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  1. Article ; Online: Hypertension Diagnosis and Management in Africa Using Mobile Phones: A Scoping Review.

    Oronti, Iyabosola B / Iadanza, Ernesto / Pecchia, Leandro

    IEEE reviews in biomedical engineering

    2024  Volume 17, Page(s) 197–211

    Abstract: Target 3.4 of the third Sustainable Development Goal (SDG) of the United Nations (UN) General Assembly proposes to reduce premature mortality from non-communicable diseases (NCDs) by one-third. Epidemiological data presented by the World Health ... ...

    Abstract Target 3.4 of the third Sustainable Development Goal (SDG) of the United Nations (UN) General Assembly proposes to reduce premature mortality from non-communicable diseases (NCDs) by one-third. Epidemiological data presented by the World Health Organization (WHO) in 2016 show that out of a total of 57 million deaths worldwide, approximately 41 million deaths occurred due to NCDs, with 78% of such deaths occurring in low-and-middle-income countries (LMICs). The majority of investigations on NCDs agree that the leading risk factor for mortality worldwide is hypertension. Over 75% of the world's mobile phone subscriptions reside in LMICs, hence making the mobile phone particularly relevant to mHealth deployment in Africa. This study is aimed at determining the scope of the literature available on hypertension diagnosis and management in Africa, with particular emphasis on determining the feasibility, acceptability and effectiveness of interventions based on the use of mobile phones. The bulk of the evidence considered overwhelmingly shows that SMS technology is yet the most used medium for executing interventions in Africa. Consequently, the need to define novel and superior ways of providing effective and low-cost monitoring, diagnosis, and management of hypertension-related NCDs delivered through artificial intelligence and machine learning techniques is clear.
    MeSH term(s) Humans ; Artificial Intelligence ; Cell Phone ; Hypertension/diagnosis ; Telemedicine ; Africa ; Noncommunicable Diseases
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Review ; Journal Article
    ISSN 1941-1189
    ISSN (online) 1941-1189
    DOI 10.1109/RBME.2022.3186828
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Development of an artificial intelligence system to identify hypoglycaemia via ECG in adults with type 1 diabetes: protocol for data collection under controlled and free-living conditions.

    Cisuelo, Owain / Stokes, Katy / Oronti, Iyabosola B / Haleem, Muhammad Salman / Barber, Thomas M / Weickert, Martin O / Pecchia, Leandro / Hattersley, John

    BMJ open

    2023  Volume 13, Issue 4, Page(s) e067899

    Abstract: Introduction: Hypoglycaemia is a harmful potential complication in people with type 1 diabetes mellitus (T1DM) and can be exacerbated in patients receiving treatment, such as insulin therapies, by the very interventions aiming to achieve optimal blood ... ...

    Abstract Introduction: Hypoglycaemia is a harmful potential complication in people with type 1 diabetes mellitus (T1DM) and can be exacerbated in patients receiving treatment, such as insulin therapies, by the very interventions aiming to achieve optimal blood glucose levels. Symptoms can vary greatly, including, but not limited to, trembling, palpitations, sweating, dry mouth, confusion, seizures, coma, brain damage or even death if untreated. A pilot study with healthy (euglycaemic) participants previously demonstrated that hypoglycaemia can be detected non-invasively with artificial intelligence (AI) using physiological signals obtained from wearable sensors. This protocol provides a methodological description of an observational study for obtaining physiological data from people with T1DM. The aim of this work is to further improve the previously developed AI model and validate its performance for glycaemic event detection in people with T1DM. Such a model could be suitable for integrating into a continuous, non-invasive, glucose monitoring system, contributing towards improving surveillance and management of blood glucose for people with diabetes.
    Methods and analysis: This observational study aims to recruit 30 patients with T1DM from a diabetes outpatient clinic at the University Hospital Coventry and Warwickshire for a two-phase study. The first phase involves attending an inpatient protocol for up to 36 hours in a calorimetry room under controlled conditions, followed by a phase of free-living, for up to 3 days, in which participants will go about their normal daily activities unrestricted. Throughout the study, the participants will wear wearable sensors to measure and record physiological signals (eg, ECG and continuous glucose monitor). Data collected will be used to develop and validate an AI model using state-of-the-art deep learning methods.
    Ethics and dissemination: This study has received ethical approval from National Research Ethics Service (ref: 17/NW/0277). The findings will be disseminated via peer-reviewed journals and presented at scientific conferences.
    Trial registration number: NCT05461144.
    MeSH term(s) Humans ; Adult ; Diabetes Mellitus, Type 1/complications ; Blood Glucose ; Blood Glucose Self-Monitoring ; Artificial Intelligence ; Pilot Projects ; Social Conditions ; Hypoglycemia/diagnosis ; Hypoglycemia/etiology ; Data Collection ; Electrocardiography ; Observational Studies as Topic
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-067899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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