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  1. Article: Comparative genomics of the coxsackie B viruses and related enteroviruses.

    Oberste, M S

    Current topics in microbiology and immunology

    2007  Volume 323, Page(s) 33–47

    Abstract: Genomic analysis of the group B coxsackieviruses (CVB) has improved our understanding of CVB evolution, epidemiology, and pathogenesis. Comparison of capsid sequence alignments and virion structures allows correlation of capsid diversity with surface ... ...

    Abstract Genomic analysis of the group B coxsackieviruses (CVB) has improved our understanding of CVB evolution, epidemiology, and pathogenesis. Comparison of capsid sequence alignments and virion structures allows correlation of capsid diversity with surface features, such as loops, the receptor canyon, and antigenic sites. Pairwise sequence comparisons and phylogenetic analyses can be used to rapidly identify and classify enteroviruses. Enteroviruses are monophyletic by type only within the capsid region. The CVBs as a group are monophyletic in the capsid region, probably due to their shared use of the coxsackievirus-adenovirus receptor (other members of HEV-B use different receptors). Outside the capsid region, enteroviruses are monophyletic only by species (not by type), reflecting a high frequency of intertypic recombination within a species. Further genomic studies, accompanied by well-characterized clinical outcome/disease data, will facilitate fine-scale mapping of genetic determinants that contribute to virulence.
    MeSH term(s) Capsid ; Capsid Proteins/genetics ; Enterovirus/genetics ; Enterovirus B, Human/classification ; Enterovirus B, Human/genetics ; Genetic Variation ; Genome, Viral ; Genomics ; Humans ; Phylogeny ; Untranslated Regions ; Viral Proteins/genetics ; Viral Proteins/metabolism
    Chemical Substances Capsid Proteins ; Untranslated Regions ; Viral Proteins
    Language English
    Publishing date 2007-11-06
    Publishing country Germany
    Document type Comparative Study ; Journal Article ; Review
    ISSN 0070-217X
    ISSN 0070-217X
    DOI 10.1007/978-3-540-75546-3_2
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  2. Article ; Online: Correction to: Recommendations for the nomenclature of enteroviruses and rhinoviruses.

    Simmonds, P / Gorbalenya, A E / Harvala, H / Hovi, T / Knowles, N J / Lindberg, A M / Oberste, M S / Palmenberg, A C / Reuter, G / Skern, T / Tapparel, C / Wolthers, K C / Woo, P C Y / Zell, R

    Archives of virology

    2020  Volume 165, Issue 6, Page(s) 1515

    Abstract: Unfortunately, one of the affiliations of author "A. E. Gorbalenya" was missed in original version. The affiliation is updated here. ...

    Abstract Unfortunately, one of the affiliations of author "A. E. Gorbalenya" was missed in original version. The affiliation is updated here.
    Language English
    Publishing date 2020-03-23
    Publishing country Austria
    Document type Journal Article ; Published Erratum
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-020-04558-x
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  3. Article: Recommendations for the nomenclature of enteroviruses and rhinoviruses [Erratum: Jun. 2020, v.165(6), p.1515]

    Simmonds, P / Gorbalenya, A. E / Harvala, H / Hovi, T / Knowles, N. J / Lindberg, A. M / Oberste, M. S / Palmenberg, A. C / Reuter, G / Skern, T / Tapparel, C / Wolthers, K. C / Woo, P. C. Y / Zell, R

    Archives of virology. 2020 Mar., v. 165, no. 3

    2020  

    Abstract: Enteroviruses (EVs) and rhinoviruses (RVs) are significant pathogens of humans and are the subject of intensive clinical and epidemiological research and public health measures, notably in the eradication of poliovirus and in the investigation and ... ...

    Abstract Enteroviruses (EVs) and rhinoviruses (RVs) are significant pathogens of humans and are the subject of intensive clinical and epidemiological research and public health measures, notably in the eradication of poliovirus and in the investigation and control of emerging pathogenic EV types worldwide. EVs and RVs are highly diverse in their antigenic properties, tissue tropism, disease associations and evolutionary relationships, but the latter often conflict with previously developed biologically defined terms, such as “coxsackieviruses”, “polioviruses” and “echoviruses”, which were used before their genetic interrelationships were understood. This has created widespread formatting problems and inconsistencies in the nomenclature for EV and RV types and species in the literature and public databases. As members of the International Committee for Taxonomy of Viruses (ICTV) Picornaviridae Study Group, we describe the correct use of taxon names for these viruses and have produced a series of recommendations for the nomenclature of EV and RV types and their abbreviations. We believe their adoption will promote greater clarity and consistency in the terminology used in the scientific and medical literature. The recommendations will additionally provide a useful reference guide for journals, other publications and public databases seeking to use standardised terms for the growing multitude of enteroviruses and rhinoviruses described worldwide.
    Keywords public health ; taxonomy ; terminology ; tissue tropism ; virology
    Language English
    Dates of publication 2020-03
    Size p. 793-797.
    Publishing place Springer Vienna
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-019-04520-6
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  4. Article: Seven Strains of Enterovirus D68 Detected in the United States during the 2014 Severe Respiratory Disease Outbreak

    Brown, B. A / Nix, W. A / Sheth, M / Frace, M / Oberste, M. S

    Genome announcements. 2014 Dec. 24, v. 2, no. 6

    2014  

    Abstract: Clusters of severe respiratory disease in the United States were reported to the CDC beginning in August 2014. Enterovirus D68 (EV-D68) was identified from 83% (30/36) of initial severe cases. Investigations in August and September found severe EV-D68 ... ...

    Abstract Clusters of severe respiratory disease in the United States were reported to the CDC beginning in August 2014. Enterovirus D68 (EV-D68) was identified from 83% (30/36) of initial severe cases. Investigations in August and September found severe EV-D68 cases to be widespread across the United States. We report seven EV-D68 genomes from the outbreak.
    Keywords Enterovirus ; disease outbreaks ; genome ; respiratory tract diseases ; United States
    Language English
    Dates of publication 2014-1224
    Size p. e01201-14.
    Publishing place American Society for Microbiology
    Document type Article
    ZDB-ID 2704277-7
    ISSN 2169-8287
    ISSN 2169-8287
    DOI 10.1128/genomeA.01201-14
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  5. Article: Enteroviruses as agents of emerging infectious diseases.

    Palacios, G / Oberste, M S

    Journal of neurovirology

    2005  Volume 11, Issue 5, Page(s) 424–433

    Abstract: Although the enteroviruses as a group are ubiquitous and not normally considered as "emerging pathogens," the many different serotypes circulate at different frequencies in any given year and the prevalence of a given serotype may fluctuate wildly from ... ...

    Abstract Although the enteroviruses as a group are ubiquitous and not normally considered as "emerging pathogens," the many different serotypes circulate at different frequencies in any given year and the prevalence of a given serotype may fluctuate wildly from year to year. As a result, several enterovirus serotypes have been associated with the emergence of specific diseases (for example, pandemic acute hemorrhagic conjunctivitis) and specific serotypes have emerged to cause outbreaks of major public health concern. Enterovirus 71 is a recognized cause of epidemic severe central nervous system disease in Southeast Asia. Acute hemorrhagic conjunctivitis was a newly described disease in the 1970s associated with emergence of enterovirus 70 and coxsackievirus A24 variant. In addition, the impending eradication of poliovirus and some of the challenges currently faced by the eradication program present the possibility that poliomyelitis could emerge in the posteradication era. These links between enterovirus infections and emerging diseases are reviewed.
    MeSH term(s) Animals ; Communicable Diseases, Emerging/epidemiology ; Communicable Diseases, Emerging/virology ; Conjunctivitis, Acute Hemorrhagic/epidemiology ; Conjunctivitis, Acute Hemorrhagic/virology ; Disease Outbreaks ; Disease Reservoirs ; Enterovirus/classification ; Enterovirus/genetics ; Enterovirus/isolation & purification ; Enterovirus C, Human/isolation & purification ; Enterovirus D, Human/isolation & purification ; Enterovirus Infections/epidemiology ; Enterovirus Infections/virology ; Global Health ; Humans ; Molecular Epidemiology ; Poliomyelitis/epidemiology ; Poliomyelitis/virology ; Poliovirus/isolation & purification ; RNA, Viral/genetics ; Species Specificity ; Swine Vesicular Disease/epidemiology ; Swine Vesicular Disease/virology
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2005-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1283265-0
    ISSN 1538-2443 ; 1355-0284
    ISSN (online) 1538-2443
    ISSN 1355-0284
    DOI 10.1080/13550280591002531
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4426: Show issues Location:
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  6. Article: Seven Strains of Enterovirus D68 Detected in the United States during the 2014 Severe Respiratory Disease Outbreak.

    Brown, B A / Nix, W A / Sheth, M / Frace, M / Oberste, M S

    Genome announcements

    2014  Volume 2, Issue 6

    Abstract: Clusters of severe respiratory disease in the United States were reported to the CDC beginning in August 2014. Enterovirus D68 (EV-D68) was identified from 83% (30/36) of initial severe cases. Investigations in August and September found severe EV-D68 ... ...

    Abstract Clusters of severe respiratory disease in the United States were reported to the CDC beginning in August 2014. Enterovirus D68 (EV-D68) was identified from 83% (30/36) of initial severe cases. Investigations in August and September found severe EV-D68 cases to be widespread across the United States. We report seven EV-D68 genomes from the outbreak.
    Language English
    Publishing date 2014-11-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2704277-7
    ISSN 2169-8287
    ISSN 2169-8287
    DOI 10.1128/genomeA.01201-14
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  7. Article ; Online: Recommendations for the nomenclature of enteroviruses and rhinoviruses.

    Simmonds, P / Gorbalenya, A E / Harvala, H / Hovi, T / Knowles, N J / Lindberg, A M / Oberste, M S / Palmenberg, A C / Reuter, G / Skern, T / Tapparel, C / Wolthers, K C / Woo, P C Y / Zell, R

    Archives of virology

    2019  Volume 165, Issue 3, Page(s) 793–797

    Abstract: Enteroviruses (EVs) and rhinoviruses (RVs) are significant pathogens of humans and are the subject of intensive clinical and epidemiological research and public health measures, notably in the eradication of poliovirus and in the investigation and ... ...

    Abstract Enteroviruses (EVs) and rhinoviruses (RVs) are significant pathogens of humans and are the subject of intensive clinical and epidemiological research and public health measures, notably in the eradication of poliovirus and in the investigation and control of emerging pathogenic EV types worldwide. EVs and RVs are highly diverse in their antigenic properties, tissue tropism, disease associations and evolutionary relationships, but the latter often conflict with previously developed biologically defined terms, such as "coxsackieviruses", "polioviruses" and "echoviruses", which were used before their genetic interrelationships were understood. This has created widespread formatting problems and inconsistencies in the nomenclature for EV and RV types and species in the literature and public databases. As members of the International Committee for Taxonomy of Viruses (ICTV) Picornaviridae Study Group, we describe the correct use of taxon names for these viruses and have produced a series of recommendations for the nomenclature of EV and RV types and their abbreviations. We believe their adoption will promote greater clarity and consistency in the terminology used in the scientific and medical literature. The recommendations will additionally provide a useful reference guide for journals, other publications and public databases seeking to use standardised terms for the growing multitude of enteroviruses and rhinoviruses described worldwide.
    MeSH term(s) Enterovirus/classification ; Humans ; Rhinovirus/classification ; Terminology as Topic
    Language English
    Publishing date 2019-12-26
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-019-04520-6
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  8. Article: The complete genome sequence for an American isolate of enterovirus 77.

    Oberste, M S / Maher, K / Patterson, M A / Pallansch, M A

    Archives of virology

    2007  Volume 152, Issue 8, Page(s) 1587–1591

    MeSH term(s) Animals ; Cell Line ; Encephalitis, Viral/epidemiology ; Encephalitis, Viral/virology ; Enterovirus/classification ; Enterovirus/genetics ; Enterovirus/isolation & purification ; Enterovirus Infections/epidemiology ; Enterovirus Infections/virology ; Female ; Genome, Viral ; Humans ; Infant ; Molecular Sequence Data ; Phylogeny ; Sequence Analysis, DNA ; Texas/epidemiology
    Language English
    Publishing date 2007
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-007-0978-1
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  9. Article: The complete genome sequence for an American isolate of enterovirus 77

    Oberste, M. S / Maher, K / Patterson, M. A / Pallansch, M. A

    Archives of virology. 2007 Aug., v. 152, no. 8

    2007  

    Language English
    Dates of publication 2007-08
    Size p. 1587-1591.
    Publisher Springer-Verlag
    Publishing place Vienna
    Document type Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-007-0978-1
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    In stock of ZB MED Bonn / Germany

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  10. Article ; Online: An automated genotyping tool for enteroviruses and noroviruses.

    Kroneman, A / Vennema, H / Deforche, K / v d Avoort, H / Peñaranda, S / Oberste, M S / Vinjé, J / Koopmans, M

    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

    2011  Volume 51, Issue 2, Page(s) 121–125

    Abstract: Background: Molecular techniques are established as routine in virological laboratories and virus typing through (partial) sequence analysis is increasingly common. Quality assurance for the use of typing data requires harmonization of genotype ... ...

    Abstract Background: Molecular techniques are established as routine in virological laboratories and virus typing through (partial) sequence analysis is increasingly common. Quality assurance for the use of typing data requires harmonization of genotype nomenclature, and agreement on target genes, depending on the level of resolution required, and robustness of methods.
    Objective: To develop and validate web-based open-access typing-tools for enteroviruses and noroviruses.
    Study design: An automated web-based typing algorithm was developed, starting with BLAST analysis of the query sequence against a reference set of sequences from viruses in the family Picornaviridae or Caliciviridae. The second step is phylogenetic analysis of the query sequence and a sub-set of the reference sequences, to assign the enterovirus type or norovirus genotype and/or variant, with profile alignment, construction of phylogenetic trees and bootstrap validation. Typing is performed on VP1 sequences of Human enterovirus A to D, and ORF1 and ORF2 sequences of genogroup I and II noroviruses. For validation, we used the tools to automatically type sequences in the RIVM and CDC enterovirus databases and the FBVE norovirus database.
    Results: Using the typing-tools, 785(99%) of 795 Enterovirus VP1 sequences, and 8154(98.5%) of 8342 norovirus sequences were typed in accordance with previously used methods. Subtyping into variants was achieved for 4439(78.4%) of 5838 NoV GII.4 sequences.
    Discussion and conclusions: The online typing-tools reliably assign genotypes for enteroviruses and noroviruses. The use of phylogenetic methods makes these tools robust to ongoing evolution. This should facilitate standardized genotyping and nomenclature in clinical and public health laboratories, thus supporting inter-laboratory comparisons.
    MeSH term(s) Automation/methods ; Enterovirus/classification ; Enterovirus/genetics ; Genotype ; Humans ; Internet ; Molecular Typing/methods ; Norovirus/classification ; Norovirus/genetics ; Phylogeny ; Viral Proteins/genetics ; Virology/methods
    Chemical Substances Viral Proteins
    Language English
    Publishing date 2011-06
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1446080-4
    ISSN 1873-5967 ; 1386-6532
    ISSN (online) 1873-5967
    ISSN 1386-6532
    DOI 10.1016/j.jcv.2011.03.006
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    Zs.A 3790: Show issues Location:
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