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  1. Article ; Online: Expression patterns of members of the isocitrate dehydrogenase gene family in murine inner ear.

    Kim, Y-R / Kim, K-H / Lee, S / Oh, S-K / Park, J-W / Lee, K-Y / Baek, J-I / Kim, U-K

    Biotechnic & histochemistry : official publication of the Biological Stain Commission

    2017  Volume 92, Issue 7, Page(s) 536–544

    Abstract: Age-related hearing loss (ARHL) is characterized by an age-dependent decline of auditory function characterized by with loss of sensory hair cells, spiral ganglion neurons, and stria vascularis (SV) cells in the cochlea of the inner ear. Aging and age- ... ...

    Abstract Age-related hearing loss (ARHL) is characterized by an age-dependent decline of auditory function characterized by with loss of sensory hair cells, spiral ganglion neurons, and stria vascularis (SV) cells in the cochlea of the inner ear. Aging and age-related diseases result from accumulated oxidative damage caused by reactive oxygen species (ROS) generated by mitochondria. The isocitrate dehydrogenase (IDH) family includes three enzymes in human cells: IDH1, IDH2, and IDH3. Although all three enzymes catalyze the same enzymatic reaction, that is, oxidative decarboxylation of isocitrate to produce α-ketoglutarate, each IDH enzyme has unique features. We identified and characterized IDH expression in the cochlea and vestibule of the murine inner ear. We examined the mRNA expression levels of Idh family members in the cochlea and vestibule using reverse transcription-PCR (RT-PCR) and detected expression of IDH family members in both tissues. We also used immunohistochemistry to localize IDH family members within the cochlea and vestibule of the adult mouse inner ear. IDH1 was detected throughout the cochlea. IDH2 was expressed specifically in the hair cells, spiral ganglion, and stria vascularis. IDH3α was found in the cell bodies of neurons of the spiral ganglion, the stria vascularis, and in types II, IV, and V cells of the spiral ligament in a pattern that resembled the location of the Na
    MeSH term(s) Animals ; Ear, Inner/enzymology ; Ear, Inner/metabolism ; Female ; Humans ; Immunohistochemistry ; Isocitrate Dehydrogenase/genetics ; Isocitrate Dehydrogenase/metabolism ; Male ; Mice ; Reverse Transcriptase Polymerase Chain Reaction
    Chemical Substances Isocitrate Dehydrogenase (EC 1.1.1.41) ; isocitrate dehydrogenase 2, mouse (EC 1.1.1.41)
    Language English
    Publishing date 2017-09-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1069349-x
    ISSN 1473-7760 ; 1052-0295
    ISSN (online) 1473-7760
    ISSN 1052-0295
    DOI 10.1080/10520295.2017.1367034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ub I Zs.101: Show issues Location:
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  2. Article: Failure analysis of InGaN/GaN high power light-emitting diodes fabricated with ITO transparent p-type electrode during accelerated electro-thermal stress.

    Moon, Seong Min / Kim, Y D / Oh, S K / Park, M J / Kwak, Joon Seop

    Journal of nanoscience and nanotechnology

    2012  Volume 12, Issue 5, Page(s) 4177–4180

    Abstract: We have investigated the high-temperature degradation of optical power as well as electrical properties of InGaN/GaN light-emitting diodes (LEDs) fabricated with ITO transparent p-electrode during accelerated electro-thermal stress. As the thermal stress ...

    Abstract We have investigated the high-temperature degradation of optical power as well as electrical properties of InGaN/GaN light-emitting diodes (LEDs) fabricated with ITO transparent p-electrode during accelerated electro-thermal stress. As the thermal stress increased from 150 degrees C to 250 degrees C at a electrical stress of 200 mA, the optical power of the LEDs was significantly reduced. Degradation of the optical power was thermally activated, with the activation of 0.9 eV. In addition, the activation energy of the degradation of optical power was fairly similar to that of the degradation of series resistance of the LEDs, 1.0 eV, which implies that the increase in the series resistance may result in the severe degradation of optical power. We also showed that the increase in the series resistance of the LEDs during the accelerated electro-thermal stress can be attributed to reduction of the active acceptor concentration in the p-type semiconductor layers and local joule heating due to the current crowding.
    Language English
    Publishing date 2012-05-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1533-4880
    ISSN 1533-4880
    DOI 10.1166/jnn.2012.5938
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Experimental basis for cancer prevention by vitamin E.

    Shklar, G / Oh, S K

    Cancer investigation

    2000  Volume 18, Issue 3, Page(s) 214–222

    Abstract: Recent clinical trials have demonstrated the significant cancer preventive potential of vitamin E in many different cancer sites, ranging from oral and pharyngeal cancer to prostate cancer. There is an extensive experimental basis for this clinical ... ...

    Abstract Recent clinical trials have demonstrated the significant cancer preventive potential of vitamin E in many different cancer sites, ranging from oral and pharyngeal cancer to prostate cancer. There is an extensive experimental basis for this clinical cancer inhibition. The experimental background includes animal studies (experimental pathology, immunology and molecular biology, synergism, selectivity and safety), in vitro biochemical studies, and human studies (epidemiology and biomarkers, prevention of many pathologic entities other than cancer).
    MeSH term(s) Animals ; Biomarkers, Tumor ; Disease Models, Animal ; Epidemiologic Studies ; Humans ; Neoplasms/prevention & control ; Neoplasms, Experimental/prevention & control ; Vitamin E/pharmacology ; Vitamin E/therapeutic use
    Chemical Substances Biomarkers, Tumor ; Vitamin E (1406-18-4)
    Language English
    Publishing date 2000
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 604942-4
    ISSN 0735-7907
    ISSN 0735-7907
    DOI 10.3109/07357900009031826
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1862: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: Hyperkalaemia induced complete atrioventricular block with a narrow QRS complex.

    Kim, N-H / Oh, S K / Jeong, J-W

    Heart (British Cardiac Society)

    2005  Volume 91, Issue 1, Page(s) e5

    MeSH term(s) Aged ; Electrocardiography ; Female ; Heart Block/etiology ; Heart Block/physiopathology ; Humans ; Hyperkalemia/complications
    Language English
    Publishing date 2005-01
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/hrt.2004.046524
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.MO 112: Show issues

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  5. Article: Expression of cucumber LOX genes in response to powdery mildew and defense-related signal molecules

    Oh, S.-K. / Jang, H. A. / Kim, J. / Choi, D. / Park, Y.-L. / Kwon, S.-Y.

    Canadian journal of plant science

    2014  Volume 94, Issue 5, Page(s) 845–850

    Document type Article
    ISSN 0008-4220
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 800 a: Show issues

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  6. Article: Effect of sodium azide on peroxyoxalate chemiluminescence assay method.

    Oh, S K / Cha, S H

    Analytical biochemistry

    1994  Volume 218, Issue 1, Page(s) 222–224

    MeSH term(s) Azides/pharmacology ; Catalysis ; Indicators and Reagents/pharmacology ; Luminescent Measurements ; Oxalates/chemistry ; Sodium Azide
    Chemical Substances Azides ; Indicators and Reagents ; Oxalates ; peroxyoxalate (5796-84-9) ; Sodium Azide (968JJ8C9DV)
    Language English
    Publishing date 1994-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1110-1
    ISSN 1096-0309 ; 0003-2697
    ISSN (online) 1096-0309
    ISSN 0003-2697
    DOI 10.1006/abio.1994.1163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 389: Show issues Location:
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  7. Article: Interaction of antiparallel transverse domain walls in ferromagnetic nanowires.

    Djuhana, D / Piao, H-G / Shim, J-H / Lee, S-H / Oh, S K / Yu, S-C / Kim, D-H

    Journal of nanoscience and nanotechnology

    2011  Volume 11, Issue 7, Page(s) 6237–6240

    Abstract: The interaction of antiparallel transverse domain walls in ferromagnetic nanowires was investigated via micromagnetic simulation with systematic variations of the external field strength as well as the wire thickness. The interaction of antiparallel ... ...

    Abstract The interaction of antiparallel transverse domain walls in ferromagnetic nanowires was investigated via micromagnetic simulation with systematic variations of the external field strength as well as the wire thickness. The interaction of antiparallel transverse walls after domain wall collision exhibited damped multiple collisions due to the rigid structure of the antiparallel transverse walls. The detailed process during the multiple collisions was analyzed via the Fast Fourier Transform technique, along with a careful examination of the inner spin structures of the colliding domain walls. It was found that a frequency peak of multiple collisions shifted to a higher peak position as the external field strength increases. With a stronger field strength of around a few hundred mT, it was found that two antiparallel transverse walls were finally annihilated with formation of complex antivortex structures.
    Language English
    Publishing date 2011-10-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1533-4880
    ISSN 1533-4880
    DOI 10.1166/jnn.2011.4485
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Gene regulation: translational initiation by internal ribosome binding.

    Oh, S K / Sarnow, P

    Current opinion in genetics & development

    1993  Volume 3, Issue 2, Page(s) 295–300

    Abstract: During the past year, several examples of cellular mRNAs have been described in which translational initiation occurs by internal ribosome binding, a mechanism hitherto thought to be restricted to picornaviral RNAs. New insights into the molecular ... ...

    Abstract During the past year, several examples of cellular mRNAs have been described in which translational initiation occurs by internal ribosome binding, a mechanism hitherto thought to be restricted to picornaviral RNAs. New insights into the molecular mechanism of internal ribosome entry have been provided by the structural and functional analyses of both the internal ribosome entry sites and the protein factors that stimulate translation mediated by these elements.
    MeSH term(s) Animals ; Antennapedia Homeodomain Protein ; Base Sequence ; Binding Sites ; DNA-Binding Proteins/genetics ; Drosophila Proteins ; Drosophila melanogaster/genetics ; Gene Expression Regulation ; Gene Expression Regulation, Viral ; Homeodomain Proteins ; Molecular Sequence Data ; Nuclear Proteins ; Peptide Chain Initiation, Translational ; RNA Viruses/genetics ; RNA, Messenger/metabolism ; RNA, Viral/metabolism ; Regulatory Sequences, Nucleic Acid ; Ribosomes/metabolism ; Transcription Factors
    Chemical Substances Antennapedia Homeodomain Protein ; Antp protein, Drosophila ; DNA-Binding Proteins ; Drosophila Proteins ; Homeodomain Proteins ; Nuclear Proteins ; RNA, Messenger ; RNA, Viral ; Transcription Factors
    Keywords covid19
    Language English
    Publishing date 1993-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 1077312-5
    ISSN 1879-0380 ; 0959-437X
    ISSN (online) 1879-0380
    ISSN 0959-437X
    DOI 10.1016/0959-437x(93)90037-p
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3240: Show issues Location:
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  9. Article: Three-dimensional spin configuration of ferromagnetic nanocubes.

    Piao, H-G / Djuhana, D / Shim, J-H / Lee, S-H / Jun, S-H / Oh, S K / Yu, S-C / Kim, D-H

    Journal of nanoscience and nanotechnology

    2010  Volume 10, Issue 11, Page(s) 7212–7216

    Abstract: We have systematically investigated three-dimensional spin configurations in ferromagnetic nanocubes using micromagnetic simulation with variation of cube geometry. For thin cuboids, a spin configuration exhibits a four-domain Landau state with a ... ...

    Abstract We have systematically investigated three-dimensional spin configurations in ferromagnetic nanocubes using micromagnetic simulation with variation of cube geometry. For thin cuboids, a spin configuration exhibits a four-domain Landau state with a magnetic vortex structure at the center as in the case of a thin film square. For a thick cube, a complex spin configuration with an S-type cylindrically asymmetric vortex having two cores on a pair of surfaces while a leaf-like and a C-type states are observed on the other two pairs of cube surfaces. Competition between the geometrical symmetry and magnetic energy minimization condition in ferromagnetic nanocubes leads to the complex spin structure with a spontaneously broken symmetry.
    Language English
    Publishing date 2010-08-10
    Publishing country United States
    Document type Journal Article
    ISSN 1533-4880
    ISSN 1533-4880
    DOI 10.1166/jnn.2010.2760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Reduction of gate leakage current on AlGaN/GaN high electron mobility transistors by electron-beam irradiation.

    Oh, S K / Song, C G / Jang, T / Kim, Kwang-Choong / Jo, Y J / Kwak, J S

    Journal of nanoscience and nanotechnology

    2010  Volume 13, Issue 3, Page(s) 1738–1740

    Abstract: This study examined the effect of electron-beam (E-beam) irradiation on the AIGaN/GaN HEMTs for the reduction of gate leakage. After E-beam irradiation, the gate leakage current significantly decreased from 2.68 x 10(-8) A to 4.69 x 10(-9) A at a drain ... ...

    Abstract This study examined the effect of electron-beam (E-beam) irradiation on the AIGaN/GaN HEMTs for the reduction of gate leakage. After E-beam irradiation, the gate leakage current significantly decreased from 2.68 x 10(-8) A to 4.69 x 10(-9) A at a drain voltage of 10 V. The maximum drain current density of the AIGaN/GaN HEMTs with E-beam irradiation increased 14%, and the threshold voltage exhibited a negative shift, when compared to that of the AIGaN/GaN HEMTs before E-beam irradiation. These results strongly suggest that the reduction of gate leakage current resulted from neutralization nitrogen vacancies and removing of oxygen impurities.
    Language English
    Publishing date 2010-11-30
    Publishing country United States
    Document type Journal Article
    ISSN 1533-4880
    ISSN 1533-4880
    DOI 10.1166/jnn.2013.6987
    Database MEDical Literature Analysis and Retrieval System OnLINE

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