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  1. Article ; Online: Recent studies on non-invasive biomarkers useful in biliary atresia - a literature review.

    Lew-Tusk, Anna / Pęksa, Marta / Stachowicz-Stencel, Teresa

    Acta biochimica Polonica

    2023  Volume 70, Issue 3, Page(s) 475–480

    Abstract: The aim of this review is to specify new potential reliable and non-invasive methods for the diagnosis of biliary atresia (BA) that could shorten the way to diagnose BA, and finally the surgical treatment. Apart from the biomarkers that have been proven ... ...

    Abstract The aim of this review is to specify new potential reliable and non-invasive methods for the diagnosis of biliary atresia (BA) that could shorten the way to diagnose BA, and finally the surgical treatment. Apart from the biomarkers that have been proven helpful and are used nowadays in neonatal wards, there are several new potential biomarkers that researchers have found to be helpful in the diagnosis of biliary atresia. Circulating microRNAs, matrix metalloproteinase-7, stool proteins, interleukin-33, Th17-associated cytokines, urinary metabolomics, anti-smooth muscle antibodies, heat shock proteins 90 and positive biliary epithelial cells CD56 are among those presented in this summary. These markers may play a new significant role in BA diagnosis. The described methods include Nomogram, Circulating microRNAs (miRNAs), Matrix metalloproteinase-7 (MMP-7), Stool proteins, Interleukin-33 (IL-33), Th17-associated cytokines, Alpha-aminoadipic acid and N-acetyl-d-mannosamine in urine, Anti-smooth muscle antibodies (ASMA), Heat shock proteins 90 (HSP90), Positive biliary epithelial cells CD56.
    MeSH term(s) Infant, Newborn ; Humans ; Biliary Atresia/diagnosis ; HSP90 Heat-Shock Proteins ; Interleukin-33 ; Matrix Metalloproteinase 7 ; Autoantibodies ; Biomarkers ; Cytokines ; MicroRNAs
    Chemical Substances HSP90 Heat-Shock Proteins ; Interleukin-33 ; Matrix Metalloproteinase 7 (EC 3.4.24.23) ; Autoantibodies ; Biomarkers ; Cytokines ; MicroRNAs
    Language English
    Publishing date 2023-08-24
    Publishing country Poland
    Document type Review ; Journal Article
    ZDB-ID 595762-x
    ISSN 1734-154X ; 0001-527X
    ISSN (online) 1734-154X
    ISSN 0001-527X
    DOI 10.18388/abp.2020_6858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Loss of E-Cadherin Staining Continuity in the Trophoblastic Basal Membrane Correlates with Increased Resistance in Uterine Arteries and Proteinuria in Patients with Pregnancy-Induced Hypertension.

    Pęksa, Marta / Kamieniecki, Alexandra / Gabrych, Anna / Lew-Tusk, Anna / Preis, Krzysztof / Świątkowska-Freund, Małgorzata

    Journal of clinical medicine

    2022  Volume 11, Issue 3

    Abstract: Pregnancy-induced hypertension (PIH), especially when complicated with pre-eclampsia (PE), could be a life-threatening complication of pregnancy. Pre-eclampsia is one of the leading causes of perinatal morbidity and mortality in women. Pre-eclampsia is ... ...

    Abstract Pregnancy-induced hypertension (PIH), especially when complicated with pre-eclampsia (PE), could be a life-threatening complication of pregnancy. Pre-eclampsia is one of the leading causes of perinatal morbidity and mortality in women. Pre-eclampsia is mainly characterized by hypertension and kidney damage with proteinuria. Abnormal placentation and altered structure of the placental barrier are believed to participate in the pathogenesis of pregnancy-induced hypertension, leading to PE. In the current study, we aimed to analyze the immunohistochemical expression pattern of E-cadherin and p120, two markers of epithelial-mesenchymal transition, in placental samples derived from a group of 55 patients with pregnancy-induced hypertension, including pre-eclampsia and 37 healthy pregnant controls. The results were correlated with the presence of an obtained early uterine artery flow notching during diastole on Doppler ultrasound. We observed a higher frequency of discontinuous E-cadherin staining in the basement membrane of syncytiotrophoblast in patients with PIH/PE compared to controls (
    Language English
    Publishing date 2022-01-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11030668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Odosobniony guz wlóknisty przestrzeni zaotrzewnowej u clzarnej--opis przypadku.

    Peksa, Marta / Boćkowski, Maciej / Preis, Krzysztof

    Ginekologia polska

    2011  Volume 82, Issue 5, Page(s) 382–385

    Abstract: Solitary fibrous tumor (SFT) is a rare, usually benign tumor Most cases occur on the pleura, being less frequent at other serosal sites. We present a case of a large retroperitoneal tumor with no accompanying clinical symptoms, which was detected due to ... ...

    Title translation Solitary fibrous tumor of the retroperitoneum in pregnancy: case report.
    Abstract Solitary fibrous tumor (SFT) is a rare, usually benign tumor Most cases occur on the pleura, being less frequent at other serosal sites. We present a case of a large retroperitoneal tumor with no accompanying clinical symptoms, which was detected due to apparent abdominal asymmetry in a 24-year-old woman at 16 weeks of gestation. The MRI scan taken at 20 weeks demonstrated a retroperitoneal mass measuring 25 cm in length. The tumor was surgically removed at 24 weeks of gestation. The final diagnosis was established on the basis of the anatomopathological examination supplemented by immunohistochemical phenotyping.
    MeSH term(s) Adult ; Female ; Humans ; Pregnancy ; Pregnancy Complications, Neoplastic/diagnosis ; Pregnancy Complications, Neoplastic/surgery ; Pregnancy Outcome ; Retroperitoneal Neoplasms/diagnosis ; Retroperitoneal Neoplasms/surgery ; Solitary Fibrous Tumors/diagnosis ; Solitary Fibrous Tumors/surgery ; Treatment Outcome
    Language Polish
    Publishing date 2011-05
    Publishing country Poland
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 130894-4
    ISSN 0017-0011
    ISSN 0017-0011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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