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Article ; Online: Endoscopic Endonasal Approach for Resection of a Recurrent Craniopharyngioma: Techniques to Maximize Surgical Exposure and Extent of Resection.

Almeida, Joao Paulo / Marenco-Hillembrand, Lina / Moniz-Garcia, Diogo / Goyal, Anshit / Olomu, Osarenoma U / Quinones-Hinojosa, Alfredo

World neurosurgery

2023 Volume 180, Page(s) 66

Abstract: Craniopharyngiomas are challenging tumors of the central nervous system that originate from epithelial remnants of the Rathke pouch. ...

Abstract	Craniopharyngiomas are challenging tumors of the central nervous system that originate from epithelial remnants of the Rathke pouch.
MeSH term(s)	Male ; Humans ; Middle Aged ; Craniopharyngioma/diagnostic imaging ; Craniopharyngioma/surgery ; Neuroendoscopy/methods ; Treatment Outcome ; Pituitary Neoplasms/diagnostic imaging ; Pituitary Neoplasms/surgery ; Neoplasm Recurrence, Local/surgery ; Brain Neoplasms/surgery
Language	English
Publishing date	2023-07-15
Publishing country	United States
Document type	Case Reports ; Video-Audio Media
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2023.07.031
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Article ; Conference proceedings: Endoscopic Endonasal Approach: Recurrent Fibrous Pituitary Adenoma with Cavernous Sinus Extension

Almeida, Joao P. / Perez-Vega, Carlos / Samson, Susan L. / Olomu, Osarenoma U. / Quinones-Hinojosa, Alfredo

Journal of Neurological Surgery Part B: Skull Base

2023 Volume 84, Issue S 01

Event/congress	32nd Annual Meeting North American Skull Base Society, JW Marriott Tampa Water Street, Tampa, Florida, United States, 2023-02-17
Language	English
Publishing date	2023-02-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0043-1762525
Database	Thieme publisher's database

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Zs.A 3425: Show issues

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Article ; Conference proceedings: Expanded Endoscopic Endonasal Approach for Resection of a Recurrent Craniopharyngioma

Almeida, Joao Paulo / Marenco-Hillembrand, Lina / Moniz-Garcia, Diogo / Goyal, Anshit / Olomu, Osarenoma U. / Quinones-Hinojosa, Alfredo

Journal of Neurological Surgery Part B: Skull Base

2023 Volume 84, Issue S 01

Event/congress	32nd Annual Meeting North American Skull Base Society, JW Marriott Tampa Water Street, Tampa, Florida, United States, 2023-02-17
Language	English
Publishing date	2023-02-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0043-1762506
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Article: Can Diffusion-Weighted Imaging Serve as an Imaging Biomarker for Acute Bacterial Rhinosinusitis?

Bhatt, Alok A / Donaldson, Angela M / Olomu, Osarenoma U / Gupta, Vivek / Sandhu, Sukhwinder Johnny S

Cureus

2020 Volume 12, Issue 8, Page(s) e9893

Abstract: Acute rhinosinusitis is defined as symptomatic inflammation of the mucosal lining of the nasal cavity and paranasal sinuses lasting less than four weeks. It is most commonly secondary to viral infection but is often challenging to distinguish from ... ...

Abstract	Acute rhinosinusitis is defined as symptomatic inflammation of the mucosal lining of the nasal cavity and paranasal sinuses lasting less than four weeks. It is most commonly secondary to viral infection but is often challenging to distinguish from bacterial etiologies. Even with recommendations from several specialty societies, there continues to be a frequent practice of overprescribing oral antibiotics for acute rhinosinusitis, thus leading to multidrug-resistant organisms, and rendering oral medication useless when actually clinically warranted. We observed a potential non-invasive imaging biomarker that could predict which patients would benefit from anti-microbial therapy. Often computed tomography (CT) imaging is obtained by the provider before consultation with the otolaryngologist, sometimes leading to unnecessary radiation to the patient. In addition, there are no clear CT findings to make the diagnosis of acute rhinosinusitis. The diagnosis is challenging for all clinicians involved, and therefore, additional signs on other imaging modalities would be helpful. We present a series of four patients with incidentally discovered culture-positive acute rhinosinusitis. Patients with incidentally discovered culture-positive acute rhinosinusitis were found to also have magnetic resonance imaging (MRI) that showed corresponding restricted diffusion on diffusion-weighted imaging (DWI). An imaging biomarker for acute bacterial rhinosinusitis may improve the appropriate use of antibiotic therapy. DWI MRI should be further investigated as a potential candidate screening modality.
Language	English
Publishing date	2020-08-20
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.9893
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Article: Machine Learning Models to Forecast Outcomes of Pituitary Surgery: A Systematic Review in Quality of Reporting and Current Evidence.

Rech, Matheus M / de Macedo Filho, Leonardo / White, Alexandra J / Perez-Vega, Carlos / Samson, Susan L / Chaichana, Kaisorn L / Olomu, Osarenoma U / Quinones-Hinojosa, Alfredo / Almeida, Joao Paulo

Brain sciences

2023 Volume 13, Issue 3

Abstract: Background: The complex nature and heterogeneity involving pituitary surgery results have increased interest in machine learning (ML) applications for prediction of outcomes over the last decade. This study aims to systematically review the ... ...

Abstract	Background: The complex nature and heterogeneity involving pituitary surgery results have increased interest in machine learning (ML) applications for prediction of outcomes over the last decade. This study aims to systematically review the characteristics of ML models involving pituitary surgery outcome prediction and assess their reporting quality. Methods: We searched the PubMed, Scopus, and Web of Knowledge databases for publications on the use of ML to predict pituitary surgery outcomes. We used the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) to assess report quality. Our search strategy was based on the terms "artificial intelligence", "machine learning", and "pituitary". Results: 20 studies were included in this review. The principal models reported in each article were post-surgical endocrine outcomes ( Conclusion: Applications of ML in the prediction of pituitary outcomes are still nascent, as evidenced by the lack of any model validated for clinical practice. Although studies have demonstrated promising results, greater transparency in model development and reporting is needed to enable their use in clinical practice. Further adherence to reporting guidelines can help increase AI's real-world utility and improve clinical practice.
Language	English
Publishing date	2023-03-15
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2651993-8
ISSN	2076-3425
ISSN	2076-3425
DOI	10.3390/brainsci13030495
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Article ; Conference proceedings: Twenty-Four-Hour Discharge following Transsphenoidal Resection of Pituitary Adenomas: Safety and Feasibility of a Pituitary-Center Cohort

Perez-Vega, Carlos / Sanchez-Garavito, J. Emiliano / Ravindran, Krishnan / Donaldson, Angela M. / Olomu, Osarenoma U. / Chaichana, Kaisorn L. / Quinones-Hinojosa, Alfredo / Samson, Susan L. / Almeida, Joao P.

Journal of Neurological Surgery Part B: Skull Base

2024 Volume 85, Issue S 01

Event/congress	33rd Annual Meeting North American Skull Base Society, Atlanta Marriott Marquis Atlanta, Georgia, United States, 2024-02-16
Language	English
Publishing date	2024-02-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0044-1779974
Database	Thieme publisher's database

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Article ; Online: Smell Outcomes in Olfactory Groove Meningioma Resection Through Unilateral versus Bilateral Transcranial Approaches: A Systematic Review and Meta-analysis.

Bamimore, Michael A / Marenco-Hillembrand, Lina / Ravindran, Krishnan / Perdikis, Blake / Rosado-Philippi, Julio / Jeevaratnam, Suren / Donaldson, Angela M / Olomu, Osarenoma U / Chaichana, Kaisorn L

World neurosurgery

2022 Volume 160, Page(s) 22–32

Abstract: Objective: Olfactory disturbance is a common complication that occurs following the surgical resection of olfactory groove meningiomas (OGMs). There is little evidence on the best transcranial approach that minimizes rates of postoperative olfactory ... ...

Abstract	Objective: Olfactory disturbance is a common complication that occurs following the surgical resection of olfactory groove meningiomas (OGMs). There is little evidence on the best transcranial approach that minimizes rates of postoperative olfactory disturbance. The objective of this systematic review and meta-analysis is to compare smell outcomes after OGM resection in unilateral versus bilateral transcranial approaches. Methods: A systematic review of the literature and meta-analysis was conducted using PUBMED, SCOPUS, and EMBASE in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The primary endpoint was incidence of new olfactory disturbance defined as anosmia or hyposmia, or both. Patients were classified as undergoing either a unilateral or bilateral approach. Data on presence of new postoperative olfactory deficits were used to generate standardized mean differences and 95% confidence intervals. Results: Ten studies met the inclusion criteria for quantitative analysis, comprising 342 patients. A total of 216 patients underwent unilateral approaches while 126 underwent resection via bilateral approach. In the unilateral approach cohort, 17.1% experienced new postoperative olfactory disturbance following resection, compared with 19.2% of patients in the bilateral approach cohort. Forest plot did not reveal any significant difference in the incidence of new olfactory disturbance following either unilateral or bilateral approaches. Conclusions: Our data suggest that there is no significant difference between the investigated transcranial approaches and postoperative olfactory disturbances. Accordingly, our study suggests that further investigation with introduced experimental control could provide more insight into the capabilities and drawbacks of each route in relation to olfactory outcomes.
MeSH term(s)	Craniotomy ; Humans ; Meningeal Neoplasms/surgery ; Meningioma/surgery ; Neurosurgical Procedures/adverse effects ; Smell ; Treatment Outcome
Language	English
Publishing date	2022-01-13
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Review ; Systematic Review
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2022.01.034
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Article ; Online: Spontaneous Cerebrospinal Fluid Leak Presenting as Chronic Rhinitis.

Marenco-Hillembrand, Lina / Alvarez-Elcoro, Salvador / Olomu, Osarenoma U / Quinones-Hinojosa, Alfredo / Gupta, Vivek / Gonzalez-Estrada, Alexei

The journal of allergy and clinical immunology. In practice

2019 Volume 8, Issue 2, Page(s) 734–735

MeSH term(s)	Cerebrospinal Fluid Leak/diagnosis ; Humans ; Rhinitis/diagnosis
Language	English
Publishing date	2019-10-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2843237-X
ISSN	2213-2201 ; 2213-2198
ISSN (online)	2213-2201
ISSN	2213-2198
DOI	10.1016/j.jaip.2019.09.019
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Article ; Online: Endoscopic endonasal transclival approach to the ventral brainstem: Radiologic, anatomic feasibility and nuances, surgical limitations and future directions.

Karadag, Ali / Senoglu, Mehmet / Middlebrooks, Erik H / Kinali, Burak / Guvencer, Mustafa / Icke, Cigdem / Sayhan, Salih / Karabay, Nuri / Camlar, Mahmut / Olomu, Osarenoma U / Tanriover, Necmettin

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

2020 Volume 73, Page(s) 264–279

Abstract: The endoscopic endonasal transclival approach (EETA) is less invasive than traditional open approaches; however, there is currently limited data on the pre-operative features that may predict success of the EETA. Surgical landmarks and exposure of the ... ...

Abstract	The endoscopic endonasal transclival approach (EETA) is less invasive than traditional open approaches; however, there is currently limited data on the pre-operative features that may predict success of the EETA. Surgical landmarks and exposure of the EETA and expanded EETA are assessed. We retrospectively measured multiple anatomic features in 154 adult dry skulls, 22 C1 and C2 dry bone vertebrae, and 500 paranasal sinus computed tomography (CT) scans. We also dissected 13 formalin-fixed, silicone-injected adult cadaveric heads. Relevant qualitative and quantitative data were obtained with CT (n = 10) and cadaveric dissection (n = 13). They are expressed as mean (SD), as appropriate and compared with unpaired t tests. Categorical variables were compared with χ
MeSH term(s)	Adult ; Brain Stem/diagnostic imaging ; Brain Stem/surgery ; Cranial Fossa, Posterior/diagnostic imaging ; Cranial Fossa, Posterior/surgery ; Humans ; Natural Orifice Endoscopic Surgery/methods ; Nose ; Sphenoid Sinus/diagnostic imaging ; Sphenoid Sinus/surgery
Language	English
Publishing date	2020-01-28
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	1193674-5
ISSN	1532-2653 ; 0967-5868
ISSN (online)	1532-2653
ISSN	0967-5868
DOI	10.1016/j.jocn.2020.01.012
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Article ; Online: Vestibular perception and the vestibulo-ocular reflex in young and older adults.

Chang, Nai-Yuan Nicholas / Hiss, Meghan M / Sanders, Mark C / Olomu, Osarenoma U / MacNeilage, Paul R / Uchanski, Rosalie M / Hullar, Timothy E

Ear and hearing

2014 Volume 35, Issue 5, Page(s) 565–570

Abstract: Objectives: Quantification of the perceptual thresholds to vestibular stimuli may offer valuable complementary information to that provided by measures of the vestibulo-ocular reflex (VOR). Perceptual thresholds could be particularly important in ... ...

Abstract	Objectives: Quantification of the perceptual thresholds to vestibular stimuli may offer valuable complementary information to that provided by measures of the vestibulo-ocular reflex (VOR). Perceptual thresholds could be particularly important in evaluating some subjects, such as the elderly, who might have a greater potential of central as well as peripheral vestibular dysfunction. The authors hypothesized that perceptual detection and discrimination thresholds would worsen with aging, and that there would be a poor relation between thresholds and traditional measures of the angular VOR represented by gain and phase on rotational chair testing. Design: The authors compared the detection and discrimination thresholds of 19 younger and 16 older adults in response to earth-vertical, 0.5 Hz rotations. Perceptual results of the older subjects were then compared with the gain and phase of their VOR in response to earth-vertical rotations over the frequency range from 0.025 to 0.5 Hz. Results: Detection thresholds were found to be 0.69 ± 0.29 degree/sec (mean ± standard deviation) for the younger participants and 0.81 ± 0.42 degree/sec for older participants. Discrimination thresholds in younger and older adults were 4.83 ± 1.80 degree/sec and 4.33 ± 1.57 degree/sec, respectively. There was no difference in either measure between age groups. Perceptual thresholds were independent of the gain and phase of the VOR. Conclusions: These results indicate that there is no inevitable loss of vestibular perception with aging. Elevated thresholds among the elderly are therefore suggestive of pathology rather than normal consequences of aging. Furthermore, perceptual thresholds offer additional insight, beyond that supplied by the VOR alone, into vestibular function.
MeSH term(s)	Adult ; Age Factors ; Aged ; Aged, 80 and over ; Differential Threshold ; Female ; Humans ; Male ; Middle Aged ; Reflex, Vestibulo-Ocular/physiology ; Rotation ; Sensory Thresholds/physiology ; Vestibular Diseases/physiopathology ; Young Adult
Language	English
Publishing date	2014-08-21
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	603093-2
ISSN	1538-4667 ; 0196-0202
ISSN (online)	1538-4667
ISSN	0196-0202
DOI	10.1097/AUD.0000000000000052
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