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  1. Book: Special issue on: "Modern plant breeding approaches"

    Özkan, Hakan

    (Turkish journal of agriculture and forestry ; 39,4)

    2015  

    Title variant Modern plant breeding approaches
    Author's details [guest ed. Hakan Özkan ...]
    Series title Turkish journal of agriculture and forestry ; 39,4
    Collection
    Language English
    Size S. 515 - 600 : Ill., graph. Darst.
    Publisher TÜBITAK
    Publishing place Ankara
    Publishing country Turkey
    Document type Book
    HBZ-ID HT018787666
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  2. Article ; Online: Utilizing the Potential of Waste Hemp Reinforcement: Investigating Mechanical and Thermal Properties of Polypropylene and Polylactic Acid Biocomposites.

    Yılmaz, Anıl / Özkan, Hakan / Genceli Güner, F Elif

    ACS omega

    2024  Volume 9, Issue 8, Page(s) 8818–8828

    Abstract: Hemp has gained significant popularity for its diverse applications; however, this study explores the untapped potential of waste hemp (wH) as a cost-effective and sustainable bioadditive for the development of high-performance biocomposites. wH offers ... ...

    Abstract Hemp has gained significant popularity for its diverse applications; however, this study explores the untapped potential of waste hemp (wH) as a cost-effective and sustainable bioadditive for the development of high-performance biocomposites. wH offers advantages such as low cost, easy availability, and suitability for extrusion. Polypropylene (PP) and poly(lactic acid) (PLA) served as polymer matrices for this investigation. In order to enhance the interaction between the wH and polymer matrices, alkaline and silane pretreatments were applied to the wHs of both matrices. At the same time, the MA-
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c06240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Grain quality traits within the wheat (Triticum spp.) genepool: prospects for improved nutrition through de novo domestication.

    Zeibig, Frederike / Kilian, Benjamin / Özkan, Hakan / Pantha, Sumitra / Frei, Michael

    Journal of the science of food and agriculture

    2024  Volume 104, Issue 7, Page(s) 4400–4410

    Abstract: Background: Wild relatives of wheat (Triticum spp.) harbor beneficial alleles for potential improvement and de novo domestication of selected genotypes with advantageous traits. We analyzed the nutrient composition in wild diploid and tetraploid wheats ... ...

    Abstract Background: Wild relatives of wheat (Triticum spp.) harbor beneficial alleles for potential improvement and de novo domestication of selected genotypes with advantageous traits. We analyzed the nutrient composition in wild diploid and tetraploid wheats and their domesticated diploid, tetraploid and hexaploid relatives under field conditions in Germany and compared them with modern Triticum aestivum and Triticum durum cultivars. Grain iron (Fe) and zinc (Zn) concentrations, phytate:mineral molar ratios, grain protein content (GPC) and antioxidant activity were analyzed across 125 genotypes.
    Results: Grain Fe and Zn concentrations in wild wheats were 72 mg kg
    Conclusion: Our results indicate alteration of grain quality during domestication. T. araraticum has promising genotypes with advantageous grain quality characteristics that could be selected for de novo domestication. Favorable nutritional traits in the GGAA wheat lineage (T. araraticum and T. zhukovskyi) hold promise for improving grain quality traits. © 2024 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
    MeSH term(s) Triticum/chemistry ; Tetraploidy ; Antioxidants/metabolism ; Phytic Acid/metabolism ; Domestication ; Edible Grain/chemistry ; Zinc/metabolism
    Chemical Substances Antioxidants ; Phytic Acid (7IGF0S7R8I) ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 184116-6
    ISSN 1097-0010 ; 0022-5142
    ISSN (online) 1097-0010
    ISSN 0022-5142
    DOI 10.1002/jsfa.13328
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A new genetic linkage map in einkorn wheat (Triticum monococcum) detects two major QTLs for heading date in chromosome 2A and 5A, probably corresponding to the photoperiod and vernalization genes

    Sesiz, Uğur / Özkan, Hakan

    Plant breeding. 2022 Feb., v. 141, no. 1

    2022  

    Abstract: Einkorn harbours a wide range of genetic diversity for agronomically important traits. Heading date is one of the important traits for the adaptation of wheat species to various climatic conditions and the cultivation in diverse regions and seasons. In ... ...

    Abstract Einkorn harbours a wide range of genetic diversity for agronomically important traits. Heading date is one of the important traits for the adaptation of wheat species to various climatic conditions and the cultivation in diverse regions and seasons. In this study, DArTseq and SSR marker‐based linkage map of einkorn wheat was constructed using 150 recombinant inbred lines (RILs) derived from a cross between ID1623 and MONLIS. The linkage map involved 865 SNP, 787 Silico‐DArT and 16 SSR DNA markers mapped to 741 loci in seven linkage groups and covered 1158.54 cM with an average density of 1.56 cM/locus. Four QTLs associated with heading date, detected in all environments by composite interval mapping (CIM), were positioned across the 2A, 5A and 7A einkorn wheat chromosomes. Two major and stable QTLs, QThd‐2A.2 and QThd 5A.1, were identified on chromosomes 2A and 5A, respectively. These QTLs probably coincide with photoperiod and vernalization genes in accordance with previously published maps. The new map will facilitate quantitative trait locus mapping, map‐based cloning and comparative genomics in wheat species.
    Keywords DNA ; Triticum monococcum subsp. monococcum ; chromosome mapping ; genetic variation ; genomics ; loci ; quantitative trait loci ; vernalization ; wheat
    Language English
    Dates of publication 2022-02
    Size p. 12-25.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 232853-7
    ISSN 0179-9541
    ISSN 0179-9541
    DOI 10.1111/pbr.12985
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Experimental and Statistical Study on the Properties of Basic Oxygen Furnace Slag and Ground Granulated Blast Furnace Slag Based Alkali-Activated Mortar.

    Özkan, Hakan / Miyan, Nausad / Kabay, Nihat / Omur, Tarik

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 6

    Abstract: Basic oxygen furnace slag (BOFS) is a waste material generated during the steelmaking process and has the potential to harm both the environment and living organisms when disposed of in a landfill. However, the cementitious properties of BOFS might help ... ...

    Abstract Basic oxygen furnace slag (BOFS) is a waste material generated during the steelmaking process and has the potential to harm both the environment and living organisms when disposed of in a landfill. However, the cementitious properties of BOFS might help in utilizing this waste as an alternative material in alkali-activated systems. Therefore, in this study, BOFS and blast furnace slag were activated with varying dosages of NaOH, and the fresh, physical, mechanical, and microstructural properties were determined along with statistical analysis to reach the optimal mix design. The test results showed that an increase in BOFS content decreased compressive and flexural strengths, whereas it slightly increased the water absorption and permeable pores of the tested mortar samples. On the contrary, the increase in NaOH molarity resulted in a denser microstructure, reduced water absorption and permeable pores, and improved mechanical properties. Statistically significant relationships were obtained through response surface methodology with optimal mix proportions, namely, (i) 24.61% BOFS and 7.74 M and (ii) 20.00% BOFS and 8.90 M, which maximize the BOFS content with lower molarity and improve the mechanical properties with lower water absorption and porosity, respectively. The proposed methodology maximizes the utilization of waste BOFS in alkali-activated systems and may promote environmental and economic benefits.
    Language English
    Publishing date 2023-03-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16062357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Genome‐wide association analysis of coleoptile length and interaction with plant height in durum wheat

    Sesiz, Uğur / Alsaleh, Ahmad / Bektas, Harun / Topu, Mustafa / Özkan, Hakan

    Agronomy Journal. 2024 , v. 116, no. 1 p.1-17

    2024  

    Abstract: Genotypes with longer coleoptiles can be sown in deep soil layers to reach the underground moisture needed for germination in dry areas. Developing new varieties with longer coleoptiles and shorter plant heights would be novel for wheat breeding and ... ...

    Abstract Genotypes with longer coleoptiles can be sown in deep soil layers to reach the underground moisture needed for germination in dry areas. Developing new varieties with longer coleoptiles and shorter plant heights would be novel for wheat breeding and production. In this study, coleoptile lengths of a panel of durum wheat (Triticum turgidum ssp. durum) genotypes were determined, and 14,255 DArTseq (SNP and Silico‐DArT) markers were used to identify coleoptile length‐associated markers by genome‐wide association study (GWAS). A wide genetic variation was accounted for both coleoptile length and plant height. The genetic relationships between coleoptile length and plant height were evaluated using plant height values from five different environments. Two environmentally stable MTAs were identified, one for coleoptile length (QCol.su.4BS) and one for plant height (QPh.su.4BS). These MTAs were located on the short arm of chromosome 4B, with LOD scores up to 12.00 and 17.00, respectively. A relatively high LD (r² = 0.71) was accounted for between QCol.su.4BS and QPh.su.4BS. The LD block intervals of the MTAs overlapped with some genes with roles in plant growth and development. The functions of plausible candidate genes tell us that QCol.su.4BS may be controlling coleoptile length, whereas QPh.su.4BS may be regulating plant height. The combination of the two loci would be desirable. In conclusion, this study sheds light on the genetic control of coleoptile length and its relationship with plant height in durum wheat.
    Keywords Triticum turgidum subsp. durum ; agronomy ; chromosomes ; coleoptiles ; durum wheat ; genetic variation ; genome-wide association study ; germination ; plant growth ; plant height ; soil
    Language English
    Dates of publication 2024-01
    Size p. 1-17.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 410332-4
    ISSN 1435-0645 ; 0002-1962
    ISSN (online) 1435-0645
    ISSN 0002-1962
    DOI 10.1002/agj2.21488
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Next-Generation-Sequencing-Based Simple Sequence Repeat (SSR) Marker Development and Linkage Mapping in Lentil (

    Topu, Mustafa / Sesiz, Uğur / Bektaş, Harun / Toklu, Faruk / Özkan, Hakan

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 7

    Abstract: Simple sequence repeats (SSRs) are highly versatile markers in genetic diversity analysis and plant breeding, making them widely applicable. They hold potential in lentil ( ...

    Abstract Simple sequence repeats (SSRs) are highly versatile markers in genetic diversity analysis and plant breeding, making them widely applicable. They hold potential in lentil (
    Language English
    Publishing date 2023-07-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13071579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Adulthood asthma as a consequence of childhood adversity: a systematic review of epigenetically affected genes.

    Saygideger, Yasemin / Özkan, Hakan / Baydar, Oya / Yilmaz, Ozge

    Journal of developmental origins of health and disease

    2022  Volume 13, Issue 6, Page(s) 674–682

    Abstract: There is an accumulating data that shows relation between childhood adversity and vulnerability to chronic diseases as well as epigenetic influences that in turn give rise to these diseases. Asthma is one of the chronic diseases that is influenced from ... ...

    Abstract There is an accumulating data that shows relation between childhood adversity and vulnerability to chronic diseases as well as epigenetic influences that in turn give rise to these diseases. Asthma is one of the chronic diseases that is influenced from genetic regulation of the inflammatory biomolecules and therefore the hypothesis in this research was childhood adversity might have caused epigenetic differentiation in the asthma-related genes in the population who had childhood trauma. To test this hypothesis, the literature was systematically reviewed to extract epigenetically modified gene data of the adults who had childhood adversity, and affected genes were further evaluated for their association with asthma. PRISMA guidelines were adopted and PubMed and Google Scholar were included in the searched databases, to evaluate epigenetic modifications in asthma-related genes of physically, emotionally or sexually abused children. After retrieving a total of 5245 articles, 36 of them were included in the study. Several genes and pathways that may contribute to pathogenesis of asthma development, increased inflammation, or response to asthma treatment were found epigenetically affected by childhood traumas. Childhood adversity, causing epigenetic changes in DNA, may lead to asthma development or influence the course of the disease and therefore should be taken into account for the prolonged health consequences.
    MeSH term(s) Child ; Adult ; Humans ; Adverse Childhood Experiences ; Asthma/genetics ; Epigenesis, Genetic ; Inflammation
    Language English
    Publishing date 2022-03-08
    Publishing country England
    Document type Systematic Review ; Journal Article
    ZDB-ID 2554780-X
    ISSN 2040-1752 ; 2040-1744
    ISSN (online) 2040-1752
    ISSN 2040-1744
    DOI 10.1017/S2040174422000083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Application of unilateral rhomboid intercostal and subserratus plane block for analgesia after laparoscopic cholecystectomy: a quasi-experimental study.

    Ökmen, Korgün / Gürbüz, Hande / Özkan, Hakan

    Korean journal of anesthesiology

    2021  Volume 75, Issue 1, Page(s) 79–85

    Abstract: Background: Interfascial plane block can be used to treat postoperative pain after laparoscopic surgery. This study aimed to investigate the effect of ultrasound-guided unilateral rhomboid intercostal and subserratus plane (RISS) block after ... ...

    Abstract Background: Interfascial plane block can be used to treat postoperative pain after laparoscopic surgery. This study aimed to investigate the effect of ultrasound-guided unilateral rhomboid intercostal and subserratus plane (RISS) block after laparoscopic cholecystectomy on the amount of analgesic consumption.
    Methods: Fifty patients who underwent laparoscopic cholecystectomy were included in this quasi-experimental study. Patients fulfilling the inclusion criteria were analyzed in two groups: RISS group (RISS block with 20 ml of 0.25% bupivacaine + intravenous patient-controlled analgesia [IV-PCA] tramadol [n = 25]); and Control group (IV-PCA tramadol [n = 25]). The primary outcome was the total amount of tramadol used over 24 h. Secondary outcomes included side effects, additional analgesic use, and postoperative pain (at rest and during activity) at 2, 6, 12, and 24 h according to numerical rating scale (NRS) scores.
    Results: Postoperative tramadol consumption at 24 h was significantly lower in the RISS group than in the Control group (P < 0.001). Resting NRS scores at 2 h and 6 h were significantly lower in the RISS group. NRS scores during movement in the RISS group were significantly lower at 2, 6, and 12 h postoperatively. There was no statistically significant difference in the rate of side effects and additional analgesic use between the groups (P > 0.05).
    Conclusions: Unilateral RISS block was an effective method for pain management after laparoscopic cholecystectomy and can be used as a part of multimodal analgesia.
    MeSH term(s) Analgesia, Patient-Controlled ; Cholecystectomy, Laparoscopic/adverse effects ; Humans ; Nerve Block/methods ; Pain Management ; Prospective Studies ; Ultrasonography, Interventional
    Language English
    Publishing date 2021-07-20
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2557340-8
    ISSN 2005-7563 ; 2005-7563
    ISSN (online) 2005-7563
    ISSN 2005-7563
    DOI 10.4097/kja.21229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Erectile dysfunction after surgery for rectal cancer: a prospective study.

    Gökçe, Aylin Hande / Özkan, Hakan

    Turkish journal of surgery

    2019  Volume 35, Issue 4, Page(s) 293–298

    Abstract: Objectives: Erectile dysfunction may occur as a complication of surgical treatment of rectal cancer in male patients. We compared the rates of postoperative erectile dysfunction and response to medical treatment after low anterior resection (LAR) and ... ...

    Abstract Objectives: Erectile dysfunction may occur as a complication of surgical treatment of rectal cancer in male patients. We compared the rates of postoperative erectile dysfunction and response to medical treatment after low anterior resection (LAR) and Miles' procedures.
    Material and methods: Fifty patients who underwent the Miles' procedure or LAR were prospectively assessed. This study includes fifty patients with stages 1 and stage 2 rectal cancer based on clinical and radiologic assessments, who underwent Miles' (25 out of 50 patients underwent the Miles'procedure and ) or LAR (25 patients underwent LAR) procedures were prospectively assessed. The International Index of Erectile Function (IIEF) form was, used in the assessment to assess erectile dysfunction. This questionnaire, was administered preoperatively and 6 months postoperatively. For the patients with IIEF scores ≤ 25 at postoperative 6th months, tadalafil 5 mg is was given for 12 weeks and IIEF is was repeated after then.
    Results: No significant differences were found in mean IIEF scores preoperatively (p= 0.695). In both groups, IIEF scores were significantly lower postoperatively compared with preoperatively (p= 0.00001, LAR; p= 0.00001, Miles'). Mean postoperative IIEF scores were significantly lower in patients who underwent Miles' compared with the LAR procedures (p= 0.0001). For patients with IIEF scores ≤ 25 at 6 months, tadalafil 5 mg was given for 12 weeks and IIEF scores were better in both groups (p= 0.00001).
    Conclusion: The erectile dysfunction rate after Miles' procedure was significantly higher than the rate of patients who developed erectile dysfunction after LAR surgery. We tried to emphasize that in after LAR surgery. We should not be concerned only with cancer treatment surgically in rectal tumour patients, but remember that situations affecting their social life, such as postoperative erectile dysfunction, have medical and psychologic importance.
    Language English
    Publishing date 2019-12-16
    Publishing country Turkey
    Document type Journal Article
    ISSN 2564-6850
    ISSN 2564-6850
    DOI 10.5578/turkjsurg.4397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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