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  1. Book ; Online ; E-Book: Climate, ticks and disease

    Alasmari, Saeed / Alexander, Neil / Alkishe, Abdelghafar / Arai, Reiko / Bastos, Armanda / Bechara, Gervasio Henrique / Beier, John / Benelli, Giovanni / Benoit, Joshua / Nuttall, Patricia A.

    (CABI climate change ; 12)

    2022  

    Abstract: This book brings together expert opinions from scientists to consider the evidence for climate change and its impacts on ticks and tick-borne infections, and provide predictions for the future. ...

    Author's details edited by Pat Nuttall
    Series title CABI climate change ; 12
    CABI climate change series
    Collection CABI climate change series
    Abstract This book brings together expert opinions from scientists to consider the evidence for climate change and its impacts on ticks and tick-borne infections, and provide predictions for the future.
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (707 Seiten)
    Publisher CABI
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021173765
    ISBN 978-1-78924-965-1 ; 9781789249637 ; 1-78924-965-1 ; 1789249635
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Tick saliva and its role in pathogen transmission.

    Nuttall, Patricia A

    Wiener klinische Wochenschrift

    2019  Volume 135, Issue 7-8, Page(s) 165–176

    Abstract: Tick saliva is a complex mixture of peptidic and non-peptidic molecules that aid engorgement. The composition of tick saliva changes as feeding progresses and the tick counters the dynamic host response. Ixodid ticks such as Ixodes ricinus, the most ... ...

    Abstract Tick saliva is a complex mixture of peptidic and non-peptidic molecules that aid engorgement. The composition of tick saliva changes as feeding progresses and the tick counters the dynamic host response. Ixodid ticks such as Ixodes ricinus, the most important tick species in Europe, transmit numerous pathogens that cause debilitating diseases, e.g. Lyme borreliosis and tick-borne encephalitis. Tick-borne pathogens are transmitted in tick saliva during blood feeding; however, saliva is not simply a medium enabling pathogen transfer. Instead, tick-borne pathogens exploit saliva-induced modulation of host responses to promote their transmission and infection, so-called saliva-assisted transmission (SAT). Characterization of the saliva factors that facilitate SAT is an active area of current research. Besides providing new insights into how tick-borne pathogens survive in nature, the research is opening new avenues for vaccine development.
    MeSH term(s) Humans ; Animals ; Saliva ; Lyme Disease ; Ixodes/physiology ; Europe
    Language English
    Publishing date 2019-05-06
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 200462-8
    ISSN 1613-7671 ; 0043-5325 ; 0300-5178
    ISSN (online) 1613-7671
    ISSN 0043-5325 ; 0300-5178
    DOI 10.1007/s00508-019-1500-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 902: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Wonders of tick saliva.

    Nuttall, Patricia A

    Ticks and tick-borne diseases

    2018  Volume 10, Issue 2, Page(s) 470–481

    Abstract: Saliva of ticks is arguably the most complex saliva of any animal. This is particularly the case for ixodid species that feed for many days firmly attached to the same skin site of their obliging host. Sequencing and spectrometry technologies combined ... ...

    Abstract Saliva of ticks is arguably the most complex saliva of any animal. This is particularly the case for ixodid species that feed for many days firmly attached to the same skin site of their obliging host. Sequencing and spectrometry technologies combined with bioinformatics are enumerating ingredients in the saliva cocktail. The dynamic and expanding saliva recipe is helping decipher the wonderous activities of tick saliva, revealing how ticks stealthily hide from their hosts while satisfying their gluttony and sharing their individual resources. This review takes a tick perspective on the composition and functions of tick saliva, covering water balance, gasket and holdfast, control of host responses, dynamics, individuality, mate guarding, saliva-assisted transmission, and redundancy. It highlights areas sometimes overlooked - feeding aggregation and sharing of sialomes, and the contribution of salivary gland storage granules - and questions whether the huge diversity of tick saliva molecules is 'redundant' or more a reflection on the enormous adaptability wonderous saliva confers on ticks.
    MeSH term(s) Animals ; Arthropod Proteins/analysis ; Arthropod Proteins/chemistry ; Computational Biology ; Female ; Guinea Pigs ; Humans ; Male ; Mice ; Saliva/chemistry ; Salivary Glands/chemistry ; Salivary Proteins and Peptides/analysis ; Salivary Proteins and Peptides/chemistry ; Ticks/chemistry
    Chemical Substances Arthropod Proteins ; Salivary Proteins and Peptides
    Language English
    Publishing date 2018-11-12
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2541872-5
    ISSN 1877-9603 ; 1877-959X
    ISSN (online) 1877-9603
    ISSN 1877-959X
    DOI 10.1016/j.ttbdis.2018.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Wonders of tick saliva

    Nuttall, Patricia A

    Ticks and tick-borne diseases. 2019 Feb., v. 10, no. 2

    2019  

    Abstract: Saliva of ticks is arguably the most complex saliva of any animal. This is particularly the case for ixodid species that feed for many days firmly attached to the same skin site of their obliging host. Sequencing and spectrometry technologies combined ... ...

    Abstract Saliva of ticks is arguably the most complex saliva of any animal. This is particularly the case for ixodid species that feed for many days firmly attached to the same skin site of their obliging host. Sequencing and spectrometry technologies combined with bioinformatics are enumerating ingredients in the saliva cocktail. The dynamic and expanding saliva recipe is helping decipher the wonderous activities of tick saliva, revealing how ticks stealthily hide from their hosts while satisfying their gluttony and sharing their individual resources. This review takes a tick perspective on the composition and functions of tick saliva, covering water balance, gasket and holdfast, control of host responses, dynamics, individuality, mate guarding, saliva-assisted transmission, and redundancy. It highlights areas sometimes overlooked – feeding aggregation and sharing of sialomes, and the contribution of salivary gland storage granules – and questions whether the huge diversity of tick saliva molecules is ‘redundant’ or more a reflection on the enormous adaptability wonderous saliva confers on ticks.
    Keywords bioinformatics ; granules ; hosts ; ingredients ; mate guarding ; saliva ; salivary glands ; spectroscopy ; tick-borne diseases ; ticks
    Language English
    Dates of publication 2019-02
    Size p. 470-481.
    Publishing place Elsevier GmbH
    Document type Article
    ZDB-ID 2541872-5
    ISSN 1877-9603 ; 1877-959X
    ISSN (online) 1877-9603
    ISSN 1877-959X
    DOI 10.1016/j.ttbdis.2018.11.005
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Editorial: Tick Saliva: Secret to Blood Feeding Success.

    Sonenshine, Daniel E / Nuttall, Patricia A / Narasimhan, Sukanya

    Frontiers in cellular and infection microbiology

    2022  Volume 12, Page(s) 885240

    Language English
    Publishing date 2022-03-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2022.885240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Molecular characterization of tick-virus interactions.

    Nuttall, Patricia A

    Frontiers in bioscience (Landmark edition)

    2009  Volume 14, Issue 7, Page(s) 2466–2483

    Abstract: All viruses infecting ticks (with one possible exception) are arboviruses; their life cycle depends on infection and replication in both tick and vertebrate host cells. Little is known of arbovirus-tick cell interactions even though tick-borne viruses ... ...

    Abstract All viruses infecting ticks (with one possible exception) are arboviruses; their life cycle depends on infection and replication in both tick and vertebrate host cells. Little is known of arbovirus-tick cell interactions even though tick-borne viruses spend most of their existence in ticks. A distinct selection pressure on tick-borne viruses is the intracellular process of bloodmeal digestion in ticks (contrasting with insects) This may explain the pronounced differences in surface structure of tick-borne and insect-borne orbiviruses. Some indications of molecular interactions can be extrapolated from vertebrate cells, such as utilisation of aggresome pathways. Although many (if not all) tick-borne viruses exploit the immunomodulatory effects of tick saliva on the vertebrate host, there is no evidence they interact directly with saliva molecules. However, the most fundamental question to address is the benign infection of arboviruses in tick cells compared with their cytopathic effect in vertebrate cells. As the tick proteome is unravelled, its interaction with the viral proteome should help explain the interactions between ticks and the many important viruses they transmit.
    MeSH term(s) Animals ; Arachnid Vectors ; Host-Parasite Interactions ; Tick-Borne Diseases/transmission ; Tick-Borne Diseases/virology ; Ticks/virology ; Virus Physiological Phenomena ; Viruses/genetics ; Viruses/isolation & purification
    Language English
    Publishing date 2009-01-01
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2704569-9
    ISSN 2768-6698 ; 1093-9946
    ISSN (online) 2768-6698
    ISSN 1093-9946
    DOI 10.2741/3390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Prevalence of Borrelia burgdorferi and Borrelia miyamotoi in questing Ixodes ricinus ticks from four sites in the UK.

    Layzell, Scott J / Bailey, Daniel / Peacey, Mick / Nuttall, Patricia A

    Ticks and tick-borne diseases

    2017  Volume 9, Issue 2, Page(s) 217–224

    Abstract: Borrelia miyamotoi is a spirochete bacterium related to Borrelia burgdorferi sensu lato, the cause of Lyme borreliosis, and vectored by ticks. In 2014, B. miyamotoi was identified in three questing Ixodes ricinus collected in the UK. We sought to confirm ...

    Abstract Borrelia miyamotoi is a spirochete bacterium related to Borrelia burgdorferi sensu lato, the cause of Lyme borreliosis, and vectored by ticks. In 2014, B. miyamotoi was identified in three questing Ixodes ricinus collected in the UK. We sought to confirm the presence of B. miyamotoi in the UK. Ticks were collected from four locations not previously investigated for B. miyamotoi or B. burgdorferi s.l. and of which two are considered as Lyme borreliosis "hotspots" based on hospital records of the disease. We independently confirm that B. miyamotoi is present in the UK and support the view that B. miyamotoi is likely to have a broad geographic distribution, at low levels. Our study also adds to the existing data on the distribution of B. burgdorferi s.l. in the UK and demonstrates that although the two "hotspots" had relatively high tick densities, they did not have the highest proportion of infected ticks.
    MeSH term(s) Animals ; Borrelia/isolation & purification ; Borrelia burgdorferi/isolation & purification ; England ; Ixodes/microbiology ; Ixodes/physiology ; Multiplex Polymerase Chain Reaction ; Population Density ; Prevalence
    Language English
    Publishing date 2017-09-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2541872-5
    ISSN 1877-9603 ; 1877-959X
    ISSN (online) 1877-9603
    ISSN 1877-959X
    DOI 10.1016/j.ttbdis.2017.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Increased Relative Risk of Tick-Borne Encephalitis in Warmer Weather.

    Daniel, Milan / Danielová, Vlasta / Fialová, Alena / Malý, Marek / Kříž, Bohumír / Nuttall, Patricia A

    Frontiers in cellular and infection microbiology

    2018  Volume 8, Page(s) 90

    Abstract: Tick-borne encephalitis (TBE) is a serious acute neuroinfection of humans caused by a tick-borne flavivirus. The disease is typically seasonal, linked to the host-seeking activity ... ...

    Abstract Tick-borne encephalitis (TBE) is a serious acute neuroinfection of humans caused by a tick-borne flavivirus. The disease is typically seasonal, linked to the host-seeking activity of
    MeSH term(s) Animals ; Arachnid Vectors/physiology ; Arachnid Vectors/virology ; Czech Republic/epidemiology ; Encephalitis Viruses, Tick-Borne/genetics ; Encephalitis Viruses, Tick-Borne/isolation & purification ; Encephalitis Viruses, Tick-Borne/physiology ; Encephalitis, Tick-Borne/epidemiology ; Encephalitis, Tick-Borne/transmission ; Encephalitis, Tick-Borne/virology ; Humans ; Incidence ; Ixodes/physiology ; Ixodes/virology ; Seasons ; Temperature ; Weather
    Language English
    Publishing date 2018-03-22
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2018.00090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Ticks

    Bowman, Alan. S / Nuttall, Patricia A

    biology, disease and control

    2008  

    Author's details edited by Alan S. Bowman, Patricia. A. Nuttall
    Keywords Ticks as carriers of disease. ; Ticks.
    Language English
    Size xii, 506 p. :, ill., maps ;, 26 cm.
    Publisher Cambridge University Press
    Publishing place Cambridge, UK ; New York
    Document type Book
    ISBN 9780521867610 ; 0521867614
    Database NAL-Catalogue (AGRICOLA)

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  10. Book: Ticks

    Bowman, Alan. S / Nuttall, Patricia A

    biology, disease, and control

    2008  

    Author's details edited by Alan S. Bowman, Patricia. A. Nuttall
    MeSH term(s) Tick-Borne Diseases ; Ticks/physiology ; Tick Control/methods
    Language English
    Size xii, 506 p. :, ill.
    Publisher Cambridge University Press
    Publishing place Cambridge ; New York
    Document type Book
    ISBN 9780521867610 ; 0521867614
    Database Catalogue of the US National Library of Medicine (NLM)

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