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Article: Changes in Maternal Heart Rate Variability and Photoplethysmography Morphology after Corticosteroid Administration: A Prospective, Observational Study.

Bester, Maretha / Nichting, Thomas J / Joshi, Rohan / Aissati, Lamyae / Oei, Guid S / Mischi, Massimo / van Laar, Judith O E H / Vullings, Rik

Journal of clinical medicine

2024 Volume 13, Issue 8

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2024-04-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm13082442
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Article ; Online: Training and practical issues of breech and twin deliveries in the Netherlands.

Goossens, Simone M T A / Speck, Beau R G M / Bullens, Lauren M / Truijens, Sophie E M / Oei, Guid S G

European journal of obstetrics, gynecology, and reproductive biology

2018 Volume 224, Page(s) 205–207

MeSH term(s)	Breech Presentation ; Delivery, Obstetric/education ; Delivery, Obstetric/statistics & numerical data ; Female ; Humans ; Netherlands ; Pregnancy ; Pregnancy, Twin
Language	English
Publishing date	2018-03-20
Publishing country	Ireland
Document type	Letter
ZDB-ID	190605-7
ISSN	1872-7654 ; 0301-2115 ; 0028-2243
ISSN (online)	1872-7654
ISSN	0301-2115 ; 0028-2243
DOI	10.1016/j.ejogrb.2018.03.037
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Article ; Online: Learning curve of volume measurements by three-dimensional ultrasound with a rotational multi-planar technique (VOCAL), an in vitro study.

Smeets, Nicol A C / Winkens, Bjorn / Oei, Guid S

European journal of obstetrics, gynecology, and reproductive biology

2011 Volume 159, Issue 2, Page(s) 476–477

MeSH term(s)	Humans ; Imaging, Three-Dimensional/instrumentation ; Learning Curve ; Phantoms, Imaging ; Ultrasonography/instrumentation ; Ultrasonography/methods
Language	English
Publishing date	2011-12
Publishing country	Ireland
Document type	Letter
ZDB-ID	190605-7
ISSN	1872-7654 ; 0301-2115 ; 0028-2243
ISSN (online)	1872-7654
ISSN	0301-2115 ; 0028-2243
DOI	10.1016/j.ejogrb.2011.07.036
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Article ; Online: Intrapartum non-invasive electrophysiological monitoring: A prospective observational study.

Lempersz, Carlijn / Noben, Lore / van Osta, Gonnie / Wassen, Martine L H / Meershoek, Bert P J / Bakker, Petra / Jacquemyn, Yves / Cuerva, Marcos Javier / Vullings, Rik / Westerhuis, Michelle E M H / Oei, Guid S

Acta obstetricia et gynecologica Scandinavica

2020 Volume 99, Issue 10, Page(s) 1387–1395

Abstract: Introduction: Doppler ultrasound cardiotocography is a non-invasive alternative that, despite its poor specificity, is often first choice for intrapartum monitoring. Doppler ultrasound suffers from signal loss due to fetal movements and is negatively ... ...

Abstract	Introduction: Doppler ultrasound cardiotocography is a non-invasive alternative that, despite its poor specificity, is often first choice for intrapartum monitoring. Doppler ultrasound suffers from signal loss due to fetal movements and is negatively correlated with maternal body mass index (BMI). Reported accuracy of fetal heart rate monitoring by Doppler ultrasound varies between 10.6 and 14.3 bpm and reliability between 62.4% and 73%. The fetal scalp electrode (FSE) is considered the reference standard for fetal monitoring but can only be applied after membranes have ruptured with sufficient cervical dilatation and is sometimes contra-indicated. A non-invasive alternative that overcomes the shortcomings of Doppler ultrasound, providing reliable information on fetal heart rate, could be the answer. Non-invasive fetal electrocardiography (NI-fECG) uses a wireless electrode patch on the maternal abdomen to obtain both fetal and maternal heart rate signals as well as an electrohysterogram. We aimed to validate a wireless NI-fECG device for intrapartum monitoring in term singleton pregnancies, by comparison with the FSE. Material and methods: We performed a multicenter cross-sectional observational study at labor wards of 6 hospitals located in the Netherlands, Belgium, and Spain. Laboring women with a healthy singleton fetus in cephalic presentation and gestational age between 36 and 42 weeks were included. Participants received an abdominal electrode patch and FSE after written informed consent. Accuracy, reliability, and success rate of fetal heart rate readings were determined, using FSE as reference standard. Analysis was performed for the total population and measurement period as well as separated by labor stage and BMI class (≤30 and >30 kg/m Results: We included a total of 125 women. Simultaneous registrations with NI-fECG and FSE were available in 103 women. Overall accuracy is -1.46 bpm and overall reliability 86.84%. Overall success rate of the NI-fECG is around 90% for the total population as well as for both BMI subgroups. Success rate dropped to 63% during second stage of labor, similar results are found when looking at the separate BMI groups. Conclusions: Performance measures of the NI-fECG device are good in the overall group and the separate BMI groups. Compared with Doppler ultrasound performance measures from the literature, NI-fECG is a more accurate alternative. Especially, when women have a higher BMI, NI-fECG performs well, resembling FSE performance measures.
MeSH term(s)	Adult ; Body Mass Index ; Cardiotocography/instrumentation ; Cardiotocography/methods ; Cross-Sectional Studies ; Electrodes ; Female ; Heart Rate, Fetal ; Humans ; Pregnancy ; Prospective Studies ; Reproducibility of Results ; Wireless Technology
Language	English
Publishing date	2020-05-17
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't ; Validation Study
ZDB-ID	80019-3
ISSN	1600-0412 ; 0001-6349
ISSN (online)	1600-0412
ISSN	0001-6349
DOI	10.1111/aogs.13873
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Article ; Online: Study protocol: PoPE-Prediction of Preterm delivery by Electrohysterography.

de Lau, Hinke / Rabotti, Chiara / Oosterbaan, Herman P / Mischi, Massimo / Oei, Guid S

BMC pregnancy and childbirth

2014 Volume 14, Page(s) 192

Abstract: Background: Traditional methods used for prediction of preterm delivery are subjective and inaccurate. The Electrohysterogram (EHG) and in particular the estimation of the EHG conduction velocity, is a relatively new promising method for detecting ... ...

Abstract	Background: Traditional methods used for prediction of preterm delivery are subjective and inaccurate. The Electrohysterogram (EHG) and in particular the estimation of the EHG conduction velocity, is a relatively new promising method for detecting imminent preterm delivery. To date the analysis of the conduction velocity has relied on visual inspection of the signals. As a next step towards the introduction of EHG analysis as a clinical tool, we propose an automated method for EHG conduction velocity estimation for both the speed and direction of single spike propagation. Methods/design: The study design will be an observational cohort study. 100 pregnant women, gestational age between 23 + 5 and 34 weeks, admitted for threatening preterm labor or preterm prelabor rupture of membranes, will be included. The length of the cervical canal will be measured by transvaginal ultrasound. The EHG will be recorded using 4 electrodes in a fixed configuration. Contractions will be detected by analysis of the EHG and using an estimation of the intra uterine pressure. In the selected contractions, the delays between channels will be estimated by cross-correlation, and subsequently, the average EHG conduction velocity will be derived. Patients will be classified as labor group and non-labor group based on the time between measurement and delivery. The average conduction velocity and cervical length will be compared between the groups. The main study endpoints will be sensitivity, specificity, and area under the ROC curve for delivery within 1,2,4,7, and 14 days from the measurement. Discussion: In this study, the diagnostic accuracy of EHG conduction velocity analysis will be evaluated for detecting preterm labor. Visual and automatic detection of contractions will be compared. Planar wave propagation will be assumed for the calculation of the CV vector. Trial registration: Current Controlled Trials ISRCTN07603227.
MeSH term(s)	Area Under Curve ; Cohort Studies ; Electromyography/methods ; Female ; Gestational Age ; Humans ; Muscle Contraction/physiology ; Myometrium/physiopathology ; Predictive Value of Tests ; Pregnancy ; Premature Birth/diagnosis ; Premature Birth/physiopathology ; ROC Curve ; Research Design ; Signal Processing, Computer-Assisted ; Uterus/physiopathology
Language	English
Publishing date	2014-06-05
Publishing country	England
Document type	Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ISSN	1471-2393
ISSN (online)	1471-2393
DOI	10.1186/1471-2393-14-192
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Article ; Online: The impact of transmural multiprofessional simulation-based obstetric team training on perinatal outcome and quality of care in the Netherlands.

Banga, Franyke R / Truijens, Sophie E M / Fransen, Annemarie F / Dieleman, Jeanne P / van Runnard Heimel, Pieter J / Oei, Guid S

BMC medical education

2014 Volume 14, Page(s) 175

Abstract: Background: Perinatal mortality and morbidity in the Netherlands is relatively high compared to other European countries. Our country has a unique system with an independent primary care providing care to low-risk pregnancies and a secondary/tertiary ... ...

Abstract	Background: Perinatal mortality and morbidity in the Netherlands is relatively high compared to other European countries. Our country has a unique system with an independent primary care providing care to low-risk pregnancies and a secondary/tertiary care responsible for high-risk pregnancies. About 65% of pregnant women in the Netherlands will be referred from primary to secondary care implicating multiple medical handovers. Dutch audits concluded that in the entire obstetric collaborative network process parameters could be improved. Studies have shown that obstetric team training improves perinatal outcome and that simulation-based obstetric team training implementing crew resource management (CRM) improves team performance. In addition, deliberate practice (DP) improves medical skills. The aim of this study is to analyse whether transmural multiprofessional simulation-based obstetric team training improves perinatal outcome. Methods/design: The study will be implemented in the south-eastern part of the Netherlands with an annual delivery rate of over 9,000. In this area secondary care is provided by four hospitals. Each hospital with referring primary care practices will form a cluster (study group). Within each cluster, teams will be formed of different care providers representing the obstetric collaborative network. CRM and elements of DP will be implemented in the training. To analyse the quality of care as perceived by patients, the Pregnancy and Childbirth Questionnaire (PCQ) will be used. Furthermore, self-reported collaboration between care providers will be assessed. Team performance will be measured by the Clinical Teamwork Scale (CTS). We employ a stepped-wedge trial design with a sequential roll-out of the trainings for the different study groups.Primary outcome will be perinatal mortality and/or admission to a NICU. Secondary outcome will be team performance, quality of care as perceived by patients, and collaboration among care providers. Conclusion: The effect of transmural multiprofessional simulation-based obstetric team training on perinatal outcome has never been studied. We hypothesise that this training will improve perinatal outcome, team performance, and quality of care as perceived by patients and care providers. Trial registration: The Netherlands National Trial Register, http://www.trialregister.nl/NTR4576, registered June 1, 2014.
MeSH term(s)	Cause of Death ; Cooperative Behavior ; Female ; Humans ; Infant, Newborn ; Interdisciplinary Communication ; Netherlands ; Obstetrics/education ; Patient Care Team ; Perinatal Mortality ; Pregnancy ; Quality Improvement/organization & administration
Language	English
Publishing date	2014-08-21
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2044473-4
ISSN	1472-6920 ; 1472-6920
ISSN (online)	1472-6920
ISSN	1472-6920
DOI	10.1186/1472-6920-14-175
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Article: Inter-electrode delay estimators for electrohysterographic propagation analysis.

Rabotti, Chiara / Mischi, Massimo / van Laar, Judith O E H / Oei, Guid S / Bergmans, Jan W M

Physiological measurement

2009 Volume 30, Issue 8, Page(s) 745–761

Abstract: Premature birth is a major cause of mortality and permanent dysfunctions. Several parameters derived from single channel electrohysterographic (EHG) signals have been considered to determine contractions leading to preterm delivery. The results are ... ...

Abstract	Premature birth is a major cause of mortality and permanent dysfunctions. Several parameters derived from single channel electrohysterographic (EHG) signals have been considered to determine contractions leading to preterm delivery. The results are promising, but improvements are needed. As effective uterine contractions result from a proper action potential propagation, in this paper we focus on the propagation properties of EHG signals, which can be predictive of preterm delivery. Two standard delay estimators, namely maximization of the cross-correlation function and spectral matching, are adapted and implemented for the assessment of inter-electrode delays of propagating EHG signals. The accuracy of the considered standard estimators might be hampered by a poor inter-channel correlation. An improved dedicated approach is therefore proposed. By simultaneous adaptive estimation of the volume conductor transfer function and the delay, a dedicated method is conceived for improving the inter-channel signal similarity during delay calculation. Furthermore, it provides delay estimates without resolution limits and it is suitable for low sampling rates, which are appropriate for EHG recording. The three estimators were evaluated on EHG signals recorded on seven women. The dedicated approach provided more accurate estimates due to a 22% improvement of the initial average inter-channel correlation.
MeSH term(s)	Electrodes ; Electromyography/methods ; Feasibility Studies ; Female ; Humans ; Labor, Obstetric/physiology ; Models, Biological ; Myometrium/physiology ; Pregnancy ; Signal Processing, Computer-Assisted ; Time Factors
Language	English
Publishing date	2009-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1149545-5
ISSN	0967-3334
ISSN	0967-3334
DOI	10.1088/0967-3334/30/8/002
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Article: Estimation of internal uterine pressure by joint amplitude and frequency analysis of electrohysterographic signals.

Rabotti, Chiara / Mischi, Massimo / van Laar, Judith O E H / Oei, Guid S / Bergmans, Jan W M

Physiological measurement

2008 Volume 29, Issue 7, Page(s) 829–841

Abstract: Monitoring the uterine contraction provides important prognostic information during pregnancy and parturition. The existing methods employed in clinical practice impose a compromise between reliability and invasiveness. A promising technique for uterine ... ...

Abstract	Monitoring the uterine contraction provides important prognostic information during pregnancy and parturition. The existing methods employed in clinical practice impose a compromise between reliability and invasiveness. A promising technique for uterine contraction monitoring is electrohysterography (EHG). The EHG signal measures the electrical activity which triggers the contraction of the uterine muscle. In this paper, a non-invasive method for intrauterine pressure (IUP) estimation by EHG signal analysis is proposed. The EHG signal is regarded as a non-stationary signal whose frequency and amplitude characteristics are related to the IUP. After acquisition in a multi-channel configuration, the EHG signal is therefore analyzed in the time-frequency domain. A first estimation of the IUP is then derived by calculation of the unnormalized first statistical moment of the frequency spectrum. The estimation accuracy is finally increased by identification of a second-order polynomial model. The proposed method is compared to root mean squared analysis and optimal linear filtering and validated by simultaneous measurement of the IUP on nine women during labor. The results suggest that the proposed EHG signal analysis provides an accurate estimate of the IUP.
MeSH term(s)	Female ; Humans ; Pregnancy ; Pressure ; Signal Processing, Computer-Assisted ; Uterine Contraction/physiology ; Uterine Monitoring/methods ; Uterus/physiology
Language	English
Publishing date	2008-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1149545-5
ISSN	0967-3334
ISSN	0967-3334
DOI	10.1088/0967-3334/29/7/011
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Article ; Online: Maternal thyroid function and the outcome of external cephalic version: a prospective cohort study.

Kuppens, Simone M / Kooistra, Libbe / Hasaart, Tom H / van der Donk, Riet W / Vader, Huib L / Oei, Guid S / Pop, Victor J

BMC pregnancy and childbirth

2011 Volume 11, Page(s) 10

Abstract: Background: To investigate the relation between maternal thyroid function and the outcome of external cephalic version (ECV) in breech presentation.: Methods: Prospective cohort study in 141 women (≥ 35 weeks gestation) with a singleton fetus in ... ...

Abstract	Background: To investigate the relation between maternal thyroid function and the outcome of external cephalic version (ECV) in breech presentation. Methods: Prospective cohort study in 141 women (≥ 35 weeks gestation) with a singleton fetus in breech. Blood samples for assessing thyroid function were taken prior to ECV. Main outcome measure was the relation between maternal thyroid function and ECV outcome indicated by post ECV ultrasound. Results: ECV success rate was 77/141 (55%), 41/48 (85%) in multipara and 36/93 (39%) in primipara. Women with a failed ECV attempt had significantly higher TSH concentrations than women with a successful ECV (p < 0.001). Multiple logistic regression showed that TSH (OR: 0.52, 95% CI: 0.30-0.90), nulliparity (OR: 0.11, 95% CI: 0.03-0.36), frank breech (OR: 0.30, 95% CI: 0.10-0.93) and placenta anterior (OR: 0.31, 95% CI: 0.11-0.85) were independently related to ECV success. Conclusions: Higher TSH levels increase the risk of ECV failure. Trial registration number: ClinicalTrials.gov: NCT00516555.
MeSH term(s)	Adult ; Breech Presentation/therapy ; Female ; Humans ; Logistic Models ; Middle Aged ; Pregnancy/physiology ; Prospective Studies ; Statistics, Nonparametric ; Thyroid Gland/physiology ; Thyrotropin/blood ; Thyroxine/blood ; Treatment Outcome ; Ultrasonography, Prenatal ; Version, Fetal ; Young Adult
Chemical Substances	Thyrotropin (9002-71-5) ; Thyroxine (Q51BO43MG4)
Language	English
Publishing date	2011-01-26
Publishing country	England
Document type	Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1471-2393
ISSN (online)	1471-2393
DOI	10.1186/1471-2393-11-10
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Article ; Online: Maternal thyroid function and the outcome of external cephalic version

van der Donk Riet W / Hasaart Tom H / Kooistra Libbe / Kuppens Simone M / Vader Huib L / Oei Guid S / Pop Victor J

BMC Pregnancy and Childbirth, Vol 11, Iss 1, p

a prospective cohort study

2011 Volume 10

Abstract: Abstract Background To investigate the relation between maternal thyroid function and the outcome of external cephalic version (ECV) in breech presentation. Methods Prospective cohort study in 141 women (≥ 35 weeks gestation) with a singleton fetus in ... ...

Abstract	Abstract Background To investigate the relation between maternal thyroid function and the outcome of external cephalic version (ECV) in breech presentation. Methods Prospective cohort study in 141 women (≥ 35 weeks gestation) with a singleton fetus in breech. Blood samples for assessing thyroid function were taken prior to ECV. Main outcome measure was the relation between maternal thyroid function and ECV outcome indicated by post ECV ultrasound. Results ECV success rate was 77/141 (55%), 41/48 (85%) in multipara and 36/93 (39%) in primipara. Women with a failed ECV attempt had significantly higher TSH concentrations than women with a successful ECV (p < 0.001). Multiple logistic regression showed that TSH (OR: 0.52, 95% CI: 0.30-0.90), nulliparity (OR: 0.11, 95% CI: 0.03-0.36), frank breech (OR: 0.30, 95% CI: 0.10-0.93) and placenta anterior (OR: 0.31, 95% CI: 0.11-0.85) were independently related to ECV success. Conclusions Higher TSH levels increase the risk of ECV failure. Trial registration number ClinicalTrials.gov: NCT00516555
Keywords	Gynecology and obstetrics ; RG1-991 ; Medicine ; R ; DOAJ:Gynecology and Obstetrics ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	610
Language	English
Publishing date	2011-01-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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