Article ; Online: Survey of nonsusceptible nasopharyngeal Streptococcus pneumoniae isolates in children attending day-care centers in Brazil.
The Pediatric infectious disease journal
2010 Volume 29, Issue 1, Page(s) 77–79
Abstract: A survey of nasopharyngeal carriage of penicillin nonsusceptible pneumococcal (PNSp) isolates was conducted among 1192 children attending 62 day care centers in Brazil, where pneumococcal vaccination has not been routinely introduced. Nasopharyngeal ... ...
| Abstract | A survey of nasopharyngeal carriage of penicillin nonsusceptible pneumococcal (PNSp) isolates was conducted among 1192 children attending 62 day care centers in Brazil, where pneumococcal vaccination has not been routinely introduced. Nasopharyngeal pneumococcal carriage was detected in 686 (57.6%) infants, and 178 (25.9%) of them carried PNSp isolates. Being less than 24 months of age, hospitalization in the previous 3 months, and recurrent acute otitis media were independently associated with PNSp. Serotypes 14, 23F, 19A, 6A, 6B and 19F were the most common serotype isolated accounting for 80% of the PNSp. A high proportion (35/332) of non-(sero)typeable isolates was detected, 62.9% of them PNSp. Serotypes coverage projected for the pneumococcal conjugate vaccine (PCV) 13-valent vaccine (72%) was significantly higher compared with PCV7 (58.4%) and PCV 10-valent vaccine (59.3%). |
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| MeSH term(s) | Bacterial Typing Techniques ; Brazil/epidemiology ; Carrier State/epidemiology ; Carrier State/microbiology ; Child Day Care Centers ; Child, Preschool ; Cross-Sectional Studies ; Female ; Hospitalization/statistics & numerical data ; Humans ; Infant ; Male ; Nasopharynx/microbiology ; Otitis Media/epidemiology ; Penicillin Resistance ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/microbiology ; Prevalence ; Recurrence ; Serotyping ; Streptococcus pneumoniae/classification ; Streptococcus pneumoniae/drug effects ; Streptococcus pneumoniae/isolation & purification | |||||
| Language | English | |||||
| Publishing date | 2010-01-02 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't | |||||
| ZDB-ID | 392481-6 | |||||
| ISSN | 1532-0987 ; 0891-3668 | |||||
| ISSN (online) | 1532-0987 | |||||
| ISSN | 0891-3668 | |||||
| DOI | 10.1097/INF.0b013e3181af7e90 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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