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  1. Article ; Online: Retrospective data analysis of animal poisoning events in Liguria.

    Avolio, R / Andreoli, T / Ercolini, C / Mignone, W / Beltrame, R / Razzuoli, E / Modesto, P / Zoppi, S / Crescio, M I / Ostorero, F / Gili, M / Abete, M C / Meloni, D / Dellepiane, M

    Veterinary and animal science

    2021  Volume 13, Page(s) 100178

    Abstract: Intentional poisoning represents a serious risk to domestic and wild animals, and it can be an environmental and human health issue as well . This paper is a retrospective study, which covers a decade, based on animal poisoning cases and poisoned baits ... ...

    Abstract Intentional poisoning represents a serious risk to domestic and wild animals, and it can be an environmental and human health issue as well . This paper is a retrospective study, which covers a decade, based on animal poisoning cases and poisoned baits that were submitted for diagnostic examinations to the Veterinary Medical Research Institute for Piedmont, Liguria and the Aosta Valley (IZS-PLVA) in Liguria region. All data were collected through a passive surveillance system introduced in Italy by a decree of the Ministry of Health in January 2009. 43.2% of the animal poisoning cases were confirmed by toxicological analysis, whereas toxic agents were detected in 31.1% of the baits. The most affected animal species were dogs and cats, followed by synanthropic birds,. Only 4% of the total poisoning events analysed involved wild animals and cases of livestock poisoning were minimal. An increased number of cases in January, March, April and August was noticed, but no seasonal trend was detected. The most affected areas were the ones with the highest level of urbanization and population density. The major cause of the poisonings and the most common substances detected in the examined baits were anticoagulants whereas cholinesterase inhibitors, organochlorine pesticides and carbamates were detected in a minor number of cases. This study raises concerns about deliberate animal poisoning in ligurian region and highlights the necessity to fight this phenomenon as it endangers animals, humans and environment.
    Language English
    Publishing date 2021-05-23
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2451-943X
    ISSN (online) 2451-943X
    DOI 10.1016/j.vas.2021.100178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Abnormal Prothrombin (PIVKA-II) Expression in Canine Tissues as an Indicator of Anticoagulant Poisoning.

    Maniscalco, Lorella / Varello, Katia / Zoppi, Simona / Abbamonte, Giuseppina / Ferrero, Marta / Torres, Elena / Ostorero, Federica / Rossi, Francesca / Bozzetta, Elena

    Animals : an open access journal from MDPI

    2021  Volume 11, Issue 9

    Abstract: PIVKA-II is an aberrant form of vitamin K that has been demonstrated to be increased in human coagulation disorders and in some neoplastic diseases. In veterinary medicine, PIVKA-II levels have been demonstrated to be useful for distinguishing ... ...

    Abstract PIVKA-II is an aberrant form of vitamin K that has been demonstrated to be increased in human coagulation disorders and in some neoplastic diseases. In veterinary medicine, PIVKA-II levels have been demonstrated to be useful for distinguishing anticoagulant poisoning from other coagulopathies. In forensic pathology, there is the need to distinguish malicious poisoning from other causes of death and, in some cases, identifying poisoned dogs from dogs that died as a result of other coagulative disorders can be challenging. In this study, dogs that suddenly died underwent necropsy, histological examination, and toxicological analysis to establish cause of death. PIVKA-II immunohistochemical expression was evaluated on hepatic and renal tissues, and on neoplastic lesions when present. A total of 61 dogs were analyzed and anticoagulant substances were identified in 16 of the 61. Immunolabelling for PIVKA-II was observed in 27 of 61 cases in the liver and in 24 of 61 cases in the kidneys. Among the poisoned dogs, the PIVKA-II expression was present in the liver in 15 of 16 cases and in the kidneys in 16 of 16. Neoplastic lesions represented mainly by haemangiosarcomas were negative. This study highlights how the immunohistochemical expression of PIVKA-II in hepatic and renal tissues can be useful to identify patients with coagulative disorders due to clinical condition or the ingestion of anticoagulants substances.
    Language English
    Publishing date 2021-09-06
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani11092612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Retrospective data analysis of animal poisoning events in Liguria

    Avolio, R / Andreoli, T / Ercolini, C / Mignone, W / Beltrame, R / Razzuoli, E / Modesto, P / Zoppi, S / Crescio, M.I / Ostorero, F / Gili, M / Abete, M.C / Meloni, D / Dellepiane, M

    Veterinary and Animal Science. 2021 Sept., v. 13

    2021  

    Abstract: Intentional poisoning represents a serious risk to domestic and wild animals, and it can be an environmental and human health issue as well . This paper is a retrospective study, which covers a decade, based on animal poisoning cases and poisoned baits ... ...

    Abstract Intentional poisoning represents a serious risk to domestic and wild animals, and it can be an environmental and human health issue as well . This paper is a retrospective study, which covers a decade, based on animal poisoning cases and poisoned baits that were submitted for diagnostic examinations to the Veterinary Medical Research Institute for Piedmont, Liguria and the Aosta Valley (IZS-PLVA) in Liguria region. All data were collected through a passive surveillance system introduced in Italy by a decree of the Ministry of Health in January 2009.43.2% of the animal poisoning cases were confirmed by toxicological analysis, whereas toxic agents were detected in 31.1% of the baits. The most affected animal species were dogs and cats, followed by synanthropic birds,. Only 4% of the total poisoning events analysed involved wild animals and cases of livestock poisoning were minimal. An increased number of cases in January, March, April and August was noticed, but no seasonal trend was detected. The most affected areas were the ones with the highest level of urbanization and population density. The major cause of the poisonings and the most common substances detected in the examined baits were anticoagulants whereas cholinesterase inhibitors, organochlorine pesticides and carbamates were detected in a minor number of cases.This study raises concerns about deliberate animal poisoning in ligurian region and highlights the necessity to fight this phenomenon as it endangers animals, humans and environment.
    Keywords animal science ; biomedical research ; carbamates ; chlorinated hydrocarbons ; cholinesterase ; human health ; livestock ; monitoring ; piedmont ; population density ; research institutions ; retrospective studies ; risk ; synanthropes ; toxicity ; toxicity testing ; urbanization ; Italy
    Language English
    Dates of publication 2021-09
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-AP-2-clean
    ISSN 2451-943X
    DOI 10.1016/j.vas.2021.100178
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Local context and environment as risk factors for acute poisoning in animals in northwest Italy.

    Di Blasio, Alessia / Bertolini, Silvia / Gili, Marilena / Avolio, Rosa / Leogrande, Maria / Ostorero, Federica / Ru, Giuseppe / Dondo, Alessandro / Zoppi, Simona

    The Science of the total environment

    2019  Volume 709, Page(s) 136016

    Abstract: Animal and bait poisoning data for northwest Italy collected between 2012 and 2017 were described and analyzed to estimate the risk of exposure to hazardous substances by animals. In about 4% of animals necropsied (n = 356/9512), the cause of death was ... ...

    Abstract Animal and bait poisoning data for northwest Italy collected between 2012 and 2017 were described and analyzed to estimate the risk of exposure to hazardous substances by animals. In about 4% of animals necropsied (n = 356/9512), the cause of death was poisoning and domestic pets (9.5%) and synanthropic animals (12.2%) appear to be the most involved. Furthermore, 294 out of 728 baits (40.4%) were positive for toxic substances and/or inert hazardous material. Application of a mixed-effects Poisson regression model and local cluster analysis evidenced increased risk of exposure to poisoning with altimetry (>600 m.a.s.l.) and municipality (PR = 1.6, 95%CI 1.2-2.1 for poisoning, PR = 2.2, 95%CI 1.2-4.2 for poisoning by insecticides and PR = 2.9, 95%CI 1.4-6.2 for poisoning by metaldehyde). Since the mountainous areas in the region are mostly devoted to pasture and extensive farming, the high frequency of animal and bait poisoning events may be related to farmers' need to protect their livestock and crops against foxes, wolves, rodents or wild boars. Summarizing, the type of land use and context may influence the frequency and type of toxin chosen to kill animals considered a nuisance for hunting, farming, agriculture and apiculture. Despite bans and limitations, the use of harmful substances is not perceived as an environmental threat but rather as routine pest control. Animal and bait poisoning constitute a public health concern because it is potentially harmful to humans and the environment. Our findings may inform risk communication strategies, as well as prevention and control measures for the reduction of illegal and non-targeted species poisoning.
    MeSH term(s) Agriculture ; Animals ; Insecticides/analysis ; Italy ; Poisons ; Risk Factors
    Chemical Substances Insecticides ; Poisons
    Language English
    Publishing date 2019-12-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2019.136016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Article: [No title information]

    Gili, Marilena / Prearo, Marino / Stella, Paola / Ostorero, Federica / Abete, Maria Cesarina

    Italian journal of food safety

    2014  Volume 3, Issue 1, Page(s) 1640

    Title translation Multiresidue Screening Method for Detection of Benzimidazoles and their Metabolites in Liver and Muscle by High-Performance Liquid Chromatography: Method Development and Validation According to Commission Decision 2002/657/EC.
    Language Italian
    Publishing date 2014-02-06
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2717109-7
    ISSN 2239-7132
    ISSN 2239-7132
    DOI 10.4081/ijfs.2014.1640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: LC-MS/MS Identification of Species-Specific Muscle Peptides in Processed Animal Proteins.

    Marchis, Daniela / Altomare, Alessandra / Gili, Marilena / Ostorero, Federica / Khadjavi, Amina / Corona, Cristiano / Ru, Giuseppe / Cappelletti, Benedetta / Gianelli, Silvia / Amadeo, Francesca / Rumio, Cristiano / Carini, Marina / Aldini, Giancarlo / Casalone, Cristina

    Journal of agricultural and food chemistry

    2017  

    Abstract: An innovative analytical strategy has been applied to identify signature peptides able to distinguish among processed animal proteins (PAPs) derived from bovine, pig, fish, and milk products. Proteomics was first used to elucidate the proteome of each ... ...

    Abstract An innovative analytical strategy has been applied to identify signature peptides able to distinguish among processed animal proteins (PAPs) derived from bovine, pig, fish, and milk products. Proteomics was first used to elucidate the proteome of each source. Starting from the identified proteins and using a funnel based approach, a set of abundant and well characterized peptides with suitable physical-chemical properties (signature peptides) and specific for each source was selected. An on-target LC-ESI-MS/MS method (MRM mode) was set up using standard peptides and was then applied to selectively identify the PAP source and also to distinguish proteins from bovine carcass and milk proteins. We believe that the method described meets the request of the European Commission which has developed a strategy for gradually lifting the "total ban" toward "species to species ban", therefore requiring official methods for species-specific discrimination in feed.
    Language English
    Publishing date 2017-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.7b04639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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