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  1. Article ; Online: Safety and feasibility of PuraStat

    Ortenzi, Monica / Haji, Amyn

    Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy

    2020  Volume 30, Issue 6, Page(s) 363–368

    Abstract: Introduction: Haemorrhage remains a major cause of morbidity and death in all surgical specialties. The aim of this study was to analyse the feasibility of PuraStat: Material and methods: This was a prospective observational non-randomised study. ... ...

    Abstract Introduction: Haemorrhage remains a major cause of morbidity and death in all surgical specialties. The aim of this study was to analyse the feasibility of PuraStat
    Material and methods: This was a prospective observational non-randomised study. Consecutive patients undergoing laparoscopic colorectal surgery were enrolled. Inclusion criterion was the need employ a secondary method of haemostasis when traditional methods such as conventional pressure or utilization of energy devices to control the bleeding were either insufficient or not recommended.
    Results: Twenty patients were enrolled. The mean time to apply the product was 40 secs (±17 secs), whereas the mean time to achieve haemostasis was 17.5 secs (±3.5 secs). There were no post-operative complications in this cohort of 20 patients. Mean operative time overall was 185 mins (±45.2 mins). None of the patients experienced delayed post-operative bleeding and the mean hospital stay was five days (±3,4).
    Conclusions: We demonstrated that PuraStat
    MeSH term(s) Colorectal Surgery/adverse effects ; Digestive System Surgical Procedures ; Feasibility Studies ; Humans ; Laparoscopy ; Treatment Outcome
    Language English
    Publishing date 2020-03-14
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1317160-4
    ISSN 1365-2931 ; 1364-5706
    ISSN (online) 1365-2931
    ISSN 1364-5706
    DOI 10.1080/13645706.2020.1739711
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Another Brick in the Wall: We Need More Education!

    Montori, Giulia / Botteri, Emanuele / Sartori, Alberto / Ortenzi, Monica / Podda, Mauro / Agresta, Ferdinando

    Surgical laparoscopy, endoscopy & percutaneous techniques

    2023  Volume 33, Issue 1, Page(s) 2–3

    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1475108-2
    ISSN 1534-4908 ; 1530-4515 ; 1051-7200
    ISSN (online) 1534-4908
    ISSN 1530-4515 ; 1051-7200
    DOI 10.1097/SLE.0000000000001129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Nationwide analysis of inpatient laparoscopic ventral hernia repair in Italy from 2015 to 2020.

    Botteri, Emanuele / Ortenzi, Monica / Williams, Sophie / Balla, Andrea / Podda, Mauro / Guerrieri, Mario / Sartori, Alberto

    Updates in surgery

    2023  Volume 75, Issue 6, Page(s) 1661–1670

    Abstract: Since 2010, several guidelines and consensus papers have been proposed to support surgeons in the decision-making process (Cuccurullo et al. in Hernia 17(5):557-566, 2013; Silecchia et al. in Surg Endosc 29:2463-2484, 2015; Bittner et al. in Surg Endosc ... ...

    Abstract Since 2010, several guidelines and consensus papers have been proposed to support surgeons in the decision-making process (Cuccurullo et al. in Hernia 17(5):557-566, 2013; Silecchia et al. in Surg Endosc 29:2463-2484, 2015; Bittner et al. in Surg Endosc 33(11):3511-3549, 2015) with the conclusion that laparoscopic repair (LR) has gained popularity in the treatment of IH.To date, however, it is not yet clear as to the uptake of LR for IH on national basis. Only dated studies encompassing of all types of incisional hernia repairs are available in literature (Bisgaard et al. in Br J Surg 96:1452-1457, 2009). The aim of our study is to present a snapshot of Italian data for LR of ventral hernias, over a 6 years period, including volume of LR, procedural features and major postoperative outcomes. Data were extracted from the Italian Hospital Information System (HIS) that collects clinical and administrative information regarding each hospital admission of every patient discharged from any hospital in Italy. Using Hospital Discharge records regional Databases (HDD), all laparoscopic ventral hernia procedures carried out in public and private hospitals between 2015 and 2020, in patients over 18 years and resident in Italy, were collected based on diagnosis and procedure codes. The National Agency for Regional Health Services (AgeNaS) oversees the management and analysis of data. All hospital admissions that occurred between 2015 and 2020 were analyzed.A total of 154,546 incisional hernia repairs were performed in Italy from 2015 to 2020. Of these, 20,789 (13.45%) were minimally invasive repairs. The number of procedures performed increased significantly over time, constituting 11.96 and 15.24% of all procedures performed in 2015 and 2020 respectively. However, considering the whole period, the mean annual change was-5.58% (CI - 28.6% to 17.44%; p < 0.0001).Urgent minimally invasive repairs were performed in 1968 cases (1.27%). The absolute rate of laparoscopically treated patients needing an urgent surgical procedure increased overtime (from 7.36% in 2015 to 13.418% in 2020). The mean annual change registered over the whole period was 7.42%. 92% (CI - 0.03 to 14.09%; p < 0.0001). However, when considering the period from 2015 to 2019, the mean annual change was 10.42% (CI 6.35 to 14.49%; p < 0.0001). To our knowledge this is the first nationwide Italian report presenting the national workload of surgical units and the main perioperative features of minimally invasive surgery for ventral hernia repairs.
    MeSH term(s) Humans ; Herniorrhaphy/methods ; Incisional Hernia/surgery ; Inpatients ; Hernia, Ventral/surgery ; Hernia, Ventral/etiology ; Laparoscopy/methods ; Surgical Mesh
    Language English
    Publishing date 2023-03-14
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-023-01460-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prospective Italian validation of the Vaizey and Wexner and fecal incontinence severity index (FISI) questionnaires.

    Ortenzi, Monica / Guerrieri, Mario / Saraceno, Federica / Reggiani, Angelica / Lepiane, Pasquale / Sileri, Pierpaolo / Balla, Andrea

    Updates in surgery

    2023  Volume 75, Issue 6, Page(s) 1617–1623

    Abstract: Several objective severity measurement questionnaires of the fecal incontinence (FI), are available to describe type, frequency and degree of FI, and their impact on quality of life, aiming to establish baseline scores measure response to treatment over ... ...

    Abstract Several objective severity measurement questionnaires of the fecal incontinence (FI), are available to describe type, frequency and degree of FI, and their impact on quality of life, aiming to establish baseline scores measure response to treatment over time and allow comparison among patients treated using different strategies. Presently, despite their widespread use in clinical practice, none of these questionnaire have been validated in the Italian language. The aim is to test the translated Italian version of the Vaizey and Wexner and Fecal Incontinence Severity Index (FISI) questionnaires assessing their reliability and validity among Italian-speaking patients. Two researchers proficient in spoken English and Italian translated both questionnaires in the Italian language. They independently translated the two questionnaires from English and then they met to produce a single version of the two questionnaires, to solve any possible discrepancy. A forward-backward translation was then obtained by a professional bilingual translator, so as to define the final version of the questionnaires. The questionnaires were independently administered twice to 100 Italian-speaking patients by two different and independent raters. Cronbach's α of the first and second Vaizey and Wexner questionnaire was 0.755 and 0.727, respectively. While Cronbach's α of the first and second FISI questionnaire was 0.810 and 0.806, respectively. Spearman correlation and inter-rater reliability were 0.937 and 0.913 for Vaizey and Wexner questionnaire, respectively, and 0.915 and 0.871 for FISI questionnaire, respectively. Italian version of the Vaizey and Wexner and FISI questionnaires proved good consistency, reliability, reproducibility, showing good psychometric properties.
    MeSH term(s) Humans ; Quality of Life ; Reproducibility of Results ; Prospective Studies ; Fecal Incontinence/diagnosis ; Severity of Illness Index ; Language ; Surveys and Questionnaires ; Italy
    Language English
    Publishing date 2023-06-27
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-023-01567-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Transanal endoscopic microsurgery: indications, tips and long-term results. A single center experience.

    Ortenzi, Monica / Ghiselli, Roberto / Gesuita, Rosaria / Guerrieri, Mario

    Minerva chirurgica

    2020  Volume 75, Issue 3, Page(s) 129–140

    Abstract: Background: Transanal endoscopic microsurgery (TEM) was introduced to combine the curativeness of full thickness excision with minimum morbidity, while traditional rectal surgery is burdened by high morbidity and mortality rates. However, while it is ... ...

    Abstract Background: Transanal endoscopic microsurgery (TEM) was introduced to combine the curativeness of full thickness excision with minimum morbidity, while traditional rectal surgery is burdened by high morbidity and mortality rates. However, while it is still a matter of considerable debate whether local excision is an adequate approach for curative resection of rectal cancer, new minimally invasive operative techniques have been introduced. The purpose of this paper was to show the indications, the tips and long term results of this technique through the review of the largest single-center database available to date. The showed results derived from the single center experience of the Clinica Chirurgica of Polytechnic University of Marche.
    Methods: We retrospectively reviewed a 25-year database from May 1992 to May 2017. We divided the patients into three different groups of patients according to the preoperative diagnosis: rectal cancers, adenomas and other rectal lesions. Rectal adenomas were divided into two groups according to their diameter (> or <5 cm). Rectal cancer patients were divided into two groups according to the preoperative staging: early rectal cancer and irradiated rectal cancer.
    Results: Among the 1324 patients who had rectal tumors excised with TEM at our institution, preoperative histology was rectal adenoma in 729 (55%) patients, adenocarcinoma in 536 (40.5%) patients and other lesions in the remaining 59 (4.4%) patients. 5 years overall survival (OS) and Recurrence free survival (RFS) were 93.3% and 98.6% for patients with rectal adenomas and 86.8% and 70.9% for patients with rectal cancer.
    Conclusions: TEM can be a valid alternative for the treatment of both benign and malignant rectal lesions, further studies are needed to define more specific indications to justify the survival of this technique in the future.
    MeSH term(s) Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Adenoma/mortality ; Adenoma/pathology ; Adenoma/surgery ; Age Factors ; Aged ; Aged, 80 and over ; Databases, Factual/statistics & numerical data ; Female ; Humans ; Italy ; Male ; Middle Aged ; Operative Time ; Progression-Free Survival ; Rectal Neoplasms/mortality ; Rectal Neoplasms/pathology ; Rectal Neoplasms/surgery ; Retrospective Studies ; Transanal Endoscopic Microsurgery/methods ; Treatment Outcome
    Language English
    Publishing date 2020-03-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123603-9
    ISSN 1827-1626 ; 0026-4733
    ISSN (online) 1827-1626
    ISSN 0026-4733
    DOI 10.23736/S0026-4733.20.08201-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Telemedicine in surgery during COVID-19 pandemic: are we doing enough?

    Sartori, Alberto / Balla, Andrea / Agresta, Ferdinando / Guerrieri, Mario / Ortenzi, Monica

    Minerva surgery

    2021  Volume 77, Issue 1, Page(s) 50–56

    Abstract: Introduction: The aim of this systematic review was to report and to analyze if there is and what is the impact of telemedicine in the surgical practice during COVID-19 pandemic. Many authors have posited that the pandemic urged a high implementation of ...

    Abstract Introduction: The aim of this systematic review was to report and to analyze if there is and what is the impact of telemedicine in the surgical practice during COVID-19 pandemic. Many authors have posited that the pandemic urged a high implementation of the telemedicine service even in surgical specialties, however, the impact of this change of the clinical practice has been variably reported and its utilization in general surgery is uncertain.
    Evidence acquisition: All articles from any country written in English, Italian, Spanish, or French, about the use of telemedicine for indication to surgical treatment or for 30-day postoperative follow-up in general surgery during the COVID 19 outbreak, from the March 1, 2020, to December 1, 2020, were included.
    Evidence synthesis: Two hundred nine articles were fully analyzed, and 207 further articles were excluded. Finally, 2 articles, both published in October 2020, were included in the present systematic review.
    Conclusions: In conclusion, the rapid spread of SARS-CoV-2 pandemic has forced to review the traditional methods to deliver surgical assistance and urged surgeons to find alternative methods to continue their practice. The literature about this topic is yet scarce and many questions regarding its efficacy in improving patients' health, cost-effectiveness and user satisfaction remain unsolved.
    MeSH term(s) Aftercare/statistics & numerical data ; COVID-19/epidemiology ; General Surgery/statistics & numerical data ; Humans ; Pandemics ; Postoperative Care/statistics & numerical data ; SARS-CoV-2 ; Telemedicine/statistics & numerical data
    Language English
    Publishing date 2021-10-25
    Publishing country Italy
    Document type Journal Article ; Systematic Review
    ZDB-ID 3067899-7
    ISSN 2724-5438
    ISSN (online) 2724-5438
    DOI 10.23736/S2724-5691.21.09100-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19 pandemic: is it time for shared surgical guidelines? A systematic review of the literature.

    Ortenzi, Monica / Balla, Andrea / Botteri, Emanuele / Lepiane, Pasquale / Guerrieri, Mario / Arezzo, Alberto / Sartori, Alberto

    Minerva surgery

    2022  Volume 77, Issue 2, Page(s) 171–179

    Abstract: Introduction: The recent COrona Virus Disease 2019 (COVID-19) pandemic caused a massive disruption of surgical activity and after a year from its first outbreak surgeons still struggle to keep their regular activity coexisting with the virus exhausting ... ...

    Abstract Introduction: The recent COrona Virus Disease 2019 (COVID-19) pandemic caused a massive disruption of surgical activity and after a year from its first outbreak surgeons still struggle to keep their regular activity coexisting with the virus exhausting requests of healthcare resources. The aim of this paper is to offer a comprehensive overview of the most important recommendations by the International Guidelines about general surgery, and possibly to invite building common shared guidelines to preserve the potential to provide surgical assistance despite the pandemic.
    Evidence acquisition: This systematic review was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analysis statement. PubMed, Embase, Cochrane and Web of Science databases were searched.
    Evidence synthesis: The searches revealed a total of 18579 articles published up to the end of February 2021. Five articles published between March and May 2020, were included in the present study: Guidelines from The European Society of Trauma and Emergency Surgery (ESTES), The Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) and The European Association for Endoscopic Surgeons (EAES), The Endoscopic and Laparoscopic Surgeons of Asia (ELSA), The European Hernia Society (EHS) and The International Organization for the Study of Inflammatory Bowel Disease (IOS-IBD).
    Conclusions: In the likely scenario that the SARS-CoV-2 pandemic will become an endemic chronic problem, we should not be forced to choose between COVID-19 or surgery in the future and find a way to make both coexisting.
    MeSH term(s) COVID-19/epidemiology ; Humans ; Laparoscopy ; Pandemics ; SARS-CoV-2 ; Surgeons
    Language English
    Publishing date 2022-04-12
    Publishing country Italy
    Document type Journal Article ; Systematic Review
    ZDB-ID 3067899-7
    ISSN 2724-5438
    ISSN (online) 2724-5438
    DOI 10.23736/S2724-5691.21.09166-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Nationwide analysis of laparoscopic groin hernia repair in Italy from 2015 to 2020.

    Ortenzi, Monica / Botteri, Emanuele / Balla, Andrea / Podda, Mauro / Guerrieri, Mario / Sartori, Alberto

    Updates in surgery

    2022  

    Abstract: Since its introduction, the minimally invasive treatment of groin hernias has become widely accepted as a viable alternative to open surgery. Still, the rates and reasons for its adoption vary highly among countries and the regions within a country. ... ...

    Abstract Since its introduction, the minimally invasive treatment of groin hernias has become widely accepted as a viable alternative to open surgery. Still, the rates and reasons for its adoption vary highly among countries and the regions within a country. After almost thirty years since its introduction, its spread is still limited. The present study, conducted under the auspices of AGENAS (Italian National Agency for Regional Services), aims at giving a snapshot of the spreading of minimally invasive and robotic techniques for the treatment of groin hernia in Italy. This study is retrospective, with data covering the period from 1st January 2015 to 31st December 2020. AGENAS provided data using the operation and diagnosis codes used at discharge and reported in the International Classification of Diseases 9th revision (ICD9 2002 version). Admissions performed on an outpatient basis, i.e., without an overnight stay of at least one night in hospital, were excluded. A total of 33,925 laparoscopic hernia repairs were performed during the considered period. Overall, a slight increase in the number of procedures performed was observed from 2015 to 2019, with a mean annual change of 8.60% (CI: 6.46-10.74; p < 0.0001). The number of laparoscopic procedures dropped in 2020, and when considering the whole period, the mean annual change was - 0.98% (CI: - 7.41-5.45; p < 0.0001). Urgent procedures ranged from 335 in 2015 to 508 in 2020 referring to absolute frequencies, and from 0.87% to 9.8% in relative frequencies of overall procedures in 2017 and 2020, respectively (mean = 4.51%; CI = 3.02%-6%; p < 0.001). The most relevant observation that could be made according to our analysis was that the adoption of the laparoscopic approach knew a slow but steady increase from 2015 onward.
    Language English
    Publishing date 2022-09-07
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-022-01374-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Transanal endoscopic microsurgery after the attempt of endoscopic removal of rectal polyps.

    Ortenzi, Monica / Arezzo, Alberto / Ghiselli, Roberto / Allaix, Marco Ettore / Guerrieri, Mario / Morino, Mario

    Surgical endoscopy

    2022  Volume 36, Issue 10, Page(s) 7738–7746

    MeSH term(s) Humans ; Microsurgery ; Neoplasm Recurrence, Local/surgery ; Polyps/surgery ; Proctoscopy ; Rectal Neoplasms/surgery ; Transanal Endoscopic Microsurgery ; Treatment Outcome
    Language English
    Publishing date 2022-03-04
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-022-09162-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Minimally invasive approach to incisional hernia in elective and emergency surgery: a SICE (Italian Society of Endoscopic Surgery and new technologies) and ISHAWS (Italian Society of Hernia and Abdominal Wall Surgery) online survey.

    Crepaz, Lorenzo / Sartori, Alberto / Podda, Mauro / Ortenzi, Monica / Di Leo, Alberto / Stabilini, Cesare / Carlucci, Michele / Olmi, Stefano

    Updates in surgery

    2023  Volume 75, Issue 6, Page(s) 1671–1680

    Abstract: Minimally invasive abdominal wall surgery is growing worldwide, with a constant and fast improvement of surgical techniques and surgeons' confidence in treating both primary and incisional hernias (IH). The Italian Society of Endoscopic Surgery and new ... ...

    Abstract Minimally invasive abdominal wall surgery is growing worldwide, with a constant and fast improvement of surgical techniques and surgeons' confidence in treating both primary and incisional hernias (IH). The Italian Society of Endoscopic Surgery and new technologies (SICE) and the ISHAWS (Italian Society of Hernia and Abdominal Wall Surgery) worked together to investigate state of the art in IH treatment in elective and emergency settings in Italy. An online open survey was designed, and Italian surgeons interested in abdominal wall surgery were invited to fill out a 20-point questionnaire on IH surgical procedures performed in their departments. Surgeons were asked to express their points of view on specific questions about technical and clinical variables in IH treatment. Preferred approach in elective IH surgery was minimally invasive (59.7%). Open surgery was the preferred approach in 40.3% of the responses. In emergency settings, open surgery was the preferred approach (65.4%); however, 34.5% of the involved surgeons declare to prefer the laparoscopic/endoscopic approach. Most respondents opted for conversion to open surgery in case of relevant surgical field contamination, with a non-mesh repair of abdominal wall defects. Among those that used the laparoscopic approach in the emergent setting, the majority (74%) used the size of the defect of 5 cm as a decisional cut-off. The spread of minimally invasive approaches to IH repair in emergency surgery in Italy is gaining relevance. Code-sharing through scientific societies can improve clinical practice in different departments and promote a tailored approach to IH surgery.
    MeSH term(s) Humans ; Incisional Hernia/surgery ; Abdominal Wall/surgery ; Hernia, Ventral/surgery ; Herniorrhaphy/methods ; Laparoscopy/methods ; Surgical Mesh
    Language English
    Publishing date 2023-04-18
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-023-01505-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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