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Article ; Online: First-in-Man Experience of Robotic-Assisted Transcatheter Edge-to-Edge Repair With Pure Echo Guidance.

Zhu, Da / Wang, Shouzheng / Ouyang, Wenbin / Pan, Xiangbin

2024

Language	English
Publishing date	2024-04-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2024.03.022
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Zs.A 6669: Show issues

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Article: Transcatheter aortic valve replacement in patients with preoperative ascending aortic diameter ≥45 mm.

An, Kang / Zhang, Fengwen / Ouyang, Wenbin / Pan, Xiangbin

Cardiovascular diagnosis and therapy

2023 Volume 13, Issue 6, Page(s) 939–947

Abstract: Background: Current indication for concomitant replacement of ascending aorta (AA) in patients undergoing surgical aortic valve replacement is that AA diameter exceeds 45 mm. However, the impact of AA dilation (≥45 mm) in patients undergoing ... ...

Abstract	Background: Current indication for concomitant replacement of ascending aorta (AA) in patients undergoing surgical aortic valve replacement is that AA diameter exceeds 45 mm. However, the impact of AA dilation (≥45 mm) in patients undergoing transcatheter aortic valve replacement (TAVR) remains unclear. Methods: We retrospectively evaluated 467 consecutive patients who underwent transfemoral TAVR from January 2016 to April 2021. Cox proportional hazards regression was performed to identify risk factors for all-cause mortality. The primary endpoint was the all-cause mortality, and the secondary endpoints were the occurrence of the aortic dissection and/or rupture. Results: One hundred patients (21.4%) presented preoperative AA ≥45 mm. The median age was 73 years for patients with AA ≥45 mm and 75 years for patients with AA <45 mm (P=0.021). The in-hospital mortality rate was 1.1%. There was no iatrogenic injury to the AA. Only one patient (0.2%) in AA <45 mm group experienced retrograde type B aortic dissection in the descending aorta. The median follow-up was 19 [16-34] months in patients with AA ≥45 mm and 27 [15-37] months in patients with AA <45 mm (P=0.152). No statistical difference was found between the two groups regarding the overall survival (92.5%±3.5% Conclusions: Transfemoral TAVR can be performed safely in patients with preoperative AA ≥45 mm with a low intraprocedural risk. The mid-term survival appears not to be affected by the presence of AA ≥45 mm, and adverse aortic events are rare.
Language	English
Publishing date	2023-12-08
Publishing country	China
Document type	Journal Article
ZDB-ID	2685043-6
ISSN	2223-3660 ; 2223-3652
ISSN (online)	2223-3660
ISSN	2223-3652
DOI	10.21037/cdt-23-324
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Article: Comparison of self- and balloon-expandable valves in patients with dilatated ascending aorta undergoing transcatheter aortic valve replacement.

An, Kang / Zhang, Fengwen / Ouyang, Wenbin / Pan, Xiangbin

Journal of thoracic disease

2023 Volume 15, Issue 9, Page(s) 4826–4835

Abstract: Background: Limited studies have focused on the performance of self-expandable valves (SEVs) and balloon-expandable valves (BEVs) in patients with dilatated ascending aorta (AA) undergoing transcatheter aortic valve replacement (TAVR). The present study ...

Abstract	Background: Limited studies have focused on the performance of self-expandable valves (SEVs) and balloon-expandable valves (BEVs) in patients with dilatated ascending aorta (AA) undergoing transcatheter aortic valve replacement (TAVR). The present study compared the performance of widely used Edwards BEVs and domestic SEVs in patients with dilatated AA among Chinese population. Methods: We identified and reviewed 207 patients who had baseline AA diameter ≥40 mm and underwent transfemoral TAVR. Patients were divided into two groups: SEV and BEV. The SEVs were locally manufactured valves that have received Chinese regulatory approval (Venus-A, Taurus One, and VitaFlow), while the BEVs were Edwards Sapien XT and Sapien3. Procedural device success and post-procedural changes of AA diameters were compared. Results: The sample size of SEV group was larger than that of BEV group because BEVs were not available in China in the early clinical practice. The overall device success was slightly lower in SEV group compared with BEV group (84.2% Conclusions: In patients with dilatated AA who underwent TAVR, the type of THVs did not affect the procedural device success. BAV appeared to be a risk factor for both device failure and higher aortic expansion rate in these patients.
Language	English
Publishing date	2023-08-30
Publishing country	China
Document type	Journal Article
ZDB-ID	2573571-8
ISSN	2077-6624 ; 2072-1439
ISSN (online)	2077-6624
ISSN	2072-1439
DOI	10.21037/jtd-23-364
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Article ; Online: Prevalence of mental stress and its association with witnessing cyberbullying and coping strategies among undergraduates in Hunan, China in 2021.

Tang, Bei / Ouyang, Wenbin / Deng, Jing / Huang, Xin

Technology and health care : official journal of the European Society for Engineering and Medicine

2023 Volume 32, Issue 2, Page(s) 915–924

Abstract: Background: In the wave of the novel coronavirus (COVID-19) epidemic, there is a need to investigate the mental health status of Chinese university students.: Objective: To examine the effects of witnessing cyberbullying on psychological distress and ...

Abstract	Background: In the wave of the novel coronavirus (COVID-19) epidemic, there is a need to investigate the mental health status of Chinese university students. Objective: To examine the effects of witnessing cyberbullying on psychological distress and the mediating role of coping on these effects in Chinese university students, which is yet to be examined. Methods: 306 Chinese university students were enrolled in this cross-sectional study. Linear regression was conducted to analyze the relationship between depression, anxiety and being a bystander to cyberbullying, whereas the bootstrapping approach tested the mediation effects of coping strategies. Results: Results indicated that 27.12% of subjects (95% CI: 22.22%, 32.48%) suffered from anxiety and 44.12% (95% CI: 38.47%, 49.88%) were depressed. Meanwhile, 89.87% of subjects were involved in witnessing cyberbullying. Being a bystander to cyberbullying was weakly but significantly associated with anxiety (β= 0.195, 95% CI: 0.068, 0.292) and depression (β= 0.223, 95% CI: 0.113,0.333). Negative coping partially mediated between witnessing cyberbullying and anxiety, with mediation effect values of 0.04 (P< 0.05). While being a bystander to cyberbullying was only directly associated with depression. Conclusion: Based on our findings, college students in Hunan, China, are experiencing anxiety, depression and cyberbullying after COVID-19. Being a bystander to cyberbullying is associated with coping strategies, anxiety, and depression. Cyberbullying has a direct impact on anxiety, but it also influences anxiety through mediating effects on coping.
MeSH term(s)	Humans ; Cyberbullying/psychology ; Coping Skills ; Adaptation, Psychological ; Cross-Sectional Studies ; Prevalence ; Anxiety/epidemiology ; Students/psychology ; COVID-19/epidemiology ; China/epidemiology ; Depression/epidemiology
Language	English
Publishing date	2023-08-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1159961-3
ISSN	1878-7401 ; 0928-7329
ISSN (online)	1878-7401
ISSN	0928-7329
DOI	10.3233/THC-230305
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Zs.A 3846: Show issues

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Book ; Online: TLMCM Network for Medical Image Hierarchical Multi-Label Classification

Wu, Meng / Luo, Siyan / Wu, Qiyu / Ouyang, Wenbin

2023

Abstract: Medical Image Hierarchical Multi-Label Classification (MI-HMC) is of paramount importance in modern healthcare, presenting two significant challenges: data imbalance and \textit{hierarchy constraint}. Existing solutions involve complex model architecture ...

Abstract	Medical Image Hierarchical Multi-Label Classification (MI-HMC) is of paramount importance in modern healthcare, presenting two significant challenges: data imbalance and \textit{hierarchy constraint}. Existing solutions involve complex model architecture design or domain-specific preprocessing, demanding considerable expertise or effort in implementation. To address these limitations, this paper proposes Transfer Learning with Maximum Constraint Module (TLMCM) network for the MI-HMC task. The TLMCM network offers a novel approach to overcome the aforementioned challenges, outperforming existing methods based on the Area Under the Average Precision and Recall Curve($AU\overline{(PRC)}$) metric. In addition, this research proposes two novel accuracy metrics, $EMR$ and $HammingAccuracy$, which have not been extensively explored in the context of the MI-HMC task. Experimental results demonstrate that the TLMCM network achieves high multi-label prediction accuracy($80\%$-$90\%$) for MI-HMC tasks, making it a valuable contribution to healthcare domain applications.
Keywords	Computer Science - Computer Vision and Pattern Recognition
Subject code	006
Publishing date	2023-11-01
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: The structural stability and polarization analysis of rhombohedral phase HfO2

Ouyang, Wenbin / Jia, Fanghao / Ren, Wei

2023

Abstract: A comparative theoretical study is presented for the rhombohedral R3 and R3m phase HfO2, of two possible forms in its heavily Zr-doped ferroelectric thin films found recently in experiments. Their structural stability and polarization under the in-plane ... ...

Abstract	A comparative theoretical study is presented for the rhombohedral R3 and R3m phase HfO2, of two possible forms in its heavily Zr-doped ferroelectric thin films found recently in experiments. Their structural stability and polarization under the in-plane compressive strain are comprehensively investigated. We discovered that there is a phase transition from R3 to R3m phase under the biaxial compressive strain. Both the direction and amplitude of their polarization can be tuned by the strain. By performing a symmetry mode analysis, we are able to understand its improper nature of the ferroelectricity. These results may help to shed light on the understanding of the hafnia ferroelectric thin films.
Keywords	Condensed Matter - Materials Science
Publishing date	2023-06-09
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Global, regional, and national time trends in disability-adjusted life years, mortality, and variable risk factors of non-rheumatic calcified aortic valve disease, 1990-2019: an age-period-cohort analysis of the Global Burden of Disease 2019 study.

Liu, Zeye / Su, Zhanhao / Li, Wenchao / Zhang, Fengwen / Ouyang, Wenbin / Wang, Shouzheng / Pan, Xiangbin

Journal of thoracic disease

2023 Volume 15, Issue 4, Page(s) 2079–2097

Abstract: Background: Non-rheumatic heart valve disease (NRVD) is a common cardiovascular disease, whereas calcific aortic valve disease (CAVD) is a type of disease with the fastest-growing mortality and disability-adjusted life years (DALYs). This study presents ...

Abstract	Background: Non-rheumatic heart valve disease (NRVD) is a common cardiovascular disease, whereas calcific aortic valve disease (CAVD) is a type of disease with the fastest-growing mortality and disability-adjusted life years (DALYs). This study presents an overview of the trends noted in the DALY, CAVD mortality, and the modiﬁable risk factors in the last 30 years, across 204 countries and territories, and their relationship with the period, age, and birth cohort. Methods: Data were obtained from the Global Burden of Disease (GBD) 2019 database. An age-period-cohort (APC) model was used to assess general annual percentage changes in DALYs and mortality over the past 30 years in 204 countries and territories. Results: In 2019, the age-standardized mortality rate for the entire population in areas with a high socio-demographic index (SDI) was more than 4 times higher than that in low-SDI areas. From 1990 to 2019, the net drift in mortality for the whole population was from -2.1% [95% confidence interval (CI): -2.39% to -1.82%] per year in high-SDI regions to 0.05% (95% CI: -0.13% to 0.23%) per year in low- to medium-SDI regions. The trend of DALYs was similar to that of mortality. The age-wise distribution of deaths exhibited a shift toward older populations in high-SDI regions globally, except for Qatar, Saudi Arabia, and the United Arab Emirates. Over time, in most medium, medium-low, and low SDI regions, there was no significant improvement in the period and birth cohort or even an unfavorable or worsening risk. The main variable risk factors of CAVD death and DALYs lost were high sodium diet, high systolic blood pressure, and lead exposure. Those risk factors only showed a significant downward trend in middle- and high-SDI regions. Conclusions: Health disparities between regions for CAVD are widening and could lead to a heavy disease burden in the future. Health authorities and policymakers in low SDI areas, in particular, need to consider improving resource allocation, increasing access to medical resources, and controlling variable risk factors to stem the growth of the disease burden.
Language	English
Publishing date	2023-04-25
Publishing country	China
Document type	Journal Article
ZDB-ID	2573571-8
ISSN	2077-6624 ; 2072-1439
ISSN (online)	2077-6624
ISSN	2072-1439
DOI	10.21037/jtd-23-480
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Corrigendum to 'Alerting trends in epidemiology for non-rheumatic degenerative mitral valve disease, 1990-2019: An age-period-cohort analysis for the Global Burden of Disease Study 2019' [Int. J. Cardiol. 395(2024) 131561].

Liu, Zeye / Wei, Peijian / Jiang, Hong / Zhang, Fengwen / Ouyang, Wenbin / Wang, Shouzheng / Fang, Fang / Pan, Xiangbin

International journal of cardiology

2024 Volume 403, Page(s) 131919

Language	English
Publishing date	2024-03-02
Publishing country	Netherlands
Document type	Published Erratum
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2024.131919
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Zs.A 1673: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Book ; Online: Learning to Configure Separators in Branch-and-Cut

Li, Sirui / Ouyang, Wenbin / Paulus, Max B. / Wu, Cathy

2023

Abstract: Cutting planes are crucial in solving mixed integer linear programs (MILP) as they facilitate bound improvements on the optimal solution. Modern MILP solvers rely on a variety of separators to generate a diverse set of cutting planes by invoking the ... ...

Abstract	Cutting planes are crucial in solving mixed integer linear programs (MILP) as they facilitate bound improvements on the optimal solution. Modern MILP solvers rely on a variety of separators to generate a diverse set of cutting planes by invoking the separators frequently during the solving process. This work identifies that MILP solvers can be drastically accelerated by appropriately selecting separators to activate. As the combinatorial separator selection space imposes challenges for machine learning, we learn to separate by proposing a novel data-driven strategy to restrict the selection space and a learning-guided algorithm on the restricted space. Our method predicts instance-aware separator configurations which can dynamically adapt during the solve, effectively accelerating the open source MILP solver SCIP by improving the relative solve time up to 72% and 37% on synthetic and real-world MILP benchmarks. Our work complements recent work on learning to select cutting planes and highlights the importance of separator management.
Keywords	Mathematics - Optimization and Control ; Computer Science - Machine Learning
Subject code	670
Publishing date	2023-11-07
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Bioinformatic analysis of potential biomarkers and mechanisms of immune infiltration in mitral regurgitation complicated by atrial fibrillation.

Li, Zefu / Kong, Pengxu / Wen, Bin / Wang, Shouzheng / Zhang, Fengwen / Ouyang, Wenbin / Pan, Xiangbin

Annals of translational medicine

2022 Volume 10, Issue 21, Page(s) 1174

Abstract: Background: Mitral regurgitation (MR) is one of the most prevalent valvular diseases. Degenerated MR-induced volume overload leads to left atrial enlargement and eventually, atrial fibrillation (AF). AF has a negative effect on patient prognosis despite ...

Abstract	Background: Mitral regurgitation (MR) is one of the most prevalent valvular diseases. Degenerated MR-induced volume overload leads to left atrial enlargement and eventually, atrial fibrillation (AF). AF has a negative effect on patient prognosis despite recent advances in minimal invasive transcatheter devices for valve surgery. However, more effective strategies aimed at precisely treating from pathophysiology and genetic perspective are scarce. Methods: The gene expression datasets, GSE109744 and GSE79768, were obtained from the Gene Expression Omnibus database and analyzed to identify the differentially expressed genes (DEGs) in patients with mitral value prolapse (MVP) and AF. Subsequently, we predicted the extensive miRNA targets, and the protein-protein interaction (PPI) and miRNA-target gene regulatory networks were established. Functional enrichment analyses were performed for the DEGs. In addition, the co-expressed DEGs coupled with their predicted miRNAs and disease phenotypes involved in MVP and AF were assessed. Finally, the immune infiltration in both datasets was examined. Results: A total of 491 and 180 DEGs were identified in the mitral valve and left atrial specimens, respectively. From these, 11 integrated co-expressed DEGs were identified, namely, Conclusions: MR and AF are related, and 11 co-expressed DEGs were found to be significantly associated with MVP with AF, and indeed, these may represent novel biomarkers. Several immune cells were found to contribute to the process of MVP and AF via diverse mechanisms, in particular, antigen-presenting cells.
Language	English
Publishing date	2022-11-27
Publishing country	China
Document type	Journal Article
ZDB-ID	2893931-1
ISSN	2305-5847 ; 2305-5839
ISSN (online)	2305-5847
ISSN	2305-5839
DOI	10.21037/atm-22-4595
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