Article: Chronic Kidney Disease and Its Clinical Correlates in a Rural Community in Southwestern Nigeria.
2023 Volume 33, Issue 6, Page(s) 774–783
Abstract: Chronic kidney disease (CKD) is a burgeoning problem globally, and more than a billion adults were affected as of 2016, with 1.2 million people dying from renal failure in 2017. To arrest the seemingly relentless progression of CKD to renal failure, ... ...
| Abstract | Chronic kidney disease (CKD) is a burgeoning problem globally, and more than a billion adults were affected as of 2016, with 1.2 million people dying from renal failure in 2017. To arrest the seemingly relentless progression of CKD to renal failure, there is a need to detect CKD early in the community. A community-based study was carried out to look at the prevalence and risk factors of CKD. Anthropometric and other clinical variables were measured. Blood samples were taken for determining creatinine, uric acid, urea, and lipids. CKD was defined as an estimated glomerular filtration rate of ≤60 mL/min/1.73 m2. Electrocardiograms and renal ultrasound scans were performed. In total, 201 people were recruited. Those with CKD had a male:female ratio of 1:3.9 and were older. The prevalence of autosomal-dominant polycystic kidney disease and CKD was 531.9 persons/100,000 population and 46.3%, respectively. Systolic blood pressure, pulse pressure, total cholesterol, triglycerides, high-density lipoprotein (HDL), uric acid, QTc interval, and electrocardiographic left ventricular hypertrophy were higher in those with CKD. Age, female sex, and HDL were independently associated with CKD. There was a steep rise in CKD at the community level. Increased awareness of CKD and prompt interventions are therefore imperative. |
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| MeSH term(s) | Adult ; Humans ; Male ; Female ; Nigeria/epidemiology ; Rural Population ; Uric Acid ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency/complications ; Risk Factors ; Glomerular Filtration Rate ; Prevalence |
| Chemical Substances | Uric Acid (268B43MJ25) |
| Language | English |
| Publishing date | 2023-11-29 |
| Publishing country | Saudi Arabia |
| Document type | Journal Article |
| ZDB-ID | 1379955-1 |
| ISSN | 1319-2442 |
| ISSN | 1319-2442 |
| DOI | 10.4103/1319-2442.390257 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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