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  1. Article ; Online: Visceral fat accumulation and metabolic syndrome in children: the impact of Trp64Arg polymorphism of the beta3-adrenergic receptor gene.

    Oguri, Kazuo / Tachi, Toshiki / Matsuoka, Toshio

    Acta paediatrica (Oslo, Norway : 1992)

    2013  Volume 102, Issue 6, Page(s) 613–619

    Abstract: Aim: To investigate the association between Trp64Arg polymorphism of the beta3-adrenergic receptor (ADRB3) gene and total fat mass, abdominal fat distribution, other metabolic derangements and metabolic syndrome (MS) in Japanese children.: Methods: ... ...

    Abstract Aim: To investigate the association between Trp64Arg polymorphism of the beta3-adrenergic receptor (ADRB3) gene and total fat mass, abdominal fat distribution, other metabolic derangements and metabolic syndrome (MS) in Japanese children.
    Methods: Molecular screening of the ADRB3 gene polymorphism (Trp64Trp, Trp64Arg and Arg64Arg) was carried out in 132 children aged 6-12 years: 73 were obese (45 boys) and 59 were not obese (27 boys). Visceral fat (VF) and subcutaneous fat (SF) area were measured using magnetic resonance imaging, blood pressure, lipid and glucose profiles.
    Results: The frequencies of Arg carriers (Trp64Arg or Arg64Arg) were significantly higher in obese children with MS, compared to obese children without MS and nonobese children. In obese children, Arg carriers had significantly higher VF area, systolic and diastolic blood pressure, and low-density lipoprotein cholesterol and triglyceride than Arg noncarriers (Trp64Trp). However, there were no differences in total fat mass and SF area between the two groups. In nonobese children, none of these parameters differed significantly between Arg carriers and noncarriers.
    Conclusion: Trp64Arg polymorphism of the ADRB3 gene may affect VF accumulation and be associated with MS, a cluster of conditions involving aggravated lipid metabolism and higher blood pressure, in Japanese children.
    MeSH term(s) Blood Pressure ; Body Mass Index ; Child ; Comorbidity ; Female ; Humans ; Intra-Abdominal Fat/metabolism ; Leptin/blood ; Magnetic Resonance Imaging ; Male ; Metabolic Syndrome/diagnosis ; Metabolic Syndrome/epidemiology ; Metabolic Syndrome/genetics ; Metabolic Syndrome/metabolism ; Obesity, Abdominal/epidemiology ; Polymorphism, Genetic ; Receptors, Adrenergic, beta-3/genetics
    Chemical Substances ADRB3 protein, human ; Leptin ; Receptors, Adrenergic, beta-3
    Language English
    Publishing date 2013-06
    Publishing country Norway
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.12149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Whole-body vibration training improves the walking ability of a moderately impaired child with cerebral palsy: a case study.

    Yabumoto, Tamotsu / Shin, Sohee / Watanabe, Tsuneo / Watanabe, Yusuke / Naka, Toru / Oguri, Kazuo / Matsuoka, Toshio

    Journal of physical therapy science

    2015  Volume 27, Issue 9, Page(s) 3023–3025

    Abstract: Purpose] Strength training is recommended for children with cerebral palsy. However, it is difficult for moderately impaired children with cerebral palsy, who require crutches for ambulation, to participate in this type of training. The purpose of this ... ...

    Abstract [Purpose] Strength training is recommended for children with cerebral palsy. However, it is difficult for moderately impaired children with cerebral palsy, who require crutches for ambulation, to participate in this type of training. The purpose of this study was to investigate whether whole-body vibration training is an effective method of strengthening in a moderately impaired child with cerebral palsy. [Subject and Methods] This report describes an 8-year-old Japanese boy with cerebral palsy, who was ambulatory with crutches. The subject participated in physical therapy twice a week for 5 weeks. Whole-body vibration training was selected to complement the standing practice. The patient's crutch-walking ability, gross motor function, and spasticity were evaluated. [Results] The number of steps and walking duration were reduced in a 5-m walk test with crutches and gross motor function was improved. Further, the spasticity was reduced. [Conclusion] Whole-body vibration training is an effective physical therapy intervention in moderately impaired children with cerebral palsy, who are unable to walk without crutches.
    Language English
    Publishing date 2015-09-30
    Publishing country Japan
    Document type Case Reports
    ZDB-ID 2038898-6
    ISSN 0915-5287
    ISSN 0915-5287
    DOI 10.1589/jpts.27.3023
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  3. Article: Relationship between the thickness and hemodynamics of the erector spinae muscles in various lumbar curvatures.

    Masuda, Takahiro / Miyamoto, Kei / Oguri, Kazuo / Matsuoka, Toshio / Shimizu, Katsuji

    Clinical biomechanics (Bristol, Avon)

    2005  Volume 20, Issue 3, Page(s) 247–253

    Abstract: Background: There is little information about the relationship between the changes of hemodynamics and the morphologic changes of the erector spinae muscle.: Methods: Fifty healthy male volunteers participated. Ultrasonography was used to measure ... ...

    Abstract Background: There is little information about the relationship between the changes of hemodynamics and the morphologic changes of the erector spinae muscle.
    Methods: Fifty healthy male volunteers participated. Ultrasonography was used to measure muscle thickness, and near-infrared spectroscopy was used to measure tissue blood volume and its oxygenation in the erector spinae muscle at L3 in six different relaxed trunk postures (flexed 20 degrees , flexed 40 degrees, flexed maximum, neutral posture, extended 20 degrees, and extended maximum of the lumbar spine). We also evaluated the reproducibility of the near-infrared spectroscopy measurements.
    Findings: Near-infrared spectroscopy gave highly reproducible measurements. The thickness of the erector spinae muscle and the total and oxygenated hemoglobin were simultaneously increased during relaxed extension and decreased during relaxed flexion. Changes in the thickness of the erector spinae muscle with various lumbar curvature were similar in pattern to the changes in tissue blood volume and its oxygenation.
    Interpretation: The erector spinae muscles' thickness, tissue blood volume, and its oxygenation are simultaneously increased during relaxed extension and decreased during relaxed flexion, as demonstrated by non-invasive near-infrared spectroscopy and ultrasonography. These findings might afford a better understanding of the pathomechanics of posture-related back symptoms.
    Relevance: The erector spinae muscles' thickness, tissue blood volume, and its oxygenation are simultaneously increased during relaxed extension and decreased during relaxed flexion, as shown by non-invasive near-infrared spectroscopy and ultrasonography. Changes in hemodynamics and morphology of the erector spinae muscles in asymptomatic subjects are given for further research on the pathomechanism of back pain.
    MeSH term(s) Adult ; Blood Volume/physiology ; Humans ; Lumbar Vertebrae/blood supply ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/physiology ; Male ; Middle Aged ; Muscle, Skeletal/blood supply ; Muscle, Skeletal/diagnostic imaging ; Muscle, Skeletal/physiology ; Oxygen/metabolism ; Oxygen Consumption/physiology ; Posture/physiology ; Statistics as Topic ; Ultrasonography
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2005-03
    Publishing country England
    Document type Clinical Trial ; Comparative Study ; Journal Article
    ZDB-ID 632747-3
    ISSN 1879-1271 ; 0268-0033
    ISSN (online) 1879-1271
    ISSN 0268-0033
    DOI 10.1016/j.clinbiomech.2004.10.008
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2876: Show issues Location:
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  4. Article: Heart rate recovery after exercise and neural regulation of heart rate variability in 30-40 year old female marathon runners.

    Du, Na / Bai, Siqin / Oguri, Kazuo / Kato, Yoshihiro / Matsumoto, Ichie / Kawase, Harumi / Matsuoka, Toshio

    Journal of sports science & medicine

    2005  Volume 4, Issue 1, Page(s) 9–17

    Abstract: The aim of the present study was to examine the effects of endurance training on heart rate (HR) recovery after exercise and cardiac autonomic nervous system (ANS) modulation in female marathon runners by comparing with untrained controls. Six female ... ...

    Abstract The aim of the present study was to examine the effects of endurance training on heart rate (HR) recovery after exercise and cardiac autonomic nervous system (ANS) modulation in female marathon runners by comparing with untrained controls. Six female marathon runners (M group) aged 32-40 years and eight age-matched untrained females (C group) performed a maximum-effort treadmill running exercise. Maximal oxygen uptake (VO2max) was measured during the exercise with a gas analyzer connected to subjects through a face mask. Heart rate, blood pressure and blood lactate were measured before and after the exercise. Rating of perceived exertion (RPE) to the exercise was obtained immediately after the exercise. Holter ECG was recorded and analyzed with power spectral analysis of heart rate variability (HRV) to investigate the cardiac ANS modulation. The M group had significantly higher VO2max, faster HR recovery after exercise, higher Mean RR, SDRR, HF power and lower LF/HF ratio at rest compared with the C group. The M group also presented greater percent decrease of blood pressure after exercise, although their blood pressure after exercise was higher than the C group. It is suggested that endurance training induced significant alterations in cardiac ANS modulation at rest and significant acceleration of HR recovery after exercise in female marathon runners. Faster HR recovery after exercise in the female marathon runners should result from their higher levels of HRV, higher aerobic capacity and exaggerated blood pressure response to exercise compared with untrained controls. Key PointsThe effects of endurance training on HR recovery after exercise and cardiac ANS modulation were investigated in female marathon runners by comparing with untrained controls.Time and frequency domain analysis of HRV was used to investigate cardiac ANS modulation.As compared with untrained controls, the female marathon runners showed faster HR recovery after exercise, which should result from their higher levels of HRV, higher aerobic capacity and exaggerated blood pressure response to exercise.
    Language English
    Publishing date 2005-03-01
    Publishing country Turkey
    Document type Journal Article
    ISSN 1303-2968
    ISSN 1303-2968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Effect of moderate altitude on peripheral muscle oxygenation during leg resistance exercise in young males.

    Oguri, Kazuo / Du, Na / Kato, Yoshihiro / Miyamoto, Kei / Masuda, Takahiro / Shimizu, Katsuji / Matsuoka, Toshio

    Journal of sports science & medicine

    2004  Volume 3, Issue 3, Page(s) 182–189

    Abstract: Training at moderate altitude (~1800m) is often used by athletes to stimulate muscle hypoxia. However, limited date is available on peripheral muscle oxidative metabolism at this altitude (1800AL). The purpose of this study was to determine whether acute ...

    Abstract Training at moderate altitude (~1800m) is often used by athletes to stimulate muscle hypoxia. However, limited date is available on peripheral muscle oxidative metabolism at this altitude (1800AL). The purpose of this study was to determine whether acute exposure to 1800AL alters muscle oxygenation in the vastus lateralis muscle during resistance exercise. Twenty young active male subjects (aged 16 - 21 yr) performed up to 50 repetitions of the parallel squat at 1800AL and near sea level (SL). They performed the exercise protocol within 3 h after arrival at 1800 AL. During the exercise, the changes in oxygenated hemoglobin (OxyHb) in the vastus lateralis muscle, arterial oxygen saturation (SpO2), and heart rate were measured using near infrared continuous wave spectroscopy (NIRcws) and pulse oximetry, respectively. Changes in OxyHb were expressed by Deff defined as the relative index of the maximum change ratio (%) from the resting level. OxyHb in the vastus lateralis muscle decreased dramatically from the resting level immediately after the start of exercise at both altitudes. The Deff during exercise was significantly (p < 0.001) lower at 1800AL (60.4 ± 6.2 %) than at near SL (74.4 ± 7.6 %). SpO2 during exercise was significantly (p < 0.001) lower at 1800AL (92.0 ± 1.7 %) than at near SL (96.7 ± 1.2 %). Differences (SL - 1800AL) in Deff during exercise correlated fairly strongly with differences in SpO2 during exercise (r = 0.660). These results suggested that acute exposure to moderate altitude caused a more dramatical decrease in peripheral muscle oxygenation during leg resistance exercise. It is salient to note, therefore, that peripheral muscle oxygenation status at moderate altitude could be evaluated using NIRcws and that moderate altitudes might be effectively used to apply hypoxic stress on peripheral muscles. Key PointsThe change in muscle oxygenation during the parallel squat at 1800 altitude and near sea level was investigated using near infrared continuous wave spectroscopy (NIRcws)The muscle oxygenation during exercise at 1800 altitude decreased more dramatically compared to sea level.NIRcws could help to provide a better understanding of exercising muscle metabolism at moderate altitude.
    Language English
    Publishing date 2004-09-01
    Publishing country Turkey
    Document type Journal Article
    ISSN 1303-2968
    ISSN 1303-2968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Pronounced muscle deoxygenation during supramaximal exercise under simulated hypoxia in sprint athletes.

    Oguri, Kazuo / Fujimoto, Hajime / Sugimori, Hiroyuki / Miyamoto, Kei / Tachi, Toshiki / Nagasaki, Sachio / Kato, Yoshihiro / Matsuoka, Toshio

    Journal of sports science & medicine

    2008  Volume 7, Issue 4, Page(s) 512–519

    Abstract: The purpose of this study was to determine whether acute hypoxia alters the deoxygenation level in vastus lateralis muscle during a 30 s Wingate test, and to compare the muscle deoxygenation level between sprint athletes and untrained men. Nine male ... ...

    Abstract The purpose of this study was to determine whether acute hypoxia alters the deoxygenation level in vastus lateralis muscle during a 30 s Wingate test, and to compare the muscle deoxygenation level between sprint athletes and untrained men. Nine male track sprinters (athletic group, VO2max 62.5 ± 4.1 ml/kg/min) and 9 healthy untrained men (untrained group, VO2max 49.9 ± 5.2 ml·kg(-1)·min(-1)) performed a 30 s Wingate test under simulated hypoxic (FIO2 = 0.164 and PIO2 = 114 mmHg) and normoxic conditions. During the exercise, changes in oxygenated hemoglobin (OxyHb) in the vastus lateralis were measured using near infrared continuous wave spectroscopy. Decline in OxyHb, that is muscle deoxygenation, was expressed as percent change from baseline. Percutaneous arterial oxygen saturation (SpO2), oxygen uptake (VO2), and ventilation (VE) were measured continuously. In both groups, there was significantly greater muscle deoxygenation, lower SpO2, lower peakVO2, and higher peakVE during supramaximal exercise under hypoxia than under normoxia, but no differences in peak and mean power output during the exercise. Under hypoxia, the athletic group experienced significantly greater muscle deoxygenation, lower SpO2, greater decrement in peakVO2 and increment in peakVE during the exercise than the untrained group. When the athletic and untrained groups were pooled, the increment of muscle deoxygenation was strongly correlated with lowest SpO2 in the 30 s Wingate test under hypoxia. These results suggest that acute exposure to hypoxia causes a greater degree of peripheral muscle deoxygenation during supramaximal exercise, especially in sprint athletes, and this physiological response would be explained mainly by lower arterial oxygen saturation. Key pointsThe deoxygenation trends in the vastus lateralis muscle during 30 s Wingate test in track sprinters and untrained men under simulated hypoxic and normoxic conditions was investigated using near infrared spectroscopy.Acute hypoxia caused a greater degree of peripheral muscle deoxygenation than normoxia, whereas there were no changes in performance such as power output during 30 s Wingate test.Sprint athletes show a greater degree of peripheral muscle deoxygenation during 30 s Wingate test in hypoxia when compared with untrained subjects.A larger difference in muscle deoxygenation between hypoxia and normoxia is accompanied by lowest SpO2 at the 30 s Wingate test in hypoxia.
    Language English
    Publishing date 2008-12-01
    Publishing country Turkey
    Document type Journal Article
    ISSN 1303-2968
    ISSN 1303-2968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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