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  1. Article ; Online: Delayed diagnosed injuries in trauma patients after initial trauma assessment with a total-body computed tomography scan.

    Kok, D / Oud, S / Giannakópoulos, G F / Scheerder, M J / Beenen, L F M / Halm, J A / Treskes, K

    Injury

    2023  Volume 55, Issue 5, Page(s) 111304

    Abstract: Introduction: Even when using the Advanced Trauma Life Support (ATLS) guidelines and other diagnostic protocols for the initial assessment of trauma patients, not all injuries will be diagnosed in this early stage of care. The aim of this study was to ... ...

    Abstract Introduction: Even when using the Advanced Trauma Life Support (ATLS) guidelines and other diagnostic protocols for the initial assessment of trauma patients, not all injuries will be diagnosed in this early stage of care. The aim of this study was to quantify how many, and assess which type of injuries were diagnosed with delay during the initial assessment of trauma patients including a total-body computed tomography (TBCT) scan in a Level 1 Trauma Center in the Netherlands.
    Methods: We conducted a retrospective cohort study of 697 trauma patients who were assessed in the trauma bay of the Amsterdam University Medical Center (AUMC), using a TBCT. A delayed diagnosed injury was defined as an injury sustained during the initial trauma and not discovered nor suspected upon admission to the Intensive Care Unit (ICU) or surgical ward following the initial assessment, diagnostic studies, or during immediate surgery. A clinically significant delayed diagnosis of injury was defined as an injury requiring follow-up or further medical treatment. We aimed to identify variables associated with delayed diagnosed injuries.
    Results: In total, 697 trauma patients with a median age of 46 years (IQR 30-61) and a median Injury Severity Score (ISS) of 16 (IQR 9-25) were included. Delayed diagnosed injuries were found in 97 patients (13.9 %), of whom 79 injuries were clinically significant (81.4 %). Forty-eight of the delayed diagnosed injuries (49.5 %) were within the TBCT field. Ten delayed diagnosed injuries had an Abbreviated Injury Scale (AIS) of ≥3. Most injuries were diagnosed before or during the tertiary survey (60.8 %). The median time of delay was 34.5 h (IQR 17.5-157.3). Variables associated with delayed diagnosed injuries were primary ICU admission (OR 1.8, p = 0.014), an ISS ≥ 16 (OR 1.6, p = 0.042), and prolonged hospitalization (40+ days) (OR 8.5, p < 0.001).
    Conclusion: With the inclusion of the TBCT during the primary assessment of trauma patients, delayed diagnosed injuries still occurs in a significant number of patients (13.9 %). Factors associated with delayed diagnosed injuries were direct admission to ICU and an ISS ≥ 16.
    MeSH term(s) Humans ; Adult ; Middle Aged ; Retrospective Studies ; Injury Severity Score ; Trauma Centers ; Intensive Care Units ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-12-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2023.111304
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: The Effects of the Environment and Linear Actuators on Robot Morphologies

    Oud, Steven / van der Pool, Koen

    2022  

    Abstract: The field of evolutionary robotics uses principles of natural evolution to design robots. In this paper, we study the effect of adding a new module inspired by the skeletal muscle to the existing RoboGen framework: the linear actuator. Additionally, we ... ...

    Abstract The field of evolutionary robotics uses principles of natural evolution to design robots. In this paper, we study the effect of adding a new module inspired by the skeletal muscle to the existing RoboGen framework: the linear actuator. Additionally, we investigate how robots evolved in a plain environment differ from robots evolved in a rough environment. We consider the task of directed locomotion for comparing evolved robot morphologies. The results show that the addition of the linear actuator does not have a significant impact on the performance and morphologies of robots evolved in a plain environment. However, we find significant differences in the morphologies of robots evolved in a plain environment and robots evolved in a rough environment. We find that more complex behavior and morphologies emerge when we change the terrain of the environment.
    Keywords Computer Science - Robotics ; Computer Science - Neural and Evolutionary Computing
    Subject code 629
    Publishing date 2022-04-02
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Shockwavelike Behavior across Social Media.

    Manrique, Pedro D / Huo, Frank Yingjie / El Oud, Sara / Zheng, Minzhang / Illari, Lucia / Johnson, Neil F

    Physical review letters

    2023  Volume 130, Issue 23, Page(s) 237401

    Abstract: Online communities featuring "anti-X" hate and extremism, somehow thrive online despite moderator pressure. We present a first-principles theory of their dynamics, which accounts for the fact that the online population comprises diverse individuals and ... ...

    Abstract Online communities featuring "anti-X" hate and extremism, somehow thrive online despite moderator pressure. We present a first-principles theory of their dynamics, which accounts for the fact that the online population comprises diverse individuals and evolves in time. The resulting equation represents a novel generalization of nonlinear fluid physics and explains the observed behavior across scales. Its shockwavelike solutions explain how, why, and when such activity rises from "out-of-nowhere," and show how it can be delayed, reshaped, and even prevented by adjusting the online collective chemistry. This theory and findings should also be applicable to anti-X activity in next-generation ecosystems featuring blockchain platforms and Metaverses.
    MeSH term(s) Humans ; Social Media ; Ecosystem ; Hate
    Language English
    Publishing date 2023-06-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.130.237401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Pelvic Ring Fractures in Older Adult Patients-Assessing Physician Practice Variation among (Orthopedic) Trauma Surgeons.

    Mennen, Anna H M / Oud, Sharon / Halm, Jens A / Peters, Rolf W / Willems, Hanna C / Van Embden, Daphne

    Journal of clinical medicine

    2023  Volume 12, Issue 19

    Abstract: Purpose: Pelvic fractures in older adults are a major public health problem and socioeconomic burden. The standard of care has changed over the past years, and there is limited consensus on which patients benefit from surgical fixation. There is ... ...

    Abstract Purpose: Pelvic fractures in older adults are a major public health problem and socioeconomic burden. The standard of care has changed over the past years, and there is limited consensus on which patients benefit from surgical fixation. There is currently no nationwide treatment protocol to guide the decision-making process. Therefore, the aim of this survey was to provide more insight into if, when, and why patients with a fragility fracture of the pelvis (FFPs) would be considered for additional imaging and surgical fixation by treating physicians.
    Methods: An online clinical vignette-based survey of hypothetical scenarios was sent out to all orthopedic and trauma surgeons in the Netherlands. The questionnaire comprised multiple-choice questions and radiographic images. Differences between subgroups were calculated using the X2 test or the Fisher exact test.
    Results: 169 surgeons responded to the survey, with varying levels of experience and working in different types of hospitals. In a patient with a simple pubic ramus fracture and ASA 2 or ASA 4, 32% and 18% of the respondents would always advise a CT scan for further analysis. In the same patients, 11% and 31% of the respondents would not advise a CT scan, respectively. When presented with three cases of increasing severity of co-morbidity (ASA) and/or increasing age and/or different clinical presentation of an FFP type 3c on a CT scan, an increasing number of respondents would not consider surgical fixation. There was significant variation in practice patterns between the respondents who do not work in a hospital performing pelvic and acetabular (P&A) fracture surgery and those who do work in a P&A referral hospital. Most respondents (77%) refer patients 1-5 times a year to an expert center for surgical fixation.
    Conclusion: There is currently a wide variety of clinical practices regarding the imaging and management of FFPs, which seems to be influenced by the type of hospital the patients are presented to. A regional or national evidence-based treatment protocol should be implemented to ensure a more uniform approach.
    Language English
    Publishing date 2023-10-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12196344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Supporting the medial hinge in proximal humerus fractures with an intramedullary plate.

    Gardenbroek, Tjibbe J / Oud, Sharon / Formijne Jonkers, Henk A / Goslings, J Carel

    Trauma case reports

    2021  Volume 33, Page(s) 100474

    Abstract: Proximal humerus fractures are common and approximately 20% of displaced fractures may benefit from surgery. A lack of medial support is found to be a predictor of failure after surgical fixation of proximal humerus fractures. The optimal technique for ... ...

    Abstract Proximal humerus fractures are common and approximately 20% of displaced fractures may benefit from surgery. A lack of medial support is found to be a predictor of failure after surgical fixation of proximal humerus fractures. The optimal technique for restoring the medial hinge is unclear. We describe two cases of patients with a dislocated 4-part humerus fracture treated with a locking plate and an additional small intramedullary plate to support the medial hinge. This technique is simple and allows for an enhanced stability of the medial hinge during and after surgery.
    Language English
    Publishing date 2021-04-21
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2835433-3
    ISSN 2352-6440 ; 2352-6440
    ISSN (online) 2352-6440
    ISSN 2352-6440
    DOI 10.1016/j.tcr.2021.100474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Analyzing the heart rhythm during chest compressions: Performance and clinical value of a new AED algorithm.

    de Graaf, Corina / Beesems, Stefanie G / Oud, Sharon / Stickney, Ronald E / Piraino, Daniel W / Chapman, Fred W / Koster, Rudolph W

    Resuscitation

    2021  Volume 162, Page(s) 320–328

    Abstract: Purpose: Automated external defibrillators (AED) prompt the rescuer to stop chest compressions (CC) for ECG analysis during out-of-hospital cardiac arrest (OHCA). We assessed the diagnostic accuracy and clinical benefit of a new AED algorithm ( ... ...

    Abstract Purpose: Automated external defibrillators (AED) prompt the rescuer to stop chest compressions (CC) for ECG analysis during out-of-hospital cardiac arrest (OHCA). We assessed the diagnostic accuracy and clinical benefit of a new AED algorithm (cprINSIGHT), which analyzes ECG and impedance signals during CC, allowing rhythm analysis with ongoing chest compressions.
    Methods: Amsterdam Police and Fire Fighters used a conventional AED in 2016-2017 (control) and an AED with cprINSIGHT in 2018-2019 (intervention). In the intervention AED, cprINSIGHT was activated after the first (conventional) analysis. This algorithm classified the rhythm as "shockable" (S) and "non-shockable" (NS), or "pause needed". Sensitivity for S, specificity for NS with 90% lower confidence limit (LCL), chest compression fractions (CCF) and pre-shock pause were compared between control and intervention cases accounting for multiple observations per patient.
    Results: Data from 465 control and 425 intervention cases were analyzed. cprINSIGHT reached a decision during CC in 70% of analyses. Sensitivity of the intervention AED was 96%, (LCL 93%) and specificity was 98% (LCL 97%), both not significantly different from control. Intervention cases had a shorter median pre-shock pause compared to control cases (8 s vs 22 s, p < 0.001) and higher median CCF (86% vs 80%, P < 0.001).
    Conclusion: AEDs with cprINSIGHT analyzed the ECG during chest compressions in 70% of analyses with 96% sensitivity and 98% specificity when it made a S or a NS decision. Compared to conventional AEDs, cprINSIGHT leads to a significantly shorter pre-shock pause and a significant increase in CCF.
    MeSH term(s) Algorithms ; Cardiopulmonary Resuscitation ; Defibrillators ; Electric Countershock ; Electrocardiography ; Humans ; Out-of-Hospital Cardiac Arrest/therapy
    Language English
    Publishing date 2021-01-16
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2021.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Effect of phosphogypsum application and bacteria co-inoculation on biochemical properties and nutrient availability to maize plants in a saline soil

    Al-Enazy, Abdul-Aziz / Al-Barakah, Fahad / Al-Oud, Saud / Usman, Adel

    Archives of agronomy and soil science

    2018  Volume 64, Issue 8/14, Page(s) 1394

    Language English
    Document type Article
    ZDB-ID 1132910-5
    ISSN 0365-0340
    Database Current Contents Nutrition, Environment, Agriculture

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  8. Article ; Online: The online competition between pro- and anti-vaccination views.

    Johnson, Neil F / Velásquez, Nicolas / Restrepo, Nicholas Johnson / Leahy, Rhys / Gabriel, Nicholas / El Oud, Sara / Zheng, Minzhang / Manrique, Pedro / Wuchty, Stefan / Lupu, Yonatan

    Nature

    2020  Volume 582, Issue 7811, Page(s) 230–233

    Abstract: Distrust in scientific ... ...

    Abstract Distrust in scientific expertise
    MeSH term(s) Algorithms ; COVID-19 ; COVID-19 Vaccines ; Cluster Analysis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/psychology ; Humans ; Internationality ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Public Opinion ; Social Media/statistics & numerical data ; Time Factors ; Vaccination/psychology ; Viral Vaccines
    Chemical Substances COVID-19 Vaccines ; Viral Vaccines
    Keywords covid19
    Language English
    Publishing date 2020-05-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-020-2281-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The online competition between pro- and anti-vaccination views

    Johnson, Neil F / Velásquez, Nicolas / Restrepo, Nicholas Johnson / Leahy, Rhys / Gabriel, Nicholas / El Oud, Sara / Zheng, Minzhang / Manrique, Pedro / Wuchty, Stefan / Lupu, Yonatan

    Nature

    Abstract: Distrust in scientific expertise1-14 is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks2-4, as happened for measles in 20195,6. Homemade remedies7,8 and ... ...

    Abstract Distrust in scientific expertise1-14 is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks2-4, as happened for measles in 20195,6. Homemade remedies7,8 and falsehoods are being shared widely on the Internet, as well as dismissals of expert advice9-11. There is a lack of understanding about how this distrust evolves at the system level13,14. Here we provide a map of the contention surrounding vaccines that has emerged from the global pool of around three billion Facebook users. Its core reveals a multi-sided landscape of unprecedented intricacy that involves nearly 100 million individuals partitioned into highly dynamic, interconnected clusters across cities, countries, continents and languages. Although smaller in overall size, anti-vaccination clusters manage to become highly entangled with undecided clusters in the main online network, whereas pro-vaccination clusters are more peripheral. Our theoretical framework reproduces the recent explosive growth in anti-vaccination views, and predicts that these views will dominate in a decade. Insights provided by this framework can inform new policies and approaches to interrupt this shift to negative views. Our results challenge the conventional thinking about undecided individuals in issues of contention surrounding health, shed light on other issues of contention such as climate change11, and highlight the key role of network cluster dynamics in multi-species ecologies15.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #307789
    Database COVID19

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  10. Article ; Online: The online competition between pro- and anti-vaccination views

    Johnson, Neil F. / Velásquez, Nicolas / Restrepo, Nicholas Johnson / Leahy, Rhys / Gabriel, Nicholas / El Oud, Sara / Zheng, Minzhang / Manrique, Pedro / Wuchty, Stefan / Lupu, Yonatan

    reponame:Expeditio Repositorio Institucional UJTL ; instname:Universidad de Bogotá Jorge Tadeo Lozano

    2020  

    Abstract: Distrust in scientific expertise1,2,3,4,5,6,7,8,9,10,11,12,13,14 is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks2,3,4, as happened for measles in 20195,6. ...

    Abstract Distrust in scientific expertise1,2,3,4,5,6,7,8,9,10,11,12,13,14 is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks2,3,4, as happened for measles in 20195,6. Homemade remedies7,8 and falsehoods are being shared widely on the Internet, as well as dismissals of expert advice9,10,11. There is a lack of understanding about how this distrust evolves at the system level13,14. Here we provide a map of the contention surrounding vaccines that has emerged from the global pool of around three billion Facebook users. Its core reveals a multi-sided landscape of unprecedented intricacy that involves nearly 100 million individuals partitioned into highly dynamic, interconnected clusters across cities, countries, continents and languages. Although smaller in overall size, anti-vaccination clusters manage to become highly entangled with undecided clusters in the main online network, whereas pro-vaccination clusters are more peripheral. Our theoretical framework reproduces the recent explosive growth in anti-vaccination views, and predicts that these views will dominate in a decade. Insights provided by this framework can inform new policies and approaches to interrupt this shift to negative views. Our results challenge the conventional thinking about undecided individuals in issues of contention surrounding health, shed light on other issues of contention such as climate change11, and highlight the key role of network cluster dynamics in multi-species ecologies15.
    Keywords Vacunación ; Síndrome respiratorio agudo grave ; COVID-19 ; SARS-CoV-2 ; Coronavirus ; Anti-vaccination views ; covid19
    Publishing date 2020-05-13
    Publisher Science Direct
    Publishing country co
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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