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  1. Book: Drugs for the heart

    Opie, Lionel H. / Gersh, Bernard J.

    (ExpertConsult.com)

    2013  

    Author's details Lionel H. Opie. Co-ed. Bernard J. Gersh
    Series title ExpertConsult.com
    Keywords Cardiovascular Agents / pharmacology ; Cardiovascular Agents / therapeutic use ; Cardiovascular Diseases / drug therapy
    Language English
    Size XIII, 573 S. : zahlr. Ill., graph. Darst.
    Edition 8. ed.
    Publisher Elsevier Saunders
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    Accompanying material Zugang zur Internetausgabe über Code
    HBZ-ID HT017556887
    ISBN 978-1-4557-3322-4 ; 1-4557-3322-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2012 A 5302 order for loan Magazin
    Zugang zur Internetausgabe über Code aus lizenzrechtlichen Gründen nicht verfügbar

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  2. Article ; Online: The acute coronary syndrome revisited: effects and therapeutic modulation of excess metabolic fuel supply.

    Essop, M Faadiel / Opie, Lionel H

    Cardiovascular journal of Africa

    2020  Volume 31, Issue 3, Page(s) 159–161

    MeSH term(s) Acute Coronary Syndrome/drug therapy ; Acute Coronary Syndrome/metabolism ; Acute Coronary Syndrome/physiopathology ; Animals ; Biomarkers/blood ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Dyslipidemias/drug therapy ; Dyslipidemias/metabolism ; Dyslipidemias/physiopathology ; Energy Metabolism/drug effects ; Fatty Acids, Nonesterified/blood ; Fatty Acids, Nonesterified/metabolism ; Humans ; Hyperglycemia/drug therapy ; Hyperglycemia/metabolism ; Hyperglycemia/physiopathology ; Hypoglycemic Agents/therapeutic use ; Hypolipidemic Agents/therapeutic use ; Insulin/therapeutic use ; Myocardium/metabolism
    Chemical Substances Biomarkers ; Blood Glucose ; Fatty Acids, Nonesterified ; Hypoglycemic Agents ; Hypolipidemic Agents ; Insulin
    Language English
    Publishing date 2020-09-28
    Publishing country South Africa
    Document type Journal Article
    ZDB-ID 2383233-2
    ISSN 1680-0745 ; 1996-3467 ; 1015-9657 ; 1995-1892
    ISSN (online) 1680-0745 ; 1996-3467
    ISSN 1015-9657 ; 1995-1892
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Present status of statin therapy.

    Opie, Lionel H

    Trends in cardiovascular medicine

    2015  Volume 25, Issue 3, Page(s) 216–225

    Abstract: Statins are cardioprotective agents that reduce the adverse effects of increased low-density lipoprotein cholesterol (LDL-C) levels. For significantly dyslipidemic persons, who are at higher cardiovascular risk, combined statin therapy substantially ... ...

    Abstract Statins are cardioprotective agents that reduce the adverse effects of increased low-density lipoprotein cholesterol (LDL-C) levels. For significantly dyslipidemic persons, who are at higher cardiovascular risk, combined statin therapy substantially reduces the mortality risk, thus potentially being an ideal risk-reducing combination with added risk reduction by lifestyle changes. Decisions regarding the initiation of statin therapy for primary prevention where the absolute risk reduction is much less are more difficult, involving LDL-C levels and higher C-reactive protein levels. For significantly dyslipidemic persons, combined intense exercise and statin therapy substantially reduces the mortality risk, thus potentially being an ideal risk-reducing combination.
    MeSH term(s) Adult ; Child ; Dyslipidemias/drug therapy ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Primary Prevention/methods ; Risk Reduction Behavior
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2015-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1097434-9
    ISSN 1873-2615 ; 1050-1738
    ISSN (online) 1873-2615
    ISSN 1050-1738
    DOI 10.1016/j.tcm.2014.10.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A Proposal to Incorporate Trial Data Into a Hybrid American College of Cardiology/American Heart Association Algorithm for the Allocation of Statin Therapy in Primary Prevention.

    Opie, Lionel H

    Journal of the American College of Cardiology

    2015  Volume 66, Issue 12, Page(s) 1412–1413

    MeSH term(s) Algorithms ; Evidence-Based Medicine ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Myocardial Infarction/prevention & control ; Primary Prevention ; Stroke/prevention & control
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2015-09-22
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2015.05.082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 196: Show issues

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  5. Article ; Online: What is the need for another new journal?

    Opie, Lionel H

    European heart journal. Cardiovascular pharmacotherapy

    2015  Volume 1, Issue 2, Page(s) 74–75

    Language English
    Publishing date 2015-04
    Publishing country England
    Document type Editorial
    ZDB-ID 2808613-2
    ISSN 2055-6845 ; 2055-6837
    ISSN (online) 2055-6845
    ISSN 2055-6837
    DOI 10.1093/ehjcvp/pvu012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Lifestyle and diet.

    Opie, Lionel H

    Cardiovascular journal of Africa

    2014  Volume 25, Issue 6, Page(s) 298–301

    Abstract: Currently, there is widespread interest in many different diets. The best-known diets include the New Atkins diet in the USA, the Dukan diet in France, and in South Africa the Noakes diet. Two different approaches have emerged, one focusing on a life- ... ...

    Abstract Currently, there is widespread interest in many different diets. The best-known diets include the New Atkins diet in the USA, the Dukan diet in France, and in South Africa the Noakes diet. Two different approaches have emerged, one focusing on a life-long healthy lifestyle and the other emphasising weight loss. These are in fact complementary aims, as will be reviewed and reconciled. Furthermore, besides the dietary approach, there is a valid case for added drug therapy for selected lipid disorders with the use statins. In addition, new drugs are emerging that in the future might eventually considerably reduce the negative health impact of coronary artery disease.
    MeSH term(s) Coronary Disease/epidemiology ; Coronary Disease/rehabilitation ; Diet ; Humans ; Life Style ; Morbidity/trends ; Risk Factors ; South Africa/epidemiology ; Weight Loss/physiology
    Language English
    Publishing date 2014-11
    Publishing country South Africa
    Document type Journal Article ; Review
    ZDB-ID 2383233-2
    ISSN 1680-0745 ; 1996-3467 ; 1015-9657 ; 1995-1892
    ISSN (online) 1680-0745 ; 1996-3467
    ISSN 1015-9657 ; 1995-1892
    DOI 10.5830/CVJA-2014-063
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  7. Article ; Online: Cognitive decline: mechanisms and proposed role of the renin-angiotensin-aldosterone system.

    Opie, Lionel H

    Cardiovascular journal of Africa

    2014  Volume 25, Issue 4, Page(s) 149–150

    Abstract: Cognition is derived from the Latin 'cognitio', meaning the process of acquiring knowledge, with related meanings such as study, recognition, social connectivity and discovery. The most crucial components of cognition are the ability to learn and ... ...

    Abstract Cognition is derived from the Latin 'cognitio', meaning the process of acquiring knowledge, with related meanings such as study, recognition, social connectivity and discovery. The most crucial components of cognition are the ability to learn and remember new information, and to function adequately in daily intellectual and interactive aspects of life.Maintenance of normal functional cognitive activity is vitally important in everyday activities. Conversely, cognitive decline, as normally occurs during the ageing process, is a handicap. Such decline varies from moderately inconvenient benign forgetfulness to the devastating losses associated with Alzheimer's disease and brain ischaemia.
    MeSH term(s) Cognition/physiology ; Cognition Disorders/metabolism ; Cognition Disorders/physiopathology ; Humans ; Renin-Angiotensin System/physiology
    Language English
    Publishing date 2014-09-04
    Publishing country South Africa
    Document type Editorial ; Review
    ZDB-ID 2383233-2
    ISSN 1680-0745 ; 1996-3467 ; 1015-9657 ; 1995-1892
    ISSN (online) 1680-0745 ; 1996-3467
    ISSN 1015-9657 ; 1995-1892
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Digitalis reappraised: Still here today, but gone tomorrow?

    Opie, Lionel H

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

    2014  Volume 105, Issue 2, Page(s) 88–89

    Abstract: Digoxin is one of the oldest of drugs acting on the heart and still one of the most frequently used. While in atrial fibrillation digoxin continues to have a valid role in the control of ventricular rate when added to beta-blockers and calcium ... ...

    Abstract Digoxin is one of the oldest of drugs acting on the heart and still one of the most frequently used. While in atrial fibrillation digoxin continues to have a valid role in the control of ventricular rate when added to beta-blockers and calcium antagonists, digoxin for heart failure is no longer a supportable option in view of the negative recent meta-analysis.
    MeSH term(s) Anti-Arrhythmia Agents/therapeutic use ; Atrial Fibrillation/drug therapy ; Digitalis ; Digoxin/therapeutic use ; Heart Failure/drug therapy ; Humans ; Plant Preparations/therapeutic use
    Chemical Substances Anti-Arrhythmia Agents ; Plant Preparations ; Digoxin (73K4184T59)
    Language English
    Publishing date 2014-12-15
    Publishing country South Africa
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 390968-2
    ISSN 2078-5135 ; 0256-9574 ; 0038-2469
    ISSN (online) 2078-5135
    ISSN 0256-9574 ; 0038-2469
    DOI 10.7196/samj.8634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Early intravenous beta-blockade before primary percutaneous coronary intervention gives major benefits, apparently without side effects.

    Opie, Lionel H

    Journal of the American College of Cardiology

    2014  Volume 64, Issue 17, Page(s) 1864

    MeSH term(s) Adrenergic beta-1 Receptor Antagonists/therapeutic use ; Early Medical Intervention ; Humans ; Metoprolol/therapeutic use ; Myocardial Infarction/drug therapy
    Chemical Substances Adrenergic beta-1 Receptor Antagonists ; Metoprolol (GEB06NHM23)
    Language English
    Publishing date 2014-10-28
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2014.07.976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Can dementia be lessened by statins?

    Opie, Lionel H

    Lancet (London, England)

    2014  Volume 384, Issue 9947, Page(s) 953

    MeSH term(s) Alzheimer Disease/drug therapy ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2014-09-13
    Publishing country England
    Document type Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(14)61623-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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