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  1. Article: Editorial: Novel aspects of the immunological and structural barrier of the epidermis.

    O'Shaughnessy, Ryan / Common, John / Gutowska-Owsiak, Danuta

    Frontiers in molecular biosciences

    2023  Volume 10, Page(s) 1324920

    Language English
    Publishing date 2023-11-01
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2023.1324920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ceramide kinase-like protein, 'the kinase that isn't', finds a role in skin cancer stress relief.

    O'Shaughnessy, R F L

    The British journal of dermatology

    2021  Volume 185, Issue 1, Page(s) 14–15

    MeSH term(s) Humans ; Mitogen-Activated Protein Kinases ; Phosphotransferases (Alcohol Group Acceptor) ; Skin Neoplasms/drug therapy
    Chemical Substances Phosphotransferases (Alcohol Group Acceptor) (EC 2.7.1.-) ; ceramide kinase (EC 2.7.1.138) ; Mitogen-Activated Protein Kinases (EC 2.7.11.24)
    Language English
    Publishing date 2021-03-23
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.19888
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  3. Article ; Online: Understanding the paradoxical proinflammatory effects of an immunosuppressant.

    O'Shaughnessy, R F L

    The British journal of dermatology

    2021  Volume 185, Issue 6, Page(s) 1091–1092

    MeSH term(s) Humans ; Immunosuppressive Agents/adverse effects
    Chemical Substances Immunosuppressive Agents
    Language English
    Publishing date 2021-11-08
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.20778
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  4. Article ; Online: Ubiquitin, a novel therapeutic target in psoriasis?

    O'Shaughnessy, R F L

    The British journal of dermatology

    2020  Volume 184, Issue 1, Page(s) 8–9

    MeSH term(s) Epidermis ; Humans ; Inflammation ; Keratinocytes ; NF-kappa B ; Psoriasis/drug therapy ; Ubiquitin ; Ubiquitin-Protein Ligases
    Chemical Substances NF-kappa B ; Ubiquitin ; Ubiquitin-Protein Ligases (EC 2.3.2.27)
    Language English
    Publishing date 2020-07-21
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.19332
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  5. Article ; Online: Targeting tryptophan transport and breakdown in basal cell carcinoma.

    O'Shaughnessy, R F L

    The British journal of dermatology

    2019  Volume 180, Issue 1, Page(s) 16–17

    MeSH term(s) Amino Acid Transport Systems ; Carcinoma, Basal Cell ; Fusion Regulatory Protein 1, Light Chains ; Humans ; Large Neutral Amino Acid-Transporter 1 ; Skin Neoplasms ; Tryptophan
    Chemical Substances Amino Acid Transport Systems ; Fusion Regulatory Protein 1, Light Chains ; Large Neutral Amino Acid-Transporter 1 ; SLC7A7 protein, human ; Tryptophan (8DUH1N11BX)
    Language English
    Publishing date 2019-01-02
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.17316
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  6. Article ; Online: Understanding actinic keratosis to reduce squamous cell carcinoma incidence.

    O'Shaughnessy, R F L

    The British journal of dermatology

    2019  Volume 182, Issue 4, Page(s) 834–835

    MeSH term(s) Carcinoma, Squamous Cell ; Humans ; Incidence ; Keratosis, Actinic ; Skin Neoplasms
    Language English
    Publishing date 2019-10-16
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.18529
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  7. Article ; Online: Becoming a mother in the context of sex work: Women's experiences of bonding with their children.

    Elsdon, Ruth / O'Shaughnessy, Ruth / Hodge, Suzanne M / Murray, Craig D

    Health care for women international

    2021  Volume 43, Issue 6, Page(s) 663–685

    Abstract: Many females engaged in sex work are mothers, often experiencing poverty, violence, marginalization, and psychological distress, factors also found to affect parental bonds. However, little is known about how this context impacts the bonding process. ... ...

    Abstract Many females engaged in sex work are mothers, often experiencing poverty, violence, marginalization, and psychological distress, factors also found to affect parental bonds. However, little is known about how this context impacts the bonding process. Given the ubiquity of sex work across geographical territories, understanding the relationship it has with mother-child bonding is an important international consideration in providing healthcare for sex working mothers and their children. Therefore, in this study we sought to explore women's experiences of bonding with their children in the context of sex work. We interviewed six women in the UK who were sex working during the first two years of their child's life about their bonding experiences and analyzed transcripts using Interpretative Phenomenological Analysis. We identified four themes were identified: (1) the complex process of bonding; (2) the role of powerlessness on bonding; (3) the powerful impact of receiving help, and (4) new perspectives of the body and sex work following motherhood. Findings contribute to the research literature on bonding by emphasizing the value of supportive care and the importance of social context, indicating specific factors to inform psychological support among sex working women.
    MeSH term(s) Female ; Humans ; Mothers/psychology ; Parents ; Poverty ; Sex Work ; Women, Working
    Language English
    Publishing date 2021-08-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 632677-8
    ISSN 1096-4665 ; 0739-9332
    ISSN (online) 1096-4665
    ISSN 0739-9332
    DOI 10.1080/07399332.2021.1949598
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    Zs.B 2847: Show issues Location:
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  8. Article ; Online: Commentary: Phallometry in Court—Problems Outweigh Benefits.

    O'Shaughnessy, Roy

    The journal of the American Academy of Psychiatry and the Law

    2015  Volume 43, Issue 2, Page(s) 154–158

    Abstract: Phallometry evaluations are of great value in sex offender treatment programs, in assessing for a deviant drive related to criminal offenses and in monitoring treatment results, especially in connection with cognitive behavioral techniques that teach ... ...

    Abstract Phallometry evaluations are of great value in sex offender treatment programs, in assessing for a deviant drive related to criminal offenses and in monitoring treatment results, especially in connection with cognitive behavioral techniques that teach skills for reducing deviant sexual interests. The research on phallometry, however, is fraught with methodological problems that limit its utility in settings such as court procedures where there is a strong self-interest in producing results that suggest the absence of deviant sexual drives. The lack of consensus in methodology and scoring, the difficulty encountered in "nonadmitters," the ability to dissimulate ("fake good") on the assessments, and the lack of good specificity and sensitivity data limit the use of such procedures in any setting that could affect length of sentence or determination of civil commitment.
    MeSH term(s) Criminal Law/legislation & jurisprudence ; Expert Testimony/legislation & jurisprudence ; Humans ; Informed Consent/legislation & jurisprudence ; Male ; Paraphilic Disorders/diagnosis ; Paraphilic Disorders/rehabilitation ; Penile Erection ; Plethysmography ; Sex Offenses/legislation & jurisprudence
    Language English
    Publishing date 2015-06
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 1381489-8
    ISSN 1943-3662 ; 0091-634X ; 1093-6793
    ISSN (online) 1943-3662
    ISSN 0091-634X ; 1093-6793
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  9. Article ; Online: PLCD1 and Pilar Cysts.

    Shimomura, Yutaka / O'Shaughnessy, Ryan / Rajan, Neil

    The Journal of investigative dermatology

    2018  Volume 139, Issue 10, Page(s) 2075–2077

    Abstract: Trichilemmal or "pilar" cysts are commonly found on the scalp and are derived from the outer root sheath of the hair follicle. Multiple trichilemmal cysts present in an autosomal dominant pattern of inheritance, yet the genetic mechanism has remained ... ...

    Abstract Trichilemmal or "pilar" cysts are commonly found on the scalp and are derived from the outer root sheath of the hair follicle. Multiple trichilemmal cysts present in an autosomal dominant pattern of inheritance, yet the genetic mechanism has remained elusive. In this issue, Hörer et al. (2019) highlight predisposing variants in PLCD1 in such families and propose a monoallelic mutational mechanism that drives cyst formation.
    MeSH term(s) Epidermal Cyst ; Hair Follicle ; Humans ; Phospholipase C delta ; Scalp
    Chemical Substances PLCD1 protein, human (EC 3.1.4.11) ; Phospholipase C delta (EC 3.1.4.11)
    Language English
    Publishing date 2018-10-25
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80136-7
    ISSN 1523-1747 ; 0022-202X
    ISSN (online) 1523-1747
    ISSN 0022-202X
    DOI 10.1016/j.jid.2019.05.027
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  10. Article ; Online: Anisotropies in the Astrophysical Gravitational-Wave Background: The Impact of Black Hole Distributions.

    Jenkins, Alexander C / O'Shaughnessy, Richard / Sakellariadou, Mairi / Wysocki, Daniel

    Physical review letters

    2019  Volume 122, Issue 11, Page(s) 111101

    Abstract: We use population inference to explore the impact that uncertainties in the distribution of binary black holes (BBH) have on the astrophysical gravitational-wave background (AGWB). Our results show that the AGWB monopole is sensitive to the nature of the ...

    Abstract We use population inference to explore the impact that uncertainties in the distribution of binary black holes (BBH) have on the astrophysical gravitational-wave background (AGWB). Our results show that the AGWB monopole is sensitive to the nature of the BBH population (particularly the local merger rate), while the anisotropic C_{ℓ} spectrum is only modified to within a few percent, at a level which is insignificant compared to other sources of uncertainty (such as cosmic variance). This is very promising news for future observational studies of the AGWB, as it shows that (i) the monopole can be used as a new probe of the population of compact objects throughout cosmic history, complementary to direct observations by LIGO and Virgo and (ii) we are able to make surprisingly robust predictions for the C_{ℓ} spectrum, even with only very approximate knowledge of the black hole population. As a result, the AGWB anisotropies have enormous potential as a new probe of the large-scale structure of the Universe, and of late-Universe cosmology in general.
    Language English
    Publishing date 2019-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.122.111101
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