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  1. Book: The Mayo Clinic manual of nuclear medicine

    O'Connor, Michael K.

    1996  

    Title variant Nuclear medicine
    Author's details ed. by Michael K. O'Connor
    Keywords Radionuclide Imaging / methods ; Radionuclide Imaging / instrumentation ; Nuclear Medicine / standards ; Quality Control ; Nuklearmedizin
    Subject Nuklearmedizinische Diagnostik
    Language English
    Size XIV, 592 S. : Ill., graph. Darst.
    Publisher Churchill Livingstone
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT007435110
    ISBN 0-443-07765-7 ; 978-0-443-07765-4
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Comment on "Radiation Doses and Risks in Breast Screening".

    Conners, Amy Lynn / Ellis, Richard / Fazzio, Robert T / Hruska, Carrie B / Hunt, Katie N / O'Connor, Michael K / Rhodes, Deborah J / Shermis, Robin

    Journal of breast imaging

    2024  Volume 2, Issue 6, Page(s) 519–520

    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbaa074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Risk of low-dose radiation and the BEIR VII report: A critical review of what it does and doesn't say.

    O'Connor, Michael K

    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

    2017  Volume 43, Page(s) 153–158

    Abstract: This article briefly reviews the history behind the BEIR VII report and the use of the linear no-threshold hypothesis. The BEIR VII committee considered four primary sources of data on the stochastic effects of ionizing radiation. These were ... ...

    Abstract This article briefly reviews the history behind the BEIR VII report and the use of the linear no-threshold hypothesis. The BEIR VII committee considered four primary sources of data on the stochastic effects of ionizing radiation. These were environmental studies, occupational studies, medical studies and studies on the atomic bomb survivors. These sources are briefly reviewed along with key studies that run counter to the LNT hypothesis. We review many of the assumptions, hypotheses and subjective decisions used to generate risk estimates in the BEIR VII report. Position statement by the Health Physics Society, American Association of Physicists in Medicine, and UNSCEAR support the conclusion that the risk estimates in the BEIR VII report should not be used for estimating cancer risks from low doses of ionizing radiation.
    MeSH term(s) Animals ; Humans ; Radiation Dosage ; Radiobiology/methods ; Risk ; Stochastic Processes
    Language English
    Publishing date 2017-11
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 1122650-x
    ISSN 1724-191X ; 1120-1797
    ISSN (online) 1724-191X
    ISSN 1120-1797
    DOI 10.1016/j.ejmp.2017.07.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Molecular breast imaging: an emerging modality for breast cancer screening.

    O'Connor, Michael K

    Breast cancer management

    2015  Volume 4, Issue 1, Page(s) 33–40

    Abstract: Screening mammography is recognized as an imperfect imaging tool that performs poorly in women with dense breast tissue - a limitation which has driven demand for supplemental screening techniques. One potential supplemental technique is molecular breast ...

    Abstract Screening mammography is recognized as an imperfect imaging tool that performs poorly in women with dense breast tissue - a limitation which has driven demand for supplemental screening techniques. One potential supplemental technique is molecular breast imaging (MBI). Significant improvements in gamma camera technology allow MBI to be performed at low radiation doses, comparable with those of tomosynthesis and mammography. A recent screening trial in women with dense breast tissue yielded a cancer detection rate of 3.2 per 1000 for mammography alone and 12.0 per 1000 for the combination of mammography and MBI. MBI also demonstrated a lower recall rate than that of mammography. MBI is a promising supplemental screening technique in women with dense breast tissue.
    Language English
    Publishing date 2015-01-08
    Publishing country England
    Document type Journal Article
    ISSN 1758-1923
    ISSN 1758-1923
    DOI 10.2217/BMT.14.49
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Molecular Breast Imaging in Patients with Suspicious Calcifications.

    Hunt, Katie N / Hruska, Carrie B / Johnson, Matthew P / Conners, Amy Lynn / O'connor, Michael K / Rhodes, Deborah J / Basappa, Susanna / Wahner-Roedler, Dietlind

    Journal of breast imaging

    2024  Volume 1, Issue 4, Page(s) 303–309

    Abstract: Objective: We evaluated the accuracy of molecular breast imaging (MBI)-a nuclear medicine technique that employs dedicated dual-detector, cadmium zinc telluride gamma cameras to image the functional uptake of a radiopharmaceutical (typically Tc-99m ... ...

    Abstract Objective: We evaluated the accuracy of molecular breast imaging (MBI)-a nuclear medicine technique that employs dedicated dual-detector, cadmium zinc telluride gamma cameras to image the functional uptake of a radiopharmaceutical (typically Tc-99m sestamibi) in the breast-in patients with suspicious calcifications on mammography.
    Methods: Women scheduled for stereotactic biopsy of calcifications detected on 2D digital mammography were prospectively enrolled to undergo MBI before biopsy. Molecular breast imaging was performed with injection of Tc-99m sestamibi and a dual-detector, cadmium zinc telluride gamma camera. Positive findings on either modality were biopsied. High-risk and malignant biopsy findings were excised.
    Results: In 71 participants, 76 areas of calcifications were recommended for biopsy after mammography, and 24 (32%) were malignant, including 20 cases of ductal carcinoma in situ (DCIS) and 4 cases of invasive ductal cancer. Prebiopsy MBI was positive in 17 of the 76 (22%) calcifications, including 10 of 20 (50%) DCISs and 2 of 4 (50%) invasive cancers. The median pathologic size for MBI-positive cancers was 1.5 cm (range 0.5-3.2 cm) compared with 0.9 cm (range 0.1-2.0 cm) for MBI-negative cancers (P = 0.09).Non-mass uptake on MBI led to additional biopsies of 6 sites in 6 patients, and 2 of 6 (33%) MBI-detected incidental lesions showed malignancy; both DCIS contralateral to the mammographically detected calcifications. The overall per-lesion positive and negative predictive values of MBI in this prebiopsy setting were 61% (14 of 23) and 80% (47 of 59), respectively.
    Conclusion: Molecular breast imaging has insufficient negative predictive value to identify calcifications in which biopsy could be avoided. However, among women presenting for biopsy of suspicious calcifications, MBI revealed additional sites of mammographically occult breast cancer.To avoid biopsy of suspicious calcifications on mammography, negative findings on MBI should not be used.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbz054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Improving Prognostic Accuracy of Myocardial Perfusion Imaging With Quantitative Assessment.

    Miller, Todd D / O'Connor, Michael K

    JACC. Cardiovascular imaging

    2019  Volume 13, Issue 3, Page(s) 786–789

    MeSH term(s) Coronary Artery Disease/diagnostic imaging ; Humans ; Myocardial Perfusion Imaging ; Prognosis ; Tomography, Emission-Computed, Single-Photon
    Language English
    Publishing date 2019-06-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2491503-8
    ISSN 1876-7591 ; 1936-878X
    ISSN (online) 1876-7591
    ISSN 1936-878X
    DOI 10.1016/j.jcmg.2019.04.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The eventual rejection of the linear no-threshold theory will lead to a drastic reduction in the demand for diagnostic medical physics services.

    Jones, Aaron Kyle / O'Connor, Michael K / Zaidi, Habib

    Medical physics

    2019  Volume 46, Issue 8, Page(s) 3325–3328

    MeSH term(s) Diagnostic Techniques and Procedures/statistics & numerical data ; Health Physics ; Health Services Needs and Demand/statistics & numerical data ; Humans ; Linear Models ; Radiation Protection
    Language English
    Publishing date 2019-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 188780-4
    ISSN 2473-4209 ; 0094-2405
    ISSN (online) 2473-4209
    ISSN 0094-2405
    DOI 10.1002/mp.13619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Molecular Breast Imaging in Clinical Practice.

    Dibble, Elizabeth H / Hunt, Katie N / Ehman, Eric C / O'Connor, Michael K

    AJR. American journal of roentgenology

    2020  Volume 215, Issue 2, Page(s) 277–284

    Abstract: OBJECTIVE. ...

    Abstract OBJECTIVE.
    MeSH term(s) Breast Density ; Breast Neoplasms/diagnostic imaging ; Female ; Humans ; Molecular Imaging ; Radiation Injuries/epidemiology ; Risk Assessment
    Language English
    Publishing date 2020-06-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.19.22622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Detection of multicentric breast cancer using dedicated breast PET.

    Hunt, Katie N / Swanson, Tiffinee / O'Connor, Michael K / Sandhu, Nicole P

    The breast journal

    2019  Volume 25, Issue 3, Page(s) 512–514

    MeSH term(s) Aged ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Carcinoma, Ductal, Breast/diagnostic imaging ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Ductal, Breast/surgery ; Female ; Humans ; Magnetic Resonance Imaging ; Positron Emission Tomography Computed Tomography ; Positron-Emission Tomography/methods ; Ultrasonography, Mammary
    Language English
    Publishing date 2019-04-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1289960-4
    ISSN 1524-4741 ; 1075-122X
    ISSN (online) 1524-4741
    ISSN 1075-122X
    DOI 10.1111/tbj.13270
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Curies, and Grays, and Sieverts, Oh My: A Guide for Discussing Radiation Dose and Risk of Molecular Breast Imaging.

    Hruska, Carrie B / O'Connor, Michael K

    Journal of the American College of Radiology : JACR

    2015  Volume 12, Issue 10, Page(s) 1103–1105

    MeSH term(s) Absorption, Radiation ; Algorithms ; Breast Neoplasms/diagnostic imaging ; Female ; Humans ; Incidence ; Molecular Imaging/statistics & numerical data ; Neoplasms, Radiation-Induced/epidemiology ; Patient Education as Topic/methods ; Radiation Exposure/statistics & numerical data ; Radionuclide Imaging ; Risk Assessment/methods ; United States
    Language English
    Publishing date 2015-10
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2274861-1
    ISSN 1558-349X ; 1546-1440
    ISSN (online) 1558-349X
    ISSN 1546-1440
    DOI 10.1016/j.jacr.2015.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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