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  1. Article ; Online: The impact of biomembranes and their dynamics on organismic aging: insights from a fungal aging model.

    Osiewacz, Heinz D

    Frontiers in aging

    2024  Volume 5, Page(s) 1356697

    Abstract: Biomembranes fulfill several essential functions. They delimitate cells and control the exchange of compounds between cells and the environment. They generate specialized cellular reaction spaces, house functional units such as the respiratory chain (RC), ...

    Abstract Biomembranes fulfill several essential functions. They delimitate cells and control the exchange of compounds between cells and the environment. They generate specialized cellular reaction spaces, house functional units such as the respiratory chain (RC), and are involved in content trafficking. Biomembranes are dynamic and able to adjust their properties to changing conditions and requirements. An example is the inner mitochondrial membrane (IMM), which houses the RC involved in the formation of adenosine triphosphate (ATP) and the superoxide anion as a reactive oxygen species (ROS). The IMM forms a characteristic ultrastructure that can adapt to changing physiological situations. In the fungal aging model
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 3076785-4
    ISSN 2673-6217 ; 2673-6217
    ISSN (online) 2673-6217
    ISSN 2673-6217
    DOI 10.3389/fragi.2024.1356697
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Impact of Mitochondrial Architecture, Function, Redox Homeostasis, and Quality Control on Organismic Aging: Lessons from a Fungal Model System.

    Osiewacz, Heinz D

    Antioxidants & redox signaling

    2024  

    Abstract: Significance: ...

    Abstract Significance:
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1483836-9
    ISSN 1557-7716 ; 1523-0864
    ISSN (online) 1557-7716
    ISSN 1523-0864
    DOI 10.1089/ars.2023.0487
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5488: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Book: The mitochondrion in aging and disease

    Osiewacz, Heinz D.

    (Progress in molecular biology and translational science ; 127)

    2014  

    Author's details ed. by Heinz D. Osiewacz
    Series title Progress in molecular biology and translational science ; 127
    Collection
    Language English
    Size XIII, 275, [10] S. : Ill., graph. Darst.
    Edition 1. ed.
    Publisher Elsevier, Acad. Press
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    Note Literaturangaben
    HBZ-ID HT018620709
    ISBN 978-0-12-394625-6 ; 0-12-394625-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Uc I Zs 357 -127- verfügbar in Königswinter Königswinter

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  4. Book: Aging of organisms

    Osiewacz, Heinz D.

    (Biology of aging and its modulation ; 4)

    2003  

    Author's details ed. by Heinz D. Osiewacz
    Series title Biology of aging and its modulation ; 4
    Collection
    Keywords Aging/Physiological aspects ; Organismus ; Altern
    Subject Alterungsprozess ; Altwerden ; Seneszenz ; Alterung ; Lebewesen ; Organismen
    Subject code 571.878
    Language English
    Size 276 S. : Ill., graph. Darst.
    Publisher Kluwer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT013765105
    ISBN 1-4020-1406-6 ; 978-1-4020-1406-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 484 order for loan Magazin

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  5. Article ; Online: To die or not to die - How mitochondrial processes affect lifespan of Podospora anserina.

    Hamann, Andrea / Osiewacz, Heinz D

    Biochimica et biophysica acta. Bioenergetics

    2022  Volume 1863, Issue 6, Page(s) 148568

    Abstract: The filamentous ascomycete Podospora anserina is a well-established model system to study organismic aging. Its senescence syndrome has been investigated for more than fifty years and turned out to have a strong mitochondrial etiology. Several different ... ...

    Abstract The filamentous ascomycete Podospora anserina is a well-established model system to study organismic aging. Its senescence syndrome has been investigated for more than fifty years and turned out to have a strong mitochondrial etiology. Several different mitochondrial pathways were demonstrated to affect aging and lifespan. Here, we present an update of the literature focusing on the cooperative interplay between different processes.
    MeSH term(s) Longevity ; Mitochondria/metabolism ; Podospora/metabolism
    Language English
    Publishing date 2022-05-06
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 60-7
    ISSN 1879-2650 ; 1879-2596 ; 1879-260X ; 1872-8006 ; 1879-2642 ; 1879-2618 ; 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    ISSN (online) 1879-2650 ; 1879-2596 ; 1879-260X ; 1872-8006 ; 1879-2642 ; 1879-2618
    ISSN 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    DOI 10.1016/j.bbabio.2022.148568
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: To die or not to die – How mitochondrial processes affect lifespan of Podospora anserina

    Hamann, Andrea / Osiewacz, Heinz D.

    Biochimica et biophysica acta. 2022 Aug. 01, v. 1863, no. 6

    2022  

    Abstract: The filamentous ascomycete Podospora anserina is a well-established model system to study organismic aging. Its senescence syndrome has been investigated for more than fifty years and turned out to have a strong mitochondrial etiology. Several different ... ...

    Abstract The filamentous ascomycete Podospora anserina is a well-established model system to study organismic aging. Its senescence syndrome has been investigated for more than fifty years and turned out to have a strong mitochondrial etiology. Several different mitochondrial pathways were demonstrated to affect aging and lifespan. Here, we present an update of the literature focusing on the cooperative interplay between different processes.
    Keywords Podospora anserina ; etiology ; longevity ; mitochondria
    Language English
    Dates of publication 2022-0801
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 282711-6
    ISSN 0005-2728 ; 0304-4173
    ISSN 0005-2728 ; 0304-4173
    DOI 10.1016/j.bbabio.2022.148568
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: A Network of Pathways Controlling Cellular Homeostasis Affects the Onset of Senescence in

    Osiewacz, Heinz D / Schürmanns, Lea

    Journal of fungi (Basel, Switzerland)

    2021  Volume 7, Issue 4

    Abstract: ... Research ... ...

    Abstract Research on
    Language English
    Publishing date 2021-03-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof7040263
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  8. Article ; Online: Sordaria macrospora

    Hamann, Andrea / Osiewacz, Heinz D / Teichert, Ines

    Journal of fungi (Basel, Switzerland)

    2022  Volume 8, Issue 10

    Abstract: The formation of fruiting bodies is a highly regulated process that requires the coordinated formation of different cell types. By analyzing developmental mutants, many developmental factors have already been identified. Yet, a complete understanding of ... ...

    Abstract The formation of fruiting bodies is a highly regulated process that requires the coordinated formation of different cell types. By analyzing developmental mutants, many developmental factors have already been identified. Yet, a complete understanding of fruiting body formation is still lacking. In this study, we analyzed developmental mutant pro34 of the filamentous ascomycete
    Language English
    Publishing date 2022-09-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof8101015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Lifespan Increase of

    Schürmanns, Lea / Hamann, Andrea / Osiewacz, Heinz D

    Cells

    2022  Volume 11, Issue 3

    Abstract: The maintenance of cellular homeostasis over time is essential to avoid the degeneration of biological systems leading to aging and disease. Several interconnected pathways are active in this kind of quality control. One of them is autophagy, the ... ...

    Abstract The maintenance of cellular homeostasis over time is essential to avoid the degeneration of biological systems leading to aging and disease. Several interconnected pathways are active in this kind of quality control. One of them is autophagy, the vacuolar degradation of cellular components. The absence of the sorting nexin PaATG24 (SNX4 in other organisms) has been demonstrated to result in impairments in different types of autophagy and lead to a shortened lifespan. In addition, the growth rate and the size of vacuoles are strongly reduced. Here, we report how an oleic acid diet leads to longevity of the wild type and a
    MeSH term(s) Autophagy ; Energy Metabolism ; Humans ; Longevity ; Mitochondria/metabolism ; Oleic Acid/metabolism ; Podospora
    Chemical Substances Oleic Acid (2UMI9U37CP)
    Language English
    Publishing date 2022-02-02
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells11030519
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online ; Thesis: Untersuchungen zur Bedeutung selektiver Autophagie für Alterungsprozesse von Podospora anserina

    Henkel, Vanessa [Verfasser] / Osiewacz, Heinz D. [Gutachter] / Kögel, Donat [Gutachter]

    2023  

    Author's details Vanessa Henkel ; Gutachter: Heinz D. Osiewacz, Donat Kögel
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language German
    Publisher Universitätsbibliothek Johann Christian Senckenberg
    Publishing place Frankfurt am Main
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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