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  1. Article ; Online: Adjuvant Chemotherapy With UFT/LV

    Ogawa, Hiroomi / Shiraishi, Takuya / Okada, Takuhisa / Miyamae, Yohei / Motegi, Yoko / Shirabe, Ken / Saeki, Hiroshi

    Anticancer research

    2024  Volume 44, Issue 2, Page(s) 805–814

    Abstract: Background/aim: Uracil-tegafur+leucovorin (UFT/LV), an oral adjuvant therapy for stage II/III colorectal cancer, is non-inferior to standard weekly fluorouracil and folinate. Although polysaccharide K (PSK) has been evaluated as a postoperative adjuvant ...

    Abstract Background/aim: Uracil-tegafur+leucovorin (UFT/LV), an oral adjuvant therapy for stage II/III colorectal cancer, is non-inferior to standard weekly fluorouracil and folinate. Although polysaccharide K (PSK) has been evaluated as a postoperative adjuvant colorectal cancer drug, its efficacy remains unclear. This randomized phase II trial compared UFT/LV+PSK with UFT/LV as adjuvant chemotherapy.
    Patients and methods: Between April 2011 and August 2016, 186 patients who underwent radical resection randomly received 6 months of UFT/LV (Group A: 300 mg/m
    Results: Groups A, B, and C consisted of 37, 75, and 74 patients, of which treatment was completed by 33 (89.2%), 63 (84.9%), and 53 (70.4%) patients, respectively (p=0.0279). Adverse event incidence for all grades were 59.5%, 52.1%, and 59.2%, and for grade ≥3 were 13.5%, 9.6%, and 9.9%, respectively. The 3-year disease-free survival rates were 72.5%, 82.2%, and 74.2%, respectively, with no significant differences. The preoperative lymphocyte ratio did not significantly differ between groups.
    Conclusion: UFT/LV+PSK is comparable to UFT/LV therapy in terms of prognostic efficacy and reduced adverse effects. Thus, UFT/LV+PSK is a useful adjuvant chemotherapy option for patients with high-risk stage II/III colorectal cancer.
    MeSH term(s) Humans ; Administration, Oral ; Chemotherapy, Adjuvant/adverse effects ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/pathology ; Leucovorin/therapeutic use ; Levamisole/analogs & derivatives ; Neoplasm Staging ; Tegafur/therapeutic use ; Uracil/therapeutic use
    Chemical Substances Leucovorin (Q573I9DVLP) ; Levamisole (2880D3468G) ; Tegafur (1548R74NSZ) ; Uracil (56HH86ZVCT)
    Language English
    Publishing date 2024-02-01
    Publishing country Greece
    Document type Clinical Trial, Phase II ; Randomized Controlled Trial ; Journal Article
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    DOI 10.21873/anticanres.16872
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Damage to the Descending Colon after Endoscopic Balloon Dilatation following a Minor Traffic Accident in a Patient with Crohn's Disease: A Case Report.

    Seki, Takaomi / Osone, Katsuya / Ogawa, Hiroomi / Okada, Takuhisa / Shiraishi, Takuya / Sohda, Makoto / Shirabe, Ken / Saeki, Hiroshi

    Case reports in gastroenterology

    2024  Volume 18, Issue 1, Page(s) 244–251

    Abstract: Introduction: Crohn's disease (CD) is complicated by intestinal strictures and fistula formation; however, intestinal perforation is relatively rare.: Case presentation: Following a traffic accident in the evening, a 39-year-old woman experienced ... ...

    Abstract Introduction: Crohn's disease (CD) is complicated by intestinal strictures and fistula formation; however, intestinal perforation is relatively rare.
    Case presentation: Following a traffic accident in the evening, a 39-year-old woman experienced abdominal pain that worsened the following morning and was taken to the emergency department. She had a 17-year history of CD and eight endoscopic balloon dilations for descending colonic strictures. She presented with a high fever of 40.0°C, along with tenderness and rebound pain throughout her abdomen, with the most substantial point being in the lower left abdomen. Computed tomography showed thickening of the descending colon wall, increased fat concentration around the wall, and a slight presence of air in the mesentery near the intestinal wall. We diagnosed the patient with generalized peritonitis due to traumatic penetration of the mesentery of the descending colon and performed emergency surgery. Intraoperative observation of the abdominal cavity with a laparoscope revealed purulent ascites but no apparent perforation or edematous mesentery, with white moss and redness in the descending colon. This prompted the decision to perform peritoneal lavage drainage and a transverse colonic double colostomy. The postoperative course was favorable, and the patient was discharged from the hospital on the postoperative day 14. Four months after discharge, colostomy closure was performed.
    Conclusion: Relatively minor trauma in patients with CD can result in colon injury. An injured bowel is usually accompanied by active lesions due to CD; however, caution is required, as endoscopic balloon dilatation without accompaniment may be a background factor.
    Language English
    Publishing date 2024-04-25
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000537973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Preoperative factors associated with lateral lymph node metastasis in lower rectal cancer and the evaluation of the middle rectal artery.

    Shiraishi, Takuya / Ogawa, Hiroomi / Yamaguchi, Arisa / Shibasaki, Yuta / Osone, Katsuya / Okada, Takuhisa / Sakai, Makoto / Sohda, Makoto / Shirabe, Ken / Saeki, Hiroshi

    Surgery today

    2024  

    Abstract: Purpose: This study aimed to identify cases in which lateral lymph node (LLN) dissection (LLND) can be excluded by clarifying preoperative factors, including an evaluation of the middle rectal artery (MRA), associated with LLN metastasis.: Methods: ... ...

    Abstract Purpose: This study aimed to identify cases in which lateral lymph node (LLN) dissection (LLND) can be excluded by clarifying preoperative factors, including an evaluation of the middle rectal artery (MRA), associated with LLN metastasis.
    Methods: Fifty-five consecutive patients who underwent preoperative positron emission tomography-computed tomography (PET/CT) and total mesorectal excision with LLND for rectal cancer were included. We retrospectively investigated the preoperative clinical factors associated with pathological LLN (pLLN) metastasis. We analyzed the regions of pLLN metastasis using MRA.
    Results: pLLN metastasis occurred in 13 (23.6%) patients. According to a multivariate analysis, clinical LLN (cLLN) metastasis based on short-axis size and LLN status based on PET/CT were independent preoperative factors of pLLN metastasis. The negative predictive value (NPV) was high (97.1%) in patients evaluated as negative based on PET/CT and cLLN short-axis size. MRA was detected in 24 patients (43.6%) using contrast-enhanced CT, and there was a significant relationship between pLLN metastasis and the presence of MRA. pLLN metastasis in the internal iliac region but not in the obturator region was significantly correlated with the presence of MRA.
    Conclusion: Combined cLLN metastasis based on short-axis size and PET/CT showed a higher NPV, suggesting this to be a useful method for identifying cases in which LLND can be excluded.
    Language English
    Publishing date 2024-05-20
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1115435-4
    ISSN 1436-2813 ; 0941-1291
    ISSN (online) 1436-2813
    ISSN 0941-1291
    DOI 10.1007/s00595-024-02868-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Role of surgical resection and its alternative local therapy for pulmonary metastasis of colorectal cancer.

    Ogawa, Hiroomi / Yajima, Toshiki / Sohda, Makoto / Shirabe, Ken / Saeki, Hiroshi

    Annals of gastroenterological surgery

    2021  Volume 5, Issue 6, Page(s) 747–753

    Abstract: We reviewed surgical and alternative treatments for pulmonary metastasis of colorectal cancer, focusing on recent reports. The standard treatment for pulmonary metastasis of colorectal cancer is pulmonary resection, if resectable, despite the fact that ... ...

    Abstract We reviewed surgical and alternative treatments for pulmonary metastasis of colorectal cancer, focusing on recent reports. The standard treatment for pulmonary metastasis of colorectal cancer is pulmonary resection, if resectable, despite the fact that the metastasis is hematogenous to distant organs. Guidelines in several countries, including Japan, have described pulmonary resection as a useful option because of the favorable long-term prognosis reported in various studies pertaining to pulmonary resection. The indications for pulmonary resection have been reviewed in several studies; additionally, the number of metastases, pretreatment carcinoembryonic antigen value, and disease-free interval from the primary resection to pulmonary recurrence have been proposed. However, no consensus has been reached to date. Contrastingly, recent advances in chemotherapy have remarkably improved the outcome of distant metastases, indicating that it is time to reconsider the significance of local treatment, including pulmonary resection. In addition to surgical resection, minimally invasive therapies, such as stereotactic body radiation therapy and radiofrequency ablation have been developed as local treatments for pulmonary metastases, and their long-term results have been reported. Prospective controlled trials and large-scale data analyses are needed to determine the best local treatment for pulmonary metastases and to find the appropriate indication for each treatment.
    Language English
    Publishing date 2021-05-24
    Publishing country Japan
    Document type Journal Article ; Review
    ISSN 2475-0328
    ISSN (online) 2475-0328
    DOI 10.1002/ags3.12472
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effectiveness of Combination Chemotherapy With Docetaxel, Nedaplatin, and 5-Fluorouracil for Advanced and Recurrent Esophageal Cancer.

    Sohda, Makoto / Hara, Keigo / Kuriyama, Kengo / Tateno, Kouhei / Uchida, Shintaro / Watanabe, Takayoshi / Shibasaki, Yuta / Saito, Hideyuki / Nakazawa, Nobuhiro / Sano, Akihiko / Sakai, Makoto / Yokobori, Takehiko / Ogawa, Hiroomi / Shirabe, Ken / Saeki, Hiroshi

    Anticancer research

    2024  Volume 44, Issue 3, Page(s) 1309–1315

    Abstract: Background/aim: Chemotherapy and immunotherapy have been recently developed as potentially useful first-line treatments for unresectable, advanced, or recurrent esophageal cancer. We performed a retrospective study of the therapeutic effectiveness of ... ...

    Abstract Background/aim: Chemotherapy and immunotherapy have been recently developed as potentially useful first-line treatments for unresectable, advanced, or recurrent esophageal cancer. We performed a retrospective study of the therapeutic effectiveness of triplet chemotherapy with docetaxel, nedaplatin, and 5-fluorouracil therapy for advanced, recurrent, and unresectable advanced esophageal cancer at our hospital and compared the regimen's results with those of current and possible future treatment options.
    Patients and methods: The study cohort comprised 101 patients who received docetaxel, nedaplatin, and 5-fluorouracil for advanced or recurrent esophageal cancer at Gunma University from May 2008 to December 2017. We retrospectively evaluated the results of this combination chemotherapy and postulated future treatment strategies.
    Results: The overall response and disease control rates, the latter including stable disease, for docetaxel, nedaplatin, and 5-fluorouracil were 33.6% and 61.4%, respectively. The median overall survival and progression-free survival were 12.26 months and 5.1 months, respectively. In patients with recurrence, the median overall and progression-free survivals were 14.97 months (449 days) and 5.1 months (152 days), respectively. No study patients developed acute kidney injury and there were no treatment-related deaths. However, leukopenia and neutropenia were frequent hematologic toxicities.
    Conclusion: Treatment with docetaxel, nedaplatin, and 5-fluorouracil for advanced or recurrent esophageal cancer is particularly useful for recurrent cases and has the advantage of not causing severe renal dysfunction.
    MeSH term(s) Humans ; Docetaxel ; Retrospective Studies ; Fluorouracil ; Drug Therapy, Combination ; Neutropenia ; Esophageal Neoplasms/drug therapy ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Cisplatin ; Organoplatinum Compounds
    Chemical Substances Docetaxel (15H5577CQD) ; nedaplatin (8UQ3W6JXAN) ; Fluorouracil (U3P01618RT) ; Cisplatin (Q20Q21Q62J) ; Organoplatinum Compounds
    Language English
    Publishing date 2024-02-29
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    DOI 10.21873/anticanres.16926
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A Novel Method for Thoracoscopic Overlap Esophagogastric Reconstruction With Pleural Closure following Minimally Invasive Ivor-Lewis Esophagectomy for Esophagogastric Junction Cancer.

    Sano, Akihiko / Sohda, Makoto / Hosoi, Nobuhiro / Tateno, Kohei / Watanabe, Takayoshi / Nakazawa, Nobuhiro / Shioi, Ikuma / Shibasaki, Yuta / Okada, Takuhisa / Osone, Katsuya / Shiraishi, Takuya / Sakai, Makoto / Ogawa, Hiroomi / Okabe, Hiroshi / Shirabe, Ken / Saeki, Hiroshi

    Surgical laparoscopy, endoscopy & percutaneous techniques

    2024  Volume 34, Issue 1, Page(s) 108–112

    Abstract: Background: Intrathoracic esophagogastric anastomosis following minimally invasive Ivor-Lewis esophagectomy is a technically demanding surgical technique that can result in serious intrathoracic infections when anastomotic leakage occurs. Herein, we ... ...

    Abstract Background: Intrathoracic esophagogastric anastomosis following minimally invasive Ivor-Lewis esophagectomy is a technically demanding surgical technique that can result in serious intrathoracic infections when anastomotic leakage occurs. Herein, we report a novel side-overlap esophagogastric anastomosis with pleural closure for esophagogastric junction cancer.
    Methods: The 3 key points of our novel technique were the following: (1) overlap esophagogastric anastomosis and closure of the entry hole were all performed using a linear stapler; (2) the pleura was closed to separate the anastomotic site from the thoracic cavity; and (3) the mediastinal drain was inserted transhiatally from the abdominal cavity.
    Results: This modified anastomosis procedure was performed on 8 consecutive patients at our institution. The median overall/thoracoscopic operating time and estimated blood loss were 652.5/241.5 min and 89 mL, respectively. No mortality or serious postoperative complications occurred, and the median postoperative hospital stay was 22 days (range, 17 to 37 d).
    Conclusion: This novel thoracoscopic overlap esophagogastric reconstruction procedure with pleural closure is safe and feasible.
    MeSH term(s) Humans ; Esophagectomy/methods ; Pleura/surgery ; Esophageal Neoplasms/surgery ; Esophagogastric Junction/surgery ; Anastomotic Leak/surgery ; Anastomosis, Surgical/methods ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Retrospective Studies
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1475108-2
    ISSN 1534-4908 ; 1530-4515 ; 1051-7200
    ISSN (online) 1534-4908
    ISSN 1530-4515 ; 1051-7200
    DOI 10.1097/SLE.0000000000001250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Two-Team Transanal Total Mesorectal Excision and En Bloc Resection of the Lateral Pelvic Lymph Nodes, Main Iliac Vessels, and Pelvic Plexus for Locally Advanced Rectal Cancer With Lateral Lymph Node Metastasis.

    Shioi, Ikuma / Ogawa, Hiroomi / Hosoi, Nobuhiro / Yamaguchi, Arisa / Watanabe, Takayoshi / Nakazawa, Nobuhiro / Shibasaki, Yuta / Shiraishi, Takuya / Osone, Katsuya / Okada, Takuhisa / Sano, Akihiko / Sakai, Makoto / Sohda, Makoto / Shirabe, Ken / Saeki, Hiroshi

    Surgical laparoscopy, endoscopy & percutaneous techniques

    2024  Volume 34, Issue 2, Page(s) 237–241

    Abstract: Background: Here, we describe the precise surgical technique for a novel procedure involving 2-team transanal total mesorectal excision with en bloc lateral pelvic lymph node (LPLN) dissection combined with resection of the involved main internal iliac ... ...

    Abstract Background: Here, we describe the precise surgical technique for a novel procedure involving 2-team transanal total mesorectal excision with en bloc lateral pelvic lymph node (LPLN) dissection combined with resection of the involved main internal iliac vessels and pelvic plexus.
    Methods: From September 2020 to May 2023, 4 patients underwent the procedure at our hospital.
    Results: The operation time and blood loss were 272 to 412 minutes and 10 to 124 mL, respectively. No patients required conversion to open surgery or exhibited Clavien-Dindo grade III or worse postoperative complications, although 2 developed grade II urinary dysfunction. All surgical margins were negative.
    Conclusions: Our novel 2-team method can facilitate safe and satisfactory surgery, even for highly advanced rectal cancer. The transanal approach offers excellent visibility and operability, even during LPLN and adjacent structure dissection. Furthermore, initial dissection of the distal branches of the iliac vessels prevents excessive lymphatic tissue congestion, facilitating easier, and clearer dissection.
    MeSH term(s) Humans ; Lymphatic Metastasis/pathology ; Hypogastric Plexus/pathology ; Lymph Nodes/surgery ; Lymph Nodes/pathology ; Lymph Node Excision/methods ; Rectal Neoplasms/surgery ; Rectal Neoplasms/pathology ; Retrospective Studies
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1475108-2
    ISSN 1534-4908 ; 1530-4515 ; 1051-7200
    ISSN (online) 1534-4908
    ISSN 1530-4515 ; 1051-7200
    DOI 10.1097/SLE.0000000000001268
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Squamous cell carcinoma of the anus successfully treated with multidisciplinary therapy for metachronous metastatic and local recurrences after DCF chemotherapy: a case report.

    Naito, Ryozan / Shiraishi, Takuya / Hosoi, Nobuhiro / Watanabe, Takayoshi / Shioi, Ikuma / Shibasaki, Yuta / Nakazawa, Nobuhiro / Osone, Katsuya / Okada, Takuhisa / Sano, Akihiko / Sakai, Makoto / Ogawa, Hiroomi / Sohda, Makoto / Shirabe, Ken / Saeki, Hiroshi

    Surgical case reports

    2024  Volume 10, Issue 1, Page(s) 71

    Abstract: Background: Docetaxel, cisplatin, and 5-fluorouracil (DCF) chemotherapy is reportedly an effective treatment strategy for squamous cell carcinoma of the anus (SCCA). However, studies regarding its use in Japanese patients remain scarce.: Case ... ...

    Abstract Background: Docetaxel, cisplatin, and 5-fluorouracil (DCF) chemotherapy is reportedly an effective treatment strategy for squamous cell carcinoma of the anus (SCCA). However, studies regarding its use in Japanese patients remain scarce.
    Case presentation: Here, we present the case of an 82-year-old woman with SCCA, cStage IIIB. Chemoradiotherapy was initiated after colostomy of the anorectal mass; however, para-aortic lymph node recurrence was observed 3 months after treatment completion. Five courses of DCF chemotherapy were subsequently administered, resulting in a complete response (CR). Two years and 1 month later, the aortic lymph node was enlarged again, and the patient achieved CR again after radiotherapy. Nine months later, local recurrence was detected in the anal canal, and laparoscopic perineal rectal amputation was performed. The patient remains progression-free 5 years and 10 months after the initial treatment and 1 year and 7 months after the final treatment.
    Conclusions: Our findings suggest that complementary treatment after DCF chemotherapy may be efficacious in Japanese patients with SCCA and help achieve CR. Despite occasional local recurrences, this approach may help achieve long-term progression-free survival.
    Language English
    Publishing date 2024-03-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2809613-7
    ISSN 2198-7793
    ISSN 2198-7793
    DOI 10.1186/s40792-024-01873-2
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  9. Article ; Online: Efficacy of thoracic endovascular aortic repair for aorto-esophageal fistula due to esophageal cancer: a systematic review and meta-analysis.

    Sakai, Makoto / Sohda, Makoto / Uchida, Shintaro / Yamaguchi, Arisa / Watanabe, Takayoshi / Saito, Hideyuki / Nakazawa, Nobuhiro / Kuriyama, Kengo / Sano, Akihiko / Ogawa, Hiroomi / Yokobori, Takehiko / Nagai, Kazue / Shirabe, Ken / Saeki, Hiroshi

    Esophagus : official journal of the Japan Esophageal Society

    2024  Volume 21, Issue 2, Page(s) 95–101

    Abstract: Aorto-esophageal fistula (AEF) due to esophageal cancer (EC) is a life-threatening condition characterized by sudden hemorrhage, which often causes sudden death. To evaluate the efficacy and safety of thoracic endovascular aortic repair (TEVAR) for AEF ... ...

    Abstract Aorto-esophageal fistula (AEF) due to esophageal cancer (EC) is a life-threatening condition characterized by sudden hemorrhage, which often causes sudden death. To evaluate the efficacy and safety of thoracic endovascular aortic repair (TEVAR) for AEF due to EC, we performed a systematic review and meta-analysis. We searched the MEDLINE (PubMed) databases, the Cochrane Library databases, Ichushi-Web (the databases of the Japan Medical Abstract Society), and CiNii (Academic information search service of the National Institute of Information from Japan) from January 2000 to November 2023 for articles about TEVAR for an emergent aortic hemorrhage (salvage TEVAR [S-TEVAR]), and the prophylactic procedure (P-TEVAR). Six studies (140 cases) were eligible for meta-analysis. The 90-day mortality of S-TEVAR and P-TEVAR was 40% (95% CI 23-60, I
    MeSH term(s) Humans ; Endovascular Aneurysm Repair ; Aorta, Thoracic/surgery ; Blood Vessel Prosthesis Implantation/adverse effects ; Treatment Outcome ; Aortic Diseases/etiology ; Aortic Diseases/surgery ; Hemorrhage/etiology ; Esophageal Fistula/etiology ; Esophageal Fistula/surgery ; Esophageal Neoplasms/complications ; Esophageal Neoplasms/surgery
    Language English
    Publishing date 2024-02-01
    Publishing country Japan
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2133367-1
    ISSN 1612-9067 ; 1612-9059
    ISSN (online) 1612-9067
    ISSN 1612-9059
    DOI 10.1007/s10388-024-01042-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Idiopathic pneumoperitoneum diagnosed following high-energy motor vehicular trauma:a case report.

    Ubukata, Yasunari / Sohda, Makoto / Sakai, Makoto / Nakazawa, Nobuhiro / Hara, Keigo / Sano, Akihiko / Ogawa, Hiroomi / Shirabe, Ken / Saeki, Hiroshi

    The journal of medical investigation : JMI

    2022  Volume 69, Issue 1.2, Page(s) 155–157

    Abstract: Intra-abdominal free gas is a finding of extra-intestinal gas in the abdominal cavity on radiography or CT, mainly suggesting gastrointestinal perforation and necessitating emergency surgery. Idiopathic pneumoperitoneum is diagnosed when there is no ... ...

    Abstract Intra-abdominal free gas is a finding of extra-intestinal gas in the abdominal cavity on radiography or CT, mainly suggesting gastrointestinal perforation and necessitating emergency surgery. Idiopathic pneumoperitoneum is diagnosed when there is no obvious gastrointestinal perforation, but there is presence of free gas in the abdominal cavity with an unidentifiable cause. Herein, we report a case of idiopathic pneumoperitoneum secondary to high-energy trauma following a car rollover accident. A 95-year-old man was transferred to our clinic after a car-to-car rollover accident. He had abrasions on his right upper arm and left abdomen that appeared to be the result of the accident;however, no other apparent traumatic injuries were noted. There was no pain in the abdomen, and peritoneal irritation symptoms were also not noted. A CT scan showed fine free air. Although idiopathic pneumoperitoneum could not be ruled out, considering the patient's background and the possibility of traumatic small bowel perforation, emergency surgery was performed. A thorough search of the abdominal cavity was performed;however, the surgery was completed without an obvious perforation site. Idiopathic pneumoperitoneum should be considered as a differential disease in cases who have free air on abdominal CT but clinically lack obvious inflammatory reaction findings. J. Med. Invest. 69 : 155-157, February, 2022.
    MeSH term(s) Abdomen ; Aged, 80 and over ; Humans ; Injections, Intraperitoneal ; Male ; Pneumoperitoneum/diagnostic imaging ; Pneumoperitoneum/etiology ; Pneumoperitoneum/surgery ; Radiography ; Tomography, X-Ray Computed
    Language English
    Publishing date 2022-04-24
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 1435233-3
    ISSN 1349-6867 ; 1343-1420
    ISSN (online) 1349-6867
    ISSN 1343-1420
    DOI 10.2152/jmi.69.155
    Database MEDical Literature Analysis and Retrieval System OnLINE

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