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Article ; Online: Growth hormone treatment in small for gestational age children. A single-center experience

Ariza Jiménez, Ana B / Pérez García, Cristina / De la Cámara Moraño, Carmen

2023 Volume 121, Issue 4, Page(s) e202202753

Abstract: Introduction. Small for gestational age (SGA) children usually have a final height of 1 SD below the mean. Three groups are established based on anthropometric characteristics at birth: low birth weight (LBW), short birth length (SBL), or both. ... ...

Title translation	Tratamiento con hormona de crecimiento en niños nacidos pequeños para la edad gestacional. Experiencia de un centro.
Abstract	Introduction. Small for gestational age (SGA) children usually have a final height of 1 SD below the mean. Three groups are established based on anthropometric characteristics at birth: low birth weight (LBW), short birth length (SBL), or both. Objectives. To describe the characteristics of SGA patients seen at the Department of Pediatric Endocrinology of a tertiary care hospital and to analyze the course of SGA children without catch-up growth at 4 years of age who were receiving treatment with growth hormone (GH), according to their diagnosis. Methods. Retrospective study of SGA patients seen between 2004 and 2021. Results. A total of 89 SGA children were studied; 44/89 started treatment with GH (11/44 LBW, 8/44 SBL, and 25/44 both). Their mean age at diagnosis was 3.87 years; their mean height at treatment initiation was -2.99 SD in SGA children diagnosed by LBW, -2.85 SD in those with SBL, and -3.17 SD in those with both LBW and SBL. Their final height was -1.77, -1.52, and -1.23 SD, respectively, with a total gain of 1.22, 1.33, and 1.93 SD, respectively, thus reaching their target height with a difference of 0.36 ± 0.08 SD. Conclusion. Less than half of SGA children referred to the clinic required treatment with GH because they were not yet 4 years old or had not completed their catch-up growth. SGA patients according to birth weight and length had worse percentiles at diagnosis and a greater response to GH.
MeSH term(s)	Infant, Newborn ; Humans ; Child ; Child, Preschool ; Retrospective Studies ; Gestational Age ; Body Height ; Human Growth Hormone/therapeutic use ; Growth Hormone
Chemical Substances	Human Growth Hormone (12629-01-5) ; Growth Hormone (9002-72-6)
Language	Spanish
Publishing date	2023-03-02
Publishing country	Argentina
Document type	Journal Article
ZDB-ID	424449-7
ISSN	1668-3501 ; 0325-0075 ; 0004-0487
ISSN (online)	1668-3501
ISSN	0325-0075 ; 0004-0487
DOI	10.5546/aap.2022-02753.eng
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Article ; Online: Importancia de la anamnesis exhaustiva ante una ginecomastia unilateral inexplicada en un niño.

Pérez-García, Cristina / Ariza Jiménez, Ana B / Camacho Lozano, Laura / de la Cámara Moraño, Carmen

Archivos argentinos de pediatria

2018 Volume 116, Issue 5, Page(s) e655–e658

Abstract: Gynecomastia consists of breast enlargement due to a hormonal imbalance between estrogens and androgens. Unilateral and important breast growth requires ruling underlying pathologic disorders out. Mechanical cause is uncommon, causing enlargement by ... ...

Title translation	Importance of the exhaustive anamnesis to an unexplained unilateral gynecomastia in a child.
Abstract	Gynecomastia consists of breast enlargement due to a hormonal imbalance between estrogens and androgens. Unilateral and important breast growth requires ruling underlying pathologic disorders out. Mechanical cause is uncommon, causing enlargement by repeated stimulation. We report a 6-year-old boy with unilateral gynecomastia. Hyperprolactinemia is the only abnormal finding at laboratory tests. After repeated inquiries, a continuous breast selfstimulation is detected. Its relation with gynecomastia is verified because prolactin normalizes and breast regressed in further revisions, after stopping stimulus.
MeSH term(s)	Child ; Gynecomastia/diagnosis ; Gynecomastia/etiology ; Humans ; Hyperprolactinemia/diagnosis ; Hyperprolactinemia/etiology ; Male ; Prolactin/blood
Chemical Substances	Prolactin (9002-62-4)
Language	Spanish
Publishing date	2018-09-08
Publishing country	Argentina
Document type	Case Reports ; Journal Article
ZDB-ID	424449-7
ISSN	1668-3501 ; 0325-0075 ; 0004-0487
ISSN (online)	1668-3501
ISSN	0325-0075 ; 0004-0487
DOI	10.5546/aap.2018.e655
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Article ; Online: Clusters of inflammation in COVID-19: descriptive analysis and prognosis on more than 15,000 patients from the Spanish SEMI-COVID-19 Registry.

Rubio-Rivas, Manuel / Mora-Luján, José María / Formiga, Francesc / Corrales González, Miguel Ángel / García Andreu, María Del Mar / Moreno-Torres, Víctor / García García, Gema María / Alcalá Pedrajas, José N / Boixeda, Ramon / Pérez-Lluna, Leticia / Cortés-Rodríguez, Begoña / Mella-Pérez, Carmen / Navas Alcántara, María de la Sierra / López Reboiro, Manuel Lorenzo / Alfaro-Lara, Verónica / Pérez-Martín, Santiago / Martín-Oterino, José Ángel / Gracia Gutiérrez, Anyuli / Martín-Urda Díez-Canseco, Anabel /

Comas Casanova, Pere / Pérez García, Cristina / Varona, José F / Gómez-Huelgas, Ricardo / Antón-Santos, Juan-Miguel / Lumbreras-Bermejo, Carlos

Internal and emergency medicine

2022 Volume 17, Issue 4, Page(s) 1115–1127

Abstract: Uncontrolled inflammation following COVID-19 infection is an important characteristic of the most seriously ill patients. The present study aims to describe the clusters of inflammation in COVID-19 and to analyze their prognostic role. This is a ... ...

Abstract	Uncontrolled inflammation following COVID-19 infection is an important characteristic of the most seriously ill patients. The present study aims to describe the clusters of inflammation in COVID-19 and to analyze their prognostic role. This is a retrospective observational study including 15,691 patients with a high degree of inflammation. They were included in the Spanish SEMI-COVID-19 registry from March 1, 2020 to May 1, 2021. The primary outcome was in-hospital mortality. Hierarchical cluster analysis identified 7 clusters. C1 is characterized by lymphopenia, C2 by elevated ferritin, and C3 by elevated LDH. C4 is characterized by lymphopenia plus elevated CRP and LDH and frequently also ferritin. C5 is defined by elevated CRP, and C6 by elevated ferritin and D-dimer, and frequently also elevated CRP and LDH. Finally, C7 is characterized by an elevated D-dimer. The clusters with the highest in-hospital mortality were C4, C6, and C7 (17.4% vs. 18% vs. 15.6% vs. 36.8% vs. 17.5% vs. 39.3% vs. 26.4%). Inflammation clusters were found as independent factors for in-hospital mortality. In detail and, having cluster C1 as reference, the model revealed a worse prognosis for all other clusters: C2 (OR = 1.30, p = 0.001), C3 (OR = 1.14, p = 0.178), C4 (OR = 2.28, p < 0.001), C5 (OR = 1.07, p = 0.479), C6 (OR = 2.29, p < 0.001), and C7 (OR = 1.28, p = 0.001). We identified 7 groups based on the presence of lymphopenia, elevated CRP, LDH, ferritin, and D-dimer at the time of hospital admission for COVID-19. Clusters C4 (lymphopenia + LDH + CRP), C6 (ferritin + D-dimer), and C7 (D-dimer) had the worst prognosis in terms of in-hospital mortality.
MeSH term(s)	Biomarkers ; COVID-19/complications ; Ferritins ; Humans ; Inflammation ; Lymphopenia ; Prognosis ; Registries ; Retrospective Studies ; SARS-CoV-2
Chemical Substances	Biomarkers ; Ferritins (9007-73-2)
Language	English
Publishing date	2022-03-02
Publishing country	Italy
Document type	Journal Article ; Observational Study
ZDB-ID	2454173-4
ISSN	1970-9366 ; 1828-0447
ISSN (online)	1970-9366
ISSN	1828-0447
DOI	10.1007/s11739-021-02924-4
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Article ; Online: Estimated fetal weight percentile as a tool to predict collection of cord blood units with higher cellular content: implications for prenatal selection of cord blood donors.

Lin, Xinxin / Torrabadella, Marta / Amat, Lluís / Gómez, Susana / Azqueta, Carmen / Sánchez, Mar / Cuadras, Daniel / Martínez Lorenzo, Maria José / Brull, José María / Gayà, Antoni / Cemborain, Arantxa / Pérez Garcia, Cristina / Arroyo, JoséLuís / Querol, Sergi / Gómez Roig, Maria Dolores

Transfusion

2018 Volume 58, Issue 7, Page(s) 1732–1738

Abstract: Background: The need for high-cellular-content cord blood units (CBUs) for allogenic transplantation is evident to improve clinical outcomes. In our environment and with current donation programs, very few collected units meet suggested clinical ... ...

Abstract	Background: The need for high-cellular-content cord blood units (CBUs) for allogenic transplantation is evident to improve clinical outcomes. In our environment and with current donation programs, very few collected units meet suggested clinical thresholds, making collection programs highly inefficient. To increase the clinical conversion rate, we have assessed factors influencing the cellular content of the cord blood collection and established the estimated fetal weight percentile (EFWp) as a tool to predict which deliveries will obtain higher cellular counts. Study design and methods: We conducted a retrospective analysis of 11,349 collected CBUs. An analysis of diagnostic efficiency (receiver operating characteristic [ROC] curve) was performed to establish the cutoffs of several obstetric and perinatal variables from which we would obtain more than 1500 × 10 Results: In the univariate analysis, factors positively and significantly associated were a greater neonatal and placental weight and longer weeks of gestation. In the multivariate analysis only neonatal and placental weight remain significant (p < 0.001). The ROC curve analysis showed that the optimal EFWp cutoff is 60, which has the maximum area under the curve. Applying this, donations meeting clinical cellular numbers will increase more than 30% with respect to not using any threshold. Conclusion: The EFWp predicts the quality of the collected CBUs and can be used to make a prenatal selection of the donors, therefore increasing the efficiency of umbilical cord blood collection programs.
MeSH term(s)	Blood Banking/methods ; Blood Donors ; Blood Specimen Collection/methods ; Female ; Fetal Blood/cytology ; Fetal Weight ; Humans ; Infant, Newborn ; Male ; Pregnancy ; Retrospective Studies
Language	English
Publishing date	2018-05-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	208417-x
ISSN	1537-2995 ; 0041-1132
ISSN (online)	1537-2995
ISSN	0041-1132
DOI	10.1111/trf.14651
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Article ; Online: The Use of Corticosteroids or Tocilizumab in COVID-19 Based on Inflammatory Markers.

Rubio-Rivas, Manuel / Mora-Luján, José M / Montero, Abelardo / Aguilar García, Josefa Andrea / Méndez Bailón, Manuel / Fernández Cruz, Ana / Oriol, Isabel / Teigell-Muñoz, Francisco-Javier / Dendariena Borque, Beatriz / De la Peña Fernández, Andrés / Fernández González, Raquel / Gil Sánchez, Ricardo / Fernández Fernández, Javier / Catalán, Marta / Cortés-Rodríguez, Begoña / Mella Pérez, Carmen / Montero Rivas, Lorena / Suárez Fuentetaja, Rebeca / Ternero Vega, Jara Eloísa /

Ena, Javier / Martin-Urda Díez-Canseco, Anabel / Pérez García, Cristina / Varona, José F / Casas-Rojo, José Manuel / Millán Núñez-Cortés, Jesús

Journal of general internal medicine

2021 Volume 37, Issue 1, Page(s) 168–175

Abstract: Background: The inflammatory cascade is the main cause of death in COVID-19 patients. Corticosteroids (CS) and tocilizumab (TCZ) are available to treat this escalation but which patients to administer it remains undefined.: Objective: We aimed to ... ...

Abstract	Background: The inflammatory cascade is the main cause of death in COVID-19 patients. Corticosteroids (CS) and tocilizumab (TCZ) are available to treat this escalation but which patients to administer it remains undefined. Objective: We aimed to evaluate the efficacy of immunosuppressive/anti-inflammatory therapy in COVID-19, based on the degree of inflammation. Design: A retrospective cohort study with data on patients collected and followed up from March 1st, 2020, to May 1st, 2021, from the nationwide Spanish SEMI-COVID-19 Registry. Patients under treatment with CS vs. those under CS plus TCZ were compared. Effectiveness was explored in 3 risk categories (low, intermediate, high) based on lymphocyte count, C-reactive protein (CRP), lactate dehydrogenase (LDH), ferritin, and D-dimer values. Patients: A total of 21,962 patients were included in the Registry by May 2021. Of these, 5940 met the inclusion criteria for the present study (5332 were treated with CS and 608 with CS plus TCZ). Main measures: The primary outcome of the study was in-hospital mortality. Secondary outcomes were the composite variable of in-hospital mortality, requirement for high-flow nasal cannula (HFNC), non-invasive mechanical ventilation (NIMV), invasive mechanical ventilation (IMV), or intensive care unit (ICU) admission. Key results: A total of 5940 met the inclusion criteria for the present study (5332 were treated with CS and 608 with CS plus TCZ). No significant differences were observed in either the low/intermediate-risk category (1.5% vs. 7.4%, p=0.175) or the high-risk category (23.1% vs. 20%, p=0.223) after propensity score matching. A statistically significant lower mortality was observed in the very high-risk category (31.9% vs. 23.9%, p=0.049). Conclusions: The prescription of CS alone or in combination with TCZ should be based on the degrees of inflammation and reserve the CS plus TCZ combination for patients at high and especially very high risk.
MeSH term(s)	Adrenal Cortex Hormones/therapeutic use ; Antibodies, Monoclonal, Humanized/therapeutic use ; Biomarkers ; Humans ; Inflammation ; Retrospective Studies ; SARS-CoV-2 ; COVID-19 Drug Treatment
Chemical Substances	Adrenal Cortex Hormones ; Antibodies, Monoclonal, Humanized ; Biomarkers ; tocilizumab (I031V2H011)
Language	English
Publishing date	2021-10-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	639008-0
ISSN	1525-1497 ; 0884-8734
ISSN (online)	1525-1497
ISSN	0884-8734
DOI	10.1007/s11606-021-07146-0
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Article ; Online: Clinical Characteristics and Risk Factors for Mortality in Very Old Patients Hospitalized With COVID-19 in Spain.

Ramos-Rincon, Jose-Manuel / Buonaiuto, Verónica / Ricci, Michele / Martín-Carmona, Jesica / Paredes-Ruíz, Diana / Calderón-Moreno, María / Rubio-Rivas, Manel / Beato-Pérez, José-Luis / Arnalich-Fernández, Francisco / Monge-Monge, Daniel / Vargas-Núñez, Juan-Antonio / Acebes-Repiso, Gonzalo / Mendez-Bailon, Manuel / Perales-Fraile, Isabel / García-García, Gema-María / Guisado-Vasco, Pablo / Abdelhady-Kishta, Alaaeldeen / Pascual-Pérez, Maria-de-Los-Reyes / Rodríguez-Fernández-Viagas, Cristina /

Montaño-Martínez, Adrián / López-Ruiz, Antonio / Gonzalez-Juarez, Maria-Jesus / Pérez-García, Cristina / Casas-Rojo, José-Manuel / Gómez-Huelgas, Ricardo

The journals of gerontology. Series A, Biological sciences and medical sciences

2020 Volume 76, Issue 3, Page(s) e28–e37

Abstract: Background: Advanced age is a well-known risk factor for poor prognosis in COVID-19. However, few studies have specifically focused on very old inpatients with COVID-19. This study aims to describe the clinical characteristics of very old inpatients ... ...

Abstract	Background: Advanced age is a well-known risk factor for poor prognosis in COVID-19. However, few studies have specifically focused on very old inpatients with COVID-19. This study aims to describe the clinical characteristics of very old inpatients with COVID-19 and identify risk factors for in-hospital mortality at admission. Methods: We conducted a nationwide, multicenter, retrospective, observational study in patients ≥ 80 years hospitalized with COVID-19 in 150 Spanish hospitals (SEMI-COVID-19) Registry (March 1-May 29, 2020). The primary outcome was in-hospital mortality. A uni- and multivariate logistic regression was performed to assess predictors of mortality at admission. Results: A total of 2772 consecutive patients (49.4% men, median age 86.3 years) were analyzed. Rates of atherosclerotic cardiovascular disease, diabetes mellitus, dementia, and Barthel Index < 60 were 30.8%, 25.6%, 30.5%, and 21.0%, respectively. The overall case-fatality rate was 46.9% (n: 1301) and increased with age (80-84 years: 41.6%; 85-90 years: 47.3%; 90-94 years: 52.7%; ≥95 years: 54.2%). After analysis, male sex and moderate-to-severe dependence were independently associated with in-hospital mortality; comorbidities were not predictive. At admission, independent risk factors for death were: oxygen saturation < 90%; temperature ≥ 37.8°C; quick sequential organ failure assessment (qSOFA) score ≥ 2; and unilateral-bilateral infiltrates on chest x-rays. Some analytical findings were independent risk factors for death, including estimated glomerular filtration rate < 45 mL/min/1.73 m2; lactate dehydrogenase ≥ 500 U/L; C-reactive protein ≥ 80 mg/L; neutrophils ≥ 7.5 × 103/μL; lymphocytes < 0.8 × 103/μL; and monocytes < 0.5 × 103/μL. Conclusions: This first large, multicenter cohort of very old inpatients with COVID-19 shows that age, male sex, and poor preadmission functional status-not comorbidities-are independently associated with in-hospital mortality. Severe COVID-19 at admission is related to poor prognosis.
MeSH term(s)	Aged, 80 and over ; COVID-19/epidemiology ; COVID-19/mortality ; COVID-19/therapy ; Female ; Hospital Mortality ; Hospitalization ; Humans ; Male ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/therapy ; Prognosis ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Spain/epidemiology
Keywords	covid19
Language	English
Publishing date	2020-10-26
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Observational Study
ZDB-ID	1223643-3
ISSN	1758-535X ; 1079-5006
ISSN (online)	1758-535X
ISSN	1079-5006
DOI	10.1093/gerona/glaa243
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Article: Clinical Characteristics and Risk Factors for Mortality in Very Old Patients Hospitalized with COVID-19 in Spain

Montaño-Martínez, Adrián / López-Ruiz, Antonio / Gonzalez-Juarez, Maria-Jesus / Pérez-García, Cristina / Casas-Rojo, José-Manuel / Gómez-Huelgas, Ricardo

J. gerontol. Ser. A, Biol. sci. med. sci

Abstract: BACKGROUND: Advanced age is a well-known risk factor for poor prognosis in COVID-19. However, few studies have specifically focused on very old inpatients with COVID-19. This study aims to describe the clinical characteristics of very old inpatients with ...

Abstract	BACKGROUND: Advanced age is a well-known risk factor for poor prognosis in COVID-19. However, few studies have specifically focused on very old inpatients with COVID-19. This study aims to describe the clinical characteristics of very old inpatients with COVID-19 and identify risk factors for in-hospital mortality at admission. METHODS: We conducted a nationwide, multicenter, retrospective, observational study in patients ≥80 years hospitalized with COVID-19 in 150 Spanish hospitals (SEMI-COVID-19) Registry (March 1-May 29, 2020). The primary outcome was in-hospital mortality. A uni- and multivariate logistic regression was performed to assess predictors of mortality at admission. RESULTS: 2,772 consecutive patients (49.4% men, median age 86.3 years) were analyzed. Rates of atherosclerotic cardiovascular disease, diabetes mellitus, dementia, and Barthel Index <60 were 30.8%, 25.6%, 30.5%, and 21.0%, respectively. The overall case-fatality rate was 46.9% (n:1,301) and increased with age (80-84 years:41.6%; 85-90 years:47.3%; 90-94 years:52.7%; ≥95 years:54.2%). After analysis, male sex and moderate-to-severe dependence were independently associated with in-hospital mortality; comorbidities were not predictive. At admission, independent risk factors for death were: SatO2 <90%; temperature ≥37.8ºC; qSOFA score ≥2; and unilateral-bilateral infiltrates on chest X-rays. Some analytical findings were independent risk factors for death, including eGFR <45 ml/min/1.73m 2; lactate dehydrogenase ≥500 U/L; CRP ≥80 mg/L; neutrophils ≥7.5x10 3/µL; lymphocytes <0.8x10 3/µL; and monocytes <0.5 x 10 3/µL. CONCLUSIONS: This first large, multicenter cohort of very old inpatients with COVID-19 shows that age, male sex, and poor pre-admission functional status-not comorbidities-are independently associated with in-hospital mortality. Severe COVID-19 at admission is related to poor prognosis.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #889546
Database	COVID19

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Article ; Online: Clinical Characteristics and Risk Factors for Mortality in Very Old Patients Hospitalized With COVID-19 in Spain

Ramos-Rincon, Jose-Manuel / Buonaiuto, Verónica / Ricci, Michele / Martín-Carmona, Jesica / Paredes-Ruíz, Diana / Calderón-Moreno, María / Rubio-Rivas, Manel / Beato-Pérez, José-Luis / Arnalich-Fernández, Francisco / Monge-Monge, Daniel / Vargas-Núñez, Juan-Antonio / Acebes-Repiso, Gonzalo / Mendez-Bailon, Manuel / Perales-Fraile, Isabel / García-García, Gema-María / Guisado-Vasco, Pablo / Abdelhady-Kishta, Alaaeldeen / Pascual-Pérez, Maria-de-los-Reyes / Rodríguez-Fernández-Viagas, Cristina /

Montaño-Martínez, Adrián / López-Ruiz, Antonio / Gonzalez-Juarez, Maria-Jesus / Pérez-García, Cristina / Casas-Rojo, José-Manuel / Gómez-Huelgas, Ricardo

The Journals of Gerontology: Series A ; ISSN 1079-5006 1758-535X

2020

Abstract: Abstract Background Advanced age is a well-known risk factor for poor prognosis in COVID-19. However, few studies have specifically focused on very old inpatients with COVID-19. This study aims to describe the clinical characteristics of very old ... ...

Abstract	Abstract Background Advanced age is a well-known risk factor for poor prognosis in COVID-19. However, few studies have specifically focused on very old inpatients with COVID-19. This study aims to describe the clinical characteristics of very old inpatients with COVID-19 and identify risk factors for in-hospital mortality at admission. Methods We conducted a nationwide, multicenter, retrospective, observational study in patients ≥ 80 years hospitalized with COVID-19 in 150 Spanish hospitals (SEMI-COVID-19) Registry (March 1–May 29, 2020). The primary outcome was in-hospital mortality. A uni- and multivariate logistic regression was performed to assess predictors of mortality at admission. Results A total of 2772 consecutive patients (49.4% men, median age 86.3 years) were analyzed. Rates of atherosclerotic cardiovascular disease, diabetes mellitus, dementia, and Barthel Index < 60 were 30.8%, 25.6%, 30.5%, and 21.0%, respectively. The overall case-fatality rate was 46.9% (n: 1301) and increased with age (80–84 years: 41.6%; 85–90 years: 47.3%; 90–94 years: 52.7%; ≥95 years: 54.2%). After analysis, male sex and moderate-to-severe dependence were independently associated with in-hospital mortality; comorbidities were not predictive. At admission, independent risk factors for death were: oxygen saturation < 90%; temperature ≥ 37.8°C; quick sequential organ failure assessment (qSOFA) score ≥ 2; and unilateral–bilateral infiltrates on chest x-rays. Some analytical findings were independent risk factors for death, including estimated glomerular filtration rate < 45 mL/min/1.73 m2; lactate dehydrogenase ≥ 500 U/L; C-reactive protein ≥ 80 mg/L; neutrophils ≥ 7.5 × 103/μL; lymphocytes < 0.8 × 103/μL; and monocytes < 0.5 × 103/μL. Conclusions This first large, multicenter cohort of very old inpatients with COVID-19 shows that age, male sex, and poor preadmission functional status—not comorbidities—are independently associated with in-hospital mortality. Severe COVID-19 at admission is related to poor prognosis.
Keywords	Ageing ; Geriatrics and Gerontology ; covid19
Language	English
Publisher	Oxford University Press (OUP)
Publishing country	uk
Document type	Article ; Online
DOI	10.1093/gerona/glaa243
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Article ; Online: Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state

Rodríguez-Baño, Jesús / Pachón, Jerónimo / Carratalà, Jordi / Ryan, Pablo / Jarrín, Inmaculada / Yllescas, María / Arribas, José Ramón / Berenguer, Juan / Aznar Muñoz, Esther / Gil Divasson, Pedro / González Muñiz, Patricia / Muñoz Aguirre, Clara / Díaz Menéndez, Marta / de la Calle Prieto, Fernando / Arsuaga Vicente, Marta / Trigo Esteban, Elena / Pérez Valero, Ignacio / de Miguel Buckley, Rosa / Cadiñaños Loidi, Julen /

Diaz Pollan, Beatriz / Martín Carbonero, Luz / Ramos Ramos, Juan Carlos / Loeches Yagüe, Belén / Montejano Sánchez, Rocío / González García, Juan / García Rodríguez, Julio / Ramírez, Margarita / Gutiérrez, Isabel / Tejerina, Francisco / Aldámiz-Echevarría, Teresa / Díez, Cristina / Fanciulli, Chiara / Pérez-Latorre, Leire / Pinilla, Blanca / López, Juan Carlos / Such Diaz, Ana / Álvaro Alonso, Elena / Torres Macho, Juan / Cuevas Tascon, Guillermo / Jiménez González de Buitrago, Eva / Brañas Baztán, Fátima / Valencia de la Rosa, Jorge / Pérez Butragueño, Mario / Fernández Jiménez, Inés / Muñiz Nicolás, Gemma / Sepúlveda Berrocal, Antonia / Gato Díez, Alberto / Toledano Sierra, María Pilar / García Butenegro, María Paz / Peláez Ballesta, Ana Isabel / Morcillo Rodríguez, Elena / Fernández Romero, Isidoro / Peláez Ballesta, Cristina / Guirado Torrecillas, María Isabel / Goikoetxea Agirre, Josune / Bereciartua Bastarrica, Elena / Guio Carrión, Laura / Rodríguez Álvarez, Regino / Ibarrola Hierro, Marta / Pérez Hernández, Isabel A. / Pérez Zapata, Inés / Román Soto, Sergio / Kallouchi, Mohamed / Domínguez Vicent, Juan Ramón / Silvariño Fernández, Rafae / Ugalde Espiñeira, Jon / Sanjuan López, Ainhoa / García Martínez, Silvia / Temprano Gogenola, Mikel / Asensi, Víctor / Suárez, Silvia / Suárez, Lucia / Yllera, Carmen / Rivas-Carmenado, María / Romero-Palacios, Alberto / Ruiz Aragón, Jesús / Jiménez Aguilar, Patricia / Fernández Ávila, Ma Luisa / Castilla Ortiz, Rosario / Alende Castro, Vanesa / Pérez García, Cristina / Fernández Morales, Marta / Valle Feijoo Begoña Rodríguez Ferreira, María Lorena María / Gómez-Junyent, Joan / Villar-García, Judit / López-Montesinos, Inmaculada / Arrieta-Aldea, Itziar / Rial-Villavecchia, Abora / García Vázquez, Elisa / Roura Piloto, Aychel Elena / Moral Escudero, Encarnación / Hernández Torres, Alicia / Albendín Iglesias, Helena / Vinuesa García, David / Martínez Montes, Clara / De la Hera Fernández, Francisco Javier / Anguita Santos, Francisco / Ruiz Sancho, Andrés / Díaz de Brito Fernández, Vicens / Sanmarti Vilamala, Montserrat / España Cueto, Sergio / Molina Morant, Daniel / González-Cuevas, Araceli / Chara Cervantes, Joel Elías / Policarpo Torres, Guillem / Ortega Montoliu, Meritxell / Angerri Nadal, Mònica / De Genover Gil, Ariadna / Patera, Eleni / Godoy Lorenzo, Rita / Zioga, Evangelia Anna María / Isern Fernández, Virginia / Sabbagh Fajardo, Carlos Enrique / Ferrer Ribera, Ana / Bea Serrano, Carlos / Oltra Sempere, Rosa / Vela Bernal, Sara / Albiol Viñals, Paloma / Pedromingo Kus, Miguel / Garcinuño, María Ángeles / Fiorante, Silvana / Pérez Pinto, Sergio / de la Vega, Alexandra / Fariñas Álvarez, María Carmen / González Rico, Claudia / Arnaiz de las Revillas, Francisco / Giménez, Teresa / Calvo, Jorge / Meije Castillo, Yolanda / Duarte Borges, Alejandra / Pareja Coca, Júlia / Clemente Presas, Mercedes / Sanz Salvador, Xavier / Pérez Rodríguez, Ma Teresa / Sousa, Adrián / Pérez González, Alexandre / Longueira, Rebeca / Araujo, Alejandro / Alonso Martínez, Blanca / García Escudero, Laura / Lidia Kamel Rey, Sara / Roa Alonso, David / Avilés Parra, Juan Pablo / Pelegrín Senent, Iván / Rouco Esteves Marques, Rosana / Raich Montiu, Laia / Souto Higueras, Jessica / Gálvez Bobadilla, Manuel Alejandro / Parra Ruiz, Jorge / Ramos Sesma, Violeta / Velasco Fuentes, Sara / García Pereña, Laura / Lluna Carrascosa, Alfonso / Gilaberte Reyzábal, Sergio / Liébana Gómez, Mónica / Salillas Hernando, Juan / Serrano Martínez, Alberto / Torralba González de Suso, Miguel / Martínez Martín, Patricia / Rábago Lorite, Isabel / González-Ruano Pérez, Patricia / Pérez-Monte Mínguez, Beatriz / García Flores, Ángeles / Comas Casanova, Pere / Martín Plata, Andrea / Santana Báez, Sergio Manuel / Sanz Peláez, Oscar / Mohamed Ramírez, Karim / Robaina Bordón, José María / Vílchez Rueda, Helem Haydeé / Riera Jaume, Melchor / Mut Ramon, Gemma / Gavalda Manso, Meritxell / Planas Bibiloni, Lluis / Castelo Corral, Laura / Ramos Merino, Lucía / Sánchez Vidal, Efrén / Rodríguez Mayo, María / Míguez Rey, Enrique / García de Lomas Guerrero, José M. / De la Torre Lima, Javier / Correa Ruiz, Ana / Fernández Sánchez, Fernando / Jiménez-García, Nicolás / Sierra-Monzón, José Luis / Gracia-Tello, Borja / Hernández-Bonaga, María / Pellejero, Galadriel / Asín-Corrochano, Marta / Boix Palop, Lucia / Calbo, Esther / Badía, Cristina / Dietl, Beatriz / Lucía, Gómez / Domínguez-Castellano, Ángel / Ríos-Villegas, María José / del Toro, María D. / Palacios Baena, Zaira R. / Salamanca-Rivera, Elena / Marín, Elena / Almadana, Virginia / Pérez-Galera, Salvador / González-Iglesias, Luisa / Abelenda-Alonso, Gabriela / Álvarez-Pouso, Claudia / Escrihuela, Francesc / Gudiol, Carlota / Lorenzo-Esteller, Laia / Niubó, Jordi / Podzamczer, Daniel / Pujol, Miquel / Rombauts, Alexander / Salvert Lletí, Miguel / Gil Sánchez, Ricardo / Jiménez Escrig, Marta / Parra Gómez, Laura / Tasias Pitarch, Mariona / Navarro Vilasaró, Marta / Machado Sicilia, María Luisa / Gomila Grange, Aina / Calzado Isbert, Sonia / Carrasco Antón, Nerea / Petkova-Saiz, Elizabet / Cabello Úbeda, Alfonso / Górgolas Hernández-Mora, Miguel / Sánchez-Pernaute, Olga / Dueñas Gutiérrez, Carlos / Martin Guerra, Javier / Castrodeza Sanz, José Javier / Fernández Espinilla, Virginia / Rodríguez Fernández, Laura / González-Moreno, Juan / Villoslada Gelabert, Aroa / Ribot Sanso, María Antonia / Fernández-Baca, María Victoria / Hernández Milian, Almudena / Morán Rodríguez, Miguel Ángel / Ortiz de Zárate Ibarra, Zuriñe / Portu Zapirain, José Joaquin / Saez de Adana Arroniz, Ester / Gainzarain Arana, Juan Carlos / Meca Birlanga, Olga / del Amor Espín, Ma Jesús / Viqueira González, Montserrat / García García, Josefina / Martínez Madrid, Onofre / Bernal Morell, Enrique / Alcaraz, Antonia / Muñoz, Ángeles / Pina, Ignacio / de la Rosa, Vicente / Caínzos Romero, Tamara / Sánchez Trigo, Sabela / Mariño Callejo, Ana Isabel / Álvarez Díaz, Hortensia / Valcarce Pardeiro, Nieves / Sánchez Serrano, Adriana / Piñar Cabezos, Diana / García Villalba, Eva Pilar / Aguayo Jiménez, Carmen / Ruíz Campuzano, María / Naranjo Velasco, Virginia / Santos Peña, Marta / Mora Delgado, Juan / Sevilla Moreno, Israel / Lojo Cruz, Cristina / Kortajarena Urkola, Xabier / Iribarren Loyarte, José Antonio / Bustinduy Odriozola, María Jesús / Ibarguren Pinilla, Maialen / Álvarez Rodríguez, Ignacio / Martínez Marcos, Francisco Javier / Rodríguez Gómez, Francisco Javier / Asschert Agüero, Isabel / Muñoz Beamud, Francisco / Ruiz Reina, Antonio José / Llenas-García, Jara / González-Cuello, Inmaculada / Hellín-Valiente, Elena / Martínez Birlanga, Esther / Tafalla Torres, José Manuel / Calderón Parra, Jorge / Escudero López, Gabriela / Gutiérrez Martín, Isabel / Andrés Eisenhofer, Ane / García Prieto, Sonia / Álvarez Franco, Raquel / Roger Zapata, Daniel / Martínez Cifre, Blanca / Aranda Rife, Elena / Martín Rubio, Irene / Barbosa Ventura, André / Garrido, Javier / Gonzalo, Concepción / Piñero, Iván / de la Cruz Felipe, Nieves / Talavera García, Eva / Lamata Subero, Marta / Mendoza Roy, Paula / García de Carlos, María Soledad / Lajusticia Aisa, Justo / Arteche Eguizabal, Lorea / Urrutia Losada, Ainhoa / Domingo Echaburu, Saioa / Cuadros Tito, Pedro Ángel / Orbe Narváez, Gurutz / Liébana Martos, Ma del Carmen / Roldán Fontana, Carolina / Herrero Rodríguez, Carmen / Duro Ruiz, Gaspar / Pérez Parra, Santiago / Mera Fidalgo, Arantzazu / Hortos Alsina, Miquel / Alberich Conesa, Ana / Bladé Vidal, Lourdes / Merchante Gutiérrez, Nicolás / León Jiménez, Eva / Espíndola Gómez, Reinaldo / Erostarbe Gallardo, María / Martínez Pérez-Crespo, Pedro / Cisneros, José Miguel / Aguilar-Guisado, Manuela / Aldabó, Teresa / Bueno, Claudio / Cordero-Matía, Elisa / Escoresca, Ana / Infante, Carmen / Guillermo, Martín / Salto, Sonsoles / Gioia, Francesca / Vizcarra, Pilar / Fortún Abete, Jesús / Martín Dávila, Pilar / Moreno Guillén, Santiago / Oteo Revuelta, José A. / García-García, Concepción / Santibañez Sáenz, Paula / Cervera Acedo, Cristina / Azcona Gutiérrez, José M. / Reguera Iglesias, José María / Plata Ciezar, Antonio / Valiente de Santis, Lucia / Sobrino Diaz, Beatriz / Ruiz Mesa, Juan Diego

Clinical Microbiology and Infection ; ISSN 1198-743X

a multicentre cohort study (SAM-COVID-19)

2020

Keywords	Microbiology (medical) ; Infectious Diseases ; General Medicine ; covid19
Language	English
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
DOI	10.1016/j.cmi.2020.08.010
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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