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  1. Article: Heats of combustion representative of the carbohydrate mass contained in fruits, vegetables, or cereals

    González Ortiz, Luis Javier

    Food Science & Nutrition, 7(9):3119-3127

    2019  

    Abstract: The obtainment of suitable values for metabolizable energy requires the previous knowledge of accurate and precise values of the heat of combustion of the different macronutrients. Thus, in this work, the heats of combustion of six carbohydrates (glucose, ...

    Abstract The obtainment of suitable values for metabolizable energy requires the previous knowledge of accurate and precise values of the heat of combustion of the different macronutrients. Thus, in this work, the heats of combustion of six carbohydrates (glucose, fructose, sucrose, maltose, starch, and cellulose) were experimentally measured, and such values were statistically compared with equivalent bibliographic values collected in a parallel work (Heats of combustion of the main carbohydrates in vegetable foods: a bibliographic approach, 2019), proposing, for each carbohydrate, an “overall interval” and an actualized representative value, which were estimated considering jointly the bibliographic and experimental information. Besides, a numerical methodology that used such parameters and the relative content of the different carbohydrates in selected foods was proposed, to estimate the global heat of combustion producible by the carbohydrate mass contained in such foods. The results estimated for 68 foods were globalized to propose the following generalized heats of combustion: (a) for fruits: 3.88 kcal/g, (b) for vegetables: 3.98 kcal/g and, and (c) for cereals: 4.13 kcal/g. These results demonstrated that the use of the Atwater's value (4.2 kcal/g of carbohydrate of vegetable source) involves a clear overestimation of the heat of combustion of the carbohydrate mass contained in vegetable source foods.
    Keywords Heats of combustion ; carbohydrates ; cereals ; fruits ; vegetables ; vegetal source foods
    Language English
    Document type Article
    Database Repository for Life Sciences

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  2. Article ; Online: Looking for navigation charts for the journey through dementia.

    Agüera-Ortiz, Luis

    International psychogeriatrics

    2021  Volume 33, Issue 8, Page(s) 747–749

    Language English
    Publishing date 2021-08-23
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1038825-4
    ISSN 1741-203X ; 1041-6102
    ISSN (online) 1741-203X
    ISSN 1041-6102
    DOI 10.1017/S1041610220003889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Role of metabolic reprogramming in pro-inflammatory cytokine secretion from LPS or silica-activated macrophages.

    Marrocco, Antonella / Ortiz, Luis A

    Frontiers in immunology

    2022  Volume 13, Page(s) 936167

    Abstract: In the lungs, macrophages constitute the first line of defense against pathogens and foreign bodies and play a fundamental role in maintaining tissue homeostasis. Activated macrophages show altered immunometabolism and metabolic changes governing immune ... ...

    Abstract In the lungs, macrophages constitute the first line of defense against pathogens and foreign bodies and play a fundamental role in maintaining tissue homeostasis. Activated macrophages show altered immunometabolism and metabolic changes governing immune effector mechanisms, such as cytokine secretion characterizing their classic (M1) or alternative (M2) activation. Lipopolysaccharide (LPS)-stimulated macrophages demonstrate enhanced glycolysis, blocked succinate dehydrogenase (SDH), and increased secretion of interleukin-1 beta (IL-1β) and tumor necrosis factor-alpha (TNF-α). Glycolysis suppression using 2 deoxyglucose in LPS-stimulated macrophages inhibits IL-1β secretion, but not TNF-α, indicating metabolic pathway specificity that determines cytokine production. In contrast to LPS, the nature of the immunometabolic responses induced by non-organic particles, such as silica, in macrophages, its contribution to cytokine specification, and disease pathogenesis are not well understood. Silica-stimulated macrophages activate pattern recognition receptors (PRRs) and NLRP3 inflammasome and release IL-1β, TNF-α, and interferons, which are the key mediators of silicosis pathogenesis. In contrast to bacteria, silica particles cannot be degraded, and the persistent macrophage activation results in an increased NADPH oxidase (Phox) activation and mitochondrial reactive oxygen species (ROS) production, ultimately leading to macrophage death and release of silica particles that perpetuate inflammation. In this manuscript, we reviewed the effects of silica on macrophage mitochondrial respiration and central carbon metabolism determining cytokine specification responsible for the sustained inflammatory responses in the lungs.
    MeSH term(s) Lipopolysaccharides/pharmacology ; Lipopolysaccharides/metabolism ; Silicon Dioxide/pharmacology ; Macrophages ; Macrophage Activation ; Cytokines/metabolism ; Tumor Necrosis Factor-alpha/metabolism
    Chemical Substances Lipopolysaccharides ; Silicon Dioxide (7631-86-9) ; Cytokines ; Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2022-10-21
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.936167
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  4. Article ; Online: Quo vadis Alois?

    Agüera-Ortiz, Luis

    Medicina clinica

    2020  Volume 155, Issue 11, Page(s) 491–493

    Title translation ¿Quo vadis Alois?
    Language Spanish
    Publishing date 2020-09-02
    Publishing country Spain
    Document type Editorial
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.06.028
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  5. Article ; Online: From stigma to haute cuisine: Strategies, agents, and discourses in the revalorisation of Carob as a gourmet product

    Pedret-Massanet, Cecilia / López-Lago Ortiz, Luis / Allen-Perkins, Diego

    International Journal of Gastronomy and Food Science. 2023 Feb. 03, p.100677-

    2023  , Page(s) 100677–

    Abstract: Gourmetisation processes have contributed to the revalorisation of certain foods and cuisines traditionally associated with the lower classes – sometimes stigmatised because of their connection with periods of hardship and considered unfit for human ... ...

    Abstract Gourmetisation processes have contributed to the revalorisation of certain foods and cuisines traditionally associated with the lower classes – sometimes stigmatised because of their connection with periods of hardship and considered unfit for human consumption. This article reviews the gourmetisation dynamics created around carob – a product intimately related to the creation and underpinning of the gastronomic identity and the cultural memory of the inhabitants of the Balearic Islands (Spain). The web of interconnected meanings constructed around this product is examined through an ethnographic analysis of consumers, traders, political actors, and high-level chefs, pastry chefs, and master bakers. The article reviews the strategies and agents involved in the rediscovery and revalorisation of carob as a gourmet product. It also describes the impact of these strategies in the development of different marketing initiatives for its commercial exploitation. Finally, this research examines how the gourmetisation of carob reveals a confluence with current gastronomic trends focused on locally produced, sustainable, and healthier products and the valorisation of tradition as a synonym of “authenticity”.
    Keywords anthropology ; carob ; cuisine ; gastronomy ; humans ; memory ; pastries ; politics ; stigma ; Spain ; Gourmetisation ; Authenticity ; Identity ; Sustainability
    Language English
    Dates of publication 2023-0203
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 2708757-8
    ISSN 1878-450X
    ISSN 1878-450X
    DOI 10.1016/j.ijgfs.2023.100677
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Response to: Reporting the results of a clinical trial across multiple papers, does it matter?

    Gómez-Marcos, Manuel A / García-Ortiz, Luis

    European journal of cardiovascular nursing

    2021  Volume 20, Issue 6, Page(s) 620–621

    Language English
    Publishing date 2021-07-13
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2151245-0
    ISSN 1873-1953 ; 1474-5151
    ISSN (online) 1873-1953
    ISSN 1474-5151
    DOI 10.1093/eurjcn/zvab051
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  7. Article ; Online: Association between Feelings of Trust and Security with Subjective Health among Mexican Migrants in the New York City Area.

    Gaitán-Rossi, Pablo / Vilar-Compte, Mireya / Ferré-Eguiluz, Isabel / Ortiz, Luis / Garcia, Erika

    International journal of environmental research and public health

    2023  Volume 20, Issue 4

    Abstract: The size of the foreign-born population living in the United States makes migrants' health a substantive policy issue. The health status of Mexican immigrants might be affected by the level of social capital and the social context, including the rhetoric ...

    Abstract The size of the foreign-born population living in the United States makes migrants' health a substantive policy issue. The health status of Mexican immigrants might be affected by the level of social capital and the social context, including the rhetoric around immigration. We hypothesize that a diminished perception of trust and safety in the community has a negative impact on self-reported health. In a cross-sectional study, we conducted a survey among 266 Mexican Immigrants in the New York City Area who used the Mexican Consulate between May and June 2019 for regular services provided to documented and undocumented immigrants. A univariate and bivariate descriptive analysis by trust and security items first shows the diversity of the Mexican population living in the US and the conditions of vulnerability. Then, logistic regression models estimate the association between trust and security items with self-reported health status. Results show that safety is consistently associated with good self-rated health, especially when rating the neighborhood, and trust showed mixed results, more reliant to the way it is operationalized. The study illustrates a pathway by which perceptions of the social context are associated with migrants' health.
    MeSH term(s) Female ; Humans ; United States ; Diagnostic Self Evaluation ; Trust ; Cross-Sectional Studies ; New York City ; Emotions ; Transients and Migrants
    Language English
    Publishing date 2023-02-08
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20042981
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  8. Article: Modeling Macrophage Polarization and Its Effect on Cancer Treatment Success.

    Morales, Valentin / Soto-Ortiz, Luis

    Open journal of immunology

    2018  Volume 8, Issue 2, Page(s) 36–80

    Abstract: Positive feedback loops drive immune cell polarization toward a pro-tumor phenotype that accentuates immunosuppression and tumor angiogenesis. This phenotypic switch leads to the escape of cancer cells from immune destruction. These positive feedback ... ...

    Abstract Positive feedback loops drive immune cell polarization toward a pro-tumor phenotype that accentuates immunosuppression and tumor angiogenesis. This phenotypic switch leads to the escape of cancer cells from immune destruction. These positive feedback loops are generated by cytokines such as TGF-
    Language English
    Publishing date 2018-06-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2667300-9
    ISSN 2162-4526 ; 2162-450X
    ISSN (online) 2162-4526
    ISSN 2162-450X
    DOI 10.4236/oji.2018.82004
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  9. Article ; Online: Heat and coronavirus can be twin killers.

    McPhearson, Timon / Mustafa, Ahmed / Ortiz, Luis

    Nature

    2020  Volume 582, Issue 7810, Page(s) 32

    MeSH term(s) Aged ; Air Conditioning/economics ; Air Conditioning/statistics & numerical data ; COVID-19 ; Coronavirus Infections/epidemiology ; Extreme Heat/adverse effects ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Public Health/economics ; Public Health/statistics & numerical data ; Socioeconomic Factors ; Urban Health/statistics & numerical data ; Vulnerable Populations/statistics & numerical data
    Keywords covid19
    Language English
    Publishing date 2020-06-02
    Publishing country England
    Document type Letter
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-020-01627-8
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  10. Article ; Online: What's the relative humidity in tropical caves?

    Mejía-Ortíz, Luis / Christman, Mary C / Pipan, Tanja / Culver, David C

    PloS one

    2021  Volume 16, Issue 9, Page(s) e0250396

    Abstract: Relative humidity (RH) was measured at hourly intervals for approximately one year in two caves at seven stations near Playa del Carmen in Quintana Roo, Mexico. Sistema Muévelo Rico is a 1.1 km long cave with 12 entrances and almost no dark zone. Río ... ...

    Abstract Relative humidity (RH) was measured at hourly intervals for approximately one year in two caves at seven stations near Playa del Carmen in Quintana Roo, Mexico. Sistema Muévelo Rico is a 1.1 km long cave with 12 entrances and almost no dark zone. Río Secreto (Tuch) is a large river cave with more than 40 km of passages, and an extensive dark zone. Given the need for cave specialists to adapt to saturated humidity, presumably by cuticular thinning, the major stress of RH would be its deviation from saturation. RH in Río Secreto (Tuch) was invariant at three sites and displayed short deviations from 100% RH at the other four sites. These deviations were concentrated at the end of the nortes and beginning of the rainy season. Three of the sites in Sistema Muévelo Rico showed a similar pattern although the timing of the deviations from 100% RH was somewhat displaced. Four sites in Sistema Muévelo Rico were more variable, and were analyzed using a measure of amount of time of deviation from 100% RH for each 24 hour period. Strong seasonality was evident but, remarkably, periods of constant high humidity were not the same at all sites. In most Sistema Muévelo Rico sites, there was a detectable 24 hour cycle in RH, although it was quite weak in about half of them. For Río Secreto (Tuch) only one site showed any sign of a 24 hour cycle. The troglomorphic fauna was more or less uniformly spread throughout the caves and did not concentrate in any one area or set of RH conditions. Compared to temperature, RH is much more constant, perhaps even more constant than the amount of light. However, changes in RH as a result of global warming may have a major negative effect on the subterranean fauna.
    MeSH term(s) Caves ; Humidity ; Mexico ; Seasons ; Tropical Climate
    Language English
    Publishing date 2021-09-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0250396
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