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Article ; Online: Capacity and use of diagnostics and treatment for patients with severe acute respiratory infections in the pre-COVID-19 era in district and provincial hospitals in Viet Nam.

Dat, Vu Quoc / Giang, Kim Bao / Vu, Hieu Quang / Otsu, Satoko

Western Pacific surveillance and response journal : WPSAR

2021 Volume 12, Issue 4, Page(s) 1–9

Abstract: Objective: To describe the burden of severe acute respiratory infection (SARI) and the infrastructure and current practices of SARI management in hospitals in Viet Nam.: Methods: We conducted a short observational study at critical care units (CCUs) ... ...

Abstract	Objective: To describe the burden of severe acute respiratory infection (SARI) and the infrastructure and current practices of SARI management in hospitals in Viet Nam. Methods: We conducted a short observational study at critical care units (CCUs) in 32 district hospitals and 16 provincial hospitals in five provinces in Viet Nam from March to July 2019. We collected data on hospital equipment and medicines used in SARI management. At the patient level, data were collected for 14 consecutive days on all patients presenting to CCUs, including information on demographics, intervention and treatment within 24 hours of CCU admission and 7-day outcome. Results: There were significant differences between district and provincial hospitals in the availability of microbial culture, rapid influenza diagnostic tests, inflammatory markers and mechanical ventilation. Among 1722 eligible patients admitted to CCUs, there were 395 (22.9%) patients with SARI. The median age of SARI patients was 74 (interquartile range: 58-84) years; 49.1% were male. Although systemic antibiotics were available in all hospitals and were empirically given to 93.4% of patients, oseltamivir was available in 25% of hospitals, and only 0.5% of patients received empiric oseltamivir within 24 hours of admission. The 7-day mortality was 6.6% (26/395). Independent factors associated with 7-day mortality were septic shock and requiring respiratory support within 24 hours of admission. Discussion: SARI is a major burden on CCUs in Viet Nam. Barriers to delivering quality care include the limited availability of diagnostics and medication and non-protocolized management of SARI in CCUs.
MeSH term(s)	Aged ; Aged, 80 and over ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/therapy ; Hospitals ; Humans ; Influenza, Human/diagnosis ; Influenza, Human/drug therapy ; Influenza, Human/epidemiology ; Male ; Middle Aged ; SARS-CoV-2 ; Vietnam/epidemiology
Language	English
Publishing date	2021-11-30
Publishing country	Philippines
Document type	Journal Article ; Observational Study
ZDB-ID	2592503-9
ISSN	2094-7313 ; 2094-7313
ISSN (online)	2094-7313
ISSN	2094-7313
DOI	10.5365/wpsar.2021.12.4.835
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: External validation of a clinical prediction rule on the need for radiologic imaging to identify urological disorders in adult patients with febrile urinary tract infections.

Kobayashi, Ken-Ichiro / Yamashita, Korei / Mizuno, Shinsuke / Kubo, Kenji / Komiya, Nobuhiro / Otsu, Satoko

Singapore medical journal

2022 Volume 63, Issue 3, Page(s) 167–169

MeSH term(s)	Adult ; Clinical Decision Rules ; Female ; Fever ; Humans ; Male ; Urinary Tract Infections/diagnosis ; Urinary Tract Infections/diagnostic imaging
Language	English
Publishing date	2022-05-14
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	604319-7
ISSN	0037-5675
ISSN	0037-5675
DOI	10.11622/smedj.2022047
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Article ; Online: Antibiotic use for empirical therapy in the critical care units in primary and secondary hospitals in Vietnam: a multicenter cross-sectional study.

Dat, Vu Quoc / Dat, Tran Tat / Hieu, Vu Quang / Giang, Kim Bao / Otsu, Satoko

The Lancet regional health. Western Pacific

2021 Volume 18, Page(s) 100306

Abstract: Background: The high rate of infections among patients admitted to critical care units (CCUs) is associated with high rate of antibiotic consumption, especially broad-spectrum antibiotics. This study is to describe the antibiotics use in CCUs in primary ...

Abstract	Background: The high rate of infections among patients admitted to critical care units (CCUs) is associated with high rate of antibiotic consumption, especially broad-spectrum antibiotics. This study is to describe the antibiotics use in CCUs in primary and secondary hospitals in Vietnam, a setting with high burden of antibiotic resistance. Methods: This was a 7-day observational study in 51 CCUs in hospitals from 5 provinces in Vietnam from March to July 2019. Patients aged ≥ 18 years admitted to the participating CCUs was enrolled consecutively. We collected data on patient's demographics, initial diagnosis and antibiotic therapy within the first 24 hours. Antibiotic therapy was classified by the Anatomical Therapeutic Chemical (ATC) Index and the 2019 WHO Access, Watch, Reserve (AWaRe) groups. Findings: Out of 1747 enrolled patients, empirical antibiotic treatments were initiated in 1112 (63.6%) patients. The most frequently prescribed antibiotics were cefotaxime (22.3%), levofloxacin (19%) and ceftazidime (10.8%). Antibiotics were given in 31.5% of patients without diagnosis of infection. Watch and/or Reserve group antibiotic were given in 87.3% of patients and associated with patient's age (aOR 1.01 per 1-year increment, 95%CI 1.00-1.02) and the presence of SIRS on admission (aOR 2.1, 95%CI 1.38-3.2). Interpretation: We observed a high frequency use and a substantial variation in patterns of empirical antibiotic use in the CCUs in Vietnam. It highlights the importance of continuous monitoring antibiotic consumption in CCUs.
Language	English
Publishing date	2021-11-03
Publishing country	England
Document type	Journal Article
ISSN	2666-6065
ISSN (online)	2666-6065
DOI	10.1016/j.lanwpc.2021.100306
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Article: [A Case Diagnosed Toxocariasis After the Intiation of Treatment with Steroids for Eosinophilic Granulomatosis with Polyangitis (EGPA)].

Komiya, Nobuhiro / Kubo, Kenji / Ohmune, Kouhei / Otsu, Satoko

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases

2018 Volume 90, Issue 6, Page(s) 825–828

MeSH term(s)	Electromyography ; Female ; Granulomatosis with Polyangiitis/drug therapy ; Humans ; Middle Aged ; Steroids/therapeutic use ; Toxocariasis/diagnostic imaging ; Toxocariasis/drug therapy
Chemical Substances	Steroids
Language	Japanese
Publishing date	2018-10-02
Publishing country	Japan
Document type	Case Reports ; Journal Article
ZDB-ID	605664-7
ISSN	0387-5911
ISSN	0387-5911
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Article ; Online: Clinical Characteristics of Patients With Coronavirus Disease 2019 in Japan: A Single-Center Case Series.

Kobayashi, Ken-Ichiro / Kaki, Takahiro / Mizuno, Shinsuke / Kubo, Kenji / Komiya, Nobuhiro / Otsu, Satoko

The Journal of infectious diseases

2020 Volume 222, Issue 2, Page(s) 194–197

Abstract: We report a case series of 6 patients with confirmed coronavirus disease 2019 (COVID-19) in Wakayama prefecture, Japan. All 6 of the patients tested positive via pharyngeal swab polymerase chain reaction (PCR) tests, and 2 of the 6 were still positive at ...

Abstract	We report a case series of 6 patients with confirmed coronavirus disease 2019 (COVID-19) in Wakayama prefecture, Japan. All 6 of the patients tested positive via pharyngeal swab polymerase chain reaction (PCR) tests, and 2 of the 6 were still positive at 3 weeks after onset. All of the patients exhibited bilateral ground glass opacities on computed tomography (CT). This article also reports narrative information on the spectrum of symptoms collected directly from the patients. It would be difficult to triage patients with COVID-19 based on the typical symptoms of fever and/or cough, although PCR and CT are definitive in diagnosis.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/physiopathology ; Cough ; Female ; Fever ; Humans ; Japan ; Lung/diagnostic imaging ; Male ; Middle Aged ; Pandemics ; Pharynx/virology ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/physiopathology ; Polymerase Chain Reaction ; SARS-CoV-2 ; Tomography, X-Ray Computed
Keywords	covid19
Language	English
Publishing date	2020-05-07
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	3019-3
ISSN	1537-6613 ; 0022-1899
ISSN (online)	1537-6613
ISSN	0022-1899
DOI	10.1093/infdis/jiaa244
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Zs.MO 445: Show issues

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Article ; Online: How Ho Chi Minh City adapted its care pathway to manage the first large-scale community transmission of COVID-19.

Khue, Luong Ngoc / Khoa, Nguyen Trong / Duong, Vuong Anh / Hien, Do Thi Hong / Otsu, Satoko / Quang, Phung Kim / Ayana, Dereje Abera / Takaya, Saho / Sobel, Howard L / Hieu, Vu Quang

Western Pacific surveillance and response journal : WPSAR

2023 Volume 14, Issue 5 Spec edition, Page(s) 1–4

MeSH term(s)	Humans ; COVID-19/epidemiology ; Critical Pathways ; Vietnam/epidemiology ; Pandemics
Language	English
Publishing date	2023-09-30
Publishing country	Philippines
Document type	Journal Article
ZDB-ID	2592503-9
ISSN	2094-7313 ; 2094-7313
ISSN (online)	2094-7313
ISSN	2094-7313
DOI	10.5365/wpsar.2023.14.5.1045
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Article ; Online: Cephalic tetanus as a differential diagnosis of facial nerve palsy.

Kotani, Yuki / Kubo, Kenji / Otsu, Satoko / Tsujimoto, Toshihide

BMJ case reports

2017 Volume 2017

Abstract: Cephalic tetanus is defined as a combination of trismus and paralysis of one or more cranial nerves. Since it is a rare cause of facial nerve palsy, it is often overlooked as a differential diagnosis. We present the case of a 75-year-old man admitted to ... ...

Abstract	Cephalic tetanus is defined as a combination of trismus and paralysis of one or more cranial nerves. Since it is a rare cause of facial nerve palsy, it is often overlooked as a differential diagnosis. We present the case of a 75-year-old man admitted to our emergency department with left facial nerve palsy, left ptosis and dysphagia 2 weeks after a head laceration. Soon after admission, he was orally intubated because of massive aspiration. A delayed diagnosis of cephalic tetanus was reached only when he was extubated and trismus and risus sardonicus were identified in addition to facial nerve palsy. The patient was re-intubated and successfully extubated on day 20 postadmission. In orally intubated patients, trismus and risus sardonicus may be overlooked, and although rare, cephalic tetanus should be considered to be a differential diagnosis of facial nerve palsy.
MeSH term(s)	Accidental Falls ; Aged ; Delayed Diagnosis ; Diagnosis, Differential ; Encephalitis/diagnosis ; Facial Nerve Diseases/diagnosis ; Facial Nerve Diseases/etiology ; Facial Paralysis/diagnosis ; Facial Paralysis/etiology ; Humans ; Lacerations ; Male ; Meningitis/diagnosis ; Scalp/injuries ; Stroke/diagnosis ; Tetanus/complications ; Tetanus/diagnosis ; Trismus/diagnosis ; Trismus/etiology
Language	English
Publishing date	2017-01-20
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2016-216440
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Article: Erysipelothrix rhusiopathiae

Kobayashi, Ken-Ichiro / Kawano, Tomoaki / Mizuno, Shinsuke / Kubo, Kenji / Komiya, Nobuhiro / Otsu, Satoko

IDCases

2019 Volume 18, Page(s) e00631

Abstract: Erysipelothrix ... ...

Abstract	Erysipelothrix rhusiopathiae
Language	English
Publishing date	2019-08-29
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2745454-X
ISSN	2214-2509
ISSN	2214-2509
DOI	10.1016/j.idcr.2019.e00631
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Article ; Online: Prevalence of hepatitis B and C virus infections in hemodialysis patients in Vietnam: A systematic review and meta-analysis.

Duong, Minh C / Nguyen, Van T T / Otsu, Satoko / McLaws, Mary-Louise

JGH open : an open access journal of gastroenterology and hepatology

2019 Volume 4, Issue 1, Page(s) 29–38

Abstract: Background and aim: Chronic hemodialysis patients are at high risk of contracting hepatitis B (HBV) and C (HCV) virus infections. In Vietnam, the seroprevalence of HBV and HCV infections is approximately 10 and 4%, respectively. Although the chronic ... ...

Abstract	Background and aim: Chronic hemodialysis patients are at high risk of contracting hepatitis B (HBV) and C (HCV) virus infections. In Vietnam, the seroprevalence of HBV and HCV infections is approximately 10 and 4%, respectively. Although the chronic hemodialysis population is increasing, relatively little epidemiology is available for HBV and HCV infections in this population. To address this, we reviewed the current literature on the magnitude of these infections in the hemodialysis population in Vietnam. Methods: Four databases were used to search for publications containing the prevalence of HBV and/or HCV infections in hemodialysis patients in Vietnam. Grey literature search was utilized to identify local publications. Prevalence and 95% confidence interval were used or calculated, and a meta-analysis was conducted on HBV and HCV prevalence for comparison. Results: Sixteen studies were included in the review. The search identified knowledge gaps in the current literature. Available data show that HBV and HCV infections remain prevalent in the hemodialysis population. HBV prevalence is not different between the north and the south of Vietnam. The pattern of HCV prevalence is different, with recent reports of lower prevalence in the south than in the north, while HCV prevalence varies between hemodialysis units in the same regions. Conclusions: A national prevalence survey of hemodialysis patients would improve the reliability and generalizability of the findings. However, the review confirmed that both HBV and HCV were prevalent in hemodialysis patients. The findings support a reinforcement of infection prevention to minimize the risk of HBV and HCV transmission in hemodialysis facilities.
Language	English
Publishing date	2019-06-17
Publishing country	Australia
Document type	Journal Article
ISSN	2397-9070
ISSN (online)	2397-9070
DOI	10.1002/jgh3.12199
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Article: PIPDeploy: Development and implementation of a gamified table top simulation exercise to strengthen national pandemic vaccine preparedness and readiness

Ghiga, Ioana / Richardson, Sol / Álvarez, Alba Maria Ropero / Kato, Masaya / Naidoo, Dhamari / Otsu, Satoko / Nguyen, Phuc Thi / Nguyen, Phuong Nam / Nguyen, Tim

Vaccine. 2021 Jan. 08, v. 39, no. 2

2021

Abstract: Successful emergency vaccination campaigns rely on effective deployment and vaccination plans. This applies to localised outbreaks as well as for pandemics. In the wake of the 2009 H1N1 influenza pandemic, analysis of the global Vaccine Deployment ... ...

Abstract	Successful emergency vaccination campaigns rely on effective deployment and vaccination plans. This applies to localised outbreaks as well as for pandemics. In the wake of the 2009 H1N1 influenza pandemic, analysis of the global Vaccine Deployment Initiative, through which the World Health Organization (WHO) donated pandemic influenza vaccines to countries in need, revealed that an absence of vaccine deployment plans in many countries significantly hindered vaccine deployment. Through the Pandemic Influenza Preparedness Framework adopted by the World Health Assembly in 2011, WHO is engaging in several capacity building activities to improve pandemic influenza preparedness and response and make provisions for access to vaccines and sharing of other benefits. The Framework calls for the development and exercise of operational plans for deployment of influenza vaccines to enhance pandemic preparedness. To this end, WHO has supported the development of PIPDeploy, an interactive, in-person table top simulation exercise to facilitate learning for emergency preparedness. It employs various game design elements including a game board, time pressure, leaderboards and teams to enhance participants’ motivation. PIPDeploy formed part of five WHO Pandemic Influenza Vaccine Deployment Workshops attended by national-level managers responsible for pandemic influenza vaccine response predominantly in non-producing countries. The purpose of this study was to describe the features and application of PIPDeploy, and present findings of the evaluation of participants’ experiences during the simulation involving a “hot wash” discussion and collection of quantitative data. The simulation’s instructional approach was widely accepted by participants, who reported that the format was novel and engaging. They reflected on its utility for identifying gaps in their own vaccine deployment plans and regulatory frameworks for importation of vaccine products. All participants found the simulation relevant to their professional objectives. A range of other potential applications were suggested, including PIPDeploy’s adaptation to sub-national contexts and to other epidemic diseases.
Keywords	World Health Organization ; disaster preparedness ; exercise ; influenza ; influenza vaccines ; motivation ; pandemic ; vaccination
Language	English
Dates of publication	2021-0108
Size	p. 364-371.
Publishing place	Elsevier Ltd
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2020.11.047
Database	NAL-Catalogue (AGRICOLA)

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