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  1. Article ; Online: Prevalence of surgically correctable conditions among children in a mixed urban-rural community in Nigeria using the SOSAS survey tool

    Adesoji O Ademuyiwa / Tinuola O Odugbemi / Christopher O Bode / Olumide A Elebute / Felix M Alakaloko / Eyitayo O Alabi / Olufemi Bankole / Oluwaseun Ladipo-Ajayi / Justina O Seyi-Olajide / Babasola Okusanya / Ogechi Abazie / Iyabo Y Ademuyiwa / Amanda Onwuka / Tu Tran / Ayomide Makanjuola / Shailvi Gupta / Riinu Ots / Ewen M Harrison / Dan Poenaru /
    Benedict C Nwomeh

    PLoS ONE, Vol 14, Iss 10, p e

    Implications for paediatric surgical capacity-building.

    2019  Volume 0223423

    Abstract: Background In many low- and middle-income countries, data on the prevalence of surgical diseases have been derived primarily from hospital-based studies, which may lead to an underestimation of disease burden within the community. Community-based ... ...

    Abstract Background In many low- and middle-income countries, data on the prevalence of surgical diseases have been derived primarily from hospital-based studies, which may lead to an underestimation of disease burden within the community. Community-based prevalence studies may provide better estimates of surgical need to enable proper resource allocation and prioritization of needs. This study aims to assess the prevalence of common surgical conditions among children in a diverse rural and urban population in Nigeria. Methods Descriptive cross-sectional, community-based study to determine the prevalence of congenital and acquired surgical conditions among children in a diverse rural-urban area of Nigeria was conducted. Households, defined as one or more persons 'who eat from the same pot' or slept under the same roof the night before the interview, were randomized for inclusion in the study. Data was collected using an adapted and modified version of the interviewer-administered questionnaire-Surgeons OverSeas Assessment of Surgical Need (SOSAS) survey tool and analysed using the REDCap web-based analytic application. Main results Eight-hundred-and-fifty-six households were surveyed, comprising 1,883 children. Eighty-one conditions were identified, the most common being umbilical hernias (20), inguinal hernias (13), and wound injuries to the extremities (9). The prevalence per 10,000 children was 85 for umbilical hernias (95% CI: 47, 123), and 61 for inguinal hernias (95% CI: 34, 88). The prevalence of hydroceles and undescended testes was comparable at 22 and 26 per 10,000 children, respectively. Children with surgical conditions had similar sociodemographic characteristics to healthy children in the study population. Conclusion The most common congenital surgical conditions in our setting were umbilical hernias, while injuries were the most common acquired conditions. From our study, it is estimated that there will be about 2.9 million children with surgically correctable conditions in the nation. This suggests an ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 380
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: A global point prevalence survey of antimicrobial use in neonatal intensive care units

    Pavel Prusakov, PharmD / Debra A. Goff, PharmD / Phillip S. Wozniak, BA / Azraa Cassim, BPharm / Catherine E.A. Scipion, MD / Soledad Urzúa, MD / Andrea Ronchi, MD / Lingkong Zeng, MD / Oluwaseun Ladipo-Ajayi, MBChB / Noelia Aviles-Otero, MD / Chisom R. Udeigwe-Okeke, MBBS / Rimma Melamed, MD / Rita C. Silveira, MD / Cinzia Auriti, MD / Claudia Beltrán-Arroyave, MD / Elena Zamora-Flores, MD / Maria Sanchez-Codez, MD / Eric S. Donkor, PhD / Satu Kekomäki, MD /
    Nicoletta Mainini, MD / Rosalba Vivas Trochez, MD / Jamalyn Casey, PharmD / Juan M. Graus, MD / Mallory Muller, PharmD / Sara Singh, MBBS / Yvette Loeffen, MD / María Eulalia Tamayo Pérez, MD / Gloria Isabel Ferreyra, MD / Victoria Lima-Rogel, MD / Barbara Perrone, MD / Giannina Izquierdo, MD / María Cernada, MD / Sylvia Stoffella, PharmD / Sebastian Okwuchukwu Ekenze, MD / Concepción de Alba-Romero, MD / Chryssoula Tzialla, MD / Jennifer T. Pham, PharmD / Kenichiro Hosoi, MD / Magdalena Cecilia Calero Consuegra, MD / Pasqua Betta, MD / O. Alvaro Hoyos, MD / Emmanuel Roilides, MD / Gabriela Naranjo-Zuñiga, MD / Makoto Oshiro, MD / Victor Garay, MD / Vito Mondì, MD / Danila Mazzeo, MD / James A. Stahl, PharmD / Joseph B. Cantey, MD / Juan Gonzalo Mesa Monsalve, MD

    EClinicalMedicine, Vol 32, Iss , Pp 100727- (2021)

    The no-more-antibiotics and resistance (NO-MAS-R) study

    2021  

    Abstract: Background: Global assessment of antimicrobial agents prescribed to infants in the neonatal intensive care unit (NICU) may inform antimicrobial stewardship efforts. Methods: We conducted a one-day global point prevalence study of all antimicrobials ... ...

    Abstract Background: Global assessment of antimicrobial agents prescribed to infants in the neonatal intensive care unit (NICU) may inform antimicrobial stewardship efforts. Methods: We conducted a one-day global point prevalence study of all antimicrobials provided to NICU infants. Demographic, clinical, and microbiologic data were obtained including NICU level, census, birth weight, gestational/chronologic age, diagnoses, antimicrobial therapy (reason for use; length of therapy), antimicrobial stewardship program (ASP), and 30-day in-hospital mortality. Findings: On July 1, 2019, 26% of infants (580/2,265; range, 0–100%; median gestational age, 33 weeks; median birth weight, 1800 g) in 84 NICUs (51, high-income; 33, low-to-middle income) from 29 countries (14, high-income; 15, low-to-middle income) in five continents received ≥1 antimicrobial agent (92%, antibacterial; 19%, antifungal; 4%, antiviral). The most common reasons for antibiotic therapy were “rule-out” sepsis (32%) and “culture-negative” sepsis (16%) with ampicillin (40%), gentamicin (35%), amikacin (19%), vancomycin (15%), and meropenem (9%) used most frequently. For definitive treatment of presumed/confirmed infection, vancomycin (26%), amikacin (20%), and meropenem (16%) were the most prescribed agents. Length of therapy for culture-positive and “culture-negative” infections was 12 days (median; IQR, 8–14) and 7 days (median; IQR, 5–10), respectively. Mortality was 6% (42%, infection-related). An NICU ASP was associated with lower rate of antibiotic utilization (p = 0·02). Interpretation: Global NICU antibiotic use was frequent and prolonged regardless of culture results. NICU-specific ASPs were associated with lower antibiotic utilization rates, suggesting the need for their implementation worldwide. Funding: Merck & Co.; The Ohio State University College of Medicine Barnes Medical Student Research Scholarship
    Keywords Global point prevalence study ; Neonatal infection ; Neonatal antimicrobial stewardship ; Antibiotics ; Antifungal ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Paediatric surgical outcomes in sub-Saharan Africa

    Niyi Ade-Ajayi / Dan Poenaru / Damian Clarke / Stephen Tabiri / Larry Akoko / Sharon Cox / Toru Shimizu / Bassey Edem / Kokila Lakhoo / Zaitun M Bokhary / Adesoji Ademuyiwa / Felix Alakaloko / Emmanuel Ameh / Theophilus Teddy Kojo Anyomih / Rouma Bankole / Bruce Bvulani / Milind Chitnis / Miliard Derbew / Stella Eguma /
    Omolara Faboya / Jacques Fadhili Bake / Intisar Hisham / Nasser Kakembo / Bertille Ki / Phyllis Kisa / Rashmi Kumar / Jerome Loveland / Bothwell Mbuwayesango / Mulewa Mulenga / Emmanuel Owusu Abem / Yona Ringo / John Sekabira / Albert Wandaogo / Anne Wesonga / Ali Hamad / Naomi Jane Wright / Abdelbasit E Ali / Ainhoa Costas-Chavarri / Samuel Osei-Nketiah / William Appeadu-Mensah / Opeoluwa Adesanya / Olalekan Ajai / Aminu Mohammad / Stephanie Van Straten / Robert Jaich / Osman Imoro / Lawal Abdullahi / Roel Matos-Puig / Andrew JM Leather / Ademola Olusegun Talabi / Oludayo Adedapo Sowande / Christopher Bode / Taiwo Akeem Lawal / Samson Olori / Reitze Rodseth / Andre Theron / Emily Rose Smith / Alessandra Bisquera / Anyanwu Lofty John-Chukwuemeka / Justine Seyi-Olajide / Bernadette Béré / Luc Malemo / Elisee Bake / Nwokoro Collins / Aberibigbe M. O. Shonubi / Daniel Sidler / Houégban Romeo / Gbenou Antoine Seraphin / Eugene Zoumenou / Béré Bernadette / Bandré Emile / Tapsoba W. Toussaint / Kabre Yvette / Manuela Ehua / Agbara Kouame / Moulot Olivier / Nandiolo Rose / Mesay Hailemariam Asfaw / Gudeta Didi / Hanna Getachew / Woubedil Kiflu / Samuel Negash / Tihitiena Negussie / Amezene Tadesse / Fiseha Temesgen / Afua Hesse / Francis Atidana Abantanga / Adakudugu Ida / Martin Kyere / Anwar Sadat Seidu / Paul M. Wondoh / Thomas Kirengo / Michael Ganey / Michael Mwachiro / Robert K Parker / Sinkeet Ranketi / Bitiel Banda / Caroline Melhado / Biplab Nandi / Mohakhelha Nyamulani / Johannes Verweij / Moustapha Helle / Paschal Anyanwu / Matthias Igoche / Elizabeth Ogboli-Nwasor / Baba Suleiman / Sholadoye Tunde Talib / Mustapha Abdulazeez / Farinyaro Aliyu / Aliyu Mohammed / Terlumun Patrick / Charles Soo / Akinlabi Emmanuel Ajao / Olayemi Anthony Ajiboye / Michael Abel Alao / Odion-Obomhense Kesiena Helen / Adenike Odewabi / Anuoluwapo Aremo / Taiwo Jones Olaoluwa / Odi Temitope / Kayode Bamigbola / E Uduehe Enono / Abdulsalam Moruf / Roland I Osuoji / Omolara M. Williams / Fatuga Adedeji / Ihediwa Chibuike / Ibironke Desalu / Olumide Abiodun Elebute / Charles Ememonu / Oluwaseun Ladipo-Ajayi / Sola Kushimo / Kayode Olayade / Adebambo Olowu / Okechukwu Hyginus Ekwunife / Victor Ifeanyichukwu Modekwe / Obiechina Sylvester Okwuchukwu / Ngozi Chidinma Osuji / Ezidiegwu Ugochukwu Stanley / Jideofor Okechukwu Ugwu / Chuka Ifeanyichukwu Ugwunne / Collins Chijioke Adumah / Lukmon Amosu / Ibukunolu Ogundele / Aderibigbe M. O. Shonubi / Felix Kumolalo / Olakayode Ogundoyin / Dare Olulana / John Chinda / Osagie Olabisi / Akan Inyang / Ijeoma Esther Nwachukwu / Nurudeen Toyin Abdulraheem / Lukman O. Abdur-Rahman / James O. Adeniran / Muslimat A. Alada / Abdulrasheed A. Nasir / David C. Nwosu / Christopher C Amah / Sebastian Okwuchukwu Ekenze / Uchechukwu Obiora Ezomike / Emmanuel I. Nwangwu / Ijeoma C. Obianyo / Nene E Obianyo / Nwankwo Elochukwu Perpetua / Alfred T Aggo / Tobin Maxwell / Philemon Okoro / James A. Brown / Moses Kasumba / Steve Kyota / Joy Robinson / Seo-Hwa Chung / Savannah smit / Andrew Grieve / Charles Carapinha / Mie Elsen / Nayha Gautam / Shamaman Harilal / Sanele Madziba / Hansraj Mangray / Babalwa Nondela / Ria Naidoo / Arasha Thotharam / Kondjela Sara Hamunyela / Corne De Vos / Enas Musa Ismail / Robert Bahati / Peter Dattani / Ezekiel Kambona / Silas Msangi / Komla Gnassingbé / Hamza Doles Sama / Mary T Nabukenya / Emma Lillie / Rae Oranmore-Brown / Hope Phiri / Victoria Simiyu / Tungamirai Gwatirisa / Houessou Gandjehou / Ebassa Karl / Goutam Chowdhury / Alagie Manneh / Michael Amoah / Boateng Nimako / Allan Kochi / Connie Keung / Robert Kuremu / Heuric Rakotomalala / Habou Oumarou / Okafor David / Faruk A Suleiman / Faturoti Olubukola / Innocent Igwilo / Alwanlehi Eighemhenrio / Andrew Shitta / Musa Ibrahim Zarenawa / Iyekeoretin Evbuomwan / Wabada Samuel / Emmanuel Kayibanda / Joseph Lule / Riikka Valjakka

    BMJ Global Health, Vol 6, Iss

    a multicentre, international, prospective cohort study

    2021  Volume 9

    Keywords Medicine (General) ; R5-920 ; Infectious and parasitic diseases ; RC109-216
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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