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  1. Book ; Online ; E-Book: Underactive bladder

    Chapple, Christopher R. / Wein, Alan J. / Osman, Nadir I.

    2017  

    Author's details Christopher R. Chapple, Alan J. Wein, Nadir I. Osman editors
    Keywords Allied specialists ; Clinical Symptom Complex ; Diagnosis and treatment ; Functional abnormality ; Urological condition
    Language English
    Size 1 Online-Ressource (xiii, 89 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019157378
    ISBN 978-3-319-43087-4 ; 9783319430850 ; 3-319-43087-4 ; 3319430858
    DOI 10.1007/978-3-319-43087-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Underactive Bladder Versus Bladder Outlet Obstruction: Don't Get Tricked!

    Chapple, Christopher R / Osman, Nadir I

    European urology focus

    2022  Volume 8, Issue 2, Page(s) 388–390

    Abstract: It is not possible to diagnose the cause of voiding difficulty on the basis of a history alone. Bladder underactivity and bladder outlet obstruction cause similar voiding symptoms and also can be associated with storage symptoms. In this mini-review, we ... ...

    Abstract It is not possible to diagnose the cause of voiding difficulty on the basis of a history alone. Bladder underactivity and bladder outlet obstruction cause similar voiding symptoms and also can be associated with storage symptoms. In this mini-review, we consider the factors associated with making a symptomatic diagnosis of either underactive bladder or bladder outlet obstruction. PATIENT SUMMARY: There is overlapping of symptoms for different urinary problems. To differentiate between underactive bladder and bladder outlet obstruction as the underlying cause of lower urinary tract symptoms, an invasive urodynamic study of the bladder is often required.
    MeSH term(s) Humans ; Lower Urinary Tract Symptoms/diagnosis ; Urinary Bladder Neck Obstruction/complications ; Urinary Bladder Neck Obstruction/diagnosis ; Urinary Bladder, Underactive/complications ; Urinary Bladder, Underactive/diagnosis ; Urination ; Urodynamics
    Language English
    Publishing date 2022-03-31
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2022.03.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Female Urethroplasty with a Buccal Mucosa Graft using a Supraurethral Approach.

    Kuo, Tricia / Uçar, Murat / Venugopal, Suresh / Osman, Nadir I / Inman, Richard D / Chapple, Christopher R

    International urogynecology journal

    2024  

    Abstract: Introduction and hypothesis: In the setting of recurrent female urethral stricture, urethroplasty offer the best chance of cure. However, which approach (dorsal or ventral) and which tissue (buccal mucosa, vaginal graft, vaginal flap) remain areas of ... ...

    Abstract Introduction and hypothesis: In the setting of recurrent female urethral stricture, urethroplasty offer the best chance of cure. However, which approach (dorsal or ventral) and which tissue (buccal mucosa, vaginal graft, vaginal flap) remain areas of controversy. In this article and accompanying video, we describe female urethroplasty with a supraurethral approach using a buccal mucosa graft.
    Methods: A stricture of 3 cm in length was observed in the mid urethra. A supraurethral semi-lunar incision was made and dissection was performed up to the stricture. A dorsal urethrotomy was performed and a 3 × 2 cm oral mucosal graft was harvested from the left cheek. The mucosal graft was anastomosed to both urethral edges with running sutures. The graft was fixed to the supraurethral tissue with quilting sutures. A urethral catheter and a suprapubic catheter were left in place for 3 weeks.
    Results: Following removal of the catheters, the patient was able to void satisfactorily with no incontinence. No complications were observed in the urethral area or at the graft harvest site.
    Conclusions: Buccal mucosa graft urethroplasty with a supraurethral approach is a reliable method in the treatment of female urethral stricture.
    Language English
    Publishing date 2024-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1050631-7
    ISSN 1433-3023 ; 0937-3462
    ISSN (online) 1433-3023
    ISSN 0937-3462
    DOI 10.1007/s00192-024-05737-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Is Urethrotomy as Good as Urethroplasty in Men with Recurrent Bulbar Urethral Strictures?

    Osman, Nadir I / Chapple, Christopher R

    European urology

    2020  Volume 78, Issue 4, Page(s) 581–582

    MeSH term(s) Endoscopy ; Humans ; Male ; Urethra/surgery ; Urethral Stricture/diagnosis ; Urethral Stricture/surgery ; Urologic Surgical Procedures, Male/adverse effects
    Language English
    Publishing date 2020-08-11
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2020.07.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1247: Show issues Location:
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    Zs.MO 294: Show issues

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  5. Article ; Online: Asymptomatic COVID-19 Infection in a Patient Evaluated for Ureteric Colic: Radiological Findings and Impact on Management.

    Pang, Karl H / Osman, Nadir I

    Urology

    2020  Volume 141, Page(s) 183–184

    MeSH term(s) Adult ; Betacoronavirus ; COVID-19 ; Colic/complications ; Colic/diagnosis ; Coronavirus Infections/complications ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/therapy ; Female ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; Tomography, X-Ray Computed ; Ureteral Diseases/complications ; Ureteral Diseases/diagnosis
    Keywords covid19
    Language English
    Publishing date 2020-04-24
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2020.04.056
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    Zs.A 1142: Show issues Location:
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    Zs.MO 275: Show issues

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  6. Article ; Online: Erectile and Ejaculatory Function Following Anterior Urethroplasty: A Systematic Review and Meta-analysis.

    Pang, Karl H / Osman, Nadir I / Chapple, Christopher R / Eardley, Ian

    European urology focus

    2022  Volume 8, Issue 6, Page(s) 1736–1750

    Abstract: Context: The degree of change in erectile (EF) and ejaculatory function (EjF) according to validated questionnaires following anterior urethroplasty and different techniques is unclear.: Objective: To investigate the evidence on EF and EjF evaluated ... ...

    Abstract Context: The degree of change in erectile (EF) and ejaculatory function (EjF) according to validated questionnaires following anterior urethroplasty and different techniques is unclear.
    Objective: To investigate the evidence on EF and EjF evaluated via validated questionnaires following anterior urethroplasty.
    Evidence acquisition: A systematic review (PROSPERO ID: CRD42021229797) of the literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. The PubMed and CENTRAL databases were searched on February 1, 2021, with an updated search performed on December 1, 2021. Studies evaluating EF and/or EjF using validated questionnaires in men aged ≥18 yr following anterior urethroplasty were included.
    Evidence synthesis: Overall, 29 studies (two randomised and 27 nonrandomised) were included. The questionnaire most commonly used to evaluate EF and EjF was the International Index of Erectile Function (IIEF) and Male Sexual Health Questionnaire (MSHQ), respectively. The incidence of postoperative erectile dysfunction (ED) was 0-38% and the mean change in EF score according to the IIEF ranged from -4.0 to 2.5. The incidence of postoperative ejaculatory dysfunction (EjD) was 7.7-67% and the mean change in EjF score according to the MSHQ-EjD was 0.7-7.0. Meta-analyses revealed a mean difference of -0.87 (95% confidence interval [CI] -1.50 to -0.23; p = 0.008) in IIEF-EF score and 1.77 (95% CI 0.61-2.93; p = 0.003) in MSHQ-EjF score following anterior urethroplasty.
    Conclusions: EF and EjF may be affected following anterior urethroplasty and men should be counselled appropriately. Owing to the variation in questionnaires and cutoff scores used, EF and EjF outcomes following different urethroplasty techniques are heterogeneous, with limited data from randomised controlled trials. An agreement on questionnaires and cutoff scores should be established to allow consistent reporting. Future research should aim to investigate best approaches for minimising sexual dysfunction.
    Patient summary: Surgical repair of the urethra (urethroplasty) used to treat narrowing of the urethra (urethral stricture) may affect erectile and ejaculatory function. Different questionnaires and definitions are used to evaluate sexual function, so it is hard to compare data. The degree of disruption can be affected by different techniques and the severity of disease.
    MeSH term(s) Male ; Humans
    Language English
    Publishing date 2022-04-13
    Publishing country Netherlands
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2022.03.022
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  7. Article ; Online: What is the Role of Surgery in Bladder Pain Syndrome?

    Downey, Alison P / Osman, Nadir I

    European urology focus

    2019  Volume 5, Issue 3, Page(s) 317–318

    Abstract: The role of surgery in the management of bladder pain syndrome is unclear; particularly the optimum surgical approach. Treatment refractory patients should be managed in a multi-disciplinary setting including psychological support. Further prospective ... ...

    Abstract The role of surgery in the management of bladder pain syndrome is unclear; particularly the optimum surgical approach. Treatment refractory patients should be managed in a multi-disciplinary setting including psychological support. Further prospective studies using validated assessments and clear diagnostic criteria would be useful to guide patient selection.
    MeSH term(s) Combined Modality Therapy ; Cystectomy ; Cystitis, Interstitial/surgery ; Cystitis, Interstitial/therapy ; Humans ; Treatment Outcome
    Language English
    Publishing date 2019-03-20
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2019.03.009
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  8. Article ; Online: A diagnostic conundrum: Is it a periurethral diverticulum/cyst or a bulking agent (Bulkamid)?

    Akinjise-Ferdinand, Oluwaseun / Hubbard, Rachel / Osman, Nadir I / Chapple, Christopher R

    Neurourology and urodynamics

    2022  Volume 42, Issue 2, Page(s) 547–554

    Abstract: Introduction: Urethral bulking agents are commonly used to manage female stress urinary incontinence (SUI) as they have been suggested to be safe, efficacious, and a minimally invasive surgical option. Bulkamid is a newer bulking agent that has been ... ...

    Abstract Introduction: Urethral bulking agents are commonly used to manage female stress urinary incontinence (SUI) as they have been suggested to be safe, efficacious, and a minimally invasive surgical option. Bulkamid is a newer bulking agent that has been introduced and promoted in the market for use. It is non-particulate in nature with high tissue biocompatibility, and consequently, it is difficult to differentiate between Bulkamid and a periurethral cyst on magnetic resonance imaging (MRI). This, therefore, presents a diagnostic dilemma.
    Methods and materials: Here we describe two cases with previous injections of Bulkamid referred to our Centre for management of a presumed periurethral diverticulum based on MRI findings. Both patients were reviewed and examined in outpatient clinics with MRI findings discussed at MDT, further imaging was required.
    Results: We found that a limited noncontrast computed tomography (CT) pelvis, followed by a voiding cystometrogram (VCMG), and then a repeat limited noncontrast CT pelvis effectively differentiated between Bulkamid and these presumed periurethral diverticulae. The theory behind this was that during micturition, the contrast would pass through to the urethral diverticulum and appear as high-density (bright) material within the periurethral region (the pre-VCMG was required to prove that any high-density material was due to the contrast and not pre-existing high-contrast material).
    Conclusion: A CT scan done in conjunction with a VCMG is likely to be more effective in differentiating between Bulkamid and a true periurethral diverticulum than an MRI scan. Appropriate diagnostic evaluation of periurethral lesions can lead to time-saving and cost-effective patient management as this will bypass the need for unnecessary investigations and possible unwarranted surgical intervention.
    MeSH term(s) Humans ; Female ; Urethra/diagnostic imaging ; Urethral Diseases/diagnostic imaging ; Urethral Diseases/therapy ; Urinary Incontinence, Stress/diagnostic imaging ; Urinary Incontinence, Stress/therapy ; Cysts/diagnosis ; Diverticulum/diagnostic imaging ; Diverticulum/therapy
    Chemical Substances Bulkamid
    Language English
    Publishing date 2022-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604904-7
    ISSN 1520-6777 ; 0733-2467
    ISSN (online) 1520-6777
    ISSN 0733-2467
    DOI 10.1002/nau.25068
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    Zs.A 1828: Show issues Location:
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  9. Article ; Online: Tissue engineering: recent advances and review of clinical outcome for urethral strictures.

    Saad, Sanad / Osman, Nadir I / Chapple, Christopher R

    Current opinion in urology

    2021  Volume 31, Issue 5, Page(s) 498–503

    Abstract: Purpose of review: Urethrotomy remains the first-line therapy in the treatment of a urethral stricture despite data showing no real chance of a cure after repeated urethrotomies. An anastomotic or an augmentation urethroplasty using oral mucosa can be ... ...

    Abstract Purpose of review: Urethrotomy remains the first-line therapy in the treatment of a urethral stricture despite data showing no real chance of a cure after repeated urethrotomies. An anastomotic or an augmentation urethroplasty using oral mucosa can be offered to patients following failed urethrotomy. The potential for a tissue engineered solution as an alternative to native tissue has been explored in recent years and is reviewed in this article.
    Recent findings: More than 80 preclinical studies have investigated a tissue-engineered approach for urethral reconstruction mostly using decellularized natural scaffolds derived from natural extracellular matrix with or without cell seeding. The animal models used in preclinical testing are not representative of disease processes seen with strictures in man. The available clinical studies are based on small noncontrolled series.
    Summary: There is a potential role for tissue engineering to provide a material for substitution urethroplasty and work has demonstrated this. Further work will require a rigorous basic science programme and adequate evaluation of the material prior to its introduction into clinical practice. The research with tissue engineering applied to the urethra has not yet been resulted in a widely available material for clinical use that approaches the efficacy seen with the use of autologous grafts.
    MeSH term(s) Animals ; Humans ; Male ; Mouth Mucosa ; Reconstructive Surgical Procedures ; Tissue Engineering ; Urethra/surgery ; Urethral Stricture/surgery
    Language English
    Publishing date 2021-08-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1091792-5
    ISSN 1473-6586 ; 0963-0643
    ISSN (online) 1473-6586
    ISSN 0963-0643
    DOI 10.1097/MOU.0000000000000921
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  10. Article ; Online: Reply to Sanjay B. Kulkarni, Pankaj M. Joshi, Marco Bandini, et al.'s Letter to the Editor re: Sanad Saad, Nadir I. Osman, Christopher R. Chapple. Female Urethra: Is Ventral the True Dorsal? Eur Urol 2020;78:e218-9.

    Saad, Sanad / Osman, Nadir I / Chapple, Christopher R

    European urology

    2021  Volume 81, Issue 1, Page(s) e16–e17

    MeSH term(s) Female ; Humans ; Male ; Multiparametric Magnetic Resonance Imaging ; Urethra ; Urinary Bladder Neoplasms
    Language English
    Publishing date 2021-11-02
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2021.09.032
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