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  1. Article ; Online: The effects of low calorie, high protein diet on body composition, duration and sleep quality on obese adults: A randomized clinical trial.

    Javaheri, Fatemeh Sadat Hashemi / Ostadrahimi, A R / Nematy, Mohsen / Arabi, Seyyed Mostafa / Amini, Mahnaz

    Health science reports

    2023  Volume 6, Issue 11, Page(s) e1699

    Abstract: Background and aims: The effects of high-protein diets on regulating sleep have received research attention in recent decades. However, no studies have examined the effects of these diets in obese adults. Therefore, this study was conducted to ... ...

    Abstract Background and aims: The effects of high-protein diets on regulating sleep have received research attention in recent decades. However, no studies have examined the effects of these diets in obese adults. Therefore, this study was conducted to investigate the effects of low-calorie high protein diets on sleep quality in obese adults.
    Methods: This study is a randomized clinical trial conducted on 60 obese adults (BMI > 29.9 kg/m
    Results: The results showed a significant difference between the control group and intervention group with respect to sleep apnea at 30-, 60-, and 90-day follow-up (
    Conclusion: This study shows that low-calorie high-protein diets can effectively improve apnea, sleep quality, and body composition indices in obese adults.
    Language English
    Publishing date 2023-11-16
    Publishing country United States
    Document type Journal Article
    ISSN 2398-8835
    ISSN (online) 2398-8835
    DOI 10.1002/hsr2.1699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: EFFECT OF PROBIOTIC FERMENTED MILK (KEFIR) ON SERUM LEVEL OF INSULIN AND HOMOCYSTEINE IN TYPE 2 DIABETES PATIENTS.

    Alihosseini, N / Moahboob, S A / Farrin, N / Mobasseri, M / Taghizadeh, A / Ostadrahimi, A R

    Acta endocrinologica (Bucharest, Romania : 2005)

    2019  Volume 13, Issue 4, Page(s) 431–436

    Abstract: Background: Probiotic fermented milk is one of the most beneficial foods. The main purpose of this study was to investigate the effect of probiotic fermented milk on the serum level of insulin and homocysteine in the type 2 diabetes patients.: Methods! ...

    Abstract Background: Probiotic fermented milk is one of the most beneficial foods. The main purpose of this study was to investigate the effect of probiotic fermented milk on the serum level of insulin and homocysteine in the type 2 diabetes patients.
    Methods: This study was done in 60 patients with type 2 diabetes. The intervention group received 600 mL of probiotic fermented milk (kefir) daily and control group received 600 mL of conventional fermented milk daily for 8 weeks. Food intake, anthropometric indices, serum parameters were assessed at the beginning and at the end of the study. The statistical analysis was done by the use of SPSS software (Ver.13).
    Results: The mean of serum insulin level did not reduce significantly after the intervention in probiotic fermented milk group, and there was no significant difference between the two groups. The mean of HOMA-IR decreased significantly in probiotic fermented milk group after intervention and there was a significant difference between the two groups after intervention. The mean of quickie increased in probiotic fermented milk group, but this increase was not significant. Also, there was not significant difference between the two groups after intervention. The mean of homocysteine level decresead significantly in patients with probiotic fermented milk and conventional fermented milk consumption.
    Conclusions: By considering the effect of probiotic fermented milk on some risk factors of cardiovascular disease in diabetic patients, probiotic foods may be useful as an adjuvant therapy in diabetic patients.
    Language English
    Publishing date 2019-05-27
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 1433812-9
    ISSN 1843-066X ; 1841-0987
    ISSN (online) 1843-066X
    ISSN 1841-0987
    DOI 10.4183/aeb.2017.431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A double-blind, placebo-controlled trial related to the effects of melatonin on oxidative stress and inflammatory parameters of obese women.

    Mesri Alamdari, N / Mahdavi, R / Roshanravan, N / Lotfi Yaghin, N / Ostadrahimi, A R / Faramarzi, E

    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

    2015  Volume 47, Issue 7, Page(s) 504–508

    Abstract: Obesity, the global epidemic health problem, results in chronic disorders. Melatonin supplementation may prevent the adverse health consequences of obesity. The aim of this study was to assess the effects of melatonin supplementation on inflammatory and ... ...

    Abstract Obesity, the global epidemic health problem, results in chronic disorders. Melatonin supplementation may prevent the adverse health consequences of obesity. The aim of this study was to assess the effects of melatonin supplementation on inflammatory and oxidative stress parameters in obese women. In randomized, double-blind, placebo-controlled trial, 44 obese women were randomly assigned to melatonin (n=22) and placebo (n=22) groups. Subjects were supplemented with a daily dose of 6 mg melatonin or placebo with low calorie diet for 40 days. Serum TNF-α, IL-6, hsCRP, TAC, and MDA levels were assessed before and after intervention. In the melatonin group, mean serum TNF-α, IL-6, hsCRP, and MDA levels decreased significantly (p<0.05) from 3.52±0.72 pg/ml, 27.12±6.32 pg/ml, 2.54±0.49 mg/l, and 3.81±0.29 nmol/l to 1.73±0.07, 16.34±6.32, 1.67±0.27, and 2.79±0.29, respectively. Whilst in the placebo group the decrease in values were not statistically significant. Mean TAC level increased slightly (from 1.11±0.30 to 1.14±0.45 mmol/l) in the melatonin group whereas it decreased slightly (from 1.13±0.15 to 1.08±0.21 nmol/l) in the placebo group. Significant differences were observed only for TNF-α (p=0.02) and IL-6 (p=0.03) between the 2 study groups. Considering the improvements in inflammatory and oxidative stress factors in obese women, it seems that melatonin supplementation may provide beneficial effects in obesity treatment by ameliorating some of its complications. However, further studies are needed to make concise conclusions.
    MeSH term(s) Adult ; C-Reactive Protein/metabolism ; Double-Blind Method ; Female ; Humans ; Inflammation/blood ; Insulin Resistance/physiology ; Interleukin-6/blood ; Malondialdehyde/blood ; Melatonin/pharmacology ; Obesity/blood ; Oxidative Stress/drug effects ; Treatment Outcome ; Tumor Necrosis Factor-alpha/blood
    Chemical Substances Interleukin-6 ; Tumor Necrosis Factor-alpha ; Malondialdehyde (4Y8F71G49Q) ; C-Reactive Protein (9007-41-4) ; Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2015-06
    Publishing country Germany
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 80125-2
    ISSN 1439-4286 ; 0018-5043
    ISSN (online) 1439-4286
    ISSN 0018-5043
    DOI 10.1055/s-0034-1384587
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A Double-Blind, Placebo-Controlled Trial Related to the Effects of Melatonin on Oxidative Stress and Inflammatory Parameters of Obese Women

    Mesri Alamdari, N. / Mahdavi, R. / Roshanravan, N. / Lotfi Yaghin, N. / Ostadrahimi, A. R. / Faramarzi, E.

    Hormone and Metabolic Research

    2014  Volume 47, Issue 07, Page(s) 504–508

    Abstract: Obesity, the global epidemic health problem, results in chronic disorders. Melatonin supplementation may prevent the adverse health consequences of obesity. The aim of this study was to assess the effects of melatonin supplementation on inflammatory and ... ...

    Abstract Obesity, the global epidemic health problem, results in chronic disorders. Melatonin supplementation may prevent the adverse health consequences of obesity. The aim of this study was to assess the effects of melatonin supplementation on inflammatory and oxidative stress parameters in obese women. In randomized, double-blind, placebo-controlled trial, 44 obese women were randomly assigned to melatonin (n=22) and placebo (n=22) groups. Subjects were supplemented with a daily dose of 6 mg melatonin or placebo with low calorie diet for 40 days. Serum TNF-α, IL-6, hsCRP, TAC, and MDA levels were assessed before and after intervention. In the melatonin group, mean serum TNF-α, IL-6, hsCRP, and MDA levels decreased significantly (p<0.05) from 3.52±0.72 pg/ml, 27.12±6.32 pg/ml, 2.54±0.49 mg/l, and 3.81±0.29 nmol/l to 1.73±0.07, 16.34±6.32, 1.67±0.27, and 2.79±0.29, respectively. Whilst in the placebo group the decrease in values were not statistically significant. Mean TAC level increased slightly (from 1.11±0.30 to 1.14±0.45 mmol/l) in the melatonin group whereas it decreased slightly (from 1.13±0.15 to 1.08±0.21 nmol/l) in the placebo group. Significant differences were observed only for TNF-α (p=0.02) and IL-6 (p=0.03) between the 2 study groups. Considering the improvements in inflammatory and oxidative stress factors in obese women, it seems that melatonin supplementation may provide beneficial effects in obesity treatment by ameliorating some of its complications. However, further studies are needed to make concise conclusions.
    Keywords obesity ; melatonin ; inflammation ; oxidative stress ; low calorie diet
    Language English
    Publishing date 2014-08-15
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80125-2
    ISSN 1439-4286 ; 0018-5043
    ISSN (online) 1439-4286
    ISSN 0018-5043
    DOI 10.1055/s-0034-1384587
    Database Thieme publisher's database

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