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  1. Article: Post-COVID changes in lung function 6 months after veno-venous extracorporeal membrane oxygenation: a prospective observational clinical trial.

    Pálfi, Alexandra / Balogh, Ádám L / Polónyi, Gabriella / Schulcz, Domonkos / Zöllei, Éva / Bari, Gábor / Fodor, Gergely H / Baráth, Kristóf / Somfay, Attila / Peták, Ferenc / Babik, Barna

    Frontiers in medicine

    2023  Volume 10, Page(s) 1288679

    Abstract: Background: Severe coronavirus disease 2019 (COVID-19) may require veno-venous extracorporeal membrane oxygenation (V-V ECMO). While V-V ECMO is offered in severe lung injury to COVID-19, long-term respiratory follow-up in these patients is missing. ... ...

    Abstract Background: Severe coronavirus disease 2019 (COVID-19) may require veno-venous extracorporeal membrane oxygenation (V-V ECMO). While V-V ECMO is offered in severe lung injury to COVID-19, long-term respiratory follow-up in these patients is missing. Therefore, we aimed at providing comprehensive data on the long-term respiratory effects of COVID-19 requiring V-V ECMO support during the acute phase of infection.
    Methods: In prospective observational cohort study design, patients with severe COVID-19 receiving invasive mechanical ventilation and V-V ECMO (COVID group,
    Results: The COVID group had a higher AX
    Conclusion: Severe acute COVID-19 requiring V-V ECMO persistently impairs small airway function and reduces respiratory tissue elasticity, primarily attributed to lung restriction. These findings also suggest that even severe pulmonary pathologies of acute COVID-19 can manifest in a moderate but still persistent lung function impairment 6 months after hospital discharge.
    Trial registration: NCT05812196.
    Language English
    Publishing date 2023-12-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1288679
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Venovenous extracorporeal membrane oxygenation for COVID-19 associated severe respiratory failure: Case series from a Hungarian tertiary centre.

    Zöllei, Éva / Rudas, László / Hankovszky, Péter / Korsós, Anita / Pálfi, Alexandra / Varga, Zoltán / Tomozi, László / Hegedüs, Zoltán / Bari, Gábor / Lobozárné Szivós, Brigitta / Kiszel, Attila / Babik, Barna

    Perfusion

    2023  Volume 39, Issue 4, Page(s) 790–796

    Abstract: Introduction: Venovenous extracorporeal membrane oxygenation (V-V ECMO) is recommended for the support of patients with severe COVID-19 associated severe respiratory failure (SRF). We report the characteristics and outcome of COVID-19 patients supported ...

    Abstract Introduction: Venovenous extracorporeal membrane oxygenation (V-V ECMO) is recommended for the support of patients with severe COVID-19 associated severe respiratory failure (SRF). We report the characteristics and outcome of COVID-19 patients supported with V-V ECMO in a Hungarian centre.
    Methods: We retrospectively collected data on all patients admitted with proven SARS CoV-2 infection who received V-V ECMO support between March 2021 and May 2022.
    Results: Eighteen patients were placed on ECMO during this period, (5 women, age (mean ± SD) 44 ± 10 years, APACHE II score (median (interquartile range)) 12 (10-14.5)). Before ECMO support, they had been hospitalised for 6 (4-11) days. Fifteen patients received noninvasive ventilation for 4 (2-8) days, two patients had high flow nasal oxygen therapy, for one day each. They had already been intubated for 2.5 (1-6) days. Prone position was applied in 15 cases. On the day before ECMO initiation the Lung Injury Score was 3.25 (3-3.26), the PaO
    Conclusions: During the last three waves of the COVID-19 pandemic, we achieved a 56% ICU and a 50% hospital survival rate at our low volume centre.
    MeSH term(s) Humans ; Extracorporeal Membrane Oxygenation/methods ; COVID-19/therapy ; COVID-19/complications ; COVID-19/mortality ; Female ; Male ; Adult ; Retrospective Studies ; Middle Aged ; Hungary ; Respiratory Insufficiency/therapy ; SARS-CoV-2 ; Tertiary Care Centers ; Treatment Outcome
    Language English
    Publishing date 2023-03-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 645038-6
    ISSN 1477-111X ; 0267-6591
    ISSN (online) 1477-111X
    ISSN 0267-6591
    DOI 10.1177/02676591231160272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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