three areas by x200 magnification.Results: The mean value microvessel density of CD34 staining in the primary tumor was 43 (minimum 19 and maximum 100). There was a significant relationship between microvessel density and progesterone receptor expression. microvessel density was higher in lobular type breast carcinoma.Conclusion: The correlation between progesterone receptor status and microvessel density should be further confirmed by prospective studies. The high microvessel density rate in lobular carcinoma may be attributed to abundance of stromal cells or to the low number of patients.
    Keywords Breast cancer ; Metastasis ; Angiogenesis ; Progesterone receptor ; Pathology ; RB1-214 ; Medicine ; R ; DOAJ:Pathology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 610 ; 616
    Language Turkish
    Publishing date 2010-05-01T00:00:00Z
    Publisher Federation of Turkish Society of Pathology
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Cox-2 Expression and Microvessel Density in Clear Cell Type Renal Cell Carcinoma

    Hasan GÜÇER / Elife ŞAHAN / Ayşenur AKYILDIZ İĞDEM / Ü. Seza TETİKKURT / Nusret ERDOĞAN

    Türk Patoloji Dergisi , Vol 25, Iss 2, Pp 13-

    2009  Volume 19

    Abstract: Objective: Overexpression of cyclooxygenase-2 (COX-2) and its association with angiogenesis have been shown in various carcinomas. In this study, we investigated COX-2 expression in clear cell type renal cell carcinoma and its association with ... ...

    Abstract Objective: Overexpression of cyclooxygenase-2 (COX-2) and its association with angiogenesis have been shown in various carcinomas. In this study, we investigated COX-2 expression in clear cell type renal cell carcinoma and its association with microvessel density and various clinicopathologic parameters.Material and Method: Fifty cases of clear cell type renal cell carcinoma that underwent radical nephrectomy were included in this study. Th e status of COX-2 expression was examined immunohistochemically. Microvessel density in the neoplasm was estimated using the computerized image-analizer system. We evaluated the correlation between COX-2 expression, microvessel density and clinicopathologic findings.Results: COX-2 expression was observed in 76% of the cases. Th ere was no association between COX-2 expression and microvessel density, age, sex, tumor size, nuclear grade and stage (p>0.05).Conclusion: Most clear cell type renal cell carcinomas expressed COX-2, but there was no relationship between COX-2 and various clinicopathologic parameters. Similar studies to explore therapeutic agents that target these specialities can be useful in the treatment of renal cell carcinomas which show COX-2 expression and high vascularity.
    Keywords Renal cell carcinoma ; COX-2 ; Immunohistochemistry ; Microvessel density ; Pathology ; RB1-214 ; Medicine ; R ; DOAJ:Pathology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 616
    Language Turkish
    Publishing date 2009-06-01T00:00:00Z
    Publisher Federation of Turkish Society of Pathology
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Eradication of Helicobacter pylori in follicular and nonfollicular gastritis.

    Mehmet, Sokmen / Ozdal, Ersoy / Kamil, Ozdil / Beşir, Kesici / Huseyin, Demirsoy / Nihat, Akbayir / Cigdem, Ersoy Yazici / Nusret, Erdogan

    Hepato-gastroenterology

    2009  Volume 56, Issue 91-92, Page(s) 930–934

    Abstract: Background/aims: Effective eradication therapy of Helicobacter pylori (Hp) in non-follicular type gastritis is commonly demonstrated by many studies. In contrast, some other studies show that the eradication of Hp is low in follicular type gastritis. ... ...

    Abstract Background/aims: Effective eradication therapy of Helicobacter pylori (Hp) in non-follicular type gastritis is commonly demonstrated by many studies. In contrast, some other studies show that the eradication of Hp is low in follicular type gastritis. However, the subject concerning the comparison of the results of triple-drug Hp eradication treatment between follicular and nonfollicular type gastritis is still unclear because of the paucity of studies. The aim of this study was to compare the results of Hp eradication therapy between follicular and non-follicular type gastritis.
    Methodology: Two age- and sex-matched groups, consisting of 21 patients with follicular type and 23 patients with nonfollicular type gastritis associated with Hp (histopathologically diagnosed after endoscopic procedure), were enrolled into our study. Triple-drug Hp eradication therapy [lansoprazole (L) 30 mg bid, amoxicillin (A) 1000 g bid and clarithromycin (C) 500 mg bid] was given to all patients in both groups for two weeks. Control for the eradication of Hp was performed by endoscopic biopsy (3 months after treatment) in the follicular group and by urea-breath test (1 month after treatment) in the nonfollicular group. Eradication of the follicles in follicular type gastritis was also observed in the control endoscopic biopsies. For the statistical analysis, SPSS 11 for Windows was used and paired-samples t-test was performed. p<0.05 was considered as significant.
    Results: In total, 66 patients were enrolled into the study. All were histopathologically diagnosed as having Hp-associated gastritis (31 follicular and 35 nonfollicular) and started on triple-drug Hp eradication therapy. Only 44 of these patients (21 follicular gastritis and 23 nonfollicular gastritis) completed 2 weeks of treatment. The other 22 patients were not able to complete the treatment because of not taking the drugs properly or of the side-effects of the drugs. Patient compliance ratio to the treatment was 67.7%. The ratios for Hp eradication in follicular and nonfollicular type gastritis were found to be 43% and 74% respectively. Lymphoid follicles in 43% of patients with follicular gastritis disappeared after the eradication therapy.
    Conclusions: Lymphoid follicles, which are thought to be the primary lesions of low-grade Mucosa associated lymphoid tissue (MALT) tumors, come out frequently in Hp-associated gastritis. Although the eradication of Hp is said to be difficult in the presence of lymphoid follicles, there is still limited knowledge about this situation. The ratio of effective eradication of Hp with LAC combination therapy in nonfollicular gastritis is nearly over 80%. However, in our study we observed an obvious lower Hp eradication ratio in follicular type gastritis than in nonfollicular gastritis. Thus, in order to achieve higher Hp eradication ratios in follicular gastritis, duration of the triple-drug treatment might be lengthened or bismuth salt preparations need to be added to triple combination therapies.
    MeSH term(s) 2-Pyridinylmethylsulfinylbenzimidazoles/administration & dosage ; Adult ; Amoxicillin/administration & dosage ; Anti-Bacterial Agents/administration & dosage ; Anti-Ulcer Agents/administration & dosage ; Clarithromycin/administration & dosage ; Drug Therapy, Combination ; Female ; Gastritis/drug therapy ; Gastritis/microbiology ; Gastritis/pathology ; Helicobacter Infections/drug therapy ; Helicobacter Infections/pathology ; Helicobacter pylori ; Humans ; Lansoprazole ; Male ; Middle Aged ; Prospective Studies ; Treatment Outcome ; Young Adult
    Chemical Substances 2-Pyridinylmethylsulfinylbenzimidazoles ; Anti-Bacterial Agents ; Anti-Ulcer Agents ; Lansoprazole (0K5C5T2QPG) ; Amoxicillin (804826J2HU) ; Clarithromycin (H1250JIK0A)
    Language English
    Publishing date 2009-05
    Publishing country Greece
    Document type Controlled Clinical Trial ; Journal Article
    ZDB-ID 801013-4
    ISSN 0172-6390
    ISSN 0172-6390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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