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  1. Article ; Online: Nouvelle AMM : crizotinib dans les tumeurs myofibroblastiques inflammatoires pédiatriques ALK positives.

    Tenaillon, Anne / Orbach, Daniel

    Bulletin du cancer

    2023  Volume 110, Issue 3, Page(s) 248–249

    Title translation Drug approval: Crizotinib in unresectable or refractory ALK-positive pediatric inflammatory myofibroblastic tumors.
    MeSH term(s) Humans ; Child ; Crizotinib ; Drug Approval ; Anaplastic Lymphoma Kinase ; Protein Kinase Inhibitors ; Neoplasms
    Chemical Substances Crizotinib (53AH36668S) ; Anaplastic Lymphoma Kinase (EC 2.7.10.1) ; Protein Kinase Inhibitors
    Language French
    Publishing date 2023-01-28
    Publishing country France
    Document type Letter
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2022.12.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Recommandations harmonisées et analyses de pratique en oncologie pédiatrique.

    Gandemer, Virginie / Orbach, Daniel

    Bulletin du cancer

    2022  Volume 109, Issue 11, Page(s) 1101–1102

    Title translation Importance of harmonized supportive care guidelines and practice analyses in pediatric oncology.
    MeSH term(s) Child ; Humans ; Medical Oncology ; Palliative Care ; Research ; Neoplasms/therapy
    Language French
    Publishing date 2022-09-30
    Publishing country France
    Document type Editorial
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2022.09.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: La population d’adolescents et jeunes adultes atteints de cancer : des spécificités de mieux en mieux reconnues.

    Orbach, Daniel

    Bulletin du cancer

    2016  Volume 103, Issue 12, Page(s) 953–954

    Title translation Teenagers and young adults with cancer: A population with specificities better and better recognized.
    MeSH term(s) Adolescent ; Age Factors ; Human Development ; Humans ; Neoplasms/physiopathology ; Neoplasms/psychology ; Young Adult
    Language French
    Publishing date 2016-12
    Publishing country France
    Document type Editorial
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2016.07.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: False-positive inhibin B leading to oophorectomy for a benign cyst: An unusual trap.

    Glenisson, Mathilde / Brabant, Séverine / Orbach, Daniel / Sarnacki, Sabine / Jodoin, Andréanne

    Pediatric blood & cancer

    2023  , Page(s) e30489

    Language English
    Publishing date 2023-06-08
    Publishing country United States
    Document type Letter
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.30489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Les desmoïdes de l’enfant et de l’adulte : de la chirurgie radicale vers une adaptation thérapeutique moléculaire.

    Penel, Nicolas / Orbach, Daniel

    Bulletin du cancer

    2020  Volume 107, Issue 3, Page(s) 344–345

    Title translation Desmoid type fibromatosis, from radical excision to molecular extirpation.
    MeSH term(s) Adenomatous Polyposis Coli/complications ; Adult ; Age Factors ; Child ; Conservative Treatment/trends ; Female ; Fibromatosis, Abdominal/complications ; Fibromatosis, Abdominal/therapy ; Fibromatosis, Aggressive/complications ; Fibromatosis, Aggressive/therapy ; France ; Humans ; Male ; Neoplasm Recurrence, Local ; Population Surveillance ; Self-Help Groups ; Sex Factors
    Language French
    Publishing date 2020-03-16
    Publishing country France
    Document type Editorial
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2020.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Découverte d'une nouvelle mutation dans MYOD1 qui caractérise un sous-groupe de rhabdomyosarcome embryonnaire agressif s'associant à des mutations de la voie PI3K-AKT.

    Orbach, Daniel

    Bulletin du cancer

    2014  Volume 101, Issue 9, Page(s) 776–777

    Title translation Discovery of a new mutation in MYOD1 characterizes a subset of aggressive embryonal rhabdomyosarcoma partnering with mutations of the PI3K-AKT pathway.
    MeSH term(s) Animals ; Chromosomes, Human, Pair 8 ; Female ; Genetic Testing ; Humans ; Male ; Mutation ; MyoD Protein/genetics ; Oncogene Proteins, Fusion/genetics ; PAX7 Transcription Factor/genetics ; Paired Box Transcription Factors/genetics ; Phosphatidylinositol 3-Kinases/genetics ; Proto-Oncogene Proteins c-akt/genetics ; Rhabdomyosarcoma, Alveolar/diagnosis ; Rhabdomyosarcoma, Embryonal/diagnosis ; Rhabdomyosarcoma, Embryonal/genetics
    Chemical Substances MyoD Protein ; Oncogene Proteins, Fusion ; PAX7 Transcription Factor ; Paired Box Transcription Factors ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language French
    Publishing date 2014-09
    Publishing country France
    Document type Comment ; Journal Article
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1684/bdc.2014.2017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Fin de vie en oncologie pédiatrique : ouvrir le débat ?

    Orbach, Daniel / Serinet, Marie-Odile / Burnod, Alexis / Bouleuc, Carole

    Bulletin du cancer

    2022  Volume 110, Issue 1, Page(s) 16–18

    Title translation End of life in pediatric oncology: Is it time to open the debate?
    MeSH term(s) Child ; Humans ; Terminal Care ; Palliative Care ; Medical Oncology ; Death ; Neoplasms/therapy
    Language French
    Publishing date 2022-11-22
    Publishing country France
    Document type Editorial
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2022.11.002
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  8. Article ; Online: Infantile fibrosarcoma: Is spontaneous regression possible?

    Orbach, Daniel / Sparber-Sauer, Monika / Corradini, Nadege / Ferrari, Andrea / Owens, Cormac / Casanova, Michela

    Pediatric blood & cancer

    2023  Volume 70, Issue 11, Page(s) e30623

    MeSH term(s) Humans ; Infant ; Soft Tissue Neoplasms ; Fibrosarcoma
    Language English
    Publishing date 2023-08-14
    Publishing country United States
    Document type Letter
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.30623
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  9. Article ; Online: Fibroblastic orbital tumour with NTRK1 fusion transcript: when TRK inhibitors rescue surgery.

    Nahon-Estève, Sacha / Orbach, Daniel / Le Loarer, François / Hofman, Paul / Lassalle, Sandra

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

    2023  

    Language English
    Publishing date 2023-12-11
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 80091-0
    ISSN 1715-3360 ; 0008-4182
    ISSN (online) 1715-3360
    ISSN 0008-4182
    DOI 10.1016/j.jcjo.2023.11.008
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  10. Article ; Online: Adenoid cystic carcinoma of the parotid and submandibular glands in children and young adults: A population-based study.

    Phillips, Alisa L / Li, Cai / Liang, Jia / Sheyn, Anthony / Rastatter, Jeffrey C / Chelius, Daniel C / Orbach, Daniel / Richard, Celine

    Pediatric blood & cancer

    2024  Volume 71, Issue 5, Page(s) e30928

    Abstract: Objectives: This study aims to analyze the behavior and treatment of adenoid cystic carcinoma (AdCC) in the pediatric and young adult population and to identify factors affecting overall survival (OS).: Materials and methods: The study analyzed ... ...

    Abstract Objectives: This study aims to analyze the behavior and treatment of adenoid cystic carcinoma (AdCC) in the pediatric and young adult population and to identify factors affecting overall survival (OS).
    Materials and methods: The study analyzed salivary gland malignancies in patients aged 0-21 with AdCC histology using the National Cancer Database from 2004 to 2018.
    Results: A total of 72 patients (59.7% parotid, 36.1% submandibular, 1.4% sublingual, 2.8% unspecified) met criteria. Median age was 18 years [range: 0-21]. High-grade dysplasia was present in 67% of cases. Therapy consisted of primary surgery for all cases, regional lymph node dissection (LND) (74%), radiotherapy (71%), chemotherapy (8%), and chemoradiation (7%). The 5-year OS rate was 93.2% [95% confidence interval (CI): 86.9%-99.9%], respectively. Patients who underwent associated LND had improved OS (p = .0083, log-rank test) with a 5-year OS at 82.4% [95% CI: 66.1%-100%] versus 97.6% [95% CI: 93.0%-100%]. A significant difference in OS was found with unfavorable outcomes after positive marginal status: 5-year OS 84.1% [95% CI: 71.0%-99.7%] versus 100% [95% CI: 100%]; p < .001. Adjuvant therapy did not seem to impact the outcome.
    Conclusion: This study confirms that AdCC in children and young adults has an overall good prognosis despite frequent high grade. It suggests that cervical LND may be of importance, but the value of systematic adjuvant therapy is not confirmed. These findings emphasize the importance and relevance of population-based studies in shaping clinical practice and informing the design of future prospective investigations.
    MeSH term(s) Humans ; Young Adult ; Child ; Adolescent ; Carcinoma, Adenoid Cystic/pathology ; Carcinoma, Adenoid Cystic/radiotherapy ; Submandibular Gland/pathology ; Salivary Gland Neoplasms ; Neck Dissection ; Retrospective Studies ; Prognosis
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.30928
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