Article ; Online: A case of dupilumab-induced psoriasis-like eruption treated with baricitinib.
Skin health and disease
2024 Volume 4, Issue 2, Page(s) e338
Abstract: Dupilumab is a humanized monoclonal antibody against the interleukin (IL)-4 receptor alpha chain that inhibits IL-4 and IL-13 signalling. It is one of the systemic treatments for patients with moderate-to-severe atopic dermatitis (AD), which provides ... ...
Abstract | Dupilumab is a humanized monoclonal antibody against the interleukin (IL)-4 receptor alpha chain that inhibits IL-4 and IL-13 signalling. It is one of the systemic treatments for patients with moderate-to-severe atopic dermatitis (AD), which provides favourable safety and efficacy. We report a case of psoriasis-like eruption induced by dupilumab as an adverse effect in a patient with AD, immediately remitted after switching to baricitinib, which inhibits JAK1/2. Moreover, the atopic skin lesion also simultaneously went into remission upon baricitinib treatment. Baricitinib could be a favourable option for patients with AD who develop dupilumab-induced psoriasis-like eruption. |
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Language | English |
Publishing date | 2024-01-16 |
Publishing country | England |
Document type | Case Reports |
ISSN | 2690-442X |
ISSN (online) | 2690-442X |
DOI | 10.1002/ski2.338 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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