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  1. Article ; Online: Promoting adolescent health: health literacy, self-efficacy and internet use.

    Ceylan, Dilara / Akan-Çelen, Feyza Nur / Özkan, Seçil / Aycan, Zehra

    The Turkish journal of pediatrics

    2022  Volume 64, Issue 1, Page(s) 110–121

    Abstract: Background: Adolescents are mostly considered as a healthy population; however, failure to acquire positive health behaviors during this period makes them vulnerable to poor health outcomes and long-term chronic disorders. Health literacy is one of the ... ...

    Abstract Background: Adolescents are mostly considered as a healthy population; however, failure to acquire positive health behaviors during this period makes them vulnerable to poor health outcomes and long-term chronic disorders. Health literacy is one of the most influential parameters in promoting adolescent health. This study aimed to determine the level and promoters of health literacy in adolescents, emphasize the importance of internet use, and evaluate the relationship between self-efficacy and health literacy.
    Methods: A total of 756 adolescents aged 15 and 18 years attending two high schools in socioeconomically different districts in Ankara, Turkey were included in this cross-sectional study. A survey consisting of descriptive questions, a health literacy survey, and a general self-efficacy scale were used to collect data. p < 0.05 was considered statistically significant.
    Results: Among the adolescents who participated in the study, the level of health literacy was inadequatelimited in 56.1%, sufficient in 30.1%, and excellent in 13.8%. A statistically significant correlation was found between health literacy and general self-efficacy levels (r: .412, p < 0.001). There was also a statistically significant difference between the health literacy groups in terms of the education level of the adolescents` mothers, internet use frequency, and self-efficacy level. The multivariate logistic regression analysis revealed that the participants whose mothers had only received primary school education or no formal education, those that were not using the internet regularly, those that did not search health information on the internet, and those with poor self-efficacy levels were more likely to have an inadequate level of health literacy [odds ratio (OR)=2.6, 95% confidence interval (CI)=1.4-4.9; OR=5.5, 95% CI=1.2-25.1; OR=1.7, 95% CI=1.1-2.9; and OR=3.7, 95% CI=2.6- 5.2, respectively].
    Conclusions: In this study, it was concluded that the adolescents` health literacy and general self-efficacy levels were related. Furthermore, the health literacy level of the adolescents was associated with internet use and maternal education status.
    MeSH term(s) Adolescent ; Adolescent Health ; Cross-Sectional Studies ; Health Literacy ; Humans ; Internet ; Internet Use ; Self Efficacy ; Surveys and Questionnaires
    Language English
    Publishing date 2022-03-21
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 123487-0
    ISSN 2791-6421 ; 0041-4301
    ISSN (online) 2791-6421
    ISSN 0041-4301
    DOI 10.24953/turkjped.2021.1264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Socioeconomic Factors Related to Prevalence, Severity, and Contact Coverage of Depression in Primary Health Care.

    Tüzün, Hakan / Demirköse, Hacer / Özkan, Seçil / İlhan, Mustafa Necmi

    Psychiatry and clinical psychopharmacology

    2021  Volume 31, Issue 4, Page(s) 457–467

    Abstract: Background: We determine factors related to the prevalence, severity, and contact coverage of depression using the Patient Health Questionnaire-9.: Methods: This cross-sectional study included 1059 individuals who applied to primary health care in ... ...

    Abstract Background: We determine factors related to the prevalence, severity, and contact coverage of depression using the Patient Health Questionnaire-9.
    Methods: This cross-sectional study included 1059 individuals who applied to primary health care in Ankara before the onset of pandemic restrictions. Contact coverage was evaluated to include mental health care users.
    Results: The prevalence of depression was 22.9%. Individuals who were unemployed (OR: 3.832; 95% CI: 2.053-7.151), women (OR: 1.646; 95% CI: 1.158-2.340), those without social support (OR: 1.933; 95% CI: 1.219-3.065), those who did not receive formal education (OR: 2.631; 95 % CI: 1.312-5.275), lower-income group (OR: 1.528; 95% CI: 1.071-2.180), and unmarried or divorced (OR: 2.644; 95% CI: 1.324-5.281) were found to be at risk of developing depression. Based on the linear regression model including patients diagnosed with depression, individuals who were unemployed (standardized β: 0.190), women (standardized β: 0.075), those without social support (standardized β: 0.096), and those who were unmarried or single (standardized β: 0.147) had the highest scale scores. Contact coverage for depression was 31.0%. Contact coverage was more likely in the upper-income group (OR: 2.239, 95% CI: 1.173-4.273).
    Conclusion: Although depression is common among primary health care applicants, contact coverage is low. Developing screening programs for depression in primary health care may help improve community mental health. Socioeconomic factors that contribute to the emergence, severity, and contact coverage of depression indicate health inequalities. The development and severity of depression are mostly due to unemployment, which suggests the importance of employment-enhancing policies.
    Language English
    Publishing date 2021-12-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2964147-0
    ISSN 2475-0581 ; 2475-0573
    ISSN (online) 2475-0581
    ISSN 2475-0573
    DOI 10.5152/pcp.2021.21051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: How health literacy associates with healthcare utilization and health promotion behaviours in Turkey?: Contributions to discussions concerning the Anderson model and ecological models.

    Tüzün, Hakan / Özkan, Seçil / Dikmen, Asiye Uğraş / Aksakal, Nur Baran / Çalışkan, Deniz / Taşçı, Özge / Ünal, Selime Ceylan

    The International journal of health planning and management

    2023  Volume 38, Issue 4, Page(s) 986–998

    Abstract: Background: This study examined how health literacy (HL) levels are associated with health care utilization (HCU) and health promotion behaviours (HPB) in Turkey.: Methods: We conducted face-to-face interviews and utilised the Turkish HL Scale-32 (n = ...

    Abstract Background: This study examined how health literacy (HL) levels are associated with health care utilization (HCU) and health promotion behaviours (HPB) in Turkey.
    Methods: We conducted face-to-face interviews and utilised the Turkish HL Scale-32 (n = 6228).
    Results: HL score was inversely related to the number of outpatient admissions (OAs) (β = -0.001) and emergency department admissions (EAs) (β = -0.006) in the Poisson regression model. Sex, age, perceived health, income group, and education level were other variables related to the number of OAs and EAs. Health literacy levels were related to physical activity (PA) (for excellent HL, OR: 3.93 (95% CI: 2.54-6.08)) and acquiring healthy eating habits (HEHs) (for excellent HL, OR: 3.56 (95% CI: 2.40-5.29) in the logistic regression model. Education levels are related to PA, HEHs, and smoking cessation or reduction. Income groups, except those with very sufficient income, are related to PA and HEHs.
    Conclusion: Improving HL can help reduce health admissions. The relationship of HCU with gender, age, education, perceived health, and income group supports the Anderson model. Limited HL groups should be prioritised as risk groups in health promotion programs. The association of HL and socio-economic variables with HPB supports the ecological model.
    MeSH term(s) Health Literacy ; Turkey ; Cross-Sectional Studies ; Patient Acceptance of Health Care ; Health Promotion ; Surveys and Questionnaires
    Language English
    Publishing date 2023-04-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 632786-2
    ISSN 1099-1751 ; 0749-6753
    ISSN (online) 1099-1751
    ISSN 0749-6753
    DOI 10.1002/hpm.3640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Assessment of anxiety in elderly population during the COVID-19 pandemic and the impact of compulsory home-stay in the central districts of Ankara, Turkey: A quantitative, qualitative mixed method study.

    Sirin, Hulya / Ahmadi, Ahmad Abed / Ketrez, Gamze / Ozbeyaz, Cagri / Dikmen, Asiye Ugras / Ozkan, Secil

    International journal of geriatric psychiatry

    2021  Volume 36, Issue 11, Page(s) 1785–1794

    Abstract: Objective: This study aimed to determine the level of anxiety in elderly individuals during the COVID-19 pandemic in Ankara province of Turkey and determine its associated factors.: Methods: A quantitative, qualitative mixed-method study performed in ...

    Abstract Objective: This study aimed to determine the level of anxiety in elderly individuals during the COVID-19 pandemic in Ankara province of Turkey and determine its associated factors.
    Methods: A quantitative, qualitative mixed-method study performed in 1-10 June 2020 during the compulsory home-stay for elderly people in Turkey. The quantitative study was conducted using a structured online questionnaire with 278 participants aged 65 or older. The Geriatric Anxiety Inventory (GAI) was used to assess the anxiety. An in-depth interview with 20 participants was used to fill the gap of face-to-face interview due to pandemic situation and strengthen the results of quantitative survey. Qualitative and quantitative data were analyzed separately.
    Results: Of all participants, 88 (31.7%) had a score above the cut-off point for GAI. The prevalence of Generalized Anxiety Disorder (GAD) was significantly higher in female (37.8%) than in male (23.8%). Female gender, economic loss, uncertainty, and the time participants expend to follow news about COVID-19 pandemic were risk factors of GAD. On the other hand, higher education level, hobbies, and regular physical activity were protective factors against GAD.
    Conclusion: During the pandemic, social isolation and lockdown for elderly people make serious risk factor for their mental well-being. Measures must be taken to support the psychological well-being of elderly by promoting physical activity and hobbies at home, and reducing their economic concerns.
    MeSH term(s) Aged ; Anxiety/epidemiology ; Anxiety Disorders/epidemiology ; COVID-19 ; Communicable Disease Control ; Female ; Humans ; Male ; Pandemics ; SARS-CoV-2 ; Turkey/epidemiology
    Language English
    Publishing date 2021-07-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 806736-3
    ISSN 1099-1166 ; 0885-6230
    ISSN (online) 1099-1166
    ISSN 0885-6230
    DOI 10.1002/gps.5600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The prevalence and distribution of human papillomavirus in 4267 Turkish women with or without cervical lesions: A hospital-based study.

    Altay-Kocak, Aylin / Kazanci, Ferah / Dogu-Tok, Canan / Onan, Anil / Erdem, Ozlem / Ozkan, Secil / Bozdayi, Gulendam

    Journal of medical virology

    2022  Volume 94, Issue 10, Page(s) 5026–5032

    Abstract: In the present study, it was aimed to screen the genotypes of human papillomavirus (HPV) retrospectively in women with gynecological symptoms who were admitted to a tertiary care university hospital in Ankara, Turkey. A total of 4267 cervical swab ... ...

    Abstract In the present study, it was aimed to screen the genotypes of human papillomavirus (HPV) retrospectively in women with gynecological symptoms who were admitted to a tertiary care university hospital in Ankara, Turkey. A total of 4267 cervical swab samples of women aged 18-79 years were sent to Medical Virology Laboratory from January 2017 to November 2020. Nucleic acid extraction and amplification of samples were done by an automated system. The test can detect 14 high-risk HPV (HR-HPV) types in a single analysis that performs a real-time polymerase chain reaction, by providing individual results on the highest-risk genotypes HPV 16 and HPV 18 and pooled results on other high-risk genotypes (OHR-HPV) (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68). HPV DNA positivity was detected in 14.2% (605/4267) of the samples. HPV type 16 and type 18 were detected in 2.4% and 0.7% of the samples, respectively. OHR-HPV types were found in 8.8% of the samples. Of the 1.9% and 0.4% samples had mixed types with type 16+ OHR-HPV and type 18+ OHR-HPV, respectively. The results of this study presented the rates of HR-HPV genotypes of a university hospital in Ankara, over a 4-year period. It was observed that the positivity rate of type 18 is decreasing and some OHR-HPV types are increasing. HPV vaccination is not in the national immunization program in Turkey yet, however, HPV vaccines are available and the vaccination rates for women are increasing.
    MeSH term(s) Alphapapillomavirus/genetics ; DNA, Viral/analysis ; DNA, Viral/genetics ; Female ; Genotype ; Hospitals ; Human papillomavirus 16/genetics ; Human papillomavirus 18/genetics ; Humans ; Papillomaviridae/genetics ; Papillomavirus Infections ; Papillomavirus Vaccines ; Prevalence ; Retrospective Studies ; Turkey/epidemiology ; Uterine Cervical Neoplasms
    Chemical Substances DNA, Viral ; Papillomavirus Vaccines
    Language English
    Publishing date 2022-06-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.27921
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: COVID-19 epidemiology and intervention strategies in Turkey/ Türkiye COVID-19 Epidemiyolojisi ve Müdahale Stratejileri

    Dikmen, Asiye Ugras / Kina, Hatice Mediha / Özkan, Seçil / Ilhan, Mustafa Necmi

    Gazi Med. J.

    Abstract: Turkey is one of the countries which have taken precautions against the COVID-19. The precautions taken brought the first case in our country to be seen later than many countries and to spread the epidemic less. After the first COVID-19 case was detected ...

    Abstract Turkey is one of the countries which have taken precautions against the COVID-19. The precautions taken brought the first case in our country to be seen later than many countries and to spread the epidemic less. After the first COVID-19 case was detected in our country on March 11, 2020, the four periods of 14 days have been examined separately about the course of the epidemic and the public health interventions implemented in these periods. And the results it has generated between the periods have been evaluated. The steady decline in case of increase shows we have controlled the epidemic.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #681805
    Database COVID19

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  7. Article ; Online: COVID-19 Epidemiyolojisi

    UĞRAŞ DİKMEN, Asiye / KINA, Mediha / ÖZKAN, Seçil / İLHAN, Mustafa Necmi

    29-36 ; 2587-1641 ; Journal of Biotechnology and Strategic Health Research

    Pandemiden Ne Öğrendik ; Epidemiology of COVID-19: What We Learn From Pandemic

    2020  

    Abstract: 2019’un sonunda Çin’in Hubei eyaleti Wuhan şehrinde ortaya çıkan ve yayılanSARS-CoV-2 virüsü sonucu meydana gelen COVID-19 pandemisihalen ciddi bir halk sağlığı problemi olarak etkisini sürdürmektedir. Virüsün yarasa kaynaklı olduğu düşünülmektedir. ... ...

    Abstract 2019’un sonunda Çin’in Hubei eyaleti Wuhan şehrinde ortaya çıkan ve yayılanSARS-CoV-2 virüsü sonucu meydana gelen COVID-19 pandemisihalen ciddi bir halk sağlığı problemi olarak etkisini sürdürmektedir. Virüsün yarasa kaynaklı olduğu düşünülmektedir. Hastalık damlacık ve temas yolu ile insandan insana bulaşmaktadır. İnkübasyon süresi ortalaması 4-5 gün (0-14 gün) olarak gösterilmiştir. En yaygın semptomları ateş, kuru öksürük ve nefes darlığıdır. Hastalık ileri yaş ve komorbid hastalığı olan kişilerde şiddetli ve mortal seyredebilmektedir. Erkeklerde daha fazla fatalite hızı gösterilmiştir. Fatalite hızı dünya genelinde %2-3 olarak değişmektedir. Yaş arttıkça fatalite hızı artmaktadır. Rutin BCG aşısı politikasının mortaliteyi azalttığı düşünülmektedir.Teşhis olası vakalarda virüsün solunum sekresyonlarında özel moleküler testlerle gösterilmesi ile konur. Klinik şüphe varlığında tedavi planlamasında akciğer grafisi ve bilgisayarlı tomografi gibi görüntüleme yöntemleri kullanılmaktadır. Esas olarak destekleyii ve ampirik tedavi uygulanmakta olup spesifik tedavisi ve aşısı henüz yoktur. İnsanların temasının azaltılması, kesin ve şüpheli vakaların izolasyonu ve bulaştan korunmak için kişisel koruyucu ekipmanların etkin kullanımı salgın ile mücadelede çok büyük öneme sahiptir.

    The COVID-19 outbreak, which occurred as a result of the SARS-CoV-2 virus that spread in the city of Wuhan, Hubei province in late 2019, is a public health crisis. The virus is thought to be caused by bat. The disease is transmitted from person to person through droplets and contact. Incubation time is shown as 4-5 days (0-14 days). The most common symptoms are fever, dry cough, and shortness of breath. The disease can be severe and fatal in people with old age and comorbid disease. More fatality rates were shown in men than in women. The global fatality rate is known as 2-3%. As the age increases, the rate of fatality increases. Routine BCG vaccine policy is thought to reduce mortality. The diagnosis is made in possible cases by showing the virus in respiratory secretions by special molecular tests. In the presence of clinical suspicion, imaging methods such as chest radiography and computed tomography are used in treatment planning. Mainly supportive and empirical treatment is used and specific treatment and vaccine are not yet available. Effective use of personal protective equipment to reduce contact with people, isolation of precise and suspicious cases and protection from contamination is crucial to combating the epidemic.
    Keywords SARS-CoV-2,Salgın,COVID-19,Pandemi ; SARS-CoV-2,Epidemic,COVID-19,Pandemic ; covid19
    Language Turkish
    Publishing date 2020-04-30T00:00:00Z
    Publisher Deneysel, Biyoteknolojik, Klinik ve Stratejik Sağlık Araştırmaları Derneği
    Publishing country tr
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The Relationship Between Health Literacy Level and Media Used as a Source of Health-Related Information.

    Özkan, Seçil / Tüzün, Hakan / Dikmen, Asiye Uğraş / Aksakal, Nur Baran / Çalışkan, Deniz / Taşçı, Özge / Güneş, Selime Ceylan

    Health literacy research and practice

    2021  Volume 5, Issue 2, Page(s) e109–e117

    Abstract: Background: Previous studies have not shown the level of health literacy or associated factors on a national level in Turkey using a scale that has been adapted to the country and its culture.: Objective: This study aimed to determine health literacy ...

    Abstract Background: Previous studies have not shown the level of health literacy or associated factors on a national level in Turkey using a scale that has been adapted to the country and its culture.
    Objective: This study aimed to determine health literacy levels in Turkey and to investigate the association of health literacy with socioeconomic factors as well as with the instruments used as sources of health-related information.
    Methods: This cross-sectional, nationally representative study was conducted using a computer-assisted personal interview approach and included 6,228 households (response rate, 70.9%). The Turkey Health Literacy Scale was used to measure health literacy. Sources of health-related information, such as newspapers, television, internet, and smartphones, were included in the regression model for health literacy.
    Key results: The proportion of participants with inadequate and problematic health literacy was 30.9% and 38%, respectively, showing that approximately 7 of 10 participants had limited health literacy. The frequencies of inadequate and problematic health literacy were higher in the disease prevention and promotion domains (37.4% and 34.2%, respectively) compared with those in the health care domain (27.1% and 31.3%, respectively). The most frequently used medium as a source of health-related information was the internet (48.6%), followed by television (33%). In controlled models, higher health literacy scores were associated with higher education and income levels. The effects of television (β = 1,917), internet (β = 2,803), newspapers (β = 1,489), and smartphones (β = 1,974) as sources of health-related information were statistically significant in the general health literacy index model.
    Conclusions: Health literacy in Turkey reflects social inequalities. The model accounting for socioeconomic variables demonstrated the relevance of sources of health information to level of health literacy. These findings emphasize the importance of improving sources of health information to improve health literacy.
    MeSH term(s) Cross-Sectional Studies ; Health Literacy ; Humans ; Socioeconomic Factors ; Surveys and Questionnaires
    Language English
    Publishing date 2021-05-10
    Publishing country United States
    Document type Journal Article
    ISSN 2474-8307
    ISSN (online) 2474-8307
    DOI 10.3928/24748307-20210330-01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: HIV Pozitifliği Gerçek Zamanlı RT-PCR ile Takip Edilen Hastaların HTLV-I/II Seroprevalansının Araştırılması.

    Şahin, Erdem / Sarzhanova, Shakhnoza / Çuhadar Uysal, Burcu / Yıldız, Şeyma / Hızel, Kenan / Özkan, Seçil / Fidan, Işıl / Bozdayı, Gülendam

    Mikrobiyoloji bulteni

    2021  Volume 55, Issue 3, Page(s) 426–434

    Abstract: Human T-lymphotropic virus-I/II (HTLV-I/II) and human immun viruses (HIVs), that have similar genomic characteristics also share the same transmission routes and infect T lymphocytes. Regarding this epidemiological similarity, HIV and HTLV infections can ...

    Title translation Investigation of HTLV-I/II Seroprevalance of Patients with HIV Positivity being Monitored by Real-Time RT-PCR.
    Abstract Human T-lymphotropic virus-I/II (HTLV-I/II) and human immun viruses (HIVs), that have similar genomic characteristics also share the same transmission routes and infect T lymphocytes. Regarding this epidemiological similarity, HIV and HTLV infections can be seen together. HIV and HTLV-I/II coinfection occurs with variable frequencies in different populations and geographic regions. There are not any population-based studies carried out defining the number of individuals coinfected with HIV and HTLV-I/II in Turkey. The aim of this study was to determine the seropositivity rates of HTLV-I/II in patients whose HIV viral load was monitored in Gazi University Faculty of Medicine Medical Virology Laboratory Forty-seven HIV positive cases followed-up in Medical Virology Laboratory for HIV viral load monitoring between May 2017-January 2019 were included in the study. HIV seropositivity of the samples was confirmed by the chemiluminescence microparticle immunoassay method. HIV viral load values of the samples were evaluated by real-time reverse transcriptase polymerase chain reaction. The samples were screened for antibodies against HTLV-I/II using chemiluminescent microparticle immunoassay. The study population range was between 19 to 60 years of age. Among the study population, 39 (83%) patients were male and 8 (17%) patients were female. Of 47 samples, 18 samples (38.3%) had viral load of <1000 copies/ml, 10 samples (21.3%) had viral load of 1000-10000 copies/ml, 19 samples (40.4%) had viral load of ≥10000 copies/ml. HTLV serology was negative in all samples included in the study. CD4+ results were available for 42 patients and the CD4+ results of five patients could not be studied. Co-infection with different retroviruses is a well-known fact which should be thoroughly examined. HTLV-I co-infection leads to faster progression of the disease in HIV-1 positive patients. Although it is known that the co-infection has a significant effect on the progression of the disease, there are very few centers in the world and in our country that routinely perform HTLV testing in HIV-positive patients. We think that in order to evaluate the clinical and microbiological importance of the coinfection of retroviruses with each other and to determine the frequency of these infections together, there is a need for studies involving a larger number of patients, including detailed clinical backgrounds of individuals, and that the importance of this issue should be realized at the same time.
    MeSH term(s) Female ; HIV Infections/complications ; HIV Infections/epidemiology ; HIV-1/genetics ; Human T-lymphotropic virus 1/genetics ; Human T-lymphotropic virus 2/genetics ; Humans ; Male ; Reverse Transcriptase Polymerase Chain Reaction
    Language Turkish
    Publishing date 2021-08-20
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 985146-x
    ISSN 0374-9096
    ISSN 0374-9096
    DOI 10.5578/mb.20219811
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Detection of HPV DNA in Esophageal Lesions: a Cross-Sectional Study.

    Dinc, Bedia / Altay-Kocak, Aylin / Aydog, Gulden / Kuran, Sedef / Akoglu, Musa / Ozkan, Secil / Bozdayi, Gulendam

    Clinical laboratory

    2020  Volume 66, Issue 3

    Abstract: Background: Several studies have documented human papillomavirus (HPV) in extra-cervical tumors. We aimed to detect HPV type 16 and HPV other than type 16 (OT-16) DNA in esophageal papilloma and esophagus squamous cell carcinoma (ESCC) samples and to ... ...

    Abstract Background: Several studies have documented human papillomavirus (HPV) in extra-cervical tumors. We aimed to detect HPV type 16 and HPV other than type 16 (OT-16) DNA in esophageal papilloma and esophagus squamous cell carcinoma (ESCC) samples and to compare clinicopathological features of HPV positive and negative patients.
    Methods: Materials were obtained from a tertiary care public hospital and studied in an university hospital for this cross-sectional study. Seventy-six tissue samples (50 papilloma and 26 ESCC) were included. After deparaffinization by xylene and DNA extraction by phenol chloroform-isoamyl-alcohol, 76 samples were studied with a G6PDH control kit. Forty-four papilloma and 21 ESCC samples with enough tissues were studied for HPV DNA. HPV OT-16 DNA and HPV type 16 were detected by real time-polymerase chain reaction.
    Results: Twelve (27.3%) and one (2.3%) of the papilloma samples were HPV type 16 and other than type 16 positive, respectively. Eleven (52.4%) and one (4.8%) of ESCC samples were HPV type 16 and mixed type positive, respectively.
    Conclusions: We suggest that HPV infection is common in esophageal papilloma and ESCC. Due to the wellknown association of HPV with premalignant and malignant conditions, follow-up of these patients accompanied by HPV should be implemented.
    MeSH term(s) Adult ; Aged ; Cross-Sectional Studies ; DNA, Viral/analysis ; DNA, Viral/isolation & purification ; Esophageal Neoplasms/epidemiology ; Esophageal Neoplasms/virology ; Esophageal Squamous Cell Carcinoma/epidemiology ; Esophageal Squamous Cell Carcinoma/virology ; Female ; Human papillomavirus 16/genetics ; Humans ; Male ; Middle Aged ; Papillomaviridae/genetics ; Papillomavirus Infections/complications ; Papillomavirus Infections/epidemiology ; Papillomavirus Infections/virology ; Retrospective Studies ; Young Adult
    Chemical Substances DNA, Viral
    Language English
    Publishing date 2020-03-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1307629-2
    ISSN 1433-6510 ; 0941-2131
    ISSN 1433-6510 ; 0941-2131
    DOI 10.7754/Clin.Lab.2019.190506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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