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  1. AU="O'Rourke, Dennis H"
  2. AU="Ozuna, César"
  3. AU="Vázquez-Carrera, Manuel"
  4. AU="Tanner, Rikki M"
  5. AU="Daniel H Miller"
  6. AU="Madec, Jean-Yves"
  7. AU=Rahimi Mitra

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  1. Buch: Genetics, evolution, and disease

    O'Rourke, Dennis H.

    a collection of papers from symposia from the fifty-first annual meeting of the American Assoc. of Physical Anthropologists, Eugene, Oregon, April 1 - 3, 1982

    1983  

    Körperschaft American Association of Physical Anthropologists
    Verfasserangabe ed. Dennis H. O'Rourke
    Schlagwörter Disease / etiology / congresses ; Evolution / congresses ; Genetics, Medical / congresses ; Genetics, Population / congresses ; Genetik ; Krankheit ; Evolution
    Schlagwörter Allgemeine Genetik ; Erbbiologie ; Erbforschung ; Erblehre ; Vererbungslehre ; Vererbungswissenschaft ; Erblichkeitslehre ; Abstammung ; Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos
    Sprache Englisch
    Umfang VIII, 127 S. : graph. Darst.
    Verlag Liss
    Erscheinungsort New York
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT003102457
    ISBN 0-8451-0227-3 ; 978-0-8451-0227-5
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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    1988 A 1879 bestellbar zur Ausleihe Magazin

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  2. Artikel ; Online: Peopling of the Americas: A new approach to assessing dental morphological variation in Asian and Native American populations.

    Scott, G Richard / Navega, David / Vlemincq-Mendieta, Tatiana / Dern, Laresa L / O'Rourke, Dennis H / Hlusko, Leslea J / Hoffecker, John F

    American journal of biological anthropology

    2023  

    Abstract: Objectives: Through biodistance analyses, anthropologists have used dental morphology to elucidate how people moved into and throughout the Americas. Here, we apply a method that focuses on individuals rather than sample frequencies through the ... ...

    Abstract Objectives: Through biodistance analyses, anthropologists have used dental morphology to elucidate how people moved into and throughout the Americas. Here, we apply a method that focuses on individuals rather than sample frequencies through the application rASUDAS2, based on a naïve Bayes' algorithm.
    Materials and methods: Using the database of C.G. Turner II, we calculated the probability that an individual could be assigned to one of seven biogeographic groups (American Arctic, North & South America, East Asia, Southeast Asia & Polynesia, Australo-Melanesia, Western Eurasia, & Sub-Saharan Africa) through rASUDAS2. The frequency of classifications for each biogeographic group was determined for 1418 individuals from six regions across Asia and the Americas.
    Results: Southeast Asians show mixed assignments but rarely to American Arctic or "American Indian." East Asians are assigned to East Asia half the time while 30% are assigned as Native American. People from the American Arctic and North & South America are assigned to Arctic America or non-Arctic America 75%-80% of the time, with 10%-15% classified as East Asian.
    Discussion: All Native American groups have a similar degree of morphological affinity to East Asia, as 10%-15% are classified as East Asian. East Asians are classified as Native American in 30% of cases. Individuals in the Western Hemisphere are decreasingly classified as Arctic the farther south they are located. Equivalent levels of classification as East Asian across all Native American groups suggests one divergence between East Asians and the population ancestral to all Native Americans. Non-arctic Native American groups are derived from the Arctic population, which represents the Native American founder group.
    Sprache Englisch
    Erscheinungsdatum 2023-11-28
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2692-7691
    ISSN (online) 2692-7691
    DOI 10.1002/ajpa.24878
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  3. Artikel ; Online: Molecular analysis of an ancient Thule population at Nuvuk, Point Barrow, Alaska.

    Tackney, Justin / Jensen, Anne M / Kisielinski, Caroline / O'Rourke, Dennis H

    American journal of physical anthropology

    2019  Band 168, Heft 2, Seite(n) 303–317

    Abstract: Objectives: The North American archaeological record supports a Holocene origin of Arctic Indigenous peoples. Although the Paleo-Inuit were present for millennia, archaeological and genetic studies suggest that modern peoples descend from a second, more ...

    Abstract Objectives: The North American archaeological record supports a Holocene origin of Arctic Indigenous peoples. Although the Paleo-Inuit were present for millennia, archaeological and genetic studies suggest that modern peoples descend from a second, more recent tradition known as the Neo-Inuit. Origins of the Neo-Inuit and their relations to the earlier and later Indigenous peoples are an area of active study. Here, we genetically analyze the maternal lineages present at Nuvuk, once the northernmost community in Alaska and located in a region identified as a possible origin point of the Neo-Inuit Thule. The cemetery at Nuvuk contains human remains representing a nearly one thousand year uninterrupted occupation from early Thule to post-contact Iñupiat.
    Materials and methods: We selected 44 individuals from Nuvuk with calibrated dates between 981 AD and 1885 AD for molecular analysis. We amplified and sequenced the hypervariable segment I of the mitogenome. We compared the Nuvuk data with previously published sequences from 68 modern and ancient communities from across Asia and North America. Phylogeographic analyses suggest possible scenarios of Holocene Arctic and sub-Arctic population movements.
    Results: We successfully retrieved sequence data from 39 individuals. Haplogroup frequencies in Nuvuk were typed as 66.7% A2b1, 25.6% A2a, and 7.7% D4b1a2a1a. These results suggest that the population at Nuvuk was closest to the ancient Thule and modern Inuit of Canada, and to the Siberian Naukan people. We confirm that haplogroups A2a, A2b1, D2a, and D4b1a2a1a appear at high frequency in Arctic and sub-Arctic populations of North America and Chukotka. Sister clades D2b and D4b1a2a1b are present in Asian and Eastern European populations.
    Discussion: The ancient mitochondrial sequences from Nuvuk confirm the link between the North Slope and the Thule who later spread east, and the maternal discontinuity between the Neo-Inuit and Paleo-Inuit. We suggest haplogroups A2a, A2b, and D4b1a2a1a are linked to the ancestors of the Thule in eastern Beringia, whereas the D2 and D4b1a2a1 clades appear to have Asian Holocene origins. Further Siberian and Alaskan genomes are necessary to clarify these population migrations beyond a simple two-wave scenario of Neo-Inuit and Paleo-Inuit.
    Mesh-Begriff(e) Alaska ; Anthropology, Physical ; Arctic Regions ; DNA, Ancient/analysis ; DNA, Mitochondrial/genetics ; Haplotypes/genetics ; History, 15th Century ; History, 16th Century ; History, 17th Century ; History, 18th Century ; History, 19th Century ; History, Medieval ; Humans ; Inuits/genetics ; Inuits/history ; Phylogeography
    Chemische Substanzen DNA, Ancient ; DNA, Mitochondrial
    Sprache Englisch
    Erscheinungsdatum 2019-01-10
    Erscheinungsland United States
    Dokumenttyp Historical Article ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 219376-0
    ISSN 1096-8644 ; 0002-9483
    ISSN (online) 1096-8644
    ISSN 0002-9483
    DOI 10.1002/ajpa.23746
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Beringia and the peopling of the Western Hemisphere.

    Hoffecker, John F / Elias, Scott A / Scott, G Richard / O'Rourke, Dennis H / Hlusko, Leslea J / Potapova, Olga / Pitulko, Vladimir / Pavlova, Elena / Bourgeon, Lauriane / Vachula, Richard S

    Proceedings. Biological sciences

    2023  Band 290, Heft 1990, Seite(n) 20222246

    Abstract: Did Beringian environments represent ... ...

    Abstract Did Beringian environments represent an
    Mesh-Begriff(e) Animals ; Humans ; North America ; Americas ; Arctic Regions ; Mammals
    Sprache Englisch
    Erscheinungsdatum 2023-01-11
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 209242-6
    ISSN 1471-2954 ; 0080-4649 ; 0962-8452 ; 0950-1193
    ISSN (online) 1471-2954
    ISSN 0080-4649 ; 0962-8452 ; 0950-1193
    DOI 10.1098/rspb.2022.2246
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: World variation in three-rooted lower second molars and implications for the hominin fossil record.

    Scott, G Richard / Dern, Laresa L / Pastore, Arielle J / Sullivan, Mackenzie R / Nesbitt, Heather / O'Rourke, Dennis H / Irish, Joel D / Hoffecker, John F

    Journal of human evolution

    2023  Band 177, Seite(n) 103327

    Mesh-Begriff(e) Animals ; Hominidae ; Fossils ; Molar ; Biological Evolution
    Sprache Englisch
    Erscheinungsdatum 2023-02-24
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 120141-4
    ISSN 1095-8606 ; 0047-2484
    ISSN (online) 1095-8606
    ISSN 0047-2484
    DOI 10.1016/j.jhevol.2023.103327
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  6. Artikel ; Online: Human migrations: the two roads taken.

    O'Rourke, Dennis H

    Current biology : CB

    2009  Band 19, Heft 5, Seite(n) R203–5

    Abstract: America was peopled from Asia by at least the end of the last ice age, but the exact timing of entry and the composition of the source population are unclear. A new analysis of two rare mitochondrial haplogroups suggests two separate Asian migrations ... ...

    Abstract America was peopled from Asia by at least the end of the last ice age, but the exact timing of entry and the composition of the source population are unclear. A new analysis of two rare mitochondrial haplogroups suggests two separate Asian migrations into the Americas, indicating simultaneous but independent Asian source populations for early American colonists.
    Mesh-Begriff(e) Americas ; Asia ; DNA, Mitochondrial/genetics ; Emigration and Immigration ; Evolution, Molecular ; Gene Frequency ; Genetic Variation ; Geography ; Humans ; Sequence Analysis, DNA
    Chemische Substanzen DNA, Mitochondrial
    Sprache Englisch
    Erscheinungsdatum 2009-03-10
    Erscheinungsland England
    Dokumenttyp Comment ; Journal Article
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2009.01.021
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  7. Artikel ; Online: Inbreeding, heterozygosity, and lymphoma risk among the baboons (Papio hamadryas) of Sukhumi, USSR.

    Crawford, Michael H / O'Rourke, Dennis H / Dykes, Dale D / Yakovleva, L A / Voevodin, A F / Lapin, Boris / Polesky, H F

    American journal of primatology

    2020  Band 6, Heft 3, Seite(n) 143–153

    Abstract: This paper describes the spread of lymphoma through a baboon (Papio hamadryas) colony in the Institute of Experimental Pathology and Therapy at Sukhumi, USSR. In the late 1960s, Soviet scientists inoculated 12 baboons with cells from hospitalized human ... ...

    Abstract This paper describes the spread of lymphoma through a baboon (Papio hamadryas) colony in the Institute of Experimental Pathology and Therapy at Sukhumi, USSR. In the late 1960s, Soviet scientists inoculated 12 baboons with cells from hospitalized human leukemia patients, causing the death of a total of 135 animals between 1967 and 1978. The death rate from lymphoma averages almost 12 baboons per year in the Sukhumi colony. Genetic investigations of these baboons revealed the following: 1) Six blood protein markers out of 16 systems (38%) tested were polymorphic; 2) the average inbreeding coefficient for the entire colony (N = 1,226) was 0.027 (exclusion of baboons with F values equal to 0.0 raised the mean inbreeding coefficient to 0.096); 3) no relationship between inbreeding and risk of lymphoma was noted; and 4) there was an apparent association between both PGM loci and the incidence of lymphoma at the 0.005 levels of significance. This association was further supported by the significantly lower incidence of PGM2 (2-1) genotype in baboons with high anti-VCA-HVP titers.
    Sprache Englisch
    Erscheinungsdatum 2020-01-18
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1495834-X
    ISSN 1098-2345 ; 0275-2565
    ISSN (online) 1098-2345
    ISSN 0275-2565
    DOI 10.1002/ajp.1350060303
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  8. Buch: Human biology

    Stinson, Sara / Bogin, Barry / O'Rourke, Dennis H

    an evolutionary and biocultural perspective

    2012  

    Abstract: The book covers all the major areas of human biology: Genetic variation, variation related to climate, infectious and non-infectious diseases, aging, growth, nutrition, and demography. All chapters are authored by leading experts in the field. ... ...

    Verfasserangabe edited by Sara Stinson, Barry Bogin, Dennis O'Rourke
    Abstract "The book covers all the major areas of human biology: Genetic variation, variation related to climate, infectious and non-infectious diseases, aging, growth, nutrition, and demography. All chapters are authored by leading experts in the field. Extensively rewritten by the four authors working in close collaboration for consistent style and format, the new edition of this best-selling book also features two new chapters, one on race and culture and their ties to human biology, and the other a concluding summary chapter highlighting the integration and intersection of the topics covered in the book"--
    Mesh-Begriff(e) Biological Evolution ; Anthropology, Physical
    Sprache Englisch
    Umfang x, 863 p. :, ill. ;, 27 cm.
    Ausgabenhinweis 2nd ed.
    Verlag Wiley-Blackwell
    Erscheinungsort Hoboken, NJ
    Dokumenttyp Buch
    Anmerkung Machine generated contents note: Introduction.Chapter 1. Human Biology: An Evolutionary and Biocultural Perspective (Sara Stinson, Barry Bogin, Dennis O'Rourke, and Rebecca Huss-Ashmore).Chapter 2. History of Human Biology in the United States of America (Francis E. Johnston and Michael A. Little).Heredity and Patterned Human Variation.Chapter 3. An Introduction to Genetics (Mark Weiss and Justin Tackney).Chapter 4. Genetics, Geography, and Human Variation (Dennis O'Rourke and Jake Enk).Chapter 5. Quantitative Variation and Genetics (Lyle Konigsberg).Human Adaptability.Chapter 6. Human Adaptation to Climate: Temperature, Ultraviolet Radiation and Altitude (Cynthia M. Beall, Nina Jablonski, and A. Theordore Steegmann, Jr.).Chapter 7. Evolution of Human Nutrition (William R. Leonard).Chapter 8. Human Energetics (J. Josh Snodgrass).Human Biology and Health.Chapter 9. The Epidemiology of Human Disease (Lisa Sattenspiel and Karen Slonim).Chapter 10. Stress and Human Biology (Gillian H. Ice and Gary D. James).The Human Life Course.Chapter 11. Evolution of the Human Life Cycle (Barry Bogin and B. Holly Smith).Chapter 12. Growth Variation: Biological and Cultural Factors (Sara Stinson).Chapter 13. Aging, Senescence and Human Variation (Douglas E. Crews and Gillian Ice).Population Dynamics.Chapter 14. Demography, Part 1: Mortality and Migration( Timothy B. Gage, Sharon N. DeWitte, and James W. Wood).Chapter 15. Demography, Part 2: Population Growth and Fertility Regulation (Peter T. Ellison, Barry Bogin, and Mary O'Rourke).
    ISBN 9780470179642 ; 0470179643
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  9. Artikel ; Online: Anthropology. Out of Beringia?

    Hoffecker, John F / Elias, Scott A / O'Rourke, Dennis H

    Science (New York, N.Y.)

    2014  Band 343, Heft 6174, Seite(n) 979–980

    Mesh-Begriff(e) Alaska ; Anthropology ; DNA, Mitochondrial/genetics ; Human Migration ; Humans ; Ice Cover ; Indians, North American/genetics ; Islands ; North America ; Oceans and Seas ; Reproductive Isolation ; Trees
    Chemische Substanzen DNA, Mitochondrial
    Sprache Englisch
    Erscheinungsdatum 2014-02-28
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.1250768
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  10. Artikel ; Online: Beringia and the global dispersal of modern humans.

    Hoffecker, John F / Elias, Scott A / O'Rourke, Dennis H / Scott, G Richard / Bigelow, Nancy H

    Evolutionary anthropology

    2016  Band 25, Heft 2, Seite(n) 64–78

    Abstract: Until recently, the settlement of the Americas seemed largely divorced from the out-of-Africa dispersal of anatomically modern humans, which began at least 50,000 years ago. Native Americans were thought to represent a small subset of the Eurasian ... ...

    Abstract Until recently, the settlement of the Americas seemed largely divorced from the out-of-Africa dispersal of anatomically modern humans, which began at least 50,000 years ago. Native Americans were thought to represent a small subset of the Eurasian population that migrated to the Western Hemisphere less than 15,000 years ago. Archeological discoveries since 2000 reveal, however, that Homo sapiens occupied the high-latitude region between Northeast Asia and northwest North America (that is, Beringia) before 30,000 years ago and the Last Glacial Maximum (LGM). The settlement of Beringia now appears to have been part of modern human dispersal in northern Eurasia. A 2007 model, the Beringian Standstill Hypothesis, which is based on analysis of mitochondrial DNA (mtDNA) in living people, derives Native Americans from a population that occupied Beringia during the LGM. The model suggests a parallel between ancestral Native Americans and modern human populations that retreated to refugia in other parts of the world during the arid LGM. It is supported by evidence of comparatively mild climates and rich biota in south-central Beringia at this time (30,000-15,000 years ago). These and other developments suggest that the settlement of the Americas may be integrated with the global dispersal of modern humans.
    Mesh-Begriff(e) Asia ; Biological Evolution ; Climate ; History, Ancient ; Human Migration/history ; Humans ; Models, Theoretical ; North America
    Sprache Englisch
    Erscheinungsdatum 2016-03
    Erscheinungsland United States
    Dokumenttyp Historical Article ; Journal Article
    ZDB-ID 1492309-9
    ISSN 1520-6505 ; 1060-1538
    ISSN (online) 1520-6505
    ISSN 1060-1538
    DOI 10.1002/evan.21478
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