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  1. Article ; Online: Bacterial cellulose: A highly versatile nanomaterial.

    Martirani-VonAbercron, Sophie-Marie / Pacheco-Sánchez, Daniel

    Microbial biotechnology

    2023  Volume 16, Issue 6, Page(s) 1174–1178

    MeSH term(s) Cellulose ; Nanostructures ; Bacteria/genetics
    Chemical Substances Cellulose (9004-34-6)
    Language English
    Publishing date 2023-03-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2406063-X
    ISSN 1751-7915 ; 1751-7915
    ISSN (online) 1751-7915
    ISSN 1751-7915
    DOI 10.1111/1751-7915.14243
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  2. Article ; Online: Deceased Donor Liver Transplantation With Hepatic Artery Aneurysm.

    González De Godos, Andrea / Tejero Pintor, Francisco Javier / Lizarralde Capelastegui, Andrea Carlota / Pacheco Sánchez, David

    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

    2024  Volume 22, Issue 3, Page(s) 242–243

    Abstract: Few case reports have documented the long-term outcomes of liver donor aneurysms, illustrating the apprehension of transplant surgeons about using these grafts. However,the presence of an aneurysm in the donor liver should not be an absolute ... ...

    Abstract Few case reports have documented the long-term outcomes of liver donor aneurysms, illustrating the apprehension of transplant surgeons about using these grafts. However,the presence of an aneurysm in the donor liver should not be an absolute contraindication for its use. As shown in our described patient, such grafts have the potential to achieve good results.
    MeSH term(s) Humans ; Liver Transplantation ; Hepatic Artery/surgery ; Aneurysm/surgery ; Aneurysm/diagnostic imaging ; Treatment Outcome ; Tissue Donors/supply & distribution ; Male ; Donor Selection ; Middle Aged ; Computed Tomography Angiography
    Language English
    Publishing date 2024-05-02
    Publishing country Turkey
    Document type Case Reports ; Journal Article
    ZDB-ID 2396778-X
    ISSN 2146-8427 ; 1304-0855
    ISSN (online) 2146-8427
    ISSN 1304-0855
    DOI 10.6002/ect.2024.0025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6632: Show issues Location:
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  3. Article ; Online: Transcriptional organization and regulation of the

    Bernal, Patricia / Civantos, Cristina / Pacheco-Sánchez, Daniel / Quesada, José M / Filloux, Alain / Llamas, María A

    Microbiology (Reading, England)

    2023  Volume 169, Issue 1

    Abstract: The type VI secretion system (T6SS) is an antimicrobial molecular weapon that is widespread in Proteobacteria and offers competitive advantages to T6SS-positive micro-organisms. Three T6SSs have recently been described ... ...

    Abstract The type VI secretion system (T6SS) is an antimicrobial molecular weapon that is widespread in Proteobacteria and offers competitive advantages to T6SS-positive micro-organisms. Three T6SSs have recently been described in
    MeSH term(s) Type VI Secretion Systems/genetics ; Type VI Secretion Systems/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Pseudomonas putida/metabolism ; Sigma Factor/genetics ; Multigene Family ; Gene Expression Regulation, Bacterial
    Chemical Substances Type VI Secretion Systems ; Bacterial Proteins ; Sigma Factor
    Language English
    Publishing date 2023-01-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1180712-x
    ISSN 1465-2080 ; 1350-0872
    ISSN (online) 1465-2080
    ISSN 1350-0872
    DOI 10.1099/mic.0.001295
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Subtle sequence differences between two interacting σ

    Pacheco-Sánchez, Daniel / Marín, Patricia / Molina-Fuentes, Águeda / Marqués, Silvia

    The FEBS journal

    2022  Volume 289, Issue 23, Page(s) 7582–7604

    Abstract: In the strictly anaerobic nitrate reducing bacterium Aromatoleum anaerobium, degradation of 1,3-dihydroxybenzene (1,3-DHB, resorcinol) is controlled by two bacterial enhancer-binding proteins (bEBPs), RedR1 and RedR2, which regulate the transcription of ... ...

    Abstract In the strictly anaerobic nitrate reducing bacterium Aromatoleum anaerobium, degradation of 1,3-dihydroxybenzene (1,3-DHB, resorcinol) is controlled by two bacterial enhancer-binding proteins (bEBPs), RedR1 and RedR2, which regulate the transcription of three σ
    Language English
    Publishing date 2022-07-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2173655-8
    ISSN 1742-4658 ; 1742-464X
    ISSN (online) 1742-4658
    ISSN 1742-464X
    DOI 10.1111/febs.16576
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  5. Article ; Online: Small bowel obstruction caused by pericaecal hernia resolved with a laparoscopic approach.

    Plua-Muñiz, K / Sanchez-Gonzalez, J / Bailon-Cuadrado, M / Pacheco-Sanchez, D

    Annals of the Royal College of Surgeons of England

    2020  Volume 102, Issue 7, Page(s) e155–e157

    Abstract: Small bowel obstruction from internal hernias is a familiar pathology for the surgeon, with an incidence of 0.5-5.8%. However, pericaecal hernia is a very uncommon type of internal hernia. Diagnosis and early treatment are essential to avoid ... ...

    Abstract Small bowel obstruction from internal hernias is a familiar pathology for the surgeon, with an incidence of 0.5-5.8%. However, pericaecal hernia is a very uncommon type of internal hernia. Diagnosis and early treatment are essential to avoid strangulation and necrosis of the incarcerated small bowel. We report a case of an 84-year-old woman with no previous history of abdominal surgery who came to our hospital having endured 6 hours of abdominal pain and vomiting. Following physical examination and computed tomography, a diagnosis of small bowel obstruction caused by pericaecal hernia was made and emergency surgery was performed. The hernia was successfully reduced with a laparoscopic approach. Although pericaecal hernia is a rare disease, surgeons should bear it in mind as a differential diagnosis in small bowel obstruction.
    MeSH term(s) Aged, 80 and over ; Diagnosis, Differential ; Female ; Hernia, Abdominal/complications ; Hernia, Abdominal/diagnosis ; Hernia, Abdominal/surgery ; Herniorrhaphy/methods ; Humans ; Intestinal Obstruction/diagnosis ; Intestinal Obstruction/etiology ; Intestinal Obstruction/surgery ; Intestine, Small/diagnostic imaging ; Intestine, Small/surgery ; Laparoscopy/methods ; Tomography, X-Ray Computed
    Language English
    Publishing date 2020-04-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2020.0072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.234: Show issues Location:
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  6. Article ; Online: Subtle sequence differences between two interacting σ54‐dependent regulators lead to different activation mechanisms

    Pacheco‐Sánchez, Daniel / Marín, Patricia / Molina‐Fuentes, Águeda / Marques, Silvia

    The FEBS Journal. 2022 Dec., v. 289, no. 23 p.7582-7604

    2022  

    Abstract: In the strictly anaerobic nitrate reducing bacterium Aromatoleum anaerobium, degradation of 1,3‐dihydroxybenzene (1,3‐DHB, resorcinol) is controlled by two bacterial enhancer‐binding proteins (bEBPs), RedR1 and RedR2, which regulate the transcription of ... ...

    Abstract In the strictly anaerobic nitrate reducing bacterium Aromatoleum anaerobium, degradation of 1,3‐dihydroxybenzene (1,3‐DHB, resorcinol) is controlled by two bacterial enhancer‐binding proteins (bEBPs), RedR1 and RedR2, which regulate the transcription of three σ⁵⁴‐dependent promoters controlling expression of the pathway. RedR1 and RedR2 are identical over their length except for their N‐terminal tail which differ in sequence and length (six and eight residues, respectively), a single change in their N‐terminal domain (NTD), and nine non‐identical residues in their C‐terminal domain (CTD). Their NTD is composed of a GAF and a PAS domain connected by a linker helix. We show that each regulator is controlled by a different mechanism: whilst RedR1 responds to the classical NTD‐mediated negative regulation that is released by the presence of its effector, RedR2 activity is constitutive and controlled through interaction with BtdS, an integral membrane subunit of hydroxyhydroquinone dehydrogenase carrying out the second step in 1,3‐DHB degradation. BtdS sequesters the RedR2 regulator to the membrane through its NTD, where a four‐Ile track in the PAS domain, interrupted by a Thr in RedR1, and the N‐terminal tail are involved. The presence of 1,3‐DHB, which is metabolized to hydroxybenzoquinone, releases RedR2 from the membrane. Most bEBPs assemble into homohexamers to activate transcription; we show that hetero‐oligomer formation between RedR1 and RedR2 is favoured over homo‐oligomers. However, either an NTD‐truncated version of RedR1 or a full‐length RedR2 are capable of promoter activation on their own, suggesting they should assemble into homohexamers in vivo. We show that promoter DNA behaves as an allosteric effector through binding the CTD to control ΔNTD‐RedR1 multimerization and activity. Overall, the regulation of the 1,3‐DHB anaerobic degradation pathway can be described as a novel mode of bEBP activation and assembly.
    Keywords Aromatoleum ; DNA ; amino acid sequences ; bacteria ; nitrates ; oxidoreductases ; resorcinol
    Language English
    Dates of publication 2022-12
    Size p. 7582-7604.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2173655-8
    ISSN 1742-4658 ; 1742-464X
    ISSN (online) 1742-4658
    ISSN 1742-464X
    DOI 10.1111/febs.16576
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  7. Article ; Online: Orbital metastasis as the first manifestation of advanced rectal cancer.

    Bueno-Cañones, Alejandro David / Blanco-Álvarez, José Ignacio / Sarmentero-Prieto, José Carlos / Pacheco-Sánchez, David

    Cirugia espanola

    2022  Volume 100, Issue 4, Page(s) 242

    MeSH term(s) Humans ; Orbital Neoplasms/secondary ; Rectal Neoplasms/pathology
    Language English
    Publishing date 2022-04-22
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2022.03.008
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  8. Article ; Online: Femoral hernia containing the right fallopian tube: chronic pain with menstruation.

    Marcos-Santos, P / Bailon-Cuadrado, M / Choolani-Bhojwani, E / Pacheco-Sanchez, D

    Annals of the Royal College of Surgeons of England

    2019  Volume 101, Issue 7, Page(s) e157–e159

    Abstract: Femoral hernias represent less than 10% of groin hernias and appear mainly in adult women; incarceration is more usual than in other hernias. Content found within the sac is commonly small bowel or omentum. Other anatomical structures, such as appendix, ... ...

    Abstract Femoral hernias represent less than 10% of groin hernias and appear mainly in adult women; incarceration is more usual than in other hernias. Content found within the sac is commonly small bowel or omentum. Other anatomical structures, such as appendix, bladder, Meckel's diverticulum, ectopic testis, stomach and gynaecological organs are extremely unusual. A 48-year-old woman presented with intense right groin pain over 48 hours. Her past medical history revealed periodical moderate right groin pain coincident with her menstrual cycles, usually self-limited. No abdominal symptoms or fever were present. On physical examination, an incarcerated right femoral hernia was suspected. Subsequently abdominal ultrasound revealed a right femoral hernia containing an echogenic structure with conserved vascularisation. The patient underwent an emergency surgery. During the procedure the right fallopian tube and several small cysts were discovered as the hernia sac contents. As no ischaemic signs were observed, and the sac was sutured and reduced. Femoral hernioplasty was accomplished with polypropylene mesh. The postoperative course was uneventful and the patient was discharged within 24 hours. After an exhaustive literature review, we have found few cases reporting the presence of fallopian tube in adult women with femoral hernia, but none described a recurrent groin pain coinciding with menstruation, as in this case.
    MeSH term(s) Chronic Pain/etiology ; Dysmenorrhea/etiology ; Dysmenorrhea/surgery ; Fallopian Tube Diseases/etiology ; Fallopian Tubes ; Female ; Groin ; Hernia, Femoral/complications ; Hernia, Femoral/diagnosis ; Hernia, Femoral/surgery ; Herniorrhaphy ; Humans ; Middle Aged ; Ultrasonography
    Language English
    Publishing date 2019-06-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2019.0082
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  9. Article ; Online: Erratum for Pacheco-Sánchez et al., "DbdR, a New Member of the LysR Family of Transcriptional Regulators, Coordinately Controls Four Promoters in the Thauera aromatica AR-1 3,5-Dihydroxybenzoate Anaerobic Degradation Pathway".

    Pacheco-Sánchez, Daniel / Molina-Fuentes, Águeda / Marín, Patricia / Díaz-Romero, Alberto / Marqués, Silvia

    Applied and environmental microbiology

    2021  Volume 87, Issue 22, Page(s) e0192421

    Language English
    Publishing date 2021-10-28
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 223011-2
    ISSN 1098-5336 ; 0099-2240
    ISSN (online) 1098-5336
    ISSN 0099-2240
    DOI 10.1128/AEM.01924-21
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    Zs.B 201: Show issues Location:
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  10. Article ; Online: Orbital metastasis as the first manifestation of advanced rectal cancer.

    Bueno-Cañones, Alejandro David / Blanco-Álvarez, José Ignacio / Sarmentero-Prieto, José Carlos / Pacheco-Sánchez, David

    Cirugia espanola

    2021  

    Title translation Metástasis orbitaria como primera manifestación de cáncer de recto avanzado.
    Language Spanish
    Publishing date 2021-03-11
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.ciresp.2021.02.004
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