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  1. Article ; Online: New Markers

    Pınar Ciragil / Ergul Belge Kurutas / Meral Miraloglu

    Disease Markers, Vol

    Urine Xanthine Oxidase and Myeloperoxidase in the Early Detection of Urinary Tract Infection

    2014  Volume 2014

    Abstract: Objectives. The aim of this study was to evaluate if xanthine oxidase and myeloperoxidase levels quantitation method may alternate routine culture method, which takes more time in the diagnosis of urinary tract infections. Material and Methods. Five ... ...

    Abstract Objectives. The aim of this study was to evaluate if xanthine oxidase and myeloperoxidase levels quantitation method may alternate routine culture method, which takes more time in the diagnosis of urinary tract infections. Material and Methods. Five hundred and forty-nine outpatients who had admitted to Clinic Microbiology Laboratory were included in the study. The microorganisms were identified by using VITEK System. The urine specimens that were negative from the quantitative urine culture were used as controls. The activities of MPO and XO in spot urine were measured by spectrophotometric method. Results. Through the urine cultures, 167 bacteria were isolated from 163 urine specimens; 386 cultures yielded no bacterial growth. E. coli was the most frequent pathogen. In infection with E. coli both XO and MPO levels were increased the most. The sensitivity, specificity, positive predictive value, and negative predictive value for XO were 100%, 100%, 100%, and 100%, respectively. These values for MPO were 87%, 100%, 100%, and 94%, respectively. Conclusion. These data obtained suggest that urine XO and MPO levels may be new markers in the early detection of UTI.
    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Oxidative Stress in Patients with Chronic Hepatitis B and C

    Pınar Çıragil / Ergül Belge Kurutaş / Ömer Faruk Kökoğlu / Murat Aral

    Balkan Medical Journal, Vol 28, Iss 03, Pp 300-

    2011  Volume 303

    Abstract: Objective: Hepatitis B and hepatitis C virus infections are extensively seen throughout the world. Disturbances in the antioxidant system and oxidative stress may play a role in the pathogenesis of chronic liver diseases. The aim of this study was to ... ...

    Abstract Objective: Hepatitis B and hepatitis C virus infections are extensively seen throughout the world. Disturbances in the antioxidant system and oxidative stress may play a role in the pathogenesis of chronic liver diseases. The aim of this study was to evaluate the oxidant/antioxidant status in the serum of patients with chronic hepatitis B (CHB) and C (CHC).Material and Methods: Twenty patients with CHB, 20 with CHC and 30 healthy volunteers were included in this study. Catalase (CAT), superoxide dismutase (SOD) activities and malondialdehyde (MDA) levels were measured in all patients and control group specthrophotometrically.Results: While CAT and SOD activities were significantly lower in patients with CHC, these enzymes were significantly higher in patients with CHB compared to controls. However, MDA levels were increased in each patient group as compared to the control group. Also, antioxidant enzyme activities were found to be significantly lower and MDA levels were higher in patients with CHC, compared to patients with CHB.Conclusion: We considered that insufficiency of antioxidant barrier may cause oxidative stress in patients with CHB and CHC, so antioxidant treatment should be useful for these patients.
    Keywords Medicine ; R
    Subject code 610
    Language English
    Publishing date 2011-09-01T00:00:00Z
    Publisher Galenos Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Serum Levels of TNF-α, IFN-γ, IL-6, IL-8, IL-12, IL-17, and IL-18 in Patients With Active Psoriasis and Correlation With Disease Severity

    Ozer Arican / Murat Aral / Sezai Sasmaz / Pinar Ciragil

    Mediators of Inflammation, Vol 2005, Iss 5, Pp 273-

    2005  Volume 279

    Keywords Pathology ; RB1-214 ; Medicine ; R
    Language English
    Publishing date 2005-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Serum Levels of TNF-α, IFN-γ, IL-6, IL-8,IL-12, IL-17, and IL-18 in Patients With Active Psoriasis andCorrelation With Disease Severity

    Pinar Ciragil / Sezai Sasmaz / Murat Aral / Ozer Arican

    Mediators of Inflammation, Vol 2005, Iss 5, Pp 273-

    2005  Volume 279

    Keywords Pathology ; RB1-214 ; Medicine ; R ; DOAJ:Pathology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2005-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The Effects of Oxidative Stress in Urinary Tract Infection

    Ergul Belge Kurutas / Pınar Ciragil / Mustafa Gul / Metin Kilinc

    Mediators of Inflammation, Vol 2005, Iss 4, Pp 242-

    2005  Volume 244

    Keywords Pathology ; RB1-214 ; Medicine ; R
    Language English
    Publishing date 2005-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: The Effects of Oxidative Stress in Urinary Tract Infection

    Metin Kilinc / Mustafa Gul / Pınar Ciragil / Ergul Belge Kurutas

    Mediators of Inflammation, Vol 2005, Iss 4, Pp 242-

    2005  Volume 244

    Keywords Pathology ; RB1-214 ; Medicine ; R ; DOAJ:Pathology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2005-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Comparison of Effects of Smoking and Smokeless Tobacco “Maras Powder” Use on Humoral Immune System Parameters

    Mustafa Gul / Pınar Ciragil / Mustafa Celik / Hasan Cetin Ekerbicer / Murat Aral

    Mediators of Inflammation, Vol

    2006  Volume 2006

    Keywords Pathology ; RB1-214 ; Medicine ; R ; DOAJ:Pathology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2006-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The Effects of Oxidative Stress in Urinary Tract Infection DuringPregnancy

    Murat Aral / Metin Kilinc / Mustafa Gul / Ergul Belge Kurutas / Pinar Ciragil / Alanur Guven

    Mediators of Inflammation, Vol 2005, Iss 5, Pp 309-

    2005  Volume 311

    Keywords Pathology ; RB1-214 ; Medicine ; R ; DOAJ:Pathology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2005-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: The Effects of Oxidative Stress in Urinary Tract Infection During Pregnancy

    Pinar Ciragil / Ergul Belge Kurutas / Mustafa Gul / Metin Kilinc / Murat Aral / Alanur Guven

    Mediators of Inflammation, Vol 2005, Iss 5, Pp 309-

    2005  Volume 311

    Keywords Pathology ; RB1-214 ; Medicine ; R
    Language English
    Publishing date 2005-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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