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Article: Experimental analysis of ON/OFF and variable speed drive controlled industrial chiller towards energy efficient operation

Olszewski, Pawel

Applied energy. 2022 Mar. 01, v. 309

2022

Abstract: This study demonstrates thermodynamic and energy effects of a Variable Speed Drive (VSD), powering compressor in a partially loaded chiller system. The proposed work fits the gap in the existing literature, which mostly addresses VSD applications in ... ...

Abstract	This study demonstrates thermodynamic and energy effects of a Variable Speed Drive (VSD), powering compressor in a partially loaded chiller system. The proposed work fits the gap in the existing literature, which mostly addresses VSD applications in chiller’s auxiliary pumps and fans. The goals of this work are defined by four Research Problems (RP’s): RP1. comparison of thermodynamic extensive parameters, for ON/OFF and VSD controlled systems, RP2. load ranges in which VSD control systems are energy efficient, RP 3. potential energy savings in VSD controlled compressor, and RP 4. mathematical model formulation, useful in energy audit conditions, estimating potential benefits of VSD implementation, based on measurement data from existing ON-OFF controlled chiller. To address these aspects, a set of measurements have been performed on a fully equipped experimental chiller system (UW Oshkosh Teaching and Energy Research Industrial Lab). All data have been collected for a wide spectrum of loads in both control configurations. Data analysis showed significant differences in a chiller operation. VSD operated chiller eliminates fluctuations in all measured thermodynamic parameters (RP1.). The accomplished work demonstrated that the most energy efficient effects can be achieved for a partially loaded, VSD-controlled chiller, working at ∼55–75% of its nominal capacity (RP 2.). The implementation of a Variable Speed Drive for such load levels allows for achieving up to 25% of energy savings (RP 3.) Finally, proposed mathematical model have been experimentally verified as useful in the range of 50–100% of nominal load (RP 4.).
Keywords	energy efficiency ; mathematical models ; potential energy
Language	English
Dates of publication	2022-0301
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	2000772-3
ISSN	0306-2619
ISSN	0306-2619
DOI	10.1016/j.apenergy.2021.118440
Database	NAL-Catalogue (AGRICOLA)

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Article: Respecting the Patient's Right to Information in Hospital Wards in Poland - Socio-Economic Determinants of Patients' Opinions.

Borowska, Mariola / Augustynowicz, Anna / Olszewski, Paweł / Religioni, Urszula

Patient preference and adherence

2023 Volume 17, Page(s) 2311–2323

Abstract: Background: Implementation of the patient's statutory right to information is one of determinants the quality and safety of medical services. The patients' opinions survey is an element of patient-centric care, which is now one of the most important ... ...

Abstract	Background: Implementation of the patient's statutory right to information is one of determinants the quality and safety of medical services. The patients' opinions survey is an element of patient-centric care, which is now one of the most important things in modern healthcare. The main aim of the work is to examine patients' opinions on the observance of patients' right to information in the hospital and quality of healthcare in the hospital. A secondary objective was to examine the impact of socioeconomic variables on patients' opinions. Materials and methods: The study was based on the Computer-Assisted Web Interview (CAWI) questionnaire, carried out in March 2022. The sample included 801 persons. Respondents were patients hospitalized within a maximum of 12 months. The questionnaire contained closed questions about the quality of medical care, observance of the patient's right to information. Results: Probability of referral was measured using the Net Promoter Score (NPS). Respondents answered the question about the recommendation on a scale from 0 to 10. People who rated the hospital ward at 10 and 9 are promoters, people who rated the hospital ward at 8 and 7 are neutral people. In turn, people who rated the hospital ward at 6, 5, 4, 3, 2, 1 or 0 are critics, ie people who will not recommend the hospital to their relatives. Most patients in hospital wards were the detractors (37%). The percentage of promoters was only 1% lower (36%) than that of the detractors. Patients was rated medical and nursing staff at a similar level with regard to the observance of the patient's right to information. Conclusion: Most statistically significant differences in the assessment of medical care in the hospital ward were associated with such sociodemographic variables as age and income. People aged 55-64 and 65+ rated most of the analyzed aspects better.
Language	English
Publishing date	2023-09-18
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2455848-5
ISSN	1177-889X
ISSN	1177-889X
DOI	10.2147/PPA.S421336
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Article ; Online: Analyzing the dynamics of meningococcal vaccinations initiatives by local government units in Poland (2017-2021) - Scope, challenges and recommendations.

Świtalski, Jakub / Miazga, Wojciech / Wnuk, Katarzyna / Tatara, Tomasz / Olszewski, Paweł / Jankowski, Mateusz / Augustynowicz, Anna

Vaccine

2024

Abstract: Introduction: Meningococcal vaccinations are recommended by Polish public health authorities but lack coverage under health insurance, prompting Local Government Units (LGUs) to implement local health policy programs. This study examines the ... ...

Abstract	Introduction: Meningococcal vaccinations are recommended by Polish public health authorities but lack coverage under health insurance, prompting Local Government Units (LGUs) to implement local health policy programs. This study examines the effectiveness and impact of LGU-driven meningococcal vaccination initiatives in Poland between 2017 and 2021. Material and methods: A retrospective analysis utilized data from reports on local public health interventions submitted annually to the Ministry of Health in Poland. The study focused on the number of meningococcal vaccination programs, their scope, the vaccinated population, and associated program costs. Additionally, nationwide data on meningococcal disease incidence and vaccine uptake were analyzed. Results: Within LGUs programs, 48,617 individuals received meningococcal vaccinations, constituting approximately 10% of all vaccinations in Poland during the study period. Notably, cities with poviat rights spearheaded programs covering 54% of the total participants. The total cost incurred by these initiatives amounted to EUR 2,553,661. Conclusions: While LGUs activities positively contributed to increased meningococcal vaccination rates, the overall engagement of local governments remains limited. The findings underscore the importance of expanding local government involvement in meningococcal vaccination programs to address public health needs effectively. Improved collaboration and increased funding may enhance the reach and impact of these initiatives.
Language	English
Publishing date	2024-04-22
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2024.04.046
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Article ; Online: Comparative Analysis of Symptomatology in Hospitalized Children with RSV, COVID-19, and Influenza Infections.

Balas, Weronika M / Śliwczyński, Andrzej / Olszewski, Paweł / Gołębiak, Izabela / Sybilski, Adam J

Medical science monitor : international medical journal of experimental and clinical research

2023 Volume 29, Page(s) e941229

Abstract: BACKGROUND The clinical course of respiratory syncytial virus (RSV), SARS-CoV-2, and influenza infections comprises many non-specific symptoms, which makes diagnosis difficult. The aim of this study was to retrospectively analyze the symptomatology of ... ...

Abstract	BACKGROUND The clinical course of respiratory syncytial virus (RSV), SARS-CoV-2, and influenza infections comprises many non-specific symptoms, which makes diagnosis difficult. The aim of this study was to retrospectively analyze the symptomatology of these infections in children and to search for correlations between them. MATERIAL AND METHODS A total of 121 children with a positive RSV (n=61), influenza (n=31), or SARS-CoV-2 (n=29) antigen test were enrolled in this retrospective analysis. Children were aged up to 71 months (median, 8 months). The collected data were collated by performing statistical analysis using the chi-square test and comparing the results using OR (odds ratio) and 95%CI (confidence interval). RESULTS There was a higher risk of fever in children with influenza than in those with RSV. Patients infected with RSV had a higher risk of nasal blockage than those with SARS-CoV-2. Dyspnea was more common in RSV infection than in influenza. Severe, sleep-awakening cough was more frequent in children with RSV than in those with COVID-19. Influenza was more prevalent in children aged >24 months than in those aged 7-24 months. RSV-infected children had a higher risk of numerous auscultatory changes compared to those with SARS-CoV-2. In the case of RSV infection, symptoms requiring hospitalization occurred later than in SARS-CoV-2 infection. CONCLUSIONS Children aged >24 months were at higher risk of contracting influenza. Numerous auscultatory changes, nasal blockage, and dyspnea were more common in children with RSV. There was a higher risk of dyspnea in children with RSV. Fever was more frequent in children with influenza. However, none of the symptoms clearly indicated the etiology of the infection.
MeSH term(s)	Child ; Humans ; Influenza, Human/diagnosis ; Retrospective Studies ; Child, Hospitalized ; Nasal Obstruction ; COVID-19/complications ; SARS-CoV-2 ; Respiratory Syncytial Virus, Human ; Respiratory Syncytial Virus Infections/complications ; Fever ; Dyspnea ; Respiratory Tract Infections
Language	English
Publishing date	2023-11-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	1439041-3
ISSN	1643-3750 ; 1234-1010
ISSN (online)	1643-3750
ISSN	1234-1010
DOI	10.12659/MSM.941229
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ab Jg. 2022: Lesesaal (EG)

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Article: The Usage of Cryopreserved Reproductive Material in Cancer Patients Undergoing Fertility Preservation Procedures.

Wnuk, Katarzyna / Świtalski, Jakub / Miazga, Wojciech / Tatara, Tomasz / Religioni, Urszula / Olszewski, Paweł / Augustynowicz, Anna

Cancers

2023 Volume 15, Issue 22

Abstract: Background: Many cancer treatment methods can affect fertility by damaging the reproductive organs and glands that control fertility. Changes can be temporary or permanent. In order to preserve the fertility of cancer patients and protect the genital ... ...

Abstract	Background: Many cancer treatment methods can affect fertility by damaging the reproductive organs and glands that control fertility. Changes can be temporary or permanent. In order to preserve the fertility of cancer patients and protect the genital organs against gonadotoxicity, methods of fertility preservation are increasingly used. Considering that some patients ultimately decide not to use cryopreserved reproductive material, this review analysed the percentage of post-cancer patients using cryopreserved reproductive material, collected before treatment as part of fertility preservation. Methods: A systematic search of studies was carried out in accordance with the Cochrane Collaboration guidelines, based on a previously prepared research protocol. The search was conducted in Medline (via PubMed), Embase (via OVID), and the Cochrane Library. In addition, a manual search was performed for recommendations/clinical practice guidelines regarding fertility preservation in cancer patients. Results: Twenty-six studies met the inclusion criteria. The studies included in the review discussed the results of cryopreservation of oocytes, embryos, ovarian tissue, and semen. In 10 studies, the usage rate of cryopreserved semen ranged from 2.6% to 21.5%. In the case of cryopreserved female reproductive material, the return/usage rate ranged from 3.1% to 8.7% for oocytes, approx. 9% to 22.4% for embryos, and 6.9% to 30.3% for ovarian tissue. In studies analysing patients' decisions about unused reproductive material, continuation of material storage was most often indicated. Recovering fertility or death of the patient were the main reasons for rejecting cryopreserved semen in the case of men. Conclusion: Fertility preservation before gonadotoxic treatment is widely recommended and increasingly used in cancer patients. The usage rate is an important indicator for monitoring the efficacy of these methods. In all of the methods described in the literature, this indicator did not exceed 31%. It is necessary to create legal and organizational solutions regulating material collection and storage and to create clear paths for its usage in the future, including by other recipients.
Language	English
Publishing date	2023-11-09
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers15225348
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Article ; Online: Behavioral plasticity: Role of neuropeptides in shaping feeding responses.

Levine, Allen S / Jewett, David C / Kotz, Catherine M / Olszewski, Pawel K

Appetite

2022 Volume 174, Page(s) 106031

Abstract: Behavioral plasticity refers to changes occurring due to external influences on an organism, including adaptation, learning, memory and enduring influences from early life experience. There are 2 types of behavioral plasticity: "developmental", which ... ...

Abstract	Behavioral plasticity refers to changes occurring due to external influences on an organism, including adaptation, learning, memory and enduring influences from early life experience. There are 2 types of behavioral plasticity: "developmental", which refers to gene/environment interactions affecting a phenotype, and "activational" which refers to innate physiology and can involve structural physiological changes of the body. In this review, we focus on feeding behavior, and studies involving neuropeptides that influence behavioral plasticity - primarily opioids, orexin, neuropeptide Y, and oxytocin. In each section of the review, we include examples of behavioral plasticity as it relates to actions of these neuropeptides. It can be concluded from this review that eating behavior is influenced by a number of external factors, including time of day, type of food available, energy balance state, and stressors. The reviewed work underscores that environmental factors play a critical role in feeding behavior and energy balance, but changes in eating behavior also result from a multitude of non-environmental factors, such that there can be no single mechanism or variable that can explain ingestive behavior.
MeSH term(s)	Feeding Behavior/physiology ; Humans ; Neuropeptide Y/genetics ; Neuropeptides ; Oxytocin
Chemical Substances	Neuropeptide Y ; Neuropeptides ; Oxytocin (50-56-6)
Language	English
Publishing date	2022-04-06
Publishing country	England
Document type	Journal Article ; Review ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1461347-5
ISSN	1095-8304 ; 0195-6663
ISSN (online)	1095-8304
ISSN	0195-6663
DOI	10.1016/j.appet.2022.106031
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Article: Ash from Poultry Manure Incineration as a Substitute for Phosphorus Fertiliser.

Cempa, Magdalena / Olszewski, Paweł / Wierzchowski, Krzysztof / Kucharski, Piotr / Białecka, Barbara

Materials (Basel, Switzerland)

2022 Volume 15, Issue 9

Abstract: The goal of the tests was to separate a phosphate concentrate from ash and to assess its fertiliser use efficiency in anthropogenic land. Ash obtained from poultry manure incineration is an interesting fertiliser, as it contains both of the necessary ... ...

Abstract	The goal of the tests was to separate a phosphate concentrate from ash and to assess its fertiliser use efficiency in anthropogenic land. Ash obtained from poultry manure incineration is an interesting fertiliser, as it contains both of the necessary nutrients, i.e., phosphorus and potassium. The ash selected for the tests contained 15.73 wt% P
Language	English
Publishing date	2022-04-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma15093023
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Article: Genetic optimization and experimental verification of complex parallel pumping station with centrifugal pumps

Olszewski, Pawel

Applied energy. 2016 Sept. 15, v. 178

2016

Abstract: While single pump design allows operation at high performance levels, multi-pumping systems are controlled to cover actual flow rate requirements, with less emphasis on power consumption. Widely accessible sensors and programmable controllers can improve ...

Abstract	While single pump design allows operation at high performance levels, multi-pumping systems are controlled to cover actual flow rate requirements, with less emphasis on power consumption. Widely accessible sensors and programmable controllers can improve this approach.This paper discusses the methodology for optimizing analysis of a complex pumping system with set of parallel centrifugal pumps. For this purpose, an experimental model pumping station, with four pumps in a parallel configuration, was designed and constructed. Auxiliary equipment allows control of each pump by three possible methods: (i) discharge valve, (ii) by-pass flow, and (iii) variable speed drive (VSD). For system performance optimization, three estimating strategies, that are functions of control input parameters at each pump were proposed: (i) minimization of power consumption, (ii) flow rate balancing and (iii) maximization of overall efficiency.A Uniquely developed (C++) genetic algorithm (GENOCOP) determined solutions and these were positively verified by measurements at the model experimental station. Results show the existence of multiple local extrema for all of estimating strategies. These solutions show it is possible to control a complex pumping station with various combinations of control parameters, giving similar results. This analysis demonstrates that the strategy of minimizing power consumption is the most energy efficient and proves the described methodology as a powerful tool for optimizing of complex pumping stations.
Keywords	algorithms ; centrifugal pumps ; computer software ; controllers ; energy efficiency ; energy use and consumption ; models
Language	English
Dates of publication	2016-0915
Size	p. 527-539.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	2000772-3
ISSN	0306-2619
ISSN	0306-2619
DOI	10.1016/j.apenergy.2016.06.084
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Article ; Online: TECS: a toxin expression control strategy as a tool for optimization of inducible promoters.

Małachowska, Aleksandra / Olszewski, Paweł

Microbial cell factories

2018 Volume 17, Issue 1, Page(s) 40

Abstract: Background: Transcriptional control of gene expression is a widely utilized regulatory mechanism in synthetic biology, biotechnology and recombinant protein production. It is achieved by utilization of naturally occurring promoters responding to ... ...

Abstract	Background: Transcriptional control of gene expression is a widely utilized regulatory mechanism in synthetic biology, biotechnology and recombinant protein production. It is achieved by utilization of naturally occurring promoters responding to nutrients or chemicals. Despite their regulatory properties, these promoters often possess features which diminish their utility for biotechnology. High basal expression level and low induction ratio can be removed using genetic engineering techniques, although this process is often laborious and time-consuming. Results: In order to facilitate optimization process for inducible promoters, we developed a simple method based on a conditional toxin expression which we abbreviate as toxin expression control strategy (TECS). In the presence of sucrose, SacB enzyme from Bacillus subtilis synthesizes levans which cause Eschericha coli cell lysis. However, in the absence of sucrose the enzyme does not affect the growth of the host. We utilized this feature to develop a two-step protocol allowing for efficient selection of inducible promoter variants. Using TECS we were able to modify the well-described p Conclusions: We show that TECS is an efficient tool for optimization and development of inducible promoter systems in E. coli. Our strategy is very effective in the selection of promoter variants with improved properties. Its simplicity and short hands-on time make it an attractive method to optimize existing promoters and to construct novel, engineered genetic elements which improve properties of an inducible promoter system.
MeSH term(s)	Bacillus subtilis/enzymology ; Bacillus subtilis/genetics ; Bacterial Toxins/genetics ; Escherichia coli/genetics ; Gene Expression ; Genetic Engineering ; Microorganisms, Genetically-Modified ; Promoter Regions, Genetic ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Sucrose/pharmacology ; Synthetic Biology
Chemical Substances	Bacterial Toxins ; Recombinant Proteins ; Sucrose (57-50-1)
Language	English
Publishing date	2018-03-13
Publishing country	England
Document type	Journal Article
ISSN	1475-2859
ISSN (online)	1475-2859
DOI	10.1186/s12934-018-0891-1
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Article: Mild Hypophagia and Associated Changes in Feeding-Related Gene Expression and c-Fos Immunoreactivity in Adult Male Rats with Sodium Valproate-Induced Autism

Pal, Tapasya / Laloli, Kathryn J. / Moscrip, Cushla A. / Olszewski, Pawel K. / Klockars, Anica

Genes. 2022 Jan. 28, v. 13, no. 2

2022

Abstract: A core yet understudied symptom of autism is aberrant eating behaviour, including extremely narrow food preferences. Autistic individuals often refuse to eat despite hunger unless preferred food is given. We hypothesised that, apart from aberrant ... ...

Abstract	A core yet understudied symptom of autism is aberrant eating behaviour, including extremely narrow food preferences. Autistic individuals often refuse to eat despite hunger unless preferred food is given. We hypothesised that, apart from aberrant preference, underfeeding stems from abnormal hunger processing. Utilising an adult male VPA rat, a model of autism, we examined intake of ‘bland’ chow in animals maintained on this diet continuously, eating this food after fasting and after both food and water deprivation. We assessed body weight in adulthood to determine whether lower feeding led to slower growth. Since food intake is highly regulated by brain processes, we looked into the activation (c-Fos immunoreactivity) of central sites controlling appetite in animals subjected to food deprivation vs. fed ad libitum. Expression of genes involved in food intake in the hypothalamus and brain stem, regions responsible for energy balance, was measured in deprived vs. sated animals. We performed our analyses on VPAs and age-matched healthy controls. We found that VPAs ate less of the ‘bland’ chow when fed ad libitum and after deprivation than controls did. Their body weight increased more slowly than that of controls when maintained on the ‘bland’ food. While hungry controls had lower c-Fos IR in key feeding-related areas than their ad libitum-fed counterparts, in hungry VPAs c-Fos was unchanged or elevated compared to the fed ones. The lack of changes in expression of feeding-related genes upon deprivation in VPAs was in contrast to several transcripts affected by fasting in healthy controls. We conclude that hunger processing is dysregulated in the VPA rat.
Keywords	ad libitum feeding ; adulthood ; adults ; autism ; body weight ; brain stem ; energy balance ; food deprivation ; food intake ; gene expression ; hunger ; hypothalamus ; immune response ; males ; models ; rats ; sodium ; undereating ; water deprivation
Language	English
Dates of publication	2022-0128
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2527218-4
ISSN	2073-4425
ISSN	2073-4425
DOI	10.3390/genes13020259
Database	NAL-Catalogue (AGRICOLA)

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