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  1. Article: Determination of multi-class pesticides residues of cow and human milk samples from Iran using UHPLC-MS/MS and GC-ECD: A probabilistic health risk assessment

    Ramezani, Sara / Mahdavi, Vahideh / Gordan, Hasti / Rezadoost, Hasan / Oliver Conti, Gea / Mousavi Khaneghah, Amin

    Environmental research. 2022 May 15, v. 208

    2022  

    Abstract: Raw, pasteurized, powdered cow milk and human milk samples from Tehran, Iran were investigated for the residual of fifty pesticides with the aid of gas chromatography coupled with electron capture detector (GC-ECD) and mass detector for confirmation; and ...

    Abstract Raw, pasteurized, powdered cow milk and human milk samples from Tehran, Iran were investigated for the residual of fifty pesticides with the aid of gas chromatography coupled with electron capture detector (GC-ECD) and mass detector for confirmation; and ultra-high performance liquid chromatography-tandem mass spectroscopy (UHPLC-MS/MS). No pesticide residue was determined in more than 91% of examined samples. However, the dimethoate residue was detected in 3 raw milk samples in levels higher than EU recommended MRL. While in 3 human milk samples, organochlorine pesticides residue, p,p′-DDT, and p,p′-DDD was recognized below MRLs, only in 1 human sample residue of p,p′-DDE was more than CODEX recommended MRL. HI in adults and children were 0.72 and 3.55, respectively. However, the health risk assessment based on HI demonstrated that adult consumers are not at considerable risk. The HI, higher than 1 in children, confirms the risks raised due to ingestion of organochlorine (OCP) and organophosphorus (OPP) pesticides via milk consumption. In addition, no carcinogenic risk to milk consumers was calculated. Therefore, implementation of good farming practices on farms, improving the knowledge and consciousness of pesticide users, use other safe methods for pest control such as biotechnology-based, and use a rational program for application of pesticides, continuous monitoring of pesticides in crops, and strict government regulations on pesticide residues in food are recommended.
    Keywords adults ; breast milk ; carcinogenicity ; chlorinated hydrocarbons ; consciousness ; cows ; dimethoate ; gas chromatography ; health effects assessments ; humans ; ingestion ; liquid chromatography ; milk ; milk consumption ; pest control ; pesticide residues ; raw milk ; research ; risk ; Iran
    Language English
    Dates of publication 2022-0515
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2022.112730
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Determination of multi-class pesticides residues of cow and human milk samples from Iran using UHPLC-MS/MS and GC-ECD: A probabilistic health risk assessment.

    Ramezani, Sara / Mahdavi, Vahideh / Gordan, Hasti / Rezadoost, Hasan / Oliver Conti, Gea / Mousavi Khaneghah, Amin

    Environmental research

    2022  Volume 208, Page(s) 112730

    Abstract: Raw, pasteurized, powdered cow milk and human milk samples from Tehran, Iran were investigated for the residual of fifty pesticides with the aid of gas chromatography coupled with electron capture detector (GC-ECD) and mass detector for confirmation; and ...

    Abstract Raw, pasteurized, powdered cow milk and human milk samples from Tehran, Iran were investigated for the residual of fifty pesticides with the aid of gas chromatography coupled with electron capture detector (GC-ECD) and mass detector for confirmation; and ultra-high performance liquid chromatography-tandem mass spectroscopy (UHPLC-MS/MS). No pesticide residue was determined in more than 91% of examined samples. However, the dimethoate residue was detected in 3 raw milk samples in levels higher than EU recommended MRL. While in 3 human milk samples, organochlorine pesticides residue, p,p'-DDT, and p,p'-DDD was recognized below MRLs, only in 1 human sample residue of p,p'-DDE was more than CODEX recommended MRL. HI in adults and children were 0.72 and 3.55, respectively. However, the health risk assessment based on HI demonstrated that adult consumers are not at considerable risk. The HI, higher than 1 in children, confirms the risks raised due to ingestion of organochlorine (OCP) and organophosphorus (OPP) pesticides via milk consumption. In addition, no carcinogenic risk to milk consumers was calculated. Therefore, implementation of good farming practices on farms, improving the knowledge and consciousness of pesticide users, use other safe methods for pest control such as biotechnology-based, and use a rational program for application of pesticides, continuous monitoring of pesticides in crops, and strict government regulations on pesticide residues in food are recommended.
    MeSH term(s) Animals ; Cattle ; Chromatography, Gas ; Chromatography, High Pressure Liquid ; Electrons ; Female ; Food Contamination/analysis ; Humans ; Hydrocarbons, Chlorinated/analysis ; Iran ; Milk/chemistry ; Milk, Human/chemistry ; Pesticide Residues/analysis ; Pesticides/analysis ; Risk Assessment ; Tandem Mass Spectrometry/methods
    Chemical Substances Hydrocarbons, Chlorinated ; Pesticide Residues ; Pesticides
    Language English
    Publishing date 2022-01-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2022.112730
    Database MEDical Literature Analysis and Retrieval System OnLINE

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