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Article ; Online: Temporary hypoxemia at high altitude in an intensive care unit physician

Kamal P Sharma

SAGE Open Medical Case Reports, Vol

2023 Volume 11

Abstract: A 42-year-old pediatric intensive care unit physician traveled to Nepal and took a helicopter trip to Everest Base Camp. The helicopter reached an altitude of 5500 m during flight and descended at different destinations with varying altitudes. At Hotel ... ...

Abstract	A 42-year-old pediatric intensive care unit physician traveled to Nepal and took a helicopter trip to Everest Base Camp. The helicopter reached an altitude of 5500 m during flight and descended at different destinations with varying altitudes. At Hotel Everest View at 3820 m, his oxygen saturation was 79%. He had mild tachypnea and deep breathing but was able to walk around, jump, and take photographs. He returned to Kathmandu (altitude, 1324 m) without using any supplemental oxygen during the entire trip. Based on calculations with the alveolar gas equation, he observed that he and his fellow passengers probably had hypoxemia during the trip. In summary, temporary hypoxemia associated with high altitude in healthy individuals without cardiorespiratory compromise may not require oxygen therapy. In contrast, intensive care unit patients who have respiratory failure may have similar oxygen saturation levels but may require oxygen therapy and mechanical ventilation. The oxygen saturation level must be interpreted in consideration of the clinical scenario before deciding about the need for oxygen therapy.
Keywords	Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: SYNERGISTIC ROLE OF SELECTIVE HERBAL COMBINATIONS WITH ALLOPATHIC DRUGS AMONG PATIENTS OF CHRONIC DISEASES AND WAY FORWARD FOR COVID-19 PATIENTS

K P Sharma

Indian Journal of Environmental Sciences 24(1) 43-49

2020

Abstract: Herbal preparations in combination of allopathic drugs recommended by physicians were found highly effective to patients sufferings from diabetes, heart disease, asthma and joint pain. The application of okhra mucilage results instant relief on skin burn ...

Abstract	Herbal preparations in combination of allopathic drugs recommended by physicians were found highly effective to patients sufferings from diabetes, heart disease, asthma and joint pain. The application of okhra mucilage results instant relief on skin burn encountered in day to day work in the Indian kitchen The author is grateful to his better half Dr. Subhasini, formerly Professor, Zoology Department, Univ. of Rajasthan, Jaipur; Dr. Shweta Sharma formerly Woman Scientist of DST, New Delhi and UGC, New Delhi; close relatives and friends for volunteering and time to time sharing prognosis during trials of herbal preparations with and without allopathic drugs.
Keywords	Allopathic drugs ; herbal treatment ; synergistic effect ; diabetes ; hyperlipidaemia ; creatinine ; uric acid ; hypertension ; asthma ; joint pain ; burn ; covid19
Publishing date	2020-01-03
Publishing country	eu
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact of imparting emotional intelligence skills training program to enhance emotional intelligence and work stress among staff nurses of tertiary care hospital of North Gujarat

P Sharma / Kajal Srivastava / J Landge / S Vyas

Medical Journal of Dr. D.Y. Patil Vidyapeeth, Vol 16, Iss 3, Pp 348-

2023 Volume 352

Abstract: Context: Nurses play a pivotal role in patient care and at the same time, face stressful situations due to workload, so the need of the hour is to create awareness about emotional intelligence (EI) among nurses to tide over such situations. Aims: This ... ...

Abstract	Context: Nurses play a pivotal role in patient care and at the same time, face stressful situations due to workload, so the need of the hour is to create awareness about emotional intelligence (EI) among nurses to tide over such situations. Aims: This study aimed (1) to measure baseline levels of EI in the control and intervention group of staff nurses, (2) to find the association between the sociodemographic factors and EI, (3) to give EI training skills program to the experimental group, (4) to measure any enhancement in EI Skills after the intervention, and (4) to assess any improvement in work performance (WP) after EI intervention. Settings and Design: An experimental study was conducted among nurses working in GMERS Hospital, Patan, who were working in critical care units and general hospital wards. Materials and Methods: One-third of nurses from each of the two blocks were taken (convenience sampling) from the two blocks (critical care units and general units), i.e., 24 and 42 nurses, respectively, and allocated into experimental and control groups, respectively. Questionnaire containing questions related to sociodemographic variables, the Schutte Self-Report EI test, and WP survey questionnaire by the University of Michigan Health System were used. Statistical Analysis Used: Quantitative data were summarized using means and standard deviation. The data were assessed for normality and suitable tests such as t-test and paired t-test were used. Results: A significant enhancement in mean EI score i.e 145.16±5.938 after intervention from base mean EI score of 132.42±4.21 was noticed. Furthermore, the job performance showed a statistically significant improvement after EI Intervention. None of the sociodemographic variables showed a statistically significant association with the EI scores of intervention group. Conclusions: The Study highlights the importance of EI Training among Staff nurses as an essential part of their training program, to cope up with stress level in their day to day life and this training ...
Keywords	emotional intelligence ; nurses ; tertiary care hospital ; Medicine ; R
Subject code	796
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Climate sensitivity of the summer runoff of two glacierised Himalayan catchments with contrasting climate

S. Laha / A. Banerjee / A. Singh / P. Sharma / M. Thamban

Hydrology and Earth System Sciences, Vol 27, Pp 627-

2023 Volume 645

Abstract: The future changes in runoff of Himalayan glacierised catchments will be determined by the local climate forcing and the climate sensitivity of the runoff. Here, we investigate the sensitivity of summer runoff to precipitation and temperature changes in ... ...

Abstract	The future changes in runoff of Himalayan glacierised catchments will be determined by the local climate forcing and the climate sensitivity of the runoff. Here, we investigate the sensitivity of summer runoff to precipitation and temperature changes in the winter-snow-dominated Chandra (the western Himalaya) and summer-rain-dominated upper Dudhkoshi (the eastern Himalaya) catchments. We analyse the interannual variability of summer runoff in these catchments during 1980–2018 using a semi-distributed glacio–hydrological model, which is calibrated with the available runoff and glacier mass-balance observations. Our results indicate that despite the contrasting precipitation regimes, the catchments have a similar runoff response: the summer runoff from the glacierised parts of both catchments is sensitive to temperature changes and insensitive to precipitation changes; the summer runoff from the non-glacierised parts of the catchments has the exact opposite pattern of sensitivity. The precipitation-independent glacier contribution stabilises the catchment runoff against precipitation variability to some degree. The estimated sensitivities capture the characteristic “peak water” in the long-term mean summer runoff, which is caused by the excess meltwater released by the shrinking ice reserve. As the glacier cover depletes, the summer runoff is expected to become more sensitive to precipitation forcing in these catchments. However, the net impact of the glacier loss on the catchment runoff may not be detectable, given the relatively large interannual runoff variability in these catchments.
Keywords	Technology ; T ; Environmental technology. Sanitary engineering ; TD1-1066 ; Geography. Anthropology. Recreation ; G ; Environmental sciences ; GE1-350
Subject code	550
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Copernicus Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Influence of metal/composite interface on the damage behavior and energy absorption mechanisms of FMLs against projectile impact

Sanan H. Khan / Ankush P. Sharma

Defence Technology, Vol 18, Iss 3, Pp 441-

2022 Volume 456

Abstract: This paper focuses on the interface failure in metal/GFRP laminates on account of the high-velocity impact phenomenon by a hemispherical projectile. The study considers three laminates in which the failure inside the 8-layer 0/90 GFRP laminate is ... ...

Abstract	This paper focuses on the interface failure in metal/GFRP laminates on account of the high-velocity impact phenomenon by a hemispherical projectile. The study considers three laminates in which the failure inside the 8-layer 0/90 GFRP laminate is compared with the other two laminates that include metal layers in their layup configuration. The metal layers were placed on the top and bottom on one type of laminates while in the other additional metal layers are placed symmetrically inside the layup as well. They were subjected to high-velocity impact by a hemispherical projectile at different energy levels and the idea is not to perforate the laminate configuration instead to account for the damage incurred in these laminates and the role of metal layers in providing resistance to damage within these laminates. The study utilizes experimental findings and proposes a rate-dependent Finite Element (FE) model consisting of the Hashin-Puck failure scheme for composite and the Johnson-Cook damage model for metal layers. The results of the model satisfactorily agree with their experimental counterparts and provide valuable insight into the damage resistance inside the laminates. It has been observed that the 8-layer GFRP laminate was good in terms of elastic recovery and prevention of propagation of damage inside the laminates only, till the impact energy was lower. For higher impact energy, they show poor damage resistance as the fiber failure is triggered in them. However, laminates with metal layers are shown to protect the laminate by dissipating energy in the delamination of metal/GFRP interface, shear failure of the metal layer, and on account of metal plasticity. The study further shows that the through-thickness compressive stresses were responsible for the failure of laminates and also triggering the delamination in them. A damage energy study was performed to investigate the amount of energy dissipating in various failure modes like delamination, matrix cracking, fiber failure, etc.
Keywords	High-velocity impact ; FML ; Delamination ; Abaqus ; Military Science ; U
Subject code	600
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	KeAi Communications Co., Ltd.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Alkaline Stable Anion Exchange Membranes Based on Cross-Linked Poly(arylene ether sulfone) Bearing Dual Quaternary Piperidines for Enhanced Anion Conductivity at Low Water Uptake

Prem P. Sharma / Yeeun Jeon / Dukjoon Kim

Molecules, Vol 27, Iss 364, p

2022 Volume 364

Abstract: Alkaline stable anion exchange membranes based on the cross-linked poly(arylene ether sulfone) grafted with dual quaternary piperidine (XPAES-DP) units were synthesized. The chemical structure of the synthesized PAES-DP was validated using 1 H-NMR and FT- ...

Abstract	Alkaline stable anion exchange membranes based on the cross-linked poly(arylene ether sulfone) grafted with dual quaternary piperidine (XPAES-DP) units were synthesized. The chemical structure of the synthesized PAES-DP was validated using 1 H-NMR and FT-IR spectroscopy. The physicochemical, thermal, and mechanical properties of XPAES-DP membranes were compared with those of two linear PAES based membranes grafted with single piperidine (PAES-P) unit and conventional trimethyl amine (PAES-TM). XPAES-DP membrane showed the ionic conductivity of 0.021 S cm −1 at 40 °C which was much higher than that of PAES-P and PAES-TM because of the possession of more quaternary ammonium groups in the cross-linked structure. This cross-linked structure of the XPAES-DP membrane resulted in a higher tensile strength of 18.11 MPa than that of PAES-P, 17.09 MPa. In addition, as the XPAES-DP membrane shows consistency in the ionic conductivity even after 96 h in 3 M KOH solution with a minor change, its chemical stability was assured for the application of anion exchange membrane fuel cell. The single-cell assembled with XPAES-DP membrane displayed a power density of 109 mWcm −2 at 80 °C under 100% relative humidity.
Keywords	anion exchange membrane ; ionic conductivity ; poly(arylene ether sulfone) ; alkaline stability ; crosslink ; fuel cell ; Organic chemistry ; QD241-441
Subject code	660
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genomic resources and toolkits for developmental study of whip spiders (Amblypygi) provide insights into arachnid genome evolution and antenniform leg patterning

Guilherme Gainett / Prashant P. Sharma

EvoDevo, Vol 11, Iss 1, Pp 1-

2020 Volume 18

Abstract: Abstract Background The resurgence of interest in the comparative developmental study of chelicerates has led to important insights, such as the discovery of a genome duplication shared by spiders and scorpions, inferred to have occurred in the most ... ...

Abstract	Abstract Background The resurgence of interest in the comparative developmental study of chelicerates has led to important insights, such as the discovery of a genome duplication shared by spiders and scorpions, inferred to have occurred in the most recent common ancestor of Arachnopulmonata (a clade comprising the five arachnid orders that bear book lungs). Nonetheless, several arachnid groups remain understudied in the context of development and genomics, such as the order Amblypygi (whip spiders). The phylogenetic position of Amblypygi in Arachnopulmonata posits them as an interesting group to test the incidence of the proposed genome duplication in the common ancestor of Arachnopulmonata, as well as the degree of retention of duplicates over 450 Myr. Moreover, whip spiders have their first pair of walking legs elongated and modified into sensory appendages (a convergence with the antennae of mandibulates), but the genetic patterning of these antenniform legs has never been investigated. Results We established genomic resources and protocols for cultivation of embryos and gene expression assays by in situ hybridization to study the development of the whip spider Phrynus marginemaculatus. Using embryonic transcriptomes from three species of Amblypygi, we show that the ancestral whip spider exhibited duplications of all ten Hox genes. We deploy these resources to show that paralogs of the leg gap genes dachshund and homothorax retain arachnopulmonate-specific expression patterns in P. marginemaculatus. We characterize the expression of leg gap genes Distal-less, dachshund-1/2 and homothorax-1/2 in the embryonic antenniform leg and other appendages, and provide evidence that allometry, and by extension the antenniform leg fate, is specified early in embryogenesis. Conclusion This study is the first step in establishing P. marginemaculatus as a chelicerate model for modern evolutionary developmental study, and provides the first resources sampling whip spiders for comparative genomics. Our results suggest that ...
Keywords	Arachnida ; Arachnopulmonata ; Gene duplication ; Paralogs ; Leg gap genes ; Sensory biology ; Evolution ; QH359-425
Subject code	572
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Floral polymorphism and scanning electron microscopy determination in relation to climatic influence on Solanum nigrum L.

Chandra KANTA / Ishwar P. SHARMA

Notulae Scientia Biologicae, Vol 12, Iss

2020 Volume 2

Abstract: Growing concern about climatic influence on plants reproductive biology leads to a recent surge. Climate affects directly floral morphology of plants on this basis current study summarizes climatic effects on floral or reproductive biology of Solanum ... ...

Abstract	Growing concern about climatic influence on plants reproductive biology leads to a recent surge. Climate affects directly floral morphology of plants on this basis current study summarizes climatic effects on floral or reproductive biology of Solanum nigrum L. Effect of summer, rainy and winter seasons were recorded on floral morphology, pollens viability & germination, pollen tube growth, fruit-set percentage during investigations which were subjected to one factorial analysis of variance (ANOVA) and least significant differences at p < 0.05. Climatic conditions affect floral morphology and produce polymorphism in specific conditions. In rainy and winter seasons, polymorphism was recorded in petals, stamens and pistil which is a first record of climatic influence on polymorphism. Rainy season reported for their maximum flowers numbers which promote a huge fruit-set percentage in open pollination as compared with self and cross pollination. This study confirms the effect of various climates on different floral parts which produce polymorphism along with growth, germination, length, etc. Scanning Electron Microscopy (SEM) study indicated the climatic variations on microscopic observations.
Keywords	climate ; floral biology ; pollen ; polymorphism ; Solanum nigrum L ; Agriculture (General) ; S1-972 ; Science (General) ; Q1-390
Subject code	580
Language	English
Publishing date	2020-06-01T00:00:00Z
Publisher	Society of Land Measurements and Cadastre from Transylvania (SMTCT)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A cross-sectional study to assess the anxiety and coping mechanism among primary caregivers of children admitted in PICU

Girraj P Sharma / Mukesh C Sharma / Remiya Mohan / Daisy Khera / V A Raghu

Journal of Family Medicine and Primary Care, Vol 12, Iss 9, Pp 2042-

2023 Volume 2046

Abstract: Introduction: PICU admission of a child may cause anxiety and stress among the caregivers. The criteria for admission to a PICU are terrifying and may legitimately cause parents to fear that their child may pass away or suffer a serious disability. They ... ...

Abstract	Introduction: PICU admission of a child may cause anxiety and stress among the caregivers. The criteria for admission to a PICU are terrifying and may legitimately cause parents to fear that their child may pass away or suffer a serious disability. They may be overburdened with stress and anxiety of illness and compliment medical information while trying to maintain a balance with other family demands. They must learn coping mechanisms and use resources to stay stable when they face challenges. Evidence on the coping mechanisms used by primary caregivers to control their stress and anxiety is scarce so this study assessed the anxiety and coping mechanism among the primary caregivers of children admitted in PICU. Materials and Methods: A cross-sectional study was conducted among 143 primary caregivers by using convenience sampling technique at PICU, AIIMS, Jodhpur, from April 31, 2021, to January 20, 2022. The participants were enrolled after obtaining informed consent and were interviewed by the researcher. Results: Study findings revealed that primary caregivers had 38% severe anxiety, 54% moderate anxiety, and 8% mild anxiety. They used emotion-focused coping (43.5%) followed by problem focused coping (37.2%) and avoidant coping (19.3%). Also, there was a significant association found between anxiety of primary caregivers and gender of the child (P = 0.012). Conclusion: Anxiety and stress are one of the expected psychological problems faced by caregivers of children admitted in PICU. Healthcare workers must make concerted attempts to support caregivers adaptive coping mechanisms, so they can retain a sense of balance.
Keywords	anxiety ; caregivers ; coping strategies ; intensive care ; Medicine ; R
Subject code	360
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Operation Soft Gold – Integration of cyber intelligence in curbing illegal Shahtoosh trade in India

A. Pragatheesh / Vinita Sharma / C.P. Sharma / H.V. Girisha

Forensic Science International: Animals and Environments, Vol 2, Iss , Pp 100048- (2022)

2022

Abstract: The fine wool Shahtoosh obtained from the Tibetan Antelope (Pantholops hodgsonii Abel, 1826) which is endemic to Tibetan Plateau, is highly valued for its rarity, warmth and lightness. The illegal trade in Shahtoosh may lead to extinction of this species. ...

Abstract	The fine wool Shahtoosh obtained from the Tibetan Antelope (Pantholops hodgsonii Abel, 1826) which is endemic to Tibetan Plateau, is highly valued for its rarity, warmth and lightness. The illegal trade in Shahtoosh may lead to extinction of this species. The Tibetan Antelope is protected from commercial trade throughout its range, both nationally and internationally thereby prohibiting any commercial use or trade of any product in India and in the international market. Though globally banned the illegal trade of Shahtoosh driven by international demand has continued to be actively operational undercover in India. In order to bypass this trade ban, the traffickers mis-declare Shahtoosh consignments as Pashmina, Cashmere or conceal by mixed them in shipments between look-alike woolen products. In the present study the illegal Shahtoosh trade was analysed from 2009 to 2020. The Wildlife Crime Control Bureau has envisaged Operation Soft Gold to curb this. A total of 62 confirmed Shahtoosh cases were detected in India from 2009 to 2020. Most of them were detected at exit points and intended for international smuggling. The Indri Gandhi International airport New Delhi in India was the most preferred airport, while Air Cargo and Air Courier were often used by the traffickers. Our analysis shows that the illegal Shahtoosh trade network is going on between the Western Asian countries, Oman, China, Japan, Pakistan, UK, Spain, Hong Kong and Switzerland are either destination or transit countries for illegal Shahtoosh products.
Keywords	Tibetan Antelope ; Shahtoosh ; OSINT ; Cyber Intelligence ; CITES ; Illegal Wildlife Trade ; Ecology ; QH540-549.5 ; Veterinary medicine ; SF600-1100
Subject code	381
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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