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  1. Article ; Online: What is an appropriate strategy of conversion surgery for cT4b thoracic esophageal cancer?

    Ozawa, Soji

    Annals of gastroenterological surgery

    2021  Volume 5, Issue 2, Page(s) 130–131

    Language English
    Publishing date 2021-04-09
    Publishing country Japan
    Document type Editorial
    ISSN 2475-0328
    ISSN (online) 2475-0328
    DOI 10.1002/ags3.12453
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Minimally Invasive Surgery for Esophageal Cancer in Japan.

    Ozawa, Soji

    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia

    2020  Volume 26, Issue 4, Page(s) 179–183

    MeSH term(s) Diffusion of Innovation ; Esophageal Neoplasms/history ; Esophageal Neoplasms/surgery ; Esophagectomy/adverse effects ; Esophagectomy/history ; History, 20th Century ; History, 21st Century ; Humans ; Japan ; Mediastinoscopy/adverse effects ; Mediastinoscopy/history ; Patient Positioning ; Prone Position ; Robotic Surgical Procedures/adverse effects ; Robotic Surgical Procedures/history ; Thoracoscopy/adverse effects ; Thoracoscopy/history ; Treatment Outcome
    Language English
    Publishing date 2020-08-01
    Publishing country Japan
    Document type Editorial ; Historical Article ; Review
    ZDB-ID 2019756-1
    ISSN 2186-1005 ; 1341-1098
    ISSN (online) 2186-1005
    ISSN 1341-1098
    DOI 10.5761/atcs.ed.20-00079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5253: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  3. Article ; Online: Is sentinel node mapping useful for esophageal cancer surgery?

    Ozawa, Soji

    Annals of gastroenterological surgery

    2019  Volume 3, Issue 1, Page(s) 5–6

    Language English
    Publishing date 2019-01-15
    Publishing country Japan
    Document type Editorial
    ISSN 2475-0328
    ISSN (online) 2475-0328
    DOI 10.1002/ags3.12231
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  4. Article ; Online: Detrimental impact of late-onset pneumonia on long-term prognosis in oesophageal cancer survivors.

    Takiguchi, Hiroto / Koyanagi, Kazuo / Ozawa, Soji / Oguma, Tsuyoshi / Asano, Koichiro

    Respiratory investigation

    2024  Volume 62, Issue 4, Page(s) 531–537

    Abstract: Backgroud: Oesophageal cancer patients are prone to early- and late-onset pneumonia after oesophagectomy. We aimed to investigate the incidence rate and impact on the long-term prognosis of late-onset pneumonia in oesophageal cancer survivors who ... ...

    Abstract Backgroud: Oesophageal cancer patients are prone to early- and late-onset pneumonia after oesophagectomy. We aimed to investigate the incidence rate and impact on the long-term prognosis of late-onset pneumonia in oesophageal cancer survivors who survived for at least one year after oesophagectomy without cancer recurrence.
    Methods: We retrospectively reviewed 233 patients with thoracic oesophageal cancer who underwent oesophagectomy with gastric conduit reconstruction between September 2009 and June 2019 at a tertiary referral hospital in Japan. Pneumonia that occurred ≥1 year after oesophagectomy was defined as late-onset pneumonia.
    Results: Among the 185 oesophageal cancer survivors, 31 (17%) developed late-onset pneumonia. The cumulative incidence rates of late-onset pneumonia 24, 36, and 60 months after oesophagectomy were 6.4%, 10%, and 21%, respectively, whereas pneumonia recurred at 21%, 31%, and 52% within 6, 12, and 24 months, respectively, after the first pneumonia. Chronic obstructive pulmonary disease, postoperative anastomotic leakage, and loss of skeletal muscle mass were independently associated with late-onset pneumonia, and a combination of these factors further increased the risk. Late-onset pneumonia with hospitalisation had the greatest negative impact on the long-term prognosis as non-cancer deaths (HR, 21; p < 0.001), followed by recurrent late-onset pneumonia (HR, 18; p < 0.001).
    Conclusions: Late-onset pneumonia in oesophageal cancer survivors is significantly associated with an increased risk of recurrent infections and non-cancer deaths. Chronic obstructive pulmonary disease and postoperative muscle loss are risk factors for late-onset pneumonia, and more intensive pharmacological and nutritional interventions should be considered to improve long-term prognosis after oesophagectomy.
    Language English
    Publishing date 2024-04-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2660821-2
    ISSN 2212-5353 ; 2212-5345
    ISSN (online) 2212-5353
    ISSN 2212-5345
    DOI 10.1016/j.resinv.2024.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Combined thoracoscopic and laparoscopic surgery for epiphrenic diverticulum with associated gastroesophageal reflux disease: a case report.

    Uchi, Yusuke / Ozawa, Soji / Ando, Tomofumi / Hayashi, Koki / Aoki, Takuma / Shimazu, Motohide

    Surgical case reports

    2024  Volume 10, Issue 1, Page(s) 17

    Abstract: Background: Surgery is indicated for symptomatic epiphrenic esophageal diverticula. Based on the features of a case, thoracoscopic or laparoscopic approaches may be used. Epiphrenic diverticula are often associated with esophageal motility disorders, ... ...

    Abstract Background: Surgery is indicated for symptomatic epiphrenic esophageal diverticula. Based on the features of a case, thoracoscopic or laparoscopic approaches may be used. Epiphrenic diverticula are often associated with esophageal motility disorders, but cases of reflux esophagitis have rarely been reported. In this report, we describe a case of an epiphrenic esophageal diverticulum with reflux esophagitis, which was successfully treated by thoracoscopic diverticulectomy and laparoscopic fundoplication.
    Case presentation: A 69-year-old man visited the hospital with a chief complaint of eructation and hiccup. Upper gastrointestinal endoscopy revealed a diverticulum in the left wall of the esophagus, which was 37-45 cm distal to the incisors. High-resolution manometry (HRM) showed no esophageal motility disorders. Due to the large size of the diverticulum, a thoracoscopic resection of the esophageal diverticulum was performed. Additionally, the patient had reflux esophagitis due to a hiatal hernia. The anti-reflux mechanism would be more impaired during the diverticulectomy; therefore, we decided that anti-reflux surgery should be performed simultaneously. Thoracoscopic esophageal diverticulectomy and laparoscopic Dor fundoplication were performed. The patient had an uncomplicated postoperative course and was discharged on the tenth operative day. He has been symptom-free without acid secretion inhibitors for 21 months after the surgery.
    Conclusions: We described a rare case of a large epiphrenic diverticulum with reflux esophagitis. A good surgical outcome was achieved by thoracoscopic resection of the diverticulum and laparoscopic Dor fundoplication.
    Language English
    Publishing date 2024-01-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2809613-7
    ISSN 2198-7793
    ISSN 2198-7793
    DOI 10.1186/s40792-024-01813-0
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  6. Article: Reactive lymphoid hyperplasia of the liver after surgery for advanced sigmoid colon cancer: a case report.

    Sunamura, Ken / Endo, Yutaka / Hayashi, Koki / Uchi, Yusuke / Ozawa, Soji / Shimazu, Motohide

    Journal of surgical case reports

    2024  Volume 2024, Issue 4, Page(s) rjae248

    Abstract: We report a case of reactive lymphoid hyperplasia (RLH) mimicking colorectal liver metastases (CRLM) on preoperative workup that was clinically indistinguishable. A 78-year-old woman was found to have locally-advanced sigmoid cancer (T4), and then ... ...

    Abstract We report a case of reactive lymphoid hyperplasia (RLH) mimicking colorectal liver metastases (CRLM) on preoperative workup that was clinically indistinguishable. A 78-year-old woman was found to have locally-advanced sigmoid cancer (T4), and then treated with radical sigmoidectomy. One year after the surgery, plain computed tomography (CT) revealed a low-density area in the right hepatic lobe. Metastatic liver tumors could not be ruled out with CT/ magnetic resonant imaging (MRI) and positron emission tomography-CT . Based on these findings, the patient was diagnosed with CRLM at S7 of the liver. The patient underwent right posterior sectionectomy. The tumor was adjacent to the right hepatic vein; however, no invasion was observed. The patient was pathologically diagnosed as having RLH. The patient showed no signs of recurrence 16 months after initial surgery. RLH is clinically indistinguishable from CRLM. Further evaluation is required to elucidate the effective strategies of detecting and treating hepatic RLH.
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjae248
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  7. Article ; Online: Essential updates 2020/2021: Recent topics in surgery and perioperative therapy for esophageal cancer.

    Ozawa, Soji / Uchi, Yusuke / Ando, Tomofumi / Hayashi, Koki / Aoki, Takuma

    Annals of gastroenterological surgery

    2023  Volume 7, Issue 3, Page(s) 346–357

    Abstract: In this review, we focused on four topics, namely, minimally invasive esophagectomy (MIE), robot-assisted minimally invasive esophagectomy (RAMIE), conversion and salvage surgery, and neoadjuvant and adjuvant therapy, based on notable reports published ... ...

    Abstract In this review, we focused on four topics, namely, minimally invasive esophagectomy (MIE), robot-assisted minimally invasive esophagectomy (RAMIE), conversion and salvage surgery, and neoadjuvant and adjuvant therapy, based on notable reports published in the years 2020 and 2021. It seems that while the short-term outcomes of minimally invasive Ivor Lewis esophagectomy (MIE-IL) were better than those of open Ivor Lewis esophagectomy (OE-IL), there were no significant differences in the long-term outcomes between MIE-IL and OE-IL. Similarly, the short-term outcomes of minimally invasive McKeown esophagectomy (MIE-MK) were better than those of open McKeown esophagectomy (OE-MK), while there were no significant differences in the long-term outcomes between MIE-MK and OE-MK. Furthermore, the short-term outcomes of robot-assisted minimally invasive Ivor Lewis esophagectomy (RAMIE-IL) were superior to those of completely minimally invasive Ivor Lewis esophagectomy (CMIE-IL). On the other hand, there were advantages and disadvantages in relation to the short-term outcomes of robot-assisted minimally invasive McKeown esophagectomy (RAMIE-MK) as compared with completely minimally invasive McKeown esophagectomy (CMIE-MK). However, there were no significant differences in the long-term outcomes between RAMIE-MK and CMIE-MK. Further research is needed to evaluate of short-term and long-term outcomes of transmediastinal esophagectomy with and without robotic assistance. Both induction chemotherapy and induction chemoradiotherapy appear to be promising to secure a higher rate of conversion surgery. Neoadjuvant chemoimmunotherapy and chemoimmunoradiotherapy have shown promising results and are expected as new powerful therapies.
    Language English
    Publishing date 2023-02-07
    Publishing country Japan
    Document type Journal Article ; Review
    ISSN 2475-0328
    ISSN (online) 2475-0328
    DOI 10.1002/ags3.12657
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Clinical significance of sarcopenic dysphagia for patients with esophageal cancer undergoing esophagectomy: A review.

    Oguma, Junya / Ozawa, Soji / Ishiyama, Koshiro / Daiko, Hiroyuki

    Annals of gastroenterological surgery

    2022  Volume 6, Issue 6, Page(s) 738–745

    Abstract: The relationships among esophagectomy for esophageal cancer, dysphagia, and sarcopenia are still unclear. We considered appropriate interventions for patients with resectable esophageal cancer for the purpose of reducing postoperative dysphagia and ... ...

    Abstract The relationships among esophagectomy for esophageal cancer, dysphagia, and sarcopenia are still unclear. We considered appropriate interventions for patients with resectable esophageal cancer for the purpose of reducing postoperative dysphagia and aspiration pneumonia. Dysphagia in patients with esophageal cancer is caused by patient characteristics, such as pathophysiology and age, or complications after esophagectomy. Recently, sarcopenic dysphagia, defined as dysphagia associated with whole-body sarcopenia, has attracted attention in various fields, and a large proportion of patients with esophageal cancer are expected to have sarcopenic dysphagia. Our systematic review and meta-analysis suggested that preoperative sarcopenia in patients with esophageal cancer is related to pulmonary complications after esophagectomy, and some reports also suggested that sarcopenia in swallowing-related muscles, such as the geniohyoid muscle and tongue, might be associated with postoperative pneumonia or dysphagia after esophagectomy. However, clinical studies on sarcopenic dysphagia in patients with esophageal cancer have been limited. To prevent sarcopenic dysphagia after esophagectomy, perioperative interventions involving not only swallowing rehabilitation, but also physical exercise and nutritional support are important. Moreover, several reports have suggested that the chin-down maneuver might be effective for preventing aspiration after an esophagectomy. To inhibit the progression of sarcopenic dysphagia after esophagectomy, evaluations and interventions by multidisciplinary staff are likely to be necessary.
    Language English
    Publishing date 2022-07-28
    Publishing country Japan
    Document type Journal Article ; Review
    ISSN 2475-0328
    ISSN (online) 2475-0328
    DOI 10.1002/ags3.12603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Innovation in extending a surgical field in the superior mediastinum during surgery of esophageal cancer under thoracoscopy while the patient in a prone position].

    Ozawa, Soji

    Kyobu geka. The Japanese journal of thoracic surgery

    2014  Volume 67, Issue 3, Page(s) 202

    MeSH term(s) Aged ; Esophagectomy/methods ; Humans ; Male ; Mediastinum ; Prone Position ; Thoracoscopy
    Language Japanese
    Publishing date 2014-03
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 603899-2
    ISSN 0021-5252
    ISSN 0021-5252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 11: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Pharmacological treatment to reduce pulmonary morbidity after esophagectomy.

    Shinozaki, Hiroharu / Matsuoka, Tadashi / Ozawa, Soji

    Annals of gastroenterological surgery

    2021  Volume 5, Issue 5, Page(s) 614–622

    Abstract: Esophagectomy for esophageal cancer is one of the most invasive procedures in gastrointestinal surgery. An invasive surgical procedure causes postoperative lung injury through the surgical procedure and one-lung ventilation during anesthesia. Lung injury ...

    Abstract Esophagectomy for esophageal cancer is one of the most invasive procedures in gastrointestinal surgery. An invasive surgical procedure causes postoperative lung injury through the surgical procedure and one-lung ventilation during anesthesia. Lung injury developed by inflammatory response to surgical insults and oxidative stress is associated with pulmonary morbidity after esophagectomy. Postoperative pulmonary complications negatively affect the long-term outcomes; therefore, an effort to reduce lung injury improves overall survival after esophagectomy. Although significant evidence has not been established, various pharmacological treatments for reducing lung injury, such as administration of a corticosteroid, neutrophil elastase inhibitor, and vitamins are considered to have efficacy for pulmonary morbidity. In this review we survey the following topics: mediators during the perioperative periods of esophagectomy and the efficacy of pharmacological therapies for patients with esophagectomy on pulmonary complications.
    Language English
    Publishing date 2021-07-01
    Publishing country Japan
    Document type Journal Article ; Review
    ISSN 2475-0328
    ISSN (online) 2475-0328
    DOI 10.1002/ags3.12469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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