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  1. Article ; Online: Cardiorespiratory and autonomic adjustments to exercise with healthy ageing: considerations with extreme heat exposure and hydration.

    O'Connell, Cameron T / Reed, Emma L / Chapman, Christopher L

    The Journal of physiology

    2023  Volume 601, Issue 14, Page(s) 2759–2760

    MeSH term(s) Extreme Heat ; Healthy Aging ; Autonomic Nervous System ; Reflex ; Exercise ; Muscle, Skeletal ; Blood Pressure ; Hand Strength
    Language English
    Publishing date 2023-05-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP284737
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Hypohydration attenuates increases in creatinine clearance to oral protein loading and the renal hemodynamic response to exercise pressor reflex.

    Chapman, Christopher L / Holt, Sadie M / O'Connell, Cameron T / Brazelton, Shaun C / Medved, Hannah N / Howells, William A B / Reed, Emma L / Needham, Karen Wiedenfeld / Halliwill, John R / Minson, Christopher T

    Journal of applied physiology (Bethesda, Md. : 1985)

    2024  Volume 136, Issue 3, Page(s) 492–508

    Abstract: Insufficient hydration is prevalent among free living adults. This study investigated whether hypohydration ... ...

    Abstract Insufficient hydration is prevalent among free living adults. This study investigated whether hypohydration alters
    MeSH term(s) Female ; Male ; Young Adult ; Humans ; Creatinine ; Hand Strength ; Reflex ; Hemodynamics ; Water
    Chemical Substances Creatinine (AYI8EX34EU) ; Water (059QF0KO0R)
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00728.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Acute kidney injury biomarkers and hydration assessments following prolonged mild hypohydration in healthy young adults.

    Chapman, Christopher L / Holt, Sadie M / O'Connell, Cameron T / Brazelton, Shaun C / Howells, William A B / Medved, Hannah N / Reed, Emma L / Needham, Karen Wiedenfeld / Halliwill, John R / Minson, Christopher T

    American journal of physiology. Renal physiology

    2023  Volume 325, Issue 2, Page(s) F199–F213

    Abstract: The high prevalence of inadequate hydration (e.g., hypohydration and underhydration) is concerning given that extreme heat increases excess hospitalizations for fluid/electrolyte disorders and acute kidney injury (AKI). Inadequate hydration may also be ... ...

    Abstract The high prevalence of inadequate hydration (e.g., hypohydration and underhydration) is concerning given that extreme heat increases excess hospitalizations for fluid/electrolyte disorders and acute kidney injury (AKI). Inadequate hydration may also be related to renal and cardiometabolic disease development. This study tested the hypothesis that prolonged mild hypohydration increases the urinary AKI biomarker product of insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase-2 ([IGFBP7·TIMP-2]) compared with euhydration. In addition, we determined the diagnostic accuracy and optimal cutoffs of hydration assessments for discriminating positive AKI risk ([IGFBP·TIMP-2] >0.3 (ng/mL)
    MeSH term(s) Male ; Female ; Humans ; Young Adult ; Tissue Inhibitor of Metalloproteinase-2 ; Biomarkers ; Acute Kidney Injury/diagnosis ; Kidney ; Insulin-Like Growth Factor Binding Proteins ; Somatomedins
    Chemical Substances Tissue Inhibitor of Metalloproteinase-2 (127497-59-0) ; Biomarkers ; Insulin-Like Growth Factor Binding Proteins ; Somatomedins
    Language English
    Publishing date 2023-06-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 603837-2
    ISSN 1522-1466 ; 0363-6127
    ISSN (online) 1522-1466
    ISSN 0363-6127
    DOI 10.1152/ajprenal.00086.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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