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  1. Article ; Online: Assessment of time-dependent white blood cells degeneration induced by blood storage on automated parameters and morphology examination.

    Naoum, Flávio Augusto / Martin, Fernando Henrique de Oliveira / Valejo, Mariana Ramirez / Oliveira, Maria Gabriela de Lucca

    International journal of laboratory hematology

    2020  Volume 42, Issue 4, Page(s) e185–e188

    MeSH term(s) Adult ; Blood Preservation ; Female ; Humans ; Leukocyte Count ; Leukocytes/cytology ; Leukocytes/metabolism ; Male ; Specimen Handling
    Language English
    Publishing date 2020-05-31
    Publishing country England
    Document type Evaluation Study ; Letter
    ZDB-ID 2268590-X
    ISSN 1751-553X ; 1751-5521 ; 0141-9854
    ISSN (online) 1751-553X
    ISSN 1751-5521 ; 0141-9854
    DOI 10.1111/ijlh.13234
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1499: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Estimated glomerular filtration rate in clinical practice: Consensus positioning of the Brazilian Society of Nephrology (SBN) and Brazilian Society of Clinical Pathology and Laboratory Medicine (SBPC/ML).

    Kirsztajn, Gianna Mastroianni / Silva Junior, Geraldo Bezerra da / Silva, Artur Quintiliano Bezerra da / Abensur, Hugo / Romão Junior, João Egídio / Bastos, Marcus Gomes / Calice-Silva, Viviane / Carmo, Lilian Pires de Freitas do / Sandes-Freitas, Tainá Veras de / Abreu, Patrícia Ferreira / Andreguetto, Bruna Dolci / Cortes, Luiz Gustavo Ferreira / Oliveira, Maria Gabriela de Lucca / Vieira, Luisane Maria Falci / Moura-Neto, José A / Andriolo, Adagmar

    Jornal brasileiro de nefrologia

    2024  Volume 46, Issue 3, Page(s) e20230193

    Abstract: Chronic kidney disease (CKD) represents one of today's main public health problems. Serum creatinine measurement and estimation of the glomerular filtration rate (GFR) are the main tools for evaluating renal function. There are several equations to ... ...

    Abstract Chronic kidney disease (CKD) represents one of today's main public health problems. Serum creatinine measurement and estimation of the glomerular filtration rate (GFR) are the main tools for evaluating renal function. There are several equations to estimate GFR, and CKD-EPI equation (Chronic Kidney Disease - Epidemiology) is the most recommended one. There are still some controversies regarding serum creatinine measurement and GFR estimation, since several factors can interfere in this process. An important recent change was the removal of the correction for race from the equations for estimating GFR, which overestimated kidney function, and consequently delayed the implementation of treatments such as dialysis and kidney transplantation. In this consensus document from the Brazilian Societies of Nephrology and Clinical Pathology and Laboratory Medicine, the main concepts related to the assessment of renal function are reviewed, as well as possible existing controversies and recommendations for estimating GFR in clinical practice.
    MeSH term(s) Humans ; Glomerular Filtration Rate ; Nephrology ; Creatinine ; Brazil ; Consensus ; Renal Dialysis ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/therapy ; Pathology, Clinical
    Chemical Substances Creatinine (AYI8EX34EU)
    Language Portuguese
    Publishing date 2024-04-05
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2057873-8
    ISSN 2175-8239 ; 2175-8239
    ISSN (online) 2175-8239
    ISSN 2175-8239
    DOI 10.1590/2175-8239-JBN-2023-0193en
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Diagnostic and prognostic utility of WBC counts and cell population data in patients with COVID-19.

    Naoum, Flávio Augusto / Ruiz, Adriana Laridondo Zucareli / Martin, Fernando Henrique de Oliveira / Brito, Tayra Hostalacio Gomes / Hassem, Vitoria / Oliveira, Maria Gabriela de Lucca

    International journal of laboratory hematology

    2020  Volume 43 Suppl 1, Page(s) 124–128

    Abstract: Introduction: Early diagnosis and identification of potential critical cases for timely treatment are crucial for COVID-19 patients. The aim of this study was to analyze the diagnostic and prognostic implications of WBC and cell population data (CPD) ... ...

    Abstract Introduction: Early diagnosis and identification of potential critical cases for timely treatment are crucial for COVID-19 patients. The aim of this study was to analyze the diagnostic and prognostic implications of WBC and cell population data (CPD) abnormalities related to COVID-19 at disease onset.
    Methods: Baseline WBC counts and CPD data were analyzed in one hundred COVID-19 patients presenting to emergency department and subsequently discharged (n=49), admitted (n=51) or deceased (n=22), and in 47 healthy subjects.
    Results: Lymphopenia and eosinopenia were observed in all COVID-19 patients, with more intensity in the admitted and deceased groups, that also presented increased WBC and neutrophil counts. On CPD analysis, COVID-19 was associated with increased volume of neutrophils, lymphocytes, and monocytes, whereas conductivity was decreased for neutrophils and increased for lymphocytes. The ROC curve analysis showed good performance for lymphocyte counts in predicting COVID-19 diagnosis (AUC=0.858), for neutrophil counts in predicting admission for COVID-19 (AUC=0.744) and for monocytes volume in predicting COVID-19 diagnosis (AUC=0.837).
    Conclusion: WBC counts and CPD parameters at disease onset in COVID-19 patients can improve diagnostic characterization and aid in the discrimination between severe and nonsevere presentations.
    MeSH term(s) Adult ; Area Under Curve ; COVID-19/blood ; COVID-19/diagnosis ; COVID-19/mortality ; COVID-19 Testing ; Electric Conductivity ; Flow Cytometry ; Humans ; Inpatients ; Leukocyte Count ; Outpatients ; Pandemics ; Prognosis ; ROC Curve ; Retrospective Studies ; Risk ; SARS-CoV-2 ; Sensitivity and Specificity ; Survival Analysis
    Keywords covid19
    Language English
    Publishing date 2020-11-15
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 2268590-X
    ISSN 1751-553X ; 1751-5521 ; 0141-9854
    ISSN (online) 1751-553X
    ISSN 1751-5521 ; 0141-9854
    DOI 10.1111/ijlh.13395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1499: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Diagnostic and prognostic utility of WBC counts and cell population data in patients with COVID-19

    Naoum, Flávio Augusto / Ruiz, Adriana Laridondo Zucareli / Martin, Fernando Henrique de Oliveira / Brito, Tayra Hostalacio Gomes / Hassem, Vitoria / Oliveira, Maria Gabriela de Lucca

    Int. j. lab. hematol

    Abstract: INTRODUCTION: Early diagnosis and identification of potential critical cases for timely treatment are crucial for COVID-19 patients. The aim of this study was to analyze the diagnostic and prognostic implications of WBC and cell population data (CPD) ... ...

    Abstract INTRODUCTION: Early diagnosis and identification of potential critical cases for timely treatment are crucial for COVID-19 patients. The aim of this study was to analyze the diagnostic and prognostic implications of WBC and cell population data (CPD) abnormalities related to COVID-19 at disease onset. METHODS: Baseline WBC counts and CPD data were analyzed in one hundred COVID-19 patients presenting to emergency department and subsequently discharged (n = 49), admitted (n = 51) or deceased (n = 22), and in 47 healthy subjects. RESULTS: Lymphopenia and eosinopenia were observed in all COVID-19 patients, with more intensity in the admitted and deceased groups, that also presented increased WBC and neutrophil counts. On CPD analysis, COVID-19 was associated with increased volume of neutrophils, lymphocytes, and monocytes, whereas conductivity was decreased for neutrophils and increased for lymphocytes. The ROC curve analysis showed good performance for lymphocyte counts in predicting COVID-19 diagnosis (AUC = 0.858), for neutrophil counts in predicting admission for COVID-19 (AUC = 0.744) and for monocytes volume in predicting COVID-19 diagnosis (AUC = 0.837). CONCLUSION: WBC counts and CPD parameters at disease onset in COVID-19 patients can improve diagnostic characterization and aid in the discrimination between severe and nonsevere presentations.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #926858
    Database COVID19

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