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  1. AU="Oyim, James"
  2. AU="Fu, Yuntian"
  3. AU="Spigland, N"
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Artikel: Photodynamic Antimicrobial Chemotherapy: Advancements in Porphyrin-Based Photosensitize Development.

Oyim, James / Omolo, Calvin A / Amuhaya, Edith K

Frontiers in chemistry

2021  Band 9, Seite(n) 635344

Abstract: The reduction of available drugs with effectiveness against microbes is worsening with the current global crisis of antimicrobial resistance. This calls for innovative strategies for combating antimicrobial resistance. Photodynamic Antimicrobial ... ...

Abstract The reduction of available drugs with effectiveness against microbes is worsening with the current global crisis of antimicrobial resistance. This calls for innovative strategies for combating antimicrobial resistance. Photodynamic Antimicrobial Chemotherapy (PACT) is a relatively new method that utilizes the combined action of light, oxygen, and a photosensitizer to bring about the destruction of microorganisms. This technique has been found to be effective against a wide spectrum of microorganisms, including bacteria, viruses, and fungi. Of greater interest is their ability to destroy resistant strains of microorganisms and in effect help in combating the emergence of antimicrobial resistance. This manuscript reviews porphyrins and porphyrin-type photosensitizers that have been studied in the recent past with a focus on their structure-activity relationship.
Sprache Englisch
Erscheinungsdatum 2021-04-07
Erscheinungsland Switzerland
Dokumenttyp Journal Article ; Review
ZDB-ID 2711776-5
ISSN 2296-2646
ISSN 2296-2646
DOI 10.3389/fchem.2021.635344
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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