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  1. AU="Otsuka, Junji"
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  1. Book ; Online: Self-Supervised Reversed Image Signal Processing via Reference-Guided Dynamic Parameter Selection

    Otsuka, Junji / Yoshimura, Masakazu / Ohashi, Takeshi

    2023  

    Abstract: Unprocessed sensor outputs (RAW images) potentially improve both low-level and high-level computer vision algorithms, but the lack of large-scale RAW image datasets is a barrier to research. Thus, reversed Image Signal Processing (ISP) which converts ... ...

    Abstract Unprocessed sensor outputs (RAW images) potentially improve both low-level and high-level computer vision algorithms, but the lack of large-scale RAW image datasets is a barrier to research. Thus, reversed Image Signal Processing (ISP) which converts existing RGB images into RAW images has been studied. However, most existing methods require camera-specific metadata or paired RGB and RAW images to model the conversion, and they are not always available. In addition, there are issues in handling diverse ISPs and recovering global illumination. To tackle these limitations, we propose a self-supervised reversed ISP method that does not require metadata and paired images. The proposed method converts a RGB image into a RAW-like image taken in the same environment with the same sensor as a reference RAW image by dynamically selecting parameters of the reversed ISP pipeline based on the reference RAW image. The parameter selection is trained via pseudo paired data created from unpaired RGB and RAW images. We show that the proposed method is able to learn various reversed ISPs with comparable accuracy to other state-of-the-art supervised methods and convert unknown RGB images from COCO and Flickr1M to target RAW-like images more accurately in terms of pixel distribution. We also demonstrate that our generated RAW images improve performance on real RAW image object detection task.

    Comment: 19 pages, 12 figures
    Keywords Computer Science - Computer Vision and Pattern Recognition ; Electrical Engineering and Systems Science - Image and Video Processing
    Subject code 006
    Publishing date 2023-03-24
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: A Case of Pneumocystis Pneumonia Developed During Rheumatoid Arthritis Treatment With Methotrexate and Golimumab.

    Yanagihara, Toyoshi / Oka, Yusuke / Moriwaki, Atushi / Moriuchi, Yuki / Ogata, Hiroaki / Ishimatsu, Akiko / Otsuka, Junji / Taguchi, Kazuhito / Yoshida, Makoto

    Cureus

    2024  Volume 16, Issue 1, Page(s) e52944

    Abstract: Here, we report a case of an 87-year-old female patient with rheumatoid arthritis (RA) treated with methotrexate (MTX) and golimumab who developed severe pneumocystis pneumonia (PCP), also known ... ...

    Abstract Here, we report a case of an 87-year-old female patient with rheumatoid arthritis (RA) treated with methotrexate (MTX) and golimumab who developed severe pneumocystis pneumonia (PCP), also known as
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52944
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Acute Exacerbation of Idiopathic Pulmonary Fibrosis With Concurrent Cardiac Amyloidosis: A Technetium Pyrophosphate Study.

    Yanagihara, Toyoshi / Hatashima, Hikaru / Ogata, Hiroaki / Moriuchi, Yuki / Ishimatsu, Akiko / Otsuka, Junji / Taguchi, Kazuhito / Moriwaki, Atushi / Yoshida, Makoto

    Cureus

    2024  Volume 16, Issue 3, Page(s) e56358

    Abstract: Amyloidosis presents a diagnostic challenge, particularly when concomitant with severe conditions like acute exacerbations of idiopathic pulmonary fibrosis (IPF). In this report, we detail the case of a 73-year-old patient with acute exacerbation of IPF ... ...

    Abstract Amyloidosis presents a diagnostic challenge, particularly when concomitant with severe conditions like acute exacerbations of idiopathic pulmonary fibrosis (IPF). In this report, we detail the case of a 73-year-old patient with acute exacerbation of IPF and simultaneous emergence of cardiac amyloidosis. The patient's clinical journey began with persistent exertional dyspnea, progressing to hypoxemia on admission. Chest CT scans showed extensive ground-glass opacities, consolidations, and pre-existing honeycombing-like cysts and reticular shadows, accompanied by a right-sided pleural effusion. The therapeutic strategy for acute exacerbation of IPF encompassed methylprednisolone pulse therapy, tacrolimus, and nintedanib, augmented with intravenous immunoglobulin and recombinant thrombomodulin. Concurrently, heart failure with preserved ejection fraction was managed with a pharmacological trio: empagliflozin, diuretics, and eplerenone. A hypertrophied heart and low limb voltage prompted an investigation for cardiac amyloidosis, which
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.56358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Amikacin Liposome Inhalation Suspension in the Real-World Management of Refractory Mycobacterium avium Complex Pulmonary Disease.

    Yanagihara, Toyoshi / Ogata, Hiroaki / Mori, Asami / Kadowaki, Masako / Moriuchi, Yuki / Ishimatsu, Akiko / Otsuka, Junji / Taguchi, Kazuhito / Moriwaki, Atushi / Yoshida, Makoto

    Cureus

    2024  Volume 16, Issue 3, Page(s) e56622

    Abstract: The increasing prevalence ... ...

    Abstract The increasing prevalence of
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.56622
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  5. Book ; Online: Rawgment

    Yoshimura, Masakazu / Otsuka, Junji / Irie, Atsushi / Ohashi, Takeshi

    Noise-Accounted RAW Augmentation Enables Recognition in a Wide Variety of Environments

    2022  

    Abstract: Image recognition models that work in challenging environments (e.g., extremely dark, blurry, or high dynamic range conditions) must be useful. However, creating training datasets for such environments is expensive and hard due to the difficulties of ... ...

    Abstract Image recognition models that work in challenging environments (e.g., extremely dark, blurry, or high dynamic range conditions) must be useful. However, creating training datasets for such environments is expensive and hard due to the difficulties of data collection and annotation. It is desirable if we could get a robust model without the need for hard-to-obtain datasets. One simple approach is to apply data augmentation such as color jitter and blur to standard RGB (sRGB) images in simple scenes. Unfortunately, this approach struggles to yield realistic images in terms of pixel intensity and noise distribution due to not considering the non-linearity of Image Signal Processors (ISPs) and noise characteristics of image sensors. Instead, we propose a noise-accounted RAW image augmentation method. In essence, color jitter and blur augmentation are applied to a RAW image before applying non-linear ISP, resulting in realistic intensity. Furthermore, we introduce a noise amount alignment method that calibrates the domain gap in the noise property caused by the augmentation. We show that our proposed noise-accounted RAW augmentation method doubles the image recognition accuracy in challenging environments only with simple training data.

    Comment: Accepted to CVPR2023
    Keywords Computer Science - Computer Vision and Pattern Recognition ; Electrical Engineering and Systems Science - Image and Video Processing
    Subject code 006
    Publishing date 2022-10-28
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Book ; Online: DynamicISP

    Yoshimura, Masakazu / Otsuka, Junji / Irie, Atsushi / Ohashi, Takeshi

    Dynamically Controlled Image Signal Processor for Image Recognition

    2022  

    Abstract: Image Signal Processors (ISPs) play important roles in image recognition tasks as well as in the perceptual quality of captured images. In most cases, experts make a lot of effort to manually tune many parameters of ISPs, but the parameters are sub- ... ...

    Abstract Image Signal Processors (ISPs) play important roles in image recognition tasks as well as in the perceptual quality of captured images. In most cases, experts make a lot of effort to manually tune many parameters of ISPs, but the parameters are sub-optimal. In the literature, two types of techniques have been actively studied: a machine learning-based parameter tuning technique and a DNN-based ISP technique. The former is lightweight but lacks expressive power. The latter has expressive power, but the computational cost is too heavy on edge devices. To solve these problems, we propose "DynamicISP," which consists of multiple classical ISP functions and dynamically controls the parameters of each frame according to the recognition result of the previous frame. We show our method successfully controls the parameters of multiple ISP functions and achieves state-of-the-art accuracy with low computational cost in single and multi-category object detection tasks.

    Comment: Accepted to ICCV2023. Several updates from v2 including additional experiments and modification of typos in Auto Gain equation
    Keywords Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Artificial Intelligence ; Electrical Engineering and Systems Science - Systems and Control
    Subject code 006
    Publishing date 2022-11-02
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Acute Pneumonitis Associated With the Inhalation of Pyrethroid-Based Domestic Insecticides.

    Yanagihara, Toyoshi / Nakagawa, Takuya / Fukushima, Takehito / Moriuchi, Yuki / Ogata, Hiroaki / Ishimatsu, Akiko / Otsuka, Junji / Kadowaki, Masako / Moriwaki, Atushi / Yoshida, Makoto

    Cureus

    2023  Volume 15, Issue 8, Page(s) e43200

    Abstract: We report a 72-year-old female who presented to our hospital with a worsening cough and dyspnea that had emerged a week earlier following the accidental inhalation of a significant quantity of spray-type imiprothrin (a synthetic pyrethroid)-based ... ...

    Abstract We report a 72-year-old female who presented to our hospital with a worsening cough and dyspnea that had emerged a week earlier following the accidental inhalation of a significant quantity of spray-type imiprothrin (a synthetic pyrethroid)-based insecticide in her bathroom. She exhibited acute respiratory failure necessitating 4 L/minute of nasal oxygen at maximum. Chest CT images showed diffuse centrilobular ground-glass opacities with mosaic attenuation and consolidation areas in the lower lobes of both lungs. The patient was diagnosed with acute pneumonitis due to insecticide inhalation, and her symptoms improved following methylprednisolone pulse and alpha-tocopherol therapy. Generally, the accidental inhalation of aerosolized pyrethroids does not induce significant respiratory symptoms, and case reports on pulmonary toxicity related to pyrethroid inhalation are scarce. This case report underscores the need to include inhaled pyrethroid insecticides in the differential diagnosis of patients with acute pneumonitis and suggests that methylprednisolone and alpha-tocopherol therapy can be beneficial for treating this condition.
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.43200
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  8. Article: A Teaching Case: Persistent COVID-19 Pneumonia Resembling Cryptogenic Organizing Pneumonia in a Patient With Remitted Lymphoma.

    Yanagihara, Toyoshi / Kadowaki, Masako / Otsuka, Junji / Ishimatsu, Akiko / Taguchi, Kazuhito / Moriuchi, Yuki / Ogata, Hiroaki / Moriwaki, Atushi / Yoshida, Makoto

    Cureus

    2023  Volume 15, Issue 11, Page(s) e48319

    Abstract: We report a case of a female patient in her 50s, previously diagnosed with follicular lymphoma (now in complete remission), who was admitted to our hospital due to antibiotic-resistant pneumonia lasting a month. The patient had contracted coronavirus ... ...

    Abstract We report a case of a female patient in her 50s, previously diagnosed with follicular lymphoma (now in complete remission), who was admitted to our hospital due to antibiotic-resistant pneumonia lasting a month. The patient had contracted coronavirus disease 2019 (COVID-19) pneumonia a year earlier and exhibited persistent hypogammaglobulinemia. Chest CT scans revealed wondering ground-glass opacities and consolidations initially suggestive of cryptogenic organizing pneumonia (COP). Despite repeatedly negative nasopharyngeal SARS-CoV-2 tests, the virus was detected in the bronchoalveolar lavage fluid (BALF) using the BioFire FilmArray Respiratory Panel 2.1. She was subsequently diagnosed with COVID-19 pneumonia and responded well to treatment with remdesivir (RDV) and intravenous immunoglobulin. The SARS-CoV-2 variant in the BALF was suspected as the Omicron variant (XBB.1.16), prevalent in the area at the admission, indicating a re-infection rather than a recurrence. This case underscores the protracted nature of COVID-19 pneumonia in immunocompromised patients and the risks of false negatives in nasopharyngeal SARS-CoV-2 tests. Direct SARS-CoV-2 measurement from BALF can be crucial in such cases. A COP diagnosis based solely on imaging and administering corticosteroids without antiviral treatment might exacerbate the situation by reactivating SARS-CoV-2. Given the current pandemic, clinicians should be aware of the potential for persistent or recurrent COVID-19, particularly in immunocompromised patients.
    Language English
    Publishing date 2023-11-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.48319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Clinical features of relapsed connective tissue disease-associated organizing pneumonia.

    Otsuka, Junji / Yoshizawa, Shigeru / Kudo, Kunihiro / Osoreda, Hisayuki / Ishimatsu, Akiko / Taguchi, Kazuhito / Moriwaki, Atsushi / Wakamatsu, Kentaro / Iwanaga, Tomoaki / Yoshida, Makoto

    Respiratory medicine

    2023  Volume 219, Page(s) 107419

    Abstract: Background: Organizing pneumonia (OP) is recognized as a nonspecific lung injury response characterized histopathologically by the presence of intra-alveolar buds of granulation tissue. Most OP patients show excellent responses to corticosteroids, but ... ...

    Abstract Background: Organizing pneumonia (OP) is recognized as a nonspecific lung injury response characterized histopathologically by the presence of intra-alveolar buds of granulation tissue. Most OP patients show excellent responses to corticosteroids, but relapse is frequently seen when corticosteroids are tapered or discontinued. Although several factors associated with relapse have been reported in cryptogenic OP (COP), the clinical features and risk factors associated with relapse in connective tissue disease-associated OP (CTD-OP) have yet to be fully understood.
    Methods: We retrospectively reviewed data on 47 CTD-OP patients. We investigated the frequency of relapse and compared the clinical data between CTD-OP with and without relapse to clarify the risk factors for relapse.
    Results: Eleven (23.4%) CTD-OP patients had relapses of OP during the study. In the multivariate analysis, no CTD treatment at OP diagnosis [O.R. 11.920, p = 0.012] and partial remission after steroid treatment [O.R. 35.944, p = 0.045] were independent risk factors for relapse. Among rheumatoid arthritis-associated OP (RA-OP) patients, partial remission after steroid treatment [O.R. 16.151, p = 0.047] and age at OP diagnosis [O.R. 0.899, p = 0.045] were independent risk factors for relapse. Most of the relapsed OP patients who were on no medication at OP diagnosis later developed CTD.
    Conclusion: CTD-OP patients with residual disease on HRCT after treatment and who had OP diagnosis preceding CTD diagnosis were more likely to have an OP relapse. During the clinical course of relapsed OP patients, it is necessary to pay attention to the onset of CTD.
    MeSH term(s) Humans ; Retrospective Studies ; Organizing Pneumonia ; Pneumonia/drug therapy ; Cryptogenic Organizing Pneumonia/diagnosis ; Cryptogenic Organizing Pneumonia/diagnostic imaging ; Connective Tissue Diseases/complications ; Adrenal Cortex Hormones/therapeutic use ; Recurrence ; Steroids/therapeutic use
    Chemical Substances Adrenal Cortex Hormones ; Steroids
    Language English
    Publishing date 2023-10-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1003348-8
    ISSN 1532-3064 ; 0954-6111
    ISSN (online) 1532-3064
    ISSN 0954-6111
    DOI 10.1016/j.rmed.2023.107419
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  10. Article: Relapsing eosinophilic pneumonia in a patient with recurrent breast cancer receiving abemaciclib plus endocrine therapy.

    Ogata, Hiroaki / Koga, Chinami / Yanagihara, Toyoshi / Moriuchi, Yuki / Enokizu-Ogawa, Aimi / Ishimatsu, Akiko / Otsuka, Junji / Taguchi, Kazuhito / Moriwaki, Atsushi / Tokunaga, Eriko / Yoshida, Makoto

    Respirology case reports

    2024  Volume 12, Issue 3, Page(s) e01320

    Abstract: This report presents the case of a 42-year-old Japanese woman with recurrent hormone receptor-positive breast cancer who developed eosinophilic pneumonia (EP) during treatment with abemaciclib combined with endocrine therapy. Seven years after a radical ... ...

    Abstract This report presents the case of a 42-year-old Japanese woman with recurrent hormone receptor-positive breast cancer who developed eosinophilic pneumonia (EP) during treatment with abemaciclib combined with endocrine therapy. Seven years after a radical surgery and definite diagnosis of Stage I breast cancer, her cancer recurred with metastases to multiple organs. Initially treated with abemaciclib plus letrozole and goserelin for 3 months, she developed EP, which improved after the discontinuation of anti-cancer treatment and the administration of prednisolone. However, EP occurred again upon the reintroduction of endocrine therapy (i.e., letrozole and goserelin). It improved gradually with the suspension of endocrine therapy and the re-administration of prednisolone. This case underscores the need for further research into the prevention and management of EP in patients receiving abemaciclib with endocrine therapy for advanced breast cancer.
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2750180-2
    ISSN 2051-3380
    ISSN 2051-3380
    DOI 10.1002/rcr2.1320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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