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  1. Book: Prevention of late life depression

    Okereke, Olivia I.

    current clinical challenges and priorities

    (Aging medicine)

    2015  

    Title variant Prevention of late-life depression
    Author's details Olivia I. Okereke ed
    Series title Aging medicine
    Keywords Late-Life Depression ; Social Risk Factors ; Behavioral Risk Factors ; Medical Co-Morbidities of Depression ; Social Isolation ; Fragility
    Language English
    Size X, 191 S. : Ill., graph. Darst., Kt., 235 mm x 155 mm
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT018675833
    ISBN 978-3-319-16044-3 ; 3-319-16044-3 ; 9783319160450 ; 3319160451
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: The Challenging Task of Addressing the Role of Vitamin D in Late-life Depression: Considerations of Measures, Confounders, Mediators, and Moderators.

    Okereke, Olivia I

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2018  Volume 26, Issue 11, Page(s) 1144–1146

    MeSH term(s) Aged ; Depression ; Depressive Disorder ; Humans ; Vitamin D
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2018-08-25
    Publishing country England
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2018.08.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Re-remembering the influence of randomized β-carotene on cognitive decline.

    Kopec, Rachel E / Chasman, Daniel I / Okereke, Olivia I / Sesso, Howard D

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    2023  Volume 19, Issue 8, Page(s) 3718–3721

    Abstract: The wave of individuals impacted by dementia continues to rise rapidly as worldwide lifespan increases. Dietary strategies to slow cognitive decline and prolong time to clinical dementia remain understudied, but with potentially powerful public health ... ...

    Abstract The wave of individuals impacted by dementia continues to rise rapidly as worldwide lifespan increases. Dietary strategies to slow cognitive decline and prolong time to clinical dementia remain understudied, but with potentially powerful public health consequences. Indeed, previously conducted large, randomized, placebo-controlled trials of micronutrients remain an under-leveraged resource to study changes in cognitive performance. As a motivating example, we highlight an ancillary report from the Physicians' Health Study, where subjects randomized to β-carotene (a provitamin A carotenoid) had a more attenuated change in longitudinal global cognitive performance and verbal memory, as compared to subjects randomized to placebo. Despite mechanistic evidence from cell and animal studies supporting a vitamin A-mediated role in the biology associated with cognition, limited follow-up work has been conducted. We argue that dietary factors (including provitamin A) deserve a second look, leveraging multi-omic approaches, to elucidate how they may mitigate cognitive decline and dementia risk.
    MeSH term(s) Humans ; beta Carotene/therapeutic use ; Provitamins/therapeutic use ; Cognitive Dysfunction/drug therapy ; Cognition ; Dementia ; Alzheimer Disease/drug therapy
    Chemical Substances beta Carotene (01YAE03M7J) ; Provitamins
    Language English
    Publishing date 2023-03-20
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2211627-8
    ISSN 1552-5279 ; 1552-5260
    ISSN (online) 1552-5279
    ISSN 1552-5260
    DOI 10.1002/alz.13018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effect of Long-term Supplementation With Marine Omega-3 Fatty Acids vs Placebo on Risk of Depression-Reply.

    Okereke, Olivia I / Mischoulon, David / Manson, JoAnn E

    JAMA

    2022  Volume 327, Issue 13, Page(s) 1292

    MeSH term(s) Depression/drug therapy ; Depression/prevention & control ; Dietary Supplements ; Double-Blind Method ; Fatty Acids, Omega-3/therapeutic use
    Chemical Substances Fatty Acids, Omega-3
    Language English
    Publishing date 2022-04-05
    Publishing country United States
    Document type Clinical Study ; Journal Article ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2022.2033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Late-Life Depression: A Narrative Review on Risk Factors and Prevention.

    Vyas, Chirag M / Okereke, Olivia I

    Harvard review of psychiatry

    2020  Volume 28, Issue 2, Page(s) 72–99

    Abstract: Learning objectives: After participating in this activity, learners should be better able to:• Identify risk factors for late-life depression• Evaluate strategies to prevent late-life depression ABSTRACT: Late-life depression (LLD) is one of the major ... ...

    Abstract Learning objectives: After participating in this activity, learners should be better able to:• Identify risk factors for late-life depression• Evaluate strategies to prevent late-life depression ABSTRACT: Late-life depression (LLD) is one of the major sources of morbidity and mortality in the world. Because LLD is related to increased public health burden, excess health care costs and utilization, reduced quality of life, and increased mortality, prevention is a priority. Older adults differ from younger adults with respect to key features, such as their chronicity and lifetime burden of depression and their constellation of comorbidities and risk factors. LLD likely arises from a complex interplay of risk factors, including medical, physiologic, psychosocial, behavioral, and environmental factors. Thus, a comprehensive understanding of LLD risk factors is necessary to inform prevention strategies. In this narrative literature review, we address both the risk architecture of LLD and several potential strategies for prevention. Our description of LLD risk factors and prevention approaches is informed by the framework developed by the National Academy of Medicine (formerly, Institute of Medicine), which includes indicated, selective, and universal approaches to prevention.
    MeSH term(s) Aging/psychology ; Comorbidity ; Depression/prevention & control ; Humans ; Primary Prevention/methods ; Randomized Controlled Trials as Topic ; Risk Factors
    Language English
    Publishing date 2020-02-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1174775-4
    ISSN 1465-7309 ; 1067-3229
    ISSN (online) 1465-7309
    ISSN 1067-3229
    DOI 10.1097/HRP.0000000000000240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: More Evidence of an Inverse Association Between Cancer and Alzheimer Disease.

    Okereke, Olivia I / Meadows, Mary-Ellen

    JAMA network open

    2019  Volume 2, Issue 6, Page(s) e196167

    MeSH term(s) Alzheimer Disease ; Humans ; Memory ; Morbidity ; Neoplasms
    Language English
    Publishing date 2019-06-05
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2019.6167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: From Diversity, Equity, and Inclusion to an Antiracism Strategic Plan: An Academic Department of Psychiatry's Journey.

    Trinh, Nhi-Ha T / Talukder, Farhabi / Nagendra, Arun / Ali, Areeba M / Emmerich, Anne / Chow, Louis / Jenkins, Jonathan H / Okereke, Olivia I

    Psychiatric services (Washington, D.C.)

    2024  Volume 75, Issue 4, Page(s) 391–394

    Abstract: The efforts of an academic psychiatry department to embark on an antiracism strategic planning process are outlined, including the establishment of an antiracism task force charged with the development of an antiracism strategic plan. The initial process ...

    Abstract The efforts of an academic psychiatry department to embark on an antiracism strategic planning process are outlined, including the establishment of an antiracism task force charged with the development of an antiracism strategic plan. The initial process of the task force is described, recommendations are summarized, and future directions are outlined.
    MeSH term(s) Humans ; Antiracism ; Diversity, Equity, Inclusion ; Organizations ; Psychiatry ; Racism
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1220173-x
    ISSN 1557-9700 ; 1075-2730
    ISSN (online) 1557-9700
    ISSN 1075-2730
    DOI 10.1176/appi.ps.20230024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Vitamin D and Psychosis in Alzheimer Disease: New Insights From Pharmacogenomics Research.

    Vyas, Chirag M / Okereke, Olivia I

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2019  Volume 27, Issue 9, Page(s) 918–919

    MeSH term(s) Alzheimer Disease ; Humans ; Pharmacogenetics ; Psychotic Disorders ; Vitamin D
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2019-06-04
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2019.05.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Child Maltreatment Among Older Adults: A Narrative Review of Psychotherapeutic Interventions and Clinical Considerations.

    Ishikawa, Rachel Zack / Ander, Ilana / Popescu, Dominique L / Vyas, Chirag M / Okereke, Olivia I

    Clinical gerontologist

    2023  , Page(s) 1–15

    Abstract: Objectives: The goals of this narrative review are to review the literature on psychotherapeutic interventions for older adults with histories of child maltreatment (CM) and to examine the unique considerations for assessing, diagnosing, and treating ... ...

    Abstract Objectives: The goals of this narrative review are to review the literature on psychotherapeutic interventions for older adults with histories of child maltreatment (CM) and to examine the unique considerations for assessing, diagnosing, and treating older adults with CM histories.
    Methods: Online database searches were conducted to identify the extant research into the efficacy of psychotherapeutic interventions for older adults with CM-related trauma.
    Results: Eight studies met inclusion criteria. The primary target diagnoses were post-traumatic stress disorder and depression. Psychotherapeutic interventions included Narrative Exposure Therapy, exposure-based treatments, Life Review Therapy, integrated treatments, and a spiritually-focused group therapy.
    Conclusions: While limited in number and generalizability due to study design and sample size and characteristics, the studies provide preliminary evidence of potentially effective psychotherapeutic treatments for older adults with CM histories. Further research is needed to determine the most effective psychotherapeutic interventions for this population.
    Clinical implications: Many older adults suffer for decades with the repercussions of CM. Due to knowledge gaps regarding best practices for treating older adults with CM histories, many clinicians are poorly equipped to treat this population. Therefore, awareness of CM-related pathology and familiarity with effective psychotherapeutic interventions are essential for clinicians to meet the needs of this population.
    Language English
    Publishing date 2023-05-31
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 226146-7
    ISSN 1545-2301 ; 0731-7115
    ISSN (online) 1545-2301
    ISSN 0731-7115
    DOI 10.1080/07317115.2023.2219671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Racial and ethnic diversity in studies of late-life mental health.

    Okereke, Olivia I

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2014  Volume 22, Issue 7, Page(s) 637–641

    MeSH term(s) Aging/psychology ; Cognition Disorders/epidemiology ; Cognition Disorders/ethnology ; Continental Population Groups/psychology ; Cross-Sectional Studies ; Depressive Disorder/epidemiology ; Depressive Disorder/ethnology ; Ethnic Groups/psychology ; Humans ; Longitudinal Studies
    Language English
    Publishing date 2014-07
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2014.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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