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Article ; Online: Nourrir les morts – les poteries associées aux défunts dans le cimetière néolithique KDK23 (ve millénaire av. J.-C., Soudan)

Philippe Chambon / Pascal Sellier / Aline Emery-Barbier / Olivier Langlois

Revue d'ethnoécologie, Vol

2021 Volume 19

Abstract: In the area of Kadruka, in Sudanese Nubia, almost twenty Neolithic cemeteries from the Vth millennium BC have been identified. The current excavation at KDK 23 has already provided more than 130 burials, almost all individual. The often plentiful goods ... ...

Abstract	In the area of Kadruka, in Sudanese Nubia, almost twenty Neolithic cemeteries from the Vth millennium BC have been identified. The current excavation at KDK 23 has already provided more than 130 burials, almost all individual. The often plentiful goods consisted in unused objects or even objects made for the funeral itself, except for the ceramic pots that played a specific role. Taken from the household, they are mainly containers; the inclusion of additional items such as spoons, small bowls or feeding bottles, inside pots associated with infants indicates that they indeed contained food for the dead; supplies for the last journey.
Keywords	Nubia ; Neolithic ; cemetery ; food ; pottery ; last journey ; Anthropology ; GN1-890
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	Laboratoire Éco-anthropologie et Ethnobiologie
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: Ressources vivrières et choix alimentaires dans le bassin du lac Tchad

Christine Raimond, Éric Garine, Olivier Langlois (dir.)

2005

Abstract: Ce XIe colloque du réseau de recherche pluridisciplinaire Méga-Tchad traite du thème de l'alimentation dans une région très contrastée, tant du point de vue des sociétés qui la composent que des contextes écologiques, économiques et politiques. Au-delà ... ...

Abstract	Ce XIe colloque du réseau de recherche pluridisciplinaire Méga-Tchad traite du thème de l'alimentation dans une région très contrastée, tant du point de vue des sociétés qui la composent que des contextes écologiques, économiques et politiques. Au-delà de la prise en compte des besoins vitaux des hommes, cet ouvrage considère à la fois la demande spécifique des populations - goûts, choix et stratégies de subsistance -, les systèmes de productions vivrières et les environnements physiques et h..
Size	1 electronic resource ( p.)
Publisher	IRD Éditions
Document type	Book ; Online
Note	French ; Open Access
HBZ-ID	HT020094404
ISBN	9782709915762 ; 9782709918213 ; 2709915766 ; 2709918218
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Territoire et biodiversité

Christine Raimond / Eric Garine / Olivier Langlois

Bulletin de l’Association de Géographes Français, Vol 94, Iss 2, Pp 211-

mises en patrimoine et anticipations des acteurs. Une relecture à partir de la Haute Bénoué (Cameroun)

2017 Volume 227

Abstract: After ten years of implementation of the development plan of the Parc de la Bénoué and the continued immigration of new farmers and herders, what were the evolutions of the territories and the power relations between, on the one hand, indigenous and non- ... ...

Abstract	After ten years of implementation of the development plan of the Parc de la Bénoué and the continued immigration of new farmers and herders, what were the evolutions of the territories and the power relations between, on the one hand, indigenous and non-natural users of natural resources, and, on the other hand, biodiversity conservation agents? The land issues revealed by the zoning of the national park in the context of exponential population growth lead to new alliances, notably with the previously marginalized traditional authorities, which reaffirm their territorial rights in the process of nature patrimonialization. We show how the local strategies at work are in keeping with the old cultural model of each of these communities, centered on the territory and not on the biodiversity it contains. Discussions on the recognition of local practices and knowledge, as well as on the complementarity between emblematic and ordinary biodiversity, do not find any echoes in this area overwhelmed by uncontrolled immigration directly linked to the context of regional insecurity.
Keywords	Biodiversity ; Territory ; Nature conservancy ; Indigenous societies ; Participation ; Cameroon ; Geography (General) ; G1-922
Subject code	390
Language	English
Publishing date	2017-07-01T00:00:00Z
Publisher	Association AGF
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Giant epidermoid cyst of the occipital area with bone invasion: A case report.

Alorini, Mohammed / Vianney, Gilard / Florent, Marguet / Olivier, Langlois / Annie, Laquerrière

International journal of health sciences

2018 Volume 12, Issue 4, Page(s) 92–93

Abstract: Epidermoid cysts are slowly growing pseudotumors usually measuring <2 cm in diameter. Large epidermoid cysts invading bones have been rarely reported in the literature. They may be a source of diagnostic difficulties before pathological analyses, and ... ...

Abstract	Epidermoid cysts are slowly growing pseudotumors usually measuring <2 cm in diameter. Large epidermoid cysts invading bones have been rarely reported in the literature. They may be a source of diagnostic difficulties before pathological analyses, and radiological examinations are essential to determine the extension of the cyst and to guide the surgical technique. We report, herein, on a patient having an unusually large epidermoid cyst located in the left occipital area invading the occipital bone.
Language	English
Publishing date	2018-07-11
Publishing country	Saudi Arabia
Document type	Journal Article
ZDB-ID	2603595-9
ISSN	1658-3639
ISSN	1658-3639
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Targeting the Urotensin II/UT G Protein-Coupled Receptor to Counteract Angiogenesis and Mesenchymal Hypoxia/Necrosis in Glioblastoma

Vadim Le Joncour / Pierre-Olivier Guichet / Kleouforo-Paul Dembélé / Alexandre Mutel / Daniele Campisi / Nicolas Perzo / Laurence Desrues / Romain Modzelewski / Pierre-Olivier Couraud / Jérôme Honnorat / François-Xavier Ferracci / Florent Marguet / Annie Laquerrière / Pierre Vera / Pierre Bohn / Olivier Langlois / Fabrice Morin / Pierrick Gandolfo / Hélène Castel

Frontiers in Cell and Developmental Biology, Vol

2021 Volume 9

Abstract: Glioblastomas (GBMs) are the most common primary brain tumors characterized by strong invasiveness and angiogenesis. GBM cells and microenvironment secrete angiogenic factors and also express chemoattractant G protein-coupled receptors (GPCRs) to their ... ...

Abstract	Glioblastomas (GBMs) are the most common primary brain tumors characterized by strong invasiveness and angiogenesis. GBM cells and microenvironment secrete angiogenic factors and also express chemoattractant G protein-coupled receptors (GPCRs) to their advantage. We investigated the role of the vasoactive peptide urotensin II (UII) and its receptor UT on GBM angiogenesis and tested potential ligand/therapeutic options based on this system. On glioma patient samples, the expression of UII and UT increased with the grade with marked expression in the vascular and peri-necrotic mesenchymal hypoxic areas being correlated with vascular density. In vitro human UII stimulated human endothelial HUV-EC-C and hCMEC/D3 cell motility and tubulogenesis. In mouse-transplanted Matrigel sponges, mouse (mUII) and human UII markedly stimulated invasion by macrophages, endothelial, and smooth muscle cells. In U87 GBM xenografts expressing UII and UT in the glial and vascular compartments, UII accelerated tumor development, favored hypoxia and necrosis associated with increased proliferation (Ki67), and induced metalloproteinase (MMP)-2 and -9 expression in Nude mice. UII also promoted a “tortuous” vascular collagen-IV expressing network and integrin expression mainly in the vascular compartment. GBM angiogenesis and integrin αvβ3 were confirmed by in vivo99mTc-RGD tracer imaging and tumoral capture in the non-necrotic area of U87 xenografts in Nude mice. Peptide analogs of UII and UT antagonist were also tested as potential tumor repressor. Urotensin II-related peptide URP inhibited angiogenesis in vitro and failed to attract vascular and inflammatory components in Matrigel in vivo. Interestingly, the UT antagonist/biased ligand urantide and the non-peptide UT antagonist palosuran prevented UII-induced tubulogenesis in vitro and significantly delayed tumor growth in vivo. Urantide drastically prevented endogenous and UII-induced GBM angiogenesis, MMP, and integrin activations, associated with GBM tumoral growth. These findings ...
Keywords	glioblastoma ; urotensin II ; UT receptor ; angiogenesis ; necrosis ; biased ligand ; Biology (General) ; QH301-705.5
Subject code	610
Language	English
Publishing date	2021-04-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Correction

Ahmed Idbaih / François Ducray / Caroline Dehais / Célia Courdy / Catherine Carpentier / Simon de Bernard / Emmanuelle Uro-Coste / Karima Mokhtari / Anne Jouvet / Jérôme Honnorat / Olivier Chinot / Carole Ramirez / Patrick Beauchesne / Alexandra Benouaich-Amiel / Joël Godard / Sandrine Eimer / Fabrice Parker / Emmanuelle Lechapt-Zalcman / Philippe Colin /

PLoS ONE, Vol 8, Iss

SNP Array Analysis Reveals Novel Genomic Abnormalities Including Copy Neutral Loss of Heterozygosity in Anaplastic Oligodendrogliomas.

2013 Volume 5

Keywords	Medicine ; R ; Science ; Q
Language	English
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Correction

PLoS ONE, Vol 8, Iss

SNP Array Analysis Reveals Novel Genomic Abnormalities Including Copy Neutral Loss of Heterozygosity in Anaplastic Oligodendrogliomas

2013 Volume 5

Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2013-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: SNP array analysis reveals novel genomic abnormalities including copy neutral loss of heterozygosity in anaplastic oligodendrogliomas.

PLoS ONE, Vol 7, Iss 10, p e

2012 Volume 45950

Abstract: Anaplastic oligodendrogliomas (AOD) are rare glial tumors in adults with relative homogeneous clinical, radiological and histological features at the time of diagnosis but dramatically various clinical courses. Studies have identified several molecular ... ...

Abstract	Anaplastic oligodendrogliomas (AOD) are rare glial tumors in adults with relative homogeneous clinical, radiological and histological features at the time of diagnosis but dramatically various clinical courses. Studies have identified several molecular abnormalities with clinical or biological relevance to AOD (e.g. t(1;19)(q10;p10), IDH1, IDH2, CIC and FUBP1 mutations).To better characterize the clinical and biological behavior of this tumor type, the creation of a national multicentric network, named "Prise en charge des OLigodendrogliomes Anaplasiques (POLA)," has been supported by the Institut National du Cancer (InCA). Newly diagnosed and centrally validated AOD patients and their related biological material (tumor and blood samples) were prospectively included in the POLA clinical database and tissue bank, respectively.At the molecular level, we have conducted a high-resolution single nucleotide polymorphism array analysis, which included 83 patients. Despite a careful central pathological review, AOD have been found to exhibit heterogeneous genomic features. A total of 82% of the tumors exhibited a 1p/19q-co-deletion, while 18% harbor a distinct chromosome pattern. Novel focal abnormalities, including homozygously deleted, amplified and disrupted regions, have been identified. Recurring copy neutral losses of heterozygosity (CNLOH) inducing the modulation of gene expression have also been discovered. CNLOH in the CDKN2A locus was associated with protein silencing in 1/3 of the cases. In addition, FUBP1 homozygous deletion was detected in one case suggesting a putative tumor suppressor role of FUBP1 in AOD.Our study showed that the genomic and pathological analyses of AOD are synergistic in detecting relevant clinical and biological subgroups of AOD.
Keywords	Medicine ; R ; Science ; Q
Subject code	610
Language	English
Publishing date	2012-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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