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  1. Article ; Online: Mental Health Screening in Pediatric Primary Care: Factors Associated With Screening Completion and Elevated Scores.

    Habayeb, Serene / Onofaro, Kayla C / Hawila, Nour / Druskin, Lindsay R / Godoy, Leandra / Long, Melissa

    Clinical pediatrics

    2022  Volume 62, Issue 6, Page(s) 584–591

    Abstract: This study aimed to examine predictors of complete and elevated youth mental health screens. Parents of 4- to 11-year-old children completed the Strengths and Difficulties Questionnaire (SDQ) during a routine, universal mental health screening initiative ...

    Abstract This study aimed to examine predictors of complete and elevated youth mental health screens. Parents of 4- to 11-year-old children completed the Strengths and Difficulties Questionnaire (SDQ) during a routine, universal mental health screening initiative in primary care. Bivariate logistic regressions were run to examine associations between independent (visit age, sex, race/ethnicity, language, insurance, and guardian) and dependent variables (screening completion and elevated SDQ score). Parents of younger and Spanish-speaking (vs English-speaking) children were less likely to have a complete SDQ screen. Among those with complete SDQ screens, older children, male children, those with public or no insurance, and those who had a mother (vs father) complete the screener were more likely to have an elevated score. Understanding patterns of screening completion rates and predictors of elevated screens provides valuable information to improve resource mapping and planning. Findings can inform mental health screening implementation and optimization within primary care.
    MeSH term(s) Female ; Adolescent ; Child ; Humans ; Male ; Child, Preschool ; Mental Health ; Surveys and Questionnaires ; Mental Disorders/diagnosis ; Mass Screening ; Parents/psychology ; Primary Health Care
    Language English
    Publishing date 2022-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228221139983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Race-specific prostate cancer outcomes in a cohort of low and favorable-intermediate risk patients who underwent external beam radiation therapy from 1990 to 2017.

    Stroup, Sean P / Robertson, Audry H / Onofaro, Kayla C / Santomauro, Michael G / Rocco, Nicholas R / Kuo, Huai-Ching / Chaurasia, Avinash R / Streicher, Samantha / Nousome, Darryl / Brand, Timothy C / Musser, John E / Porter, Christopher R / Rosner, Inger L / Chesnut, Gregory T / D'Amico, Anthony / Lu-Yao, Grace / Cullen, Jennifer

    Cancer medicine

    2022  Volume 11, Issue 24, Page(s) 4756–4766

    Abstract: Background: Previous research exploring the role of race on prostate cancer (PCa) outcomes has demonstrated greater rates of disease progression and poorer overall survival for African American (AA) compared to Caucasian American (CA) men. The current ... ...

    Abstract Background: Previous research exploring the role of race on prostate cancer (PCa) outcomes has demonstrated greater rates of disease progression and poorer overall survival for African American (AA) compared to Caucasian American (CA) men. The current study examines self-reported race as a predictor of long-term PCa outcomes in patients with low and favorable-intermediate risk disease treated with external beam radiation therapy (EBRT).
    Methods: This retrospective cohort study examined patients who were consented to enrollment in the Center for Prostate Disease Research Multicenter National Database between January 01, 1990 and December 31, 2017. Men self-reporting as AA or CA who underwent EBRT for newly diagnosed National Comprehensive Cancer Network-defined low or favorable-intermediate risk PCa were included. Dependent study outcomes included: biochemical recurrence-free survival, (ii) distant metastasis-free survival, and (iii) overall survival. Each outcome was modeled as a time-to-event endpoint using race-stratified Kaplan-Meier estimation curves and multivariable Cox proportional hazards analysis.
    Results: Of 840 men included in this study, 268 (32%) were AA and 572 (68%) were CA. The frequency of biochemical recurrence, distant metastasis, and deaths from any cause was 151 (18.7%), 29 (3.5%), and 333 (39.6%), respectively. AA men had a significantly younger median age at time of EBRT and slightly higher biopsy Gleason scores. Multivariable Cox proportional hazards analyses demonstrated no racial differences in any of the study endpoints.
    Conclusions: These findings reveal no racial disparity in PCa outcomes for AA compared to CA men, in a long-standing, longitudinal cohort of patients with comparable access to cancer care.
    MeSH term(s) Male ; Humans ; Retrospective Studies ; Prostatic Neoplasms/pathology ; Neoplasm Grading ; Black or African American ; White People
    Language English
    Publishing date 2022-05-26
    Publishing country United States
    Document type Multicenter Study ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2659751-2
    ISSN 2045-7634 ; 2045-7634
    ISSN (online) 2045-7634
    ISSN 2045-7634
    DOI 10.1002/cam4.4802
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Race-specific prostate cancer outcomes in a cohort of military health care beneficiaries undergoing surgery: 1990-2017.

    Oehrlein, Nathan / Streicher, Samantha A / Kuo, Huai-Ching / Chaurasia, Avinash / McFadden, Jacob / Nousome, Darryl / Chen, Yongmei / Stroup, Sean P / Musser, John / Brand, Timothy / Porter, Christopher / Rosner, Inger L / Chesnut, Gregory T / Onofaro, Kayla C / Rebbeck, Timothy R / D'Amico, Anthony / Lu-Yao, Grace / Cullen, Jennifer

    Cancer medicine

    2022  Volume 11, Issue 22, Page(s) 4354–4365

    Abstract: Background: There is substantial variability in prostate cancer (PCa) mortality rates across Caucasian American (CA), African American (AA), Asian, and Hispanic men; however, these estimates are unable to disentangle race or ethnicity from confounding ... ...

    Abstract Background: There is substantial variability in prostate cancer (PCa) mortality rates across Caucasian American (CA), African American (AA), Asian, and Hispanic men; however, these estimates are unable to disentangle race or ethnicity from confounding factors. The current study explores survival differences in long-term PCa outcomes between self-reported AA and CA men, and examines clinicopathologic features across self-reported CA, AA, Asian, and Hispanic men.
    Methods: This retrospective cohort study utilized the Center for Prostate Disease Research (CPDR) Multi-center National Database from 1990 to 2017. Subjects were consented at military treatment facilities nationwide. AA, CA, Asian, or Hispanic men who underwent radical prostatectomy (RP) for localized PCa within the first year of diagnosis were included in the analyses. Time from RP to biochemical recurrence (BCR), BCR to metastasis, and metastasis to overall death were evaluated using Kaplan-Meier unadjusted estimation curves and adjusted Cox proportional hazards regression.
    Results: This study included 7067 men, of whom 5155 (73%) were CA, 1468 (21%) were AA, 237 (3%) were Asian, and 207 (3%) were Hispanic. AA men had a significantly decreased time from RP to BCR compared to CA men (HR = 1.25, 95% CI = 1.06-1.48, p = 0.01); however, no difference was observed between AA and CA men for a time from BCR to metastasis (HR = 0.73, 95% CI = 0.39-1.33, p = 0.302) and time from metastasis to overall death (HR = 0.67, 95% CI = 0.36-1.26, p = 0.213).
    Conclusions: In an equal access health care setting, AA men had a shorter survival time from RP to BCR, but comparable survival time from BCR to metastasis and metastasis to overall death.
    MeSH term(s) Male ; Humans ; Retrospective Studies ; Military Health ; Neoplasm Recurrence, Local/pathology ; Prostatic Neoplasms/pathology ; Prostatectomy ; Prostate-Specific Antigen ; Cohort Studies
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2659751-2
    ISSN 2045-7634 ; 2045-7634
    ISSN (online) 2045-7634
    ISSN 2045-7634
    DOI 10.1002/cam4.4787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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